Welcome to our dedicated page for Recursion Pharmaceuticals news (Ticker: RXRX), a resource for investors and traders seeking the latest updates and insights on Recursion Pharmaceuticals stock.
Recursion Pharmaceuticals, Inc. (NASDAQ: RXRX) is a clinical-stage biotechnology company revolutionizing the field of drug discovery. By integrating technological innovations across biology, chemistry, automation, data science, and engineering, Recursion aims to decode biology and industrialize the drug discovery process.
Founded with a vision to radically improve patient lives, Recursion has developed a powerful drug discovery platform capable of conducting millions of rapid, automated experiments. This platform leverages the Recursion Operating System (OS), a sophisticated data and machine learning infrastructure, to accelerate the discovery of therapeutics, especially for rare genetic diseases.
Recent achievements include pioneering the use of machine learning in predicting protein-ligand interactions and partnering with major pharmaceutical companies like Bayer and Enamine. These collaborations have significantly enhanced Recursion's capabilities in chemical space exploration and drug discovery.
Financially, Recursion is robust, constantly expanding its dataset and computational resources, including operating one of the world's most powerful supercomputers, BioHive-2. This supercomputer, equipped with NVIDIA DGX H100 systems, significantly enhances their ability to train AI models and accelerate drug discovery.
Headquartered in Salt Lake City and with offices in Toronto, Montréal, and the San Francisco Bay Area, Recursion is a founding member of BioHive, the Utah life sciences industry collective. The company's horizontal business model focuses on discovery, allowing for cost-efficient operations by spreading risks across various therapeutic opportunities.
Significant News:
- Partnership with Enamine: Recursion announced a partnership with Enamine to leverage its MatchMaker tool for enriched screening libraries.
- Agreement with Bayer: Recursion in-licensed a novel molecule for treating fibrotic diseases from its collaboration with Bayer.
- Launch of LOWE: Demonstrated LOWE, an LLM-based software for drug discovery tasks, in collaboration with NVIDIA.
- London Expansion: Opened a new office in London and appointed Michael Bronstein as a Scientific Advisor.
- First Quarter 2024 Financial Results: Reported significant progress and upcoming value catalysts in drug discovery and technology advancements.
- BioHive-2 Supercomputer: Launched BioHive-2, a top-tier supercomputer, to enhance AI model training and drug discovery processes.
- Nature Genetics Publication: Published findings on proximity bias in CRISPR-Cas9 editing and proposed a debiasing algorithm.
For more information, visit Recursion Pharmaceuticals or follow their updates on Twitter and LinkedIn.
Recursion (RXRX) and Exscientia (EXAI) shareholders have approved their proposed business combination, with the transaction expected to close on November 20, 2024. The combined company will integrate Recursion's biological and chemical exploration capabilities with Exscientia's molecular design and automated chemistry synthesis expertise to enhance drug discovery processes. An update call is scheduled for November 20, 2024, at 7:30 a.m. ET. The final voting results will be disclosed in regulatory filings with the SEC.
Recursion (NASDAQ: RXRX) has released OpenPhenom-S/16, a publicly available foundation model in Google Cloud's Vertex AI Model Garden. The model, trained on over three million microscopy images from public datasets, sets a new performance standard for microscopy data analysis, outperforming traditional methods like CellProfiler. The model enables automated classification of cellular structures and pattern detection without requiring additional tuning. Alongside the model, Recursion is releasing the RxRx3-core dataset, which includes labeled images of 735 genetic knockouts and 1,674 small-molecule perturbations, designed to advance research in drug mechanism mapping.
Recursion (RXRX) reported Q3 2024 financial results with revenue of $26.1 million, up from $10.5 million in Q3 2023. The company achieved multiple clinical milestones, including positive Phase 2 CCM trial data and FDA clearance for a Phase 1/2 trial in biomarker-enriched tumors. Roche-Genentech optioned their first neuroscience phenomap for $30 million. The company expanded its collaboration with Google Cloud for drug discovery platform support. Q3 net loss was $95.8 million with cash position of $427.6 million. The pending business combination with Exscientia is expected to close on November 20, 2024.
Recursion (NASDAQ: RXRX) announced it will release its Q3 2024 business updates and financial results on November 6, 2024, after market close. The company will not hold its regular earnings call for Q3. Instead, Recursion plans to host an update call on November 20, 2024, following the expected completion of its proposed business combination with Exscientia. The call will be streamed live on Recursion's social media platforms, including X (formerly Twitter), LinkedIn, and YouTube, with opportunities for Q&A.
Recursion (NASDAQ: RXRX) has dosed the first patient in its Phase 2 clinical trial of REC-3964, an oral, non-antibiotic small molecule designed for recurrent Clostridioides difficile (C. diff) infection. The novel treatment selectively inhibits the glucosyltransferase activity of toxin B produced by C. diff, aiming to prevent recurrence while sparing the gut microbiome. C. diff infections cause significant morbidity and mortality, with up to 175,000 recurrent cases annually in the U.S. and high recurrence rates post-antibiotic treatment. Preclinical studies showed REC-3964's superiority over bezlotoxumab, and Phase 1 trials demonstrated its safety and tolerability. The Phase 2 ALDER trial will enroll around 80 participants across the U.S. and Europe to assess safety, tolerability, pharmacokinetics, and efficacy.
Recursion (NASDAQ: RXRX) has received FDA clearance for an Investigational New Drug (IND) application for REC-1245, a potential first-in-class RBM39 degrader targeting biomarker-enriched solid tumors and lymphoma. This program, developed using Recursion's AI-enabled active learning modules, progressed from target identification to IND-enabling studies in under 18 months.
The company plans to initiate a Phase 1/2 clinical trial in Q4 2024, evaluating REC-1245 in a biomarker-enriched patient population. Recursion identified RBM39's novel regulatory role associated with CDK12 using its maps of biology. The company estimates the initially addressable population for this potential therapeutic to be over 100,000 patients in the US and EU5.
Preclinical data suggest that RBM39 degradation induces splicing defects, downregulating DNA Damage Response networks and cell cycle checkpoints. The upcoming clinical trial will assess the safety, tolerability, pharmacokinetics, pharmacodynamics, and potential monotherapy efficacy of REC-1245.
Recursion (NASDAQ: RXRX) announced positive top-line results from its SYCAMORE trial, a Phase 2 study of REC-994 for symptomatic Cerebral Cavernous Malformation (CCM). The trial met its primary endpoint of safety and tolerability, with similar profiles across placebo and both 200mg and 400mg dosage arms. Encouraging trends in MRI-based secondary efficacy endpoints were observed, particularly at the highest dose (400mg), showing reduced lesion volume and hemosiderin ring size compared to placebo.
The company plans to advance REC-994's development for potential CCM treatment in subsequent studies. A meeting with the FDA is anticipated to discuss plans for an additional clinical study. Recursion aims to present the data at a future medical conference and submit it for peer-reviewed publication.
Recursion (Nasdaq: RXRX) issued a correction to its earlier press release regarding its second quarter 2024 financial results. The company clarified that its earnings call took place earlier in the morning on Aug 8, 2024 at 8:30 am Eastern Time / 6:30 am Mountain Time, rather than being scheduled for later in the afternoon as previously stated. The live stream of the call was broadcast from Recursion's X (formerly Twitter), LinkedIn, and YouTube accounts, providing opportunities for questions. No other changes were made to the original release.
Recursion (RXRX) and Exscientia (EXAI) have announced a definitive agreement to merge, creating a global technology-enabled drug discovery leader. The combination aims to leverage Recursion's biology exploration and Exscientia's precision chemistry design capabilities. Key highlights include:
- Expected annual synergies of approximately $100 million
- Combined pipeline with 10 clinical readouts expected in the next 18 months
- Potential for $200 million in milestone payments over 24 months
- Well-capitalized with $850 million in cash and equivalents
- Exscientia shareholders to receive 0.7729 shares of Recursion for each share owned
The merger is expected to close by early 2025, subject to shareholder and regulatory approvals. The combined company will retain the Recursion name and be headquartered in Salt Lake City, Utah.
Recursion (RXRX) announced a definitive agreement to combine with Exscientia, enhancing its drug discovery capabilities. Key highlights include:
1. 7 clinical trial readouts expected for Recursion and 10 collectively with Exscientia over the next 18 months.
2. First neuroscience phenomap optioned by Roche and Genentech, triggering a $30 million payment.
3. Combined deals have potential for over $20 billion in milestones plus royalties.
4. Q2 2024 financial results: Revenue of $14.4 million, up from $11.0 million in Q2 2023. Net loss of $97.5 million, compared to $76.7 million in Q2 2023.
5. Cash position of $474.3 million as of June 30, 2024.
6. Completed a follow-on public offering, raising net proceeds of $216.4 million.
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