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SEELOS THERAPEUTICS INC - SEEL STOCK NEWS

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Seelos Therapeutics, Inc. (Nasdaq: SEEL) is a clinical-stage biopharmaceutical company committed to developing and commercializing novel therapeutic solutions for central nervous system (CNS) disorders and rare ailments. Based in New York, the company's primary focus is on innovative technologies aimed at treating conditions like major depressive disorder (MDD), post-traumatic stress disorder (PTSD), amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD), and more.

Key developments in Seelos' pipeline include:

  • SLS-002: An intranasal racemic ketamine targeting acute suicidal ideation and behavior in MDD and PTSD patients. This promising treatment has shown significant efficacy in Phase II trials, with plans for Phase III trials underway.
  • SLS-005: A protein stabilizer for treating Sanfilippo syndrome and ALS. Recent trials in collaboration with the HEALEY ALS Platform have highlighted its potential benefits, even though some endpoints were not statistically significant.
  • SLS-006: A partial dopamine agonist developed for PD patients, emphasizing symptom relief and improved quality of life.
  • Preclinical Programs: These include SLS-007, an anti-alpha-synuclein inhibitor for PD; SLS-008, targeting chronic inflammation in asthma and pediatric orphan indications; and SLS-004 and SLS-010 for PD and narcolepsy, respectively.

Seelos Therapeutics actively engages in various clinical trials and collaborations to advance its therapeutic offerings. The company recently announced public offerings and strategic financial maneuvers to support its robust pipeline, including offerings totaling approximately $10.65 million in gross proceeds. These funds are earmarked for advancing Seelos' clinical programs and general corporate purposes.

Committed to addressing unmet medical needs, Seelos Therapeutics is poised to make significant contributions to the biopharmaceutical landscape, with a keen focus on CNS disorders and rare diseases.

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Seelos Therapeutics (Nasdaq: SEEL) announced a $12 million sale of senior secured convertible notes and common stock, garnering $10 million in gross proceeds. The funding will support the development of its product candidates, including SLS-002, aimed at treating acute suicidal ideation. The notes feature a 24-month maturity with a 0% coupon and a conversion option at $1.60 per share, starting six months post-issuance. Lind Global Asset Management participated in this financing, emphasizing confidence in Seelos' clinical programs.

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Seelos Therapeutics, Inc. (Nasdaq: SEEL) announced participation in the 10th Annual LifeSci Partners Corporate Access Event from January 6-8 and 11-14, 2021. Chairman and CEO Raj Mehra, Ph.D. will hold one-on-one meetings via conference calls. The company focuses on developing therapies for central nervous system disorders and rare diseases, working on late-stage clinical assets targeting serious conditions like Acute Suicidal Ideation, amyotrophic lateral sclerosis, and more. For further details, visit Seelos Therapeutics.

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Seelos Therapeutics (Nasdaq: SEEL) announced the grant of a stock option for 50,000 shares to a new employee, under its 2019 Inducement Plan, compliant with Nasdaq Rule 5635(c)(4). The exercise price is set at $0.97, the closing share price on December 1, 2020. Vesting is structured over four years, with one-fourth vesting annually and the remainder monthly, contingent on continuous employment. This indicates the company's commitment to attracting talent in the competitive biopharmaceutical sector.

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Seelos Therapeutics has received Orphan Drug Designation (ODD) from the FDA for SLS-005, a treatment for amyotrophic lateral sclerosis (ALS). The drug is part of a Phase IIb/III clinical trial with plans to enroll 160 patients, assessing its impact on ALSFRS-R scores and other key metrics after 24 weeks. SLS-005 also holds ODD for conditions like Sanfilippo syndrome and spinsocerebellar ataxia type 3. The designation provides multiple development incentives, including tax credits for clinical testing.

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Seelos Therapeutics (Nasdaq: SEEL) will participate in the 3rd International Conference on Sanfilippo Syndrome on Nov. 13, 2020, at 2:30 PM CET. The session, led by CEO Raj Mehra, will focus on Trehalose (SLS-005), a potential treatment for MPS III. The conference aims to enhance collaboration between researchers, biotechnology firms, and families affected by rare diseases. The Sanfilippo Foundation Switzerland, which supports research into this syndrome, has raised over 8 million Swiss Francs for ten innovative research programs to date.

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Seelos Therapeutics, Inc. (Nasdaq: SEEL) announced the issuance of U.S. patent number 10815271 for SLS-007, a gene therapy targeting α-synuclein aggregates linked to Parkinson's disease. The patent covers the composition of matter and methods for reducing α-synuclein aggregation. The company is conducting an in vivo preclinical study to evaluate the pharmacokinetics and pharmacodynamics of SLS-007, with preliminary results expected in Q1 2021. CEO Raj Mehra emphasized the potential of SLS-007 to slow Parkinson's progression through a gene therapy approach.

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Seelos Therapeutics, Inc. (Nasdaq: SEEL) announced its participation in two investor conferences in November 2020. The events include the Jefferies Virtual Global Healthcare Conference from November 17-19 and the Benchmark Virtual Discovery One on One Investor Conference on November 18. Senior management, including Chairman and CEO Raj Mehra and Head of Research and Development Dr. Tim Whitaker, will host one-on-one meetings via conference calls. Seelos focuses on developing therapies for central nervous system disorders and rare diseases.

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Seelos Therapeutics (Nasdaq: SEEL) has signed a Sponsored Research Agreement with Duke University to study SLS-004, an innovative gene therapy for Parkinson's Disease (PD). The collaboration aims to use a mouse model to initiate proof-of-concept tests for the LV-dCas9-DNMT3A virus in preventing or delaying PD. This research builds on previous work focusing on a vector designed to modify α-synuclein protein expression. SLS-004 employs a novel epigenome-editing technique to effectively downregulate the SNCA gene, demonstrating potential as a new therapeutic strategy for PD.

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Seelos Therapeutics, Inc. (Nasdaq: SEEL) announced the issuance of a new patent (Japanese patent number 6722453) covering SLS-002, aimed at treating anxiety from phobic disorders such as Specific Phobia and Social Phobia. Additionally, the company received a Notice of Allowance for another patent application (Japanese patent number 2018-124196) that covers SLS-002's use in preventing anxiety before medical or dental procedures. These developments strengthen Seelos's intellectual property portfolio in the CNS disorder therapeutic area.

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Seelos Therapeutics (Nasdaq: SEEL) announced a Notice of Allowance from the USPTO for its patent application on trehalose (SLS-005). This patent covers methods to treat various neurodegenerative diseases, including spinocerebellar ataxia and frontotemporal dementia. Trehalose is known for its ability to cross the blood-brain barrier and activate autophagy, which may help reduce protein aggregation in cells. The allowance of this patent is a significant step for Seelos in its development of therapies targeting central nervous system disorders.

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FAQ

What is the current stock price of SEELOS THERAPEUTICS (SEEL)?

The current stock price of SEELOS THERAPEUTICS (SEEL) is $0.39 as of November 18, 2024.

What is the market cap of SEELOS THERAPEUTICS (SEEL)?

The market cap of SEELOS THERAPEUTICS (SEEL) is approximately 527.6K.

What does Seelos Therapeutics, Inc. do?

Seelos Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on developing therapeutics for central nervous system disorders and rare diseases.

What are the key products in Seelos Therapeutics' pipeline?

Key products include SLS-002 for acute suicidal ideation in MDD and PTSD, SLS-005 for ALS and Sanfilippo syndrome, and SLS-006 for Parkinson's disease.

What recent achievements has Seelos Therapeutics made?

Seelos has made significant strides in clinical trials for SLS-002 and SLS-005, and has announced various public offerings to fund ongoing and future projects.

How does SLS-002 work?

SLS-002 is an intranasal racemic ketamine designed to treat acute suicidal ideation and behavior in patients with major depressive disorder and PTSD.

What is the financial status of Seelos Therapeutics?

Seelos has recently raised approximately $10.65 million through public offerings to support its clinical programs and general corporate purposes.

Who are Seelos Therapeutics' key partners?

Seelos collaborates with various institutions, including the Sean M. Healey and AMG Center for ALS research, and engages with financial partners like Titan Partners Group and Roth Capital Partners.

What is SLS-005, and what does it treat?

SLS-005 is a protein stabilizer aimed at treating Sanfilippo syndrome and ALS. It works by stabilizing misfolded proteins and activating autophagy.

What is the status of SLS-005 in clinical trials?

SLS-005 has shown potential benefits in recent trials, particularly in a pre-specified subgroup of ALS patients, although it did not meet all primary and secondary endpoints.

How is Seelos Therapeutics funded?

Seelos is funded through public offerings and private placements, recently raising about $10.65 million to support its development programs and operations.

What are the future plans for Seelos Therapeutics?

Seelos plans to continue advancing its clinical trials, particularly for SLS-002 and SLS-005, and exploring potential partnerships to further its mission of addressing unmet medical needs in CNS disorders and rare diseases.

SEELOS THERAPEUTICS INC

Nasdaq:SEEL

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527.58k
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0.49%
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29.41%
Biotechnology
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