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Sage Therapeutic - SAGE STOCK NEWS

Welcome to our dedicated page for Sage Therapeutic news (Ticker: SAGE), a resource for investors and traders seeking the latest updates and insights on Sage Therapeutic stock.

Overview

Sage Therapeutics is a clinical-stage biopharmaceutical company with a dedicated focus on advancing brain health medicines. With a primary commitment to tackling challenging CNS disorders, the company harnesses a deep scientific understanding to drive innovation in the treatment of depression, neurology, and neuropsychiatry. By leveraging robust clinical research and a pipeline of potentially transformative therapies, Sage Therapeutics aims to address unmet medical needs with a focus on safety, efficacy, and scientific excellence.

Business Model and Core Focus

The company operates within the biopharmaceutical sector, primarily generating value through the discovery and development of novel medicines targeted at central nervous system indications. Its business model revolves around translating groundbreaking neuroscience research into clinical-stage drug candidates that address both common and rare CNS disorders. Central to its strategy is the purposeful targeting of two critical receptor systems—GABA and NMDA—which have been linked to key pathways in mood regulation and cognitive function. This dual receptor strategy positions Sage Therapeutics as a focal point for innovative drug development, addressing patient populations that have been historically underserved.

Scientific Excellence and Research Initiatives

Sage Therapeutics distinguishes itself with a solid scientific foundation built on years of rigorous research and a portfolio of compounds generated from its robust chemistry platform. The company’s research efforts are characterized by:

  • Innovative Chemistry: The creation of new compounds that interact with CNS receptors, aiming to modulate brain activity in a therapeutic manner.
  • Targeted Pharmacology: Focus on GABA and NMDA receptors provides a strategic and scientific rationale for addressing disorders such as depression and seizure-related conditions.
  • Robust Clinical Foundations: Extensive preclinical activity and clinical development programs attest to the company’s commitment to advancing promising drug candidates through the necessary stages of evaluation.

Key Programs and Pipeline

Sage Therapeutics has structured its development pipeline with a mix of early and mid-stage clinical candidates targeting specific CNS disorders. Among its noteworthy programs are therapies aimed at addressing postpartum depression and rare epileptic conditions, as well as treatments targeting cognitive impairment. The company has developed treatment modalities that include both oral and injectable formulations, each designed to meet distinct clinical needs while adhering to rigorous safety and efficacy standards. This balanced pipeline not only underscores its scientific versatility but also reinforces its strategic focus on meaningful clinical outcomes.

Market Position and Competitive Landscape

Positioned within a highly competitive sphere of neuroscience-focused biopharma companies, Sage Therapeutics harnesses its specialized research and a diverse drug portfolio to effectively address complex CNS disorders. The company’s approach, which integrates strong basic science with advanced clinical development, enables it to navigate an industry marked by stringent regulatory standards and competitive innovation. Sage Therapeutics differentiates itself by focusing on creating medicines that fulfill critical therapeutic gaps, particularly in conditions where conventional treatments have been limited or ineffective.

Expertise, Partnerships, and Collaborative Approach

The company is supported by a world-class team comprising founders, advisors, research and development leaders, and industry experts. This collective expertise fosters an environment of continuous innovation and strategic collaboration. By working with academic institutions, research organizations, and clinical experts, Sage Therapeutics not only accelerates the development of its therapeutic candidates but also reinforces its credibility through diverse external partnerships. This collaborative framework exemplifies the company’s commitment to scientific rigor and transparency, which are crucial in the evolving fields of neuroscience and biopharmaceutical innovation.

Commitment to Science and Innovation

At its core, Sage Therapeutics is driven by the mission to improve life for patients suffering from serious CNS disorders through pioneering drug development. Its integrated approach combines cutting-edge science, a robust pipeline of clinical candidates, and strategic partnerships to generate potential therapies with meaningful clinical impact. The company’s careful navigation of the research and clinical landscape—marked by in-depth scientific inquiry and adherence to regulatory standards—shows a commitment to both innovation and the highest levels of medical and research excellence.

Conclusion

In summary, Sage Therapeutics represents a focused and scientifically driven approach to addressing central nervous system disorders. With its deep research foundation, multi-faceted clinical programs, and a strategic vision anchored in targeting GABA and NMDA receptors, the company has positioned itself as an expert in the biotech and pharmaceutical arena. Its comprehensive and collaborative methodology serves as a testament to the critical role of rigorous scientific inquiry in developing meaningful, life-improving therapies for some of the most challenging brain health conditions.

Rhea-AI Summary

Sage Therapeutics (NASDAQ: SAGE) will host a webcast on February 24, 2021, at 8:00 a.m. ET to announce its fourth quarter and full year 2020 financial results, alongside recent business updates. The broadcast will be accessible through the investor page of Sage's website, with a replay available post-event for 30 days. Sage Therapeutics focuses on innovative therapies for brain disorders, with an aim to revolutionize treatment approaches in depression, neurology, and neuropsychiatry.

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Sage Therapeutics (NASDAQ: SAGE) announced its participation in the 39th Annual J.P. Morgan Healthcare Conference, where CEO Barry Greene will present the company's progress and plans for 2021. Key highlights include the advancement of SAGE-718, SAGE-689, and SAGE-904 into further development phases. The company recently secured $1.525 billion from a collaboration with Biogen to develop zuranolone for major depressive disorder and other conditions, bolstering its cash position to $2.1 billion. Sage anticipates several critical data readouts from its clinical programs this year.

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Sage Therapeutics (NASDAQ: SAGE) has announced its participation in the 39th Annual J.P. Morgan Healthcare Conference, scheduled for January 12, 2021, at 10:50 a.m. ET. The event will be live-streamed on Sage's investor page, with a replay available for 30 days post-conference. Sage focuses on developing innovative therapies aimed at improving brain health for individuals facing severe brain disorders, including depression and neuropsychiatric conditions. The company aims to transform treatment approaches and enhance patient outcomes.

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Sage Therapeutics (NASDAQ: SAGE) has appointed Barry Greene as its new chief executive officer, effective immediately. Greene, previously president of Alnylam Pharmaceuticals, aims to leverage his expertise to accelerate Sage's growth in developing therapies for brain disorders. Jeff Jonas, former CEO, transitions to chief innovation officer to focus on pipeline expansion and neuroscience expertise. The board expressed confidence in Greene's leadership to drive commercialization and innovation at Sage, enhancing its pathways to address patient needs in mental health treatments.

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Biogen and Sage Therapeutics have announced a collaboration to develop and commercialize zuranolone and SAGE-324, targeting major depressive disorder (MDD), postpartum depression (PPD), essential tremor, and other psychiatric and neurological disorders. The partnership includes a $1.525 billion cash agreement and potential milestone payments of $1.6 billion. Zuranolone, currently in Phase 3 trials, aims to offer rapid treatment for depression with sustained benefits. This collaboration could enhance both companies' strengths in neuroscience and address significant patient needs.

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Sage Therapeutics reported Q3 2020 financial results, highlighting a revenue of $1.6 million from ZULRESSO, up from $1.5 million in Q3 2019. The company's cash position decreased to $671 million from $759 million. R&D expenses fell to $74.1 million versus $102.1 million in the previous year, primarily due to trial completions. A net loss of $105.7 million was reported, down from $180 million in 2019. Sage anticipates maintaining a cash balance of at least $550 million by year-end, supporting operations into 2022.

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Sage Therapeutics, Inc. (NASDAQ: SAGE), a biopharmaceutical company dedicated to developing innovative therapies for brain disorders, will present at two key investor conferences in November 2020. The events include a fireside chat at the Stifel Virtual Healthcare Conference on November 16 at 8:40 am ET and a presentation at the Wolfe Research Virtual Healthcare Conference on November 19 at 4:05 pm ET. Investors can access live webcasts on Sage's investor page, with replays available for 30 days post-event.

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Sage Therapeutics (NASDAQ: SAGE) announces that CEO Jeff Jonas, M.D. will undergo a scheduled surgical procedure today. The company expects him to make a full recovery and return to his role by December 2020. During his recovery, the Sage leadership team will oversee business operations, with support from the Board of Directors. Sage Therapeutics is focused on developing innovative therapies for brain disorders, aiming to improve brain health through its neurology, depression, and neuropsychiatry programs.

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Sage Therapeutics announced a live webcast on November 5, 2020, at 8:30 a.m. ET to present its third quarter 2020 financial results and discuss recent business updates. The event will be accessible via the investor page on Sage's website. A replay of the webcast will be available shortly after the event and will remain archived for 30 days. Sage Therapeutics focuses on developing innovative therapies for brain disorders, aiming to enhance brain health through its depression and neurology programs.

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FAQ

What is the current stock price of Sage Therapeutic (SAGE)?

The current stock price of Sage Therapeutic (SAGE) is $6.39 as of April 8, 2025.

What is the market cap of Sage Therapeutic (SAGE)?

The market cap of Sage Therapeutic (SAGE) is approximately 421.1M.

What is the primary focus of Sage Therapeutics?

Sage Therapeutics is dedicated to developing innovative medicines to treat central nervous system disorders, focusing on conditions such as depression, neurology, and neuropsychiatry.

Which receptor systems are targeted by the company?

The company strategically targets the GABA and NMDA receptor systems, which are crucial in the modulation of brain function and linked to various CNS disorders.

How does Sage Therapeutics drive its drug development?

Sage Therapeutics leverages a robust chemistry platform and extensive clinical research, working with world-class experts and strategic partnerships to move promising drug candidates through clinical development.

What therapeutic areas are included in the company’s pipeline?

The pipeline spans several therapeutic areas, including treatments for postpartum depression, epilepsy-related conditions, and cognitive impairments, reflecting its broad neuroscience focus.

How does the company position itself within the competitive landscape?

By integrating rigorous scientific research with advanced clinical development, Sage Therapeutics differentiates itself as a focused biopharmaceutical innovator addressing critical gaps in CNS disorder treatments.

What role do strategic partnerships play at Sage Therapeutics?

Collaborative efforts with academic institutions, clinical experts, and research organizations help enhance the company’s research capabilities and accelerate the development of its therapeutic candidates.

Can you describe the company’s approach to research and development?

The approach is anchored in deep scientific inquiry and a commitment to innovation, combining robust preclinical and clinical research to create therapies that address major unmet medical needs in brain health.

How does Sage Therapeutics ensure scientific credibility?

The company builds its credibility through a world-class team of experts, rigorous clinical studies, and a sustained focus on targeting key CNS receptor systems, demonstrating both expertise and strategic precision in drug development.
Sage Therapeutic

Nasdaq:SAGE

SAGE Rankings

SAGE Stock Data

421.14M
54.11M
11.94%
79.96%
6.37%
Biotechnology
Pharmaceutical Preparations
Link
United States
CAMBRIDGE