RELIEF THERAPEUTICS S/ADR - RLFTY STOCK NEWS

Relief Therapeutics announced that its collaboration partner Acer Therapeutics received a new patent (11,202,767) for ACER-001, covering methods of use related to this treatment for Urea Cycle Disorders (UCDs) and Maple Syrup Urine Disease (MSUD). This adds to a previous patent (11,154,521) for the pharmaceutical composition of ACER-001, with both patents expiring in 2036. Acer's New Drug Application (NDA) for ACER-001 is under review, with a target action date of June 5, 2022.

Relief Therapeutics Holding SA announced key resolutions approved at its Extraordinary General Meeting on January 28, 2022, with over 85% support. Notably, Michelle Lock was elected to the Board of Directors, bringing extensive experience from Acceleron Pharma. The meeting also approved a total compensation of CHF 2,500,000 for board members for the current term and revised the Articles of Association. Relief's lead drug candidate, RLF-100, is in late-stage testing for COVID-19 respiratory issues, while partnerships expand its pipeline for rare diseases.

Relief Therapeutics Holding SA announced that its partner, NRx Pharmaceuticals, received a safety report on aviptadil use in COVID-19 patients under the Federal Right to Try Law. Out of 19 treated patients, three died while 16 (84%) were alive by January 22, 2022. The report noted no serious adverse events during the Omicron surge. Relief focuses on developing therapies for serious conditions, with aviptadil in late-stage testing for respiratory failure due to COVID-19, alongside other pipeline projects including ACER-001.

Relief Therapeutics announced that its subsidiary, APR Applied Pharma Research, received a Notice of Allowance from the U.S. Patent and Trademark Office for a patent on diclofenac potassium formulations, extending protection until December 13, 2039. This patent covers ready-to-use oral solutions in stick packs for treating pain and migraine. The new formulation aims to enhance patient compliance. Current commercial rights for diclofenac are held by Assertio Therapeutics in the U.S. and Miravo Healthcare in Canada. The patent strengthens Relief's position in the market for non-steroidal anti-inflammatory drugs.

Relief Therapeutics Holding SA reported enhancements to the Expanded Access and Right to Try programs for aviptadil, enabling COVID-19 patients with respiratory failure to access treatment. These changes are made by their collaboration partner, NRx Pharmaceuticals. Patients who have exhausted all approved therapies can receive aviptadil via physician prescription, continuing under FDA guidelines. Relief's product, RLF-100 (aviptadil), is in late-stage trials for respiratory issues caused by COVID-19, while the company diversifies its pipeline through collaborations and acquisitions.

Relief Therapeutics commented on NRx Pharmaceuticals' press release regarding a lawsuit filed by NeuroRx against Relief. Relief asserts that the collaboration agreement for aviptadil remains valid and alleges that NeuroRx is in breach. The company refutes claims of financial impropriety and misleading statements made by NRx, asserting they are false and defamatory. Relief is poised to respond to NeuroRx's complaints and may file additional claims against them. The previously scheduled mediation date has been postponed due to NeuroRx's failure to provide required documentation.

Relief Therapeutics Holding SA announced that its collaboration partner, NeuroRx, has filed a lawsuit against it in New York, alleging breach of their collaboration agreement and defamation. Relief asserts that the agreement is still valid and disputes NeuroRx's claims. The company believes the lawsuit includes materially inaccurate statements and an illogical damages calculation. Relief plans to respond to the lawsuit and continues to participate in scheduled mediation with NeuroRx.

Relief Therapeutics announced that its partner, NRx Pharmaceuticals, submitted an application to the FDA for emergency use authorization (EUA) of aviptadil to treat COVID-19 patients at high risk of death. This application targets patients who are not eligible for the NIH-sponsored trial and are unresponsive to standard treatments like Remdesivir. Additionally, Relief is currently involved in a lawsuit against NeuroRx and its CEO, Jonathan Javitt, concerning their collaboration on aviptadil. The company remains optimistic about its legal claims and an upcoming mediation in February 2022.

Relief Therapeutics announced its participation in several virtual investor conferences in January 2022. The conferences include the H.C. Wainwright BioConnect Virtual Conference (January 10-13), where CFO Jack Weinstein will present an overview, and the Biotech Showcase 2022 (January 10-13, 17-19) for an additional corporate presentation. Relief's drug candidate, RLF-100, is in late-stage clinical testing for COVID-19 respiratory deficiency. The company is also expanding its pipeline through collaborations and acquisitions.