Welcome to our dedicated page for Serina Therapeutics news (Ticker: ser), a resource for investors and traders seeking the latest updates and insights on Serina Therapeutics stock.
Company Overview
Serina Therapeutics Inc is a clinical-stage biotechnology company dedicated to advancing treatment solutions in the fields of neurological diseases and pain management. Leveraging cutting-edge drug delivery methodologies, the company specializes in developing wholly-owned drug candidates that address complex clinical challenges. With a focus on innovative approaches and precision control in drug loading and release, Serina Therapeutics has positioned itself as a significant participant in the biopharmaceutical research landscape.
Core Technology: The POZ Platform
At the heart of Serina Therapeutics' approach lies its proprietary POZ Platform delivery technology. Designed to offer exceptional control over both the loading and release rate of therapeutic agents, the POZ Platform represents a breakthrough in overcoming the limitations posed by traditional biocompatible polymers such as polyethylene glycol (PEG). This technology is engineered to optimize the performance of challenging small molecules, potentially unlocking new avenues in drug development and delivery precision.
Product Development and Pipeline Focus
Serina Therapeutics' pipeline is built around a portfolio of drug candidates specifically developed for neurological conditions and pain management. The company’s research and development strategy emphasizes innovation and expertise in drug formulation, aiming to provide enhanced treatment options where conventional therapies have encountered obstacles. The ongoing development efforts are designed to contribute valuable insights into drug delivery mechanisms and therapeutic efficacy, reinforcing the company's status as an active innovator in clinical-stage biotechnology.
Industry Position and Competitive Landscape
Operating within a competitive and highly specialized industry, Serina Therapeutics faces the typical challenges of clinical-stage research, including intricate regulatory scrutiny and the inherent risks of drug development. However, its commitment to addressing unfulfilled medical needs through innovative delivery platforms distinguishes it from many of its peers. The company integrates advanced technology with robust scientific research, thereby establishing a unique value proposition that resonates with investors and industry analysts alike.
Business Model and Strategic Operations
Serina Therapeutics generates value primarily through its innovation-driven pipeline and intellectual property portfolio. The company's business model revolves around the development of drug candidates that may eventually contribute to improved patient outcomes in the neurology and pain domains. By focusing on internally controlled, meticulously engineered drug delivery systems, the company underscores its dedication to precision medicine and targeted therapeutic strategies. The strategic emphasis is not on immediate financial metrics but on building a resilient foundation of scientific and technological expertise, ensuring a consistent stream of innovations that may serve as milestones in clinical research.
Research and Scientific Rigor
Underpinned by a culture of scientific rigor and continuous research, Serina Therapeutics remains committed to advancing its drug delivery technologies. The company’s work is characterized by thorough preclinical studies and a gradual, evidence-based approach to clinical advancement. This methodical progression is aimed at both achieving and demonstrating clear research milestones and therapeutic potential, thereby reinforcing the company's authority and expertise within the industry.
Conclusion
In summary, Serina Therapeutics Inc stands out due to its specialized focus on neurological and pain therapeutics, its revolutionary POZ Platform technology, and a commitment to advancing clinical-stage drug candidates with precision and care. The company offers deep insights into innovative drug delivery systems and operates with a strong emphasis on research, scientific integrity, and technological advancement, making it an informative case study in clinical biotechnology.
Serina Therapeutics (NYSE: SER) announced that their Chief Development Officer, Dr. Randall Moreadith, will present groundbreaking data at the 4th LNP Formulation & Process Development Summit 2025 in Boston. The presentation, titled 'The PEG Dilemma – A Solution,' will take place on April 15, 2025, at 9:30 AM ET.
The presentation focuses on the company's innovative POZ-lipid technology, developed as an immune-silent alternative to PEG-lipids in mRNA vaccines and therapeutics. Key research findings show that Serina's POZ-lipid component in lipid nanoparticles (LNPs) demonstrated no IgM or IgG antibody response in rat studies with repeat dosing, unlike traditional PEG-lipid standards which triggered strong antibody responses.
This breakthrough is particularly significant as anti-PEG antibodies have been linked to anaphylaxis and serious adverse events in patients receiving PEGylated mRNA vaccines, including those from Pfizer and Moderna. The immune-silent nature of POZ-lipid technology could potentially revolutionize the development of safer LNP formulations for gene therapy and RNA-based medicines.
Serina Therapeutics (NYSE: SER) has secured $5 million in strategic funding to advance its lead clinical candidate SER-252 for Advanced Parkinson's disease. The financing involves issuing 965,250 shares of convertible preferred stock at $5.18 per share.
The funds will support the development of SER-252 (POZ-apomorphine), which utilizes Serina's proprietary POZ Platform™ drug optimization technology. The company aims to initiate a Phase 1 clinical trial in the fourth quarter of 2025. The therapeutic approach focuses on achieving continuous dopaminergic stimulation for potential clinical benefits in advanced Parkinson's disease patients.
Serina Therapeutics (NYSE American: SER), a clinical-stage biotech company, has announced its participation in the upcoming Jones Healthcare and Technology Innovation Conference in Las Vegas. The company's CEO Steve Ledger will deliver a presentation on April 9, 2025, at 3:00 p.m. PDT.
Serina, known for developing its proprietary POZ Platform™ drug optimization technology, will make the presentation available via live webcast for registered attendees. The presentation recording will remain accessible on-demand for a 90-day period following the event.
Serina Therapeutics (NYSE: SER) reported its full year 2024 financial results, marking significant developments in its POZ Platform™ drug optimization technology. The company secured a $10 million equity financing from JuvVentures and completed the sale of UniverXome subsidiary, eliminating $11.2 million in debt.
Financial highlights include:
- Revenue decreased to $56,000 in 2024 from $3.2 million in 2023
- Operating expenses increased to $17.1 million from $6.3 million
- Net loss of $11.1 million ($1.51 per share) compared to net income of $5.3 million in 2023
- Cash position of $3.7 million as of December 31, 2024
The company strengthened its board with two appointments and advanced its partnership with Enable Injections for SER-252 development in advanced Parkinson's disease, with Phase 1b trial expected in Q4.
Serina Therapeutics (NYSE: SER) announced that their Chief Development Officer, Dr. Randall Moreadith, will present groundbreaking data at the ACS Spring 2025 Meeting in San Diego. The presentation, focusing on their POZ Platform™ drug delivery technology, will showcase findings on their proprietary POZ-lipid technology used in lipid nanoparticles (LNPs).
Key research findings demonstrate that Serina's POZ-lipid showed no IgM or IgG antibody response in rats after repeated dosing, unlike conventional polyethylene glycol (PEG)-lipids which triggered strong antibody responses. This is particularly significant as anti-PEG antibodies have been linked to anaphylaxis and serious adverse events in patients receiving PEGylated mRNA vaccines.
This breakthrough discovery suggests potential for developing safer and more effective LNP formulations for gene therapy and RNA-based medicines.
Serina Therapeutics (NYSE American: SER) has appointed Dr. Jay Venkatesan to its Board of Directors. Dr. Venkatesan brings extensive experience in biotechnology investment and company building, most recently serving as Chairman, President, and CEO of Angion Biomedica until its 2023 merger with Elicio Therapeutics.
His notable achievements include co-founding Alpine Immune Sciences, which was acquired by Vertex Pharmaceuticals for $4.9 billion in May 2024. Dr. Venkatesan's background includes founding Ayer Capital, a healthcare investment fund, and holding positions at Brookside Capital and McKinsey & Co.
As part of this transition, Serina's co-founder Dr. Milton Harris will become Director Emeritus and Chair of the company's Scientific Advisory Board (SAB), continuing to provide guidance for the company's research and development efforts.
Serina Therapeutics (NYSE: SER) has successfully closed the second $5 million tranche of its $10 million equity financing with JuvVentures (UK) . This funding will support the advancement of SER-252, a treatment for advanced Parkinson's disease, into Phase 1 clinical trials in the second half of 2025.
The transaction involved issuing 500,000 shares at $10 per share, representing a 113% premium to the January 31, 2025 closing price. Additionally, warrants for up to 755,728 shares at $18.00 per share were issued to JuvVentures. The company's POZ Platform™ drug optimization technology enables SER-252 (POZ-apomorphine) to provide continuous dopaminergic stimulation through an innovative drug delivery system.
Serina Therapeutics (NYSE American: SER) has announced the sale of its UniverXome subsidiary, completed on December 23, 2024. The transaction eliminates $11.2 million in subsidiary-level debt, resulting in a debt-free balance sheet for Serina entering 2025.
The UniverXome subsidiary was established before Serina's reverse merger with AgeX Therapeutics in March 2024 to hold legacy assets. This strategic move aligns with Serina's focus on advancing SER-252, their lead candidate for advanced Parkinson's disease, into clinical development. The company aims to explore their POZ Platform™ technology across multiple therapeutic applications, including small molecules, lipid nanoparticles (LNPs), and antibody-drug conjugates (ADCs).
Serina Therapeutics (NYSE American: SER) has announced the appointment of Karen J. Wilson to its Board of Directors. Wilson brings over 30 years of leadership experience in life sciences, currently serving on the boards of Connect Biopharma Holdings, Elicio Therapeutics, and LAVA Therapeutics.
Wilson previously held senior finance positions at Jazz Pharmaceuticals, including Senior Vice President of Finance and Principal Accounting Officer. Her prior experience includes senior finance roles at PDL BioPharma, ViroLogic, and Novare Surgical Systems, as well as consulting and auditing at Deloitte & Touche LLP. She is a Certified Public Accountant with a B.S. in Business from UC Berkeley.
The company also announced the departure of Steven Mintz from its Board of Directors, who helped guide Serina's transition from private to public company.
Serina Therapeutics (NYSE: SER) has announced a upcoming webinar presentation focused on continuous drug delivery solutions for Parkinson's disease. The event, titled 'Enabling Continuous Drug Delivery for Parkinson's Disease & Beyond,' will feature CEO Steven A. Ledger and is scheduled for December 18, 2024, at 8:30 AM Pacific/11:30 AM Eastern.
The presentation will address continuous dopaminergic stimulation (CDS), which has demonstrated effectiveness in reducing motor complications in advanced Parkinson's patients. The discussion will compare Serina's IND candidate's target product profile with current standard treatments in providing CDS. The event will be hosted by Tribe Public's Managing Member John F. Heerdink, Jr., and will include a Q&A session.
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