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Shuttle Pharmaceuticals Holdings, Inc. Announces Pricing of $4.5 Million Public Offering Priced At-The-Market Under Nasdaq Rules

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Shuttle Pharmaceuticals Holdings (Nasdaq: SHPH) has announced pricing of a $4.5 million public offering priced at-the-market. The offering includes up to 2,950,820 shares of common stock (or pre-funded warrants) and warrants at $1.525 per share and accompanying warrant. The warrants, exercisable at $1.40 per share, will expire in five years. Net proceeds will fund IND-enabling and Phase I/II clinical trials, including $2.3 million payment to Theradex Systems for Phase II trials of Ropidoxuridine. The offering is expected to close around October 31, 2024.

Shuttle Pharmaceuticals Holdings (Nasdaq: SHPH) ha annunciato il prezzo di un'offerta pubblica di 4,5 milioni di dollari, fissata in base al mercato. L'offerta include fino a 2.950.820 azioni ordinarie (o warrant pre-finanziati) e warrant a 1,525 dollari per azione e relativo warrant. I warrant, esercitabili a 1,40 dollari per azione, scadranno tra cinque anni. I proventi netti serviranno a finanziare studi clinici di abilitazione IND e Fase I/II, compreso un pagamento di 2,3 milioni di dollari a Theradex Systems per gli studi di Fase II di Ropidoxuridina. Si prevede che l'offerta si chiuda intorno al 31 ottobre 2024.

Shuttle Pharmaceuticals Holdings (Nasdaq: SHPH) ha anunciado el precio de una oferta pública de 4,5 millones de dólares, fijada en el mercado. La oferta incluye hasta 2,950,820 acciones ordinarias (o warrants pre-financiados) y warrants a 1.525 dólares por acción y warrant correspondiente. Los warrants, que se pueden ejercer a 1.40 dólares por acción, expirarán en cinco años. Los ingresos netos se destinarán a financiar ensayos clínicos de habilitación IND y Fase I/II, incluyendo un pago de 2.3 millones de dólares a Theradex Systems por los ensayos de Fase II de Ropidoxuridina. Se espera que la oferta se cierre alrededor del 31 de octubre de 2024.

셔틀 제약 홀딩스(Nasdaq: SHPH)는 450만 달러 규모의 공개 판매 가격을 시장 가격으로 발표했습니다. 이 제안에는 최대 2,950,820주(또는 미리 자금을 조달한 워런트)의 보통주 및 주당 1.525달러의 권리가 포함됩니다. 이 워런트는 주당 1.40달러로 행사할 수 있으며, 5년 후에 만료됩니다. 순수익은 IND 승인 및 1/2상 임상 시험을 자금 지원하는 데 사용됩니다. 여기에는 Ropidoxuridine의 2상 시험을 위한 Theradex Systems에 대한 230만 달러 지급이 포함됩니다. 이 제안은 2024년 10월 31일 경에 마감될 것으로 예상됩니다.

Shuttle Pharmaceuticals Holdings (Nasdaq: SHPH) a annoncé le prix d'une offre publique de 4,5 millions de dollars, fixée au prix du marché. L'offre comprend jusqu'à 2 950 820 actions ordinaires (ou warrants préfinancés) et des warrants à 1,525 dollar par action et warrant correspondant. Les warrants, exerçables à 1,40 dollar par action, expireront dans cinq ans. Les produits nets financeront les essais cliniques nécessaires à l'IND et de phase I/II, y compris un paiement de 2,3 millions de dollars à Theradex Systems pour les essais de phase II de Ropidoxuridine. La clôture de l'offre est prévue autour du 31 octobre 2024.

Shuttle Pharmaceuticals Holdings (Nasdaq: SHPH) hat den Preis für ein öffentliches Angebot in Höhe von 4,5 Millionen Dollar bekannt gegeben, das zum Marktpreis angeboten wird. Das Angebot umfasst bis zu 2.950.820 Stammaktien (oder vorfinanzierte Warrants) und Warrants zu einem Preis von 1,525 Dollar pro Aktie und dazugehörigem Warrant. Die Warrants, die zu 1,40 Dollar pro Aktie ausgeübt werden können, laufen in fünf Jahren ab. Die Nettomittel werden zur Finanzierung von IND-fähigen und Phase I/II-Studien verwendet, einschließlich einer Zahlung von 2,3 Millionen Dollar an Theradex Systems für die Phase-II-Studien zu Ropidoxuridin. Es wird erwartet, dass das Angebot um den 31. Oktober 2024 abgeschlossen wird.

Positive
  • Secured $4.5 million in funding through public offering
  • Funds allocated for advancement of clinical trials
  • Strategic partnership with Theradex Systems for Phase II trials
Negative
  • Potential dilution of existing shareholders through new share issuance
  • At-market pricing indicates possible unfavorable market conditions
  • Significant portion ($2.3M) of proceeds already committed to CRO payment

Insights

This $4.5 million public offering represents a significant dilutive event for SHPH, with the pricing at $1.525 per share being notably below recent trading levels. The inclusion of warrants with a $1.40 exercise price adds potential for further dilution. The allocation of $2.3 million to Theradex Systems for clinical trials indicates immediate cash needs for operational requirements.

The offering structure, combining common stock with warrants and pre-funded warrants, suggests challenging market conditions for capital raising. The "reasonable best efforts" basis and at-market pricing reflect current market constraints for small-cap biotech companies. With a market cap of only about $5 million, this financing significantly impacts the capital structure, potentially pressuring share prices in the near term.

GAITHERSBURG, Md., Oct. 29, 2024 (GLOBE NEWSWIRE) -- Shuttle Pharmaceuticals Holdings, Inc. (Nasdaq: SHPH) (“Shuttle Pharma” or the “Company”), a discovery and development stage specialty pharmaceutical company focused on improving outcomes for cancer patients treated with radiation therapy (RT), today announced the pricing of its "reasonable best efforts" public offering with a health-care focused institutional investor for the purchase and sale of up to 2,950,820 shares of common stock (or pre-funded warrants in lieu thereof) and warrants to purchase up to 2,950,820 shares of common stock at a combined offering price of $1.525 per share and accompanying warrant, priced at-the-market under Nasdaq rules (the “Offering”). The Company expects to receive aggregate gross proceeds of approximately $4.5 million, before deducting placement agent fees and other offering expenses, and assuming no exercise of the warrants. The warrants will have an exercise price of $1.40 per share, will be exercisable immediately and will expire five years from the issuance date.

The closing of the Offering is expected to occur on or about October 31, 2024, subject to the satisfaction of customary closing conditions. The Company intends to use the net proceeds from this Offering to fund IND-enabling and Phase I and II clinical trials of product candidates, including $2.3 million in payments that will be owed to Theradex Systems, Inc., the clinical research organization (CRO) supporting Shuttle Pharma’s Phase II clinical trials for radiation sensitizer Ropidoxuridine, and for working capital and general corporate purposes.

A.G.P./Alliance Global Partners is acting as the lead placement agent for the Offering and Boustead Securities, LLC is acting as a co-placement agent for the Offering.

The securities described above are being offered pursuant to a registration statement on Form S-1 (File No. 333-282231) previously filed with the Securities and Exchange Commission ("SEC") which was declared effective on October 29, 2024. This Offering is being made only by means of a prospectus forming part of the effective registration statement. A preliminary prospectus relating to the Offering has been filed with the SEC. An electronic copy of the final prospectus relating to the Offering may be obtained, when available, on the SEC's website located at http://www.sec.gov and may also be obtained from A.G.P./Alliance Global Partners, 590 Madison Avenue, 28th Floor, New York, NY 10022, or by telephone at (212) 624-2060, or by email at prospectus@allianceg.com.

This press release shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of these securities in any state or jurisdiction in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state or jurisdiction.

About Shuttle Pharmaceuticals Holdings, Inc.

Founded in 2012 by faculty members of the Georgetown University Medical Center, Shuttle Pharma is a discovery and development stage specialty pharmaceutical company focused on improving the outcomes for cancer patients treated with radiation therapy (RT). Our mission is to improve the lives of cancer patients by developing therapies that are designed to maximize the effectiveness of RT while limiting the side effects of radiation in cancer treatment. Although RT is a proven modality for treating cancers, by developing radiation sensitizers, we aim to increase cancer cure rates, prolong patient survival and improve quality of life when used as a primary treatment or in combination with surgery, chemotherapy and immunotherapy. For more information, please visit our website at www.shuttlepharma.com.

Safe Harbor

Statements in this press release about future expectations, plans and prospects, as well as any other statements regarding matters that are not historical facts, may constitute “forward-looking statements.” These statements include, but are not limited to, statements concerning the development of our company, the satisfaction of customary closing conditions related to the Offering, the timing of the anticipated closing of the Offering and the intended use of proceeds from the Offering. The words “anticipate,” “believe,” “continue,” “could,” “estimate,” “expect,” “intend,” “may,” “plan,” “potential,” “predict,” “project,” “should,” “target,” “will,” “would” and similar expressions are intended to identify forward-looking statements, although not all forward-looking statements contain these identifying words. Actual results may differ materially from those indicated by such forward-looking statements as a result of various important factors, including factors discussed in the “Risk Factors” section of Shuttle Pharma’s Annual Report on Form 10-K for the year ended December 31, 2023, as amended, filed with the SEC on September 4, 2024, as well other SEC filings. Any forward-looking statements contained in this press release speak only as of the date hereof and, except as required by federal securities laws, Shuttle Pharmaceuticals specifically disclaims any obligation to update any forward-looking statement, whether as a result of new information, future events or otherwise.

Shuttle Pharmaceuticals
Anatoly Dritschilo, M.D., CEO
240-403-4212
info@shuttlepharma.com

Investor Contacts
Lytham Partners, LLC
Robert Blum
602-889-9700

shph@lythampartners.com


FAQ

What is the size and price of Shuttle Pharmaceuticals (SHPH) October 2024 public offering?

The offering is $4.5 million, priced at $1.525 per share and accompanying warrant, including up to 2,950,820 shares of common stock or pre-funded warrants.

How will SHPH use the proceeds from its October 2024 offering?

The proceeds will fund IND-enabling and Phase I/II clinical trials, with $2.3 million allocated to Theradex Systems for Phase II trials of Ropidoxuridine, plus working capital and general corporate purposes.

What are the terms of the warrants in SHPH's October 2024 offering?

The warrants have an exercise price of $1.40 per share, are immediately exercisable, and will expire five years from the issuance date.

Shuttle Pharmaceuticals Holdings, Inc.

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