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Silo Pharma Advances Clinical Study Analyzing Effects of Psilocybin on Inflammation

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Silo Pharma (Nasdaq: SILO) announced a progress update on its clinical study at UCSF, which examines psilocybin as a treatment for conditions including Parkinson's disease, bipolar disorder, and chronic pain. The study involves therapy sessions with psilocybin and blood sample collection to analyze inflammatory activity. Data collection for Parkinson's patients is set to finish by February 2023, while bipolar and chronic pain studies are scheduled to commence in early and April 2023, respectively. The findings aim to shed light on psilocybin's therapeutic potential.

Positive
  • Clinical study at UCSF is progressing, potentially confirming psilocybin's role in treating inflammatory disorders.
  • Data collection for Parkinson's disease patients expected to complete by February 2023, showing timely progress.
  • Clinical trials could personalize psilocybin therapy using novel homing peptides and topical technology.
Negative
  • Potential risks indicated in forward-looking statements regarding the uncertainty of clinical outcomes.
  • Timeline for bipolar and chronic pain patient data collection suggests a staggered approach, which may delay comprehensive results.

Parkinson's disease, bipolar disorder, and chronic pain targeted in study

Study aims to support psilocybin as a potential therapeutic for inflammatory disorders

ENGLEWOOD CLIFFS, NJ, Jan. 10, 2023 (GLOBE NEWSWIRE) --  Silo Pharma, Inc. (Nasdaq: SILO) (“the Company”), a developmental stage biopharmaceutical company focused on merging traditional therapeutics with psychedelic research, today announced a progress update on its sponsored research study with the University of California, San Francisco (UCSF) examining psilocybin’s effect on inflammatory activity in humans. The clinical study evaluates three populations of patients suffering from Parkinson's disease, bipolar disorder, and chronic pain.

Eric Weisblum, Chief Executive Officer of Silo Pharma, commented, “The UCSF research team is making progress on the clinical trial. The data gathered from these studies could uncover the role of inflammatory activity on such conditions as Parkinson’s, Bipolar disorder and Chronic Pain. Utilizing Psilocybin in this study in a regimented dosing pattern, we hope to gain significant data both in mechanism of action and potential biomarker for personalization of psilocybin therapy.  The targeted patient populations from the study could provide support for the development and use of psilocybin as a therapeutic coupled with our novel homing peptides and topical technology.”

For each patient population, the clinical studies involve preparation therapy, two separate dosing sessions with psilocybin, and integration therapy. At the Clinical & Translational Science Institute (CTSI) at UCSF, four blood samples are collected from each participant, one at baseline before treatment begins, one at 24 hours post dosing for each dosing session, and one at a 30-day follow up. The research team is on track to complete data collection from Parkinson's disease patients by the end of February 2023. Data collection is expected to begin in early 2023 for the bipolar study, and in April 2023 for the chronic pain study patients.

The Clinical & Translational Science Institute at the University of California, San Francisco facilitates clinical and translational research to improve patient and community health. CTSI does this by providing infrastructure, services, and training to enable research to be conducted more efficiently and effectively, and in new ways. To advance its mission, the Institute develops broad coalitions and partnerships at the local, regional and national levels to enable a transformation of the research environment.

About Silo Pharma
Silo Pharma. Inc. is a development-stage biopharmaceutical company focused on merging traditional therapeutics with psychedelic research for people suffering from indications such as PTSD, Alzheimer’s disease, and other rare neurological disorders. Silo’s mission is to identify assets to license and fund the research which we believe will be transformative to the well-being of patients and the healthcare industry. For more information, visit www.silopharma.com.

Forward-Looking Statements
All statements other than statements of historical fact in this announcement are forward-looking statements that involve known and unknown risks and uncertainties and are based on current expectations and projections about future events and financial trends that the Company believes may affect its financial condition, results of operations, business strategy, and financial needs. Investors can identify these forward-looking statements by words or phrases such as "may," "will," "expect," "anticipate," "aim," "estimate," "intend," "plan," "believe," "potential," "continue," "is/are likely to" or other similar expressions. The Company undertakes no obligation to update forward-looking statements to reflect subsequent occurring events or circumstances, or changes in its expectations, except as may be required by law. Although the Company believes that the expectations expressed in these forward-looking statements are reasonable, it cannot assure you that such expectations will turn out to be correct, and the Company cautions investors that actual results may differ materially from the anticipated results and encourages investors to review other factors that may affect its future results in the Company's filings with the SEC.

Contact 
800-705-0120
investors@silopharma.com


FAQ

What is the purpose of Silo Pharma's study involving psilocybin?

The study aims to evaluate the effects of psilocybin on inflammatory activity in patients with Parkinson's disease, bipolar disorder, and chronic pain.

When is the data collection for the Parkinson's disease study expected to be completed?

Data collection for the Parkinson's disease patients is expected to be completed by the end of February 2023.

What populations are being studied in Silo Pharma's clinical trial?

The clinical trial is studying patients with Parkinson's disease, bipolar disorder, and chronic pain.

What are the next steps after the data collection for the clinical study?

Following data collection, results will be analyzed to uncover psilocybin’s therapeutic potential and inform future treatments.

How does Silo Pharma plan to personalize psilocybin therapy?

Silo Pharma intends to use data from the studies to identify biomarkers for personalizing psilocybin therapy.

Silo Pharma, Inc.

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