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TransCode Therapeutics, Inc. - RNAZ STOCK NEWS

Welcome to our dedicated page for TransCode Therapeutics news (Ticker: RNAZ), a resource for investors and traders seeking the latest updates and insights on TransCode Therapeutics stock.

TransCode Therapeutics, Inc. (NASDAQ: RNAZ) is a Boston-based clinical-stage biopharmaceutical company dedicated to combating metastatic disease through the discovery, development, and commercialization of novel microRNA (miRNA) therapeutics. The company's pioneering work centers around its proprietary TTX nanoparticle platform, designed to effectively deliver RNA-based therapies to target and treat various cancers.

The lead therapeutic candidate of TransCode Therapeutics, TTX-MC138, focuses on metastatic tumors that overexpress microRNA-10b, a well-known biomarker associated with metastasis. This candidate is currently undergoing rigorous clinical trials, with initial results indicating promising accumulation of the therapy in metastatic lesions.

The company also boasts a diverse pipeline of RNA therapeutic candidates, including TTX-siPDL1 and TTX-RIGA, aimed at overcoming the delivery challenges of RNA therapies and addressing novel genetic targets relevant to different cancer types. TransCode is actively engaged in expanding its research collaborations, as highlighted by its project combining the TTX platform with Debiopharm’s drug delivery technologies.

However, TransCode faces noteworthy financial and regulatory challenges. Recent communications reveal that the company is addressing compliance issues with Nasdaq listing requirements and the potential need for a reverse stock split to maintain its listing status. Despite these hurdles, TransCode remains committed to advancing its research and development efforts, securing strategic partnerships, and raising sufficient capital to drive its innovative pipeline forward.

TransCode’s vision extends beyond treating metastatic cancer; they aim to revolutionize cancer therapy by creating highly selective treatments that trigger the immune response against tumors while sparing healthy tissues. This approach is exemplified by their tumor-selective RIG-I agonists currently in development.

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TransCode Therapeutics announces dosing of first subject in Phase 0 trial for TTX-MC138
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TransCode Therapeutics reports Q2 financial results and recent business progress. They have advanced their therapeutic programs, dosed their first patients in a Phase 0 clinical trial, closed a funding round of $7M, and expanded their delivery platform. They expect to achieve major milestones in the coming months.
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TransCode Therapeutics, Inc. announced positive results with its lead therapeutic candidate, TTX-MC138, in non-human primates. The study showed that TTX-MC138 effectively engaged its target, miRNA-10b, and demonstrated favorable pharmacokinetics and tissue distribution. The therapeutic showed lasting activity and significantly inhibited miRNA-10b, known to be a driver of metastatic progression in cancers. Data from the study were incorporated into a DMPK model, predicting long circulation and tissue distribution in humans. TTX-MC138 has shown complete regression of metastatic disease in mouse models and preliminary efficacy in a case study of feline mammary carcinoma.
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Stonegate Healthcare Partners has released a thematic report on RNA Therapeutics, focusing on the potential of RNA therapeutics and companies leveraging RNAi technologies. The report covers over 30 companies, including Alnylam, Ionis, Laronde, TME Pharma, and Transcode Therapeutics (NASDAQ: RNAZ). It highlights innovative and undervalued companies in the field of RNA therapeutics.
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TransCode Therapeutics announces progress in the development of TTX-MC138, a lead therapeutic candidate for treating metastatic cancer. The company has received FDA approval for a first-in-human clinical trial and IRB approval to enroll patients in a Phase 0 trial. TransCode's proprietary therapeutic delivery platform shows potential to address the unmet needs of oncology patients. The company has also achieved positive results with other therapeutic candidates and established strategic partnerships. TransCode has received Orphan Drug Designation for TTX-siPDL1 and plans to conduct additional studies for other TTX-based candidates in orphan disease indications. The company aims to advance its pipeline and become a leading oncology company.
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TransCode Therapeutics, Inc. announces pricing of public offering of common stock and warrants
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FAQ

What is the current stock price of TransCode Therapeutics (RNAZ)?

The current stock price of TransCode Therapeutics (RNAZ) is $0.38 as of November 21, 2024.

What is the market cap of TransCode Therapeutics (RNAZ)?

The market cap of TransCode Therapeutics (RNAZ) is approximately 6.4M.

What does TransCode Therapeutics, Inc. specialize in?

TransCode Therapeutics specializes in developing RNA-based therapeutic candidates targeting metastatic diseases using its proprietary TTX nanoparticle platform.

What is TTX-MC138?

TTX-MC138 is TransCode's lead therapeutic candidate focused on treating metastatic tumors that overexpress microRNA-10b, a marker associated with metastasis.

What are the challenges TransCode Therapeutics is facing?

TransCode is facing challenges related to meeting Nasdaq listing requirements and may need to consider a reverse stock split to maintain its listing status.

What is the significance of the TTX nanoparticle platform?

The TTX nanoparticle platform enables the precise delivery of RNA therapeutics, overcoming delivery challenges and potentially unlocking treatments for various cancers.

What recent project involves TransCode’s TTX platform?

A recent project involves testing the combination of TransCode’s TTX delivery platform with Debiopharm’s drug delivery technologies.

What is the clinical status of TTX-MC138?

TTX-MC138 is currently in clinical trials, with initial data indicating effective accumulation in metastatic lesions.

How does TransCode aim to innovate cancer therapy?

TransCode aims to innovate cancer therapy by developing treatments that selectively trigger the immune system to attack tumors while sparing healthy tissues.

What are some other RNA therapeutic candidates in TransCode’s pipeline?

Other candidates include TTX-siPDL1 and TTX-RIGA, designed to address novel genetic targets relevant to various types of cancer.

Who can I contact for more information about TransCode Therapeutics?

For more information, you can contact Tania Montgomery-Hammon, VP of Business Development, at tania.montgomery@transcodetherapeutics.com.

What are TransCode’s goals for 2024?

TransCode aims to strengthen its organization, raise capital, expand strategic partnerships, and advance both its clinical and preclinical portfolios.

TransCode Therapeutics, Inc.

Nasdaq:RNAZ

RNAZ Rankings

RNAZ Stock Data

6.42M
17.26M
0.01%
1.99%
4.31%
Biotechnology
Pharmaceutical Preparations
Link
United States of America
BOSTON