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TransCode Therapeutics, Inc. - RNAZ STOCK NEWS

Welcome to our dedicated page for TransCode Therapeutics news (Ticker: RNAZ), a resource for investors and traders seeking the latest updates and insights on TransCode Therapeutics stock.

TransCode Therapeutics, Inc. (NASDAQ: RNAZ) is a Boston-based clinical-stage biopharmaceutical company dedicated to combating metastatic disease through the discovery, development, and commercialization of novel microRNA (miRNA) therapeutics. The company's pioneering work centers around its proprietary TTX nanoparticle platform, designed to effectively deliver RNA-based therapies to target and treat various cancers.

The lead therapeutic candidate of TransCode Therapeutics, TTX-MC138, focuses on metastatic tumors that overexpress microRNA-10b, a well-known biomarker associated with metastasis. This candidate is currently undergoing rigorous clinical trials, with initial results indicating promising accumulation of the therapy in metastatic lesions.

The company also boasts a diverse pipeline of RNA therapeutic candidates, including TTX-siPDL1 and TTX-RIGA, aimed at overcoming the delivery challenges of RNA therapies and addressing novel genetic targets relevant to different cancer types. TransCode is actively engaged in expanding its research collaborations, as highlighted by its project combining the TTX platform with Debiopharm’s drug delivery technologies.

However, TransCode faces noteworthy financial and regulatory challenges. Recent communications reveal that the company is addressing compliance issues with Nasdaq listing requirements and the potential need for a reverse stock split to maintain its listing status. Despite these hurdles, TransCode remains committed to advancing its research and development efforts, securing strategic partnerships, and raising sufficient capital to drive its innovative pipeline forward.

TransCode’s vision extends beyond treating metastatic cancer; they aim to revolutionize cancer therapy by creating highly selective treatments that trigger the immune response against tumors while sparing healthy tissues. This approach is exemplified by their tumor-selective RIG-I agonists currently in development.

News

TransCode Therapeutics Reports 2023 Results; Provides Business Update

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TransCode Therapeutics, Inc. (NASDAQ: RNAZ) reported financial results for 2023 and key business developments. The company advanced its lead therapeutic candidate, TTX-MC138, into clinical trials, raised over $25 million in equity financing, and signed strategic collaborations. Positive preliminary clinical results were reported, and key partnerships were formed to develop RNA therapeutics for cancer treatment. The company aims to initiate a Phase 1 clinical trial for TTX-MC138 in mid-2024, with a focus on advancing research and expanding collaborations in 2024.
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TransCode Therapeutics Announces Appointment of Daniel Vlock, M.D., as Chief Medical Officer

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TransCode Therapeutics, Inc. appoints Dr. Daniel Vlock, a seasoned medical oncologist with over 25 years of industry experience, as Chief Medical Officer. Dr. Vlock's extensive background includes pivotal roles in managing clinical trials and successful product developments in oncology, infectious diseases, and more.
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TransCode Therapeutics and Akribion Genomics Report Progress Developing CRISPR-Derived Technology for Cancer Treatment

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TransCode Therapeutics (NASDAQ: RNAZ) reports positive proof-of-concept studies in collaboration with Akribion Genomics for a potential cancer treatment involving CRISPR technology. The partnership aims to combine Akribion's G-dase E with TransCode's TTX delivery platform to target cancer cells effectively.
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TransCode Therapeutics To Present At 2024 RNA Leaders Europe Congress

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TransCode Therapeutics, Inc. (NASDAQ: RNAZ) announces Chief Scientific Officer Dr. Zdravka Medarova to present at RNA Leaders Europe Congress. The presentation will focus on TTX-MC138, a potential therapy for metastatic cancer, detailing preclinical and early clinical trial data.
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TransCode Therapeutics Reports Publication of United States Patent Application Covering TransCode’s RIG-I Agonist Immunotherapeutic

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TransCode Therapeutics, Inc. (NASDAQ: RNAZ) announced the publication of a US Patent Application focusing on innovative cancer therapy using RNA therapeutics. The application targets RIG-I-like receptors to activate the immune system against cancer cells, potentially revolutionizing cancer treatment.
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Nasdaq Determines TransCode Therapeutics Compliance with Minimum Stockholders’ Equity Requirement and Continued Listing on The Nasdaq Stock Market

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TransCode Therapeutics, Inc. (Nasdaq: RNAZ) has received notice from the Nasdaq Stock Market LLC that it has regained compliance with the minimum stockholders' equity requirement under Nasdaq Listing Rule 5550(b)(1) for continued listing. The company will be subject to a mandatory panel monitor through January 26, 2025. Additionally, the company was notified that it was not in compliance with the minimum bid price rule, and it must regain compliance by May 6, 2024, or be eligible for an additional 180 calendar day compliance period.
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TransCode Therapeutics and Debiopharm Announce Collaboration to Develop Targeted Nucleic Acid Therapeutics for Cancer

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TransCode Therapeutics, Inc. (NASDAQ: RNAZ) announces a co-research agreement with Debiopharm to explore combining TransCode’s proprietary TTX delivery platform with Debiopharm’s expertise in targeted drug delivery to co-develop targeted nucleic acid therapeutics for cancer. The collaboration aims to test the development of new targeted nucleic acid delivery modalities, with the potential to revolutionize cancer research and treatment. TransCode's lead therapeutic candidate, TTX-MC138, designed to use antisense technology to treat metastatic cancer, is being evaluated in an early-stage clinical trial.
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TransCode Therapeutics Announces Closing of $7.25 Million Public Offering

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TransCode Therapeutics, Inc. (RNAZ) has closed a public offering, raising $7.25 million in gross proceeds. The offering included 5,942,623 shares of common stock and warrants to purchase up to 11,885,246 shares at a price of $1.22 per share. The company plans to use the net proceeds for product development activities, including clinical trials with its lead therapeutic candidate, TTX-MC138, and for general corporate purposes.
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TransCode Therapeutics Announces Pricing of $7.25 Million Public Offering

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TransCode Therapeutics, Inc. (RNAZ) announces the pricing of a public offering of 5,942,623 shares of common stock and warrants to purchase up to 11,885,246 shares at a combined public offering price of $1.22 per share. The warrants will have an exercise price of $1.22 per share and will expire three and one-half years from the date of issuance.
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TransCode Therapeutics Reports Further Restructuring to Reduce Expenses and Increased Focus on Planned Phase 1 Clinical Trial, Retirement of CEO

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TransCode Therapeutics, Inc. (RNAZ) reported further steps in its restructuring to reduce expenditures and focus on its lead therapeutic candidate. The CEO announced his retirement, and the CFO will become interim CEO. The Chief Technology Officer has been promoted to Chief Scientific Officer, and the Chairman of the Board of Directors will assume the position of Executive Chairman.
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FAQ

What is the current stock price of TransCode Therapeutics (RNAZ)?

The current stock price of TransCode Therapeutics (RNAZ) is $3.28 as of January 10, 2025.

What is the market cap of TransCode Therapeutics (RNAZ)?

The market cap of TransCode Therapeutics (RNAZ) is approximately 2.3M.

What does TransCode Therapeutics, Inc. specialize in?

TransCode Therapeutics specializes in developing RNA-based therapeutic candidates targeting metastatic diseases using its proprietary TTX nanoparticle platform.

What is TTX-MC138?

TTX-MC138 is TransCode's lead therapeutic candidate focused on treating metastatic tumors that overexpress microRNA-10b, a marker associated with metastasis.

What are the challenges TransCode Therapeutics is facing?

TransCode is facing challenges related to meeting Nasdaq listing requirements and may need to consider a reverse stock split to maintain its listing status.

What is the significance of the TTX nanoparticle platform?

The TTX nanoparticle platform enables the precise delivery of RNA therapeutics, overcoming delivery challenges and potentially unlocking treatments for various cancers.

What recent project involves TransCode’s TTX platform?

A recent project involves testing the combination of TransCode’s TTX delivery platform with Debiopharm’s drug delivery technologies.

What is the clinical status of TTX-MC138?

TTX-MC138 is currently in clinical trials, with initial data indicating effective accumulation in metastatic lesions.

How does TransCode aim to innovate cancer therapy?

TransCode aims to innovate cancer therapy by developing treatments that selectively trigger the immune system to attack tumors while sparing healthy tissues.

What are some other RNA therapeutic candidates in TransCode’s pipeline?

Other candidates include TTX-siPDL1 and TTX-RIGA, designed to address novel genetic targets relevant to various types of cancer.

Who can I contact for more information about TransCode Therapeutics?

For more information, you can contact Tania Montgomery-Hammon, VP of Business Development, at tania.montgomery@transcodetherapeutics.com.

What are TransCode’s goals for 2024?

TransCode aims to strengthen its organization, raise capital, expand strategic partnerships, and advance both its clinical and preclinical portfolios.
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TransCode Therapeutics, Inc.

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Biotechnology
Pharmaceutical Preparations
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United States of America
BOSTON