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Resverlogix Corp. (RVXCF) is a Calgary based late-stage biotechnology company and the world leader in epigenetics, founded in 2001. The company's main focus is on developing first-in-class therapies for patients with chronic diseases. Resverlogix is known for its lead epigenetic candidate, apabetalone (RVX-208), a BD2 selective BET inhibitor with an epigenetic mechanism of action. Apabetalone has shown promising results in multiple diseases, including cardiovascular disease, diabetes, post-COVID-19 conditions, and more. Resverlogix has collaborated with EVERSANA™ to support the rapid commercialization of apabetalone in Canada and the United States.
Resverlogix Corp. (TSX: RVX) presented at the European Society of Cardiology (ESC) Congress 2024, highlighting apabetalone's potential cardioprotective benefits. Key points include:
1. Apabetalone reduced MACE and heart failure hospitalization hazard by 63% (p=0.0002) in patients taking next-generation glucose-lowering drugs.
2. Independent researchers presented data on apabetalone's benefits for vascular dysfunction, heart failure, cellular aging, and pulmonary arterial hypertension.
3. The company positions apabetalone as a drug with potential benefits across various metabolic diseases, including cardiovascular disease, chronic kidney disease, inflammation, and diabetes.
4. Resverlogix plans to demonstrate apabetalone's efficacy in combination with SGLT2 inhibitors in the upcoming BETonMACE2 trial.
Resverlogix Corp. (TSX: RVX) held its Annual & Special Meeting of Shareholders on July 31, 2024, in Calgary, Alberta. Shareholders elected four Board members and approved all resolutions outlined in the Notice of Meeting and Management Information Circular. The voting results showed strong support for all directors, with approval rates ranging from 95.11% to 95.91%.
Additionally, Resverlogix announced the closing of a two-year extension of its US$6.0 million secured debenture with Shenzhen Hepalink Pharmaceutical Group Co., This extension provides the company with continued financial stability. The Information Circular is available on SEDAR and the Resverlogix website, and a webcast archive of the executive presentation is accessible online.
Resverlogix Corp. (TSX: RVX) has announced a two-year extension of its US$6.0 million secured convertible debenture with Shenzhen Hepalink Pharmaceutical Group Co., The maturity date has been extended to May 13, 2026. Key changes include:
1. Elimination of Hepalink's conversion privileges
2. Increase in interest rate from 12% to 18% per annum, effective May 14, 2024
3. Additional reporting requirements for Resverlogix
4. Continuation of normal business operations
The amendment is subject to Toronto Stock Exchange and shareholder approval. Shareholders will vote on the amendments at Resverlogix's annual and special meeting on July 31, 2024. Hepalink has agreed to forbear from enforcing the debenture, contingent on shareholder approval.
Resverlogix has rescheduled its Annual and Special Meeting of Shareholders to July 31, 2024, at 1:00 PM MT, from its original date of June 27, 2024. Shareholders will receive a Notice of Meeting and Management Information Circular detailing the matters to be discussed. These documents will also be available on SEDAR+ at www.sedarplus.ca. Following the formal business proceedings, Resverlogix will present a corporate update.
Resverlogix Corp. (TSX: RVX) announced a two-year extension of its US$6.0 million secured convertible debenture with Shenzhen Hepalink Pharmaceutical Group. The new maturity date is May 13, 2026.
Along with the extension, Hepalink's conversion privileges have been eliminated, and the interest rate has increased from 12% to 18% per annum, starting May 14, 2024. The changes are subject to execution of definitive transaction documents, customary closing conditions, and Toronto Stock Exchange approval.
CEO Donald McCaffrey expressed appreciation for Hepalink's continued support.
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