Relief Engages Jan-Jaap Scherpbier of Sonsbeek Pharma Consultancy B.V. as Manufacturing and Supply Chain Consultant

Rhea-AI Summary

Relief Therapeutics Holding AG has appointed J.J. Scherpbier as Manufacturing and Supply Chain Consultant, effective April 1, 2021. Mr. Scherpbier, with over 25 years of experience in pharmaceutical development, will focus on establishing a supply chain for ACER-001, a drug for Urea Cycle Disorders. The company aims to diversify its portfolio and enhance its development capabilities, particularly for RLF-100 (aviptadil), which is in late-stage testing for COVID-19 related respiratory issues. Relief is listed on the SIX Swiss Exchange (RLF) and OTCQB (RLFTF).

Positive

• Appointment of J.J. Scherpbier strengthens manufacturing and supply chain capabilities.
• Focus on establishing supply chain for ACER-001 may enhance drug commercialization efforts.
• Diverse portfolio strategy through collaboration with Acer Therapeutics supports growth.

Negative

• None.

GENEVA, SWITZERLAND / ACCESSWIRE / April 7, 2021 / RELIEF THERAPEUTICS Holding AG (SIX:RLF)(OTCQB:RLFTF) ("Relief" or the "Company"), a biopharmaceutical company with its lead compound RLF-100^TM (aviptadil) in advanced clinical development to treat COVID-19 induced respiratory disorders, today announced the appointment of J.J. Scherpbier of Sonsbeek Pharma Consultancy B.V. as Manufacturing and Supply Chain Consultant effective April 01, 2021. Mr. Scherpbier will support the Relief management team in all activities pertaining to manufacturing and supply projects across the Company's portfolio. Mr. Scherpbier will initially focus on the establishment of a supply chain in the Relief territory for ACER-001, a proprietary powder formulation of sodium phenylbutyrate (NaPB) designed to be both taste-masked and immediate release for the treatment of Urea Cycle Disorders.

Raghuram (Ram) Selvaraju, Chairman of the Board of Relief, said: "I am excited to welcome Jan-Jaap to the Relief team as we diversify our portfolio and take the next steps in the worldwide development and commercialization of ACER-001. His background and leadership in pharmaceutical development and GMP will provide critical support to the Relief management team."

Mr. Scherpbier is a highly experienced pharmaceutical consultant with more than 25 years of expertise in the areas of regulatory affairs, life cycle management, pharmaceutical development and GMP. Throughout his career, Mr. Scherpbier has worked in close cooperation with development, production and quality functions through participation in activities such as Technology Transfer, Trouble Shooting, Fact Finding and GMP enhancement. Mr. Scherpbier graduated as a pharmacist from the University of Groningen in the Netherlands and later obtained an M.Sc. Degree in Regulatory Affairs from the University of Wales.

"I look forward to hitting the ground running with Relief to support manufacturing and supply projects across their portfolio", said J.J. Scherpbier, Relief Manufacturing and Supply Chain Consultant. "In particular, I look forward to working closely with both the Relief and Acer teams to establish the world-wide supply chain and manufacturing capabilities for ACER-001. It is thrilling to have an opportunity to play a role in advancing the potential of a drug that supports patient therapeutic compliance and thus could improve their quality of life."

ABOUT RELIEF

Relief focuses primarily on clinical-stage programs based on molecules with a history of clinical testing and use in human patients or a strong scientific rationale. Relief's lead drug candidate RLF-100^TM (aviptadil), a synthetic form of Vasoactive Intestinal Peptide (VIP), is in late-stage clinical testing in the U.S. for the treatment of respiratory deficiency due to COVID-19. As part of its pipeline diversification strategy, in March 2021, Relief entered into a Collaboration and License Agreement with Acer Therapeutics for the worldwide development and commercialization of ACER-001. ACER-001 is a taste-masked and immediate release proprietary powder formulation of sodium phenylbutyrate (NaPB) for the treatment of Urea Cycle Disorders and Maple Syrup Urine Disease.

RELIEF THERAPEUTICS Holding AG is listed on the SIX Swiss Exchange under the symbol RLF and quoted in the U.S. on OTCQB under the symbol RLFTF. For more information, visit www.relieftherapeutics.com.

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CONTACT RELIEF THERAPEUTICS Holding AG Raghuram (Ram) Selvaraju, Ph.D., MBA Chairman of the Board Mail: contact@relieftherapeutics.com

FOR MEDIA/INVESTOR INQUIRIES: MC Services AG Anne Hennecke / Brittney Sojeva Tel.: +49 (0) 211-529-252-14 Mail: relief@mc-services.eu

Disclaimer: This communication expressly or implicitly contains certain forward-looking statements concerning RELIEF THERAPEUTICS Holding AG and its businesses. The results reported herein may or may not be indicative of the results of future and larger clinical trials for ACER-001 for the treatment of UCDs and MSUD, nor whether the ongoing clinical trials of Relief's lead compound, RLF-100(TM) (aviptadil) in advanced clinical development to treat respiratory deficiency due to COVID-19, will be successful. Such statements involve certain known and unknown risks, uncertainties and other factors, which could cause the actual results, financial condition, performance or achievements of RELIEF THERAPEUTICS Holding AG to be materially different from any future results, performance or achievements expressed or implied by such forward-looking statements. RELIEF THERAPEUTICS Holding AG is providing this communication as of this date and does not undertake to update any forward-looking statements contained herein as a result of new information, future events or otherwise.

SOURCE: Relief Therapeutics Holdings AG

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FAQ

What is the significance of J.J. Scherpbier's appointment at Relief Therapeutics?

J.J. Scherpbier's appointment enhances Relief Therapeutics' manufacturing and supply chain capabilities, crucial for the development of ACER-001.

What is ACER-001 and how does it relate to Relief Therapeutics?

ACER-001 is a proprietary formulation for treating Urea Cycle Disorders, and Relief is focusing on its development to diversify its portfolio.

What is the current status of Relief Therapeutics' lead compound RLF-100?

RLF-100 (aviptadil) is in advanced clinical testing for treating respiratory deficiencies related to COVID-19.

How does Relief Therapeutics plan to enhance its drug development efforts?

Relief Therapeutics aims to enhance its drug development efforts by focusing on effective manufacturing and establishing a supply chain for new drugs.

When was J.J. Scherpbier appointed as a consultant for Relief Therapeutics?

J.J. Scherpbier was appointed as Manufacturing and Supply Chain Consultant effective April 1, 2021.