Sage Therapeutics, Inc - SAGE STOCK NEWS

Sage Therapeutics (NASDAQ: SAGE) has appointed Barry Greene as its new chief executive officer, effective immediately. Greene, previously president of Alnylam Pharmaceuticals, aims to leverage his expertise to accelerate Sage's growth in developing therapies for brain disorders. Jeff Jonas, former CEO, transitions to chief innovation officer to focus on pipeline expansion and neuroscience expertise. The board expressed confidence in Greene's leadership to drive commercialization and innovation at Sage, enhancing its pathways to address patient needs in mental health treatments.

Biogen and Sage Therapeutics have announced a collaboration to develop and commercialize zuranolone and SAGE-324, targeting major depressive disorder (MDD), postpartum depression (PPD), essential tremor, and other psychiatric and neurological disorders. The partnership includes a $1.525 billion cash agreement and potential milestone payments of $1.6 billion. Zuranolone, currently in Phase 3 trials, aims to offer rapid treatment for depression with sustained benefits. This collaboration could enhance both companies' strengths in neuroscience and address significant patient needs.

Sage Therapeutics reported Q3 2020 financial results, highlighting a revenue of $1.6 million from ZULRESSO, up from $1.5 million in Q3 2019. The company's cash position decreased to $671 million from $759 million. R&D expenses fell to $74.1 million versus $102.1 million in the previous year, primarily due to trial completions. A net loss of $105.7 million was reported, down from $180 million in 2019. Sage anticipates maintaining a cash balance of at least $550 million by year-end, supporting operations into 2022.

Sage Therapeutics, Inc. (NASDAQ: SAGE), a biopharmaceutical company dedicated to developing innovative therapies for brain disorders, will present at two key investor conferences in November 2020. The events include a fireside chat at the Stifel Virtual Healthcare Conference on November 16 at 8:40 am ET and a presentation at the Wolfe Research Virtual Healthcare Conference on November 19 at 4:05 pm ET. Investors can access live webcasts on Sage's investor page, with replays available for 30 days post-event.

Sage Therapeutics (NASDAQ: SAGE) announces that CEO Jeff Jonas, M.D. will undergo a scheduled surgical procedure today. The company expects him to make a full recovery and return to his role by December 2020. During his recovery, the Sage leadership team will oversee business operations, with support from the Board of Directors. Sage Therapeutics is focused on developing innovative therapies for brain disorders, aiming to improve brain health through its neurology, depression, and neuropsychiatry programs.

Sage Therapeutics announced a live webcast on November 5, 2020, at 8:30 a.m. ET to present its third quarter 2020 financial results and discuss recent business updates. The event will be accessible via the investor page on Sage's website. A replay of the webcast will be available shortly after the event and will remain archived for 30 days. Sage Therapeutics focuses on developing innovative therapies for brain disorders, aiming to enhance brain health through its depression and neurology programs.

Sage Therapeutics reported interim results from the Phase 3 SHORELINE Study evaluating zuranolone for major depressive disorder (MDD). The study indicated that zuranolone 30 mg was generally well-tolerated, with 71.6% of patients achieving a response after treatment. Approximately 70% of participants required only one or two treatment courses. Notably, 447 patients (61.7%) experienced adverse events, mostly mild or moderate. The study aims to provide insights into zuranolone's use as an as-needed treatment for MDD. Comprehensive results are expected in 2021.

Sage Therapeutics, Inc. (NASDAQ: SAGE) has appointed Barry Greene to its Board of Directors. Greene's extensive experience includes serving as President of Alnylam Pharmaceuticals and leading successful oncology strategies at Millennium Pharmaceuticals. His appointment aligns with Sage's commitment to innovation in brain health treatments. CEO Jeff Jonas emphasized Greene's leadership and operational excellence as vital to advancing the company's programs in depression and neurology. Greene expressed excitement about contributing to Sage’s mission of providing novel treatment options for central nervous system disorders.