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Roche Holdings Ltd. S/ADR (RHHBY) is a leading biotechnology company with a global presence in the field of in-vitro diagnostics. Roche focuses on scientific excellence to develop medicines and diagnostics for improving and saving lives. The company's pivotal role in personalized healthcare is reflected in its commitment to transforming healthcare delivery. Roche's innovative approach encompasses the discovery and development of cutting-edge treatments, including the first CD20xCD3 bispecific antibody, Columvi® (glofitamab), for relapsed or refractory diffuse large B-cell lymphoma (DLBCL). The company's recently FDA-cleared whole-slide imaging system, VENTANA DP 200, signifies Roche's dedication to revolutionizing pathology workflows through digitalization and artificial intelligence-based tools, ensuring pathologists can provide accurate and timely diagnoses. Roche's extensive portfolio and pipeline of haematology medicines demonstrate its unwavering commitment to advancing treatment options for patients worldwide.
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Roche (SIX: RO, ROG; OTCQX: RHHBY) announced the positive results of the Phase III HAVEN 7 study at the ASH 2023, reinforcing the efficacy and safety of Hemlibra in infants with severe haemophilia A without factor VIII inhibitors. The study showed meaningful bleed control in babies up to 12 months of age, with no spontaneous bleeds requiring treatment and no new safety signals observed. Hemlibra was well tolerated and exhibited consistent safety results. The study reflects Roche's commitment to advancing treatment standards for haemophilia A patients, providing additional confidence in the efficacy and safety profile of Hemlibra for babies with severe haemophilia A.
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Genentech, a member of the Roche Group (RO, ROG; RHHBY), announced the Phase III HAVEN 7 study results at ASH 2023, reinforcing the efficacy and safety of Hemlibra in infants with severe hemophilia A without factor VIII inhibitors. The study showed meaningful bleed control in babies up to 12 months of age and was well tolerated, with no new safety signals. Hemlibra provides a flexible and subcutaneous treatment option for babies, improving long-term outcomes and reducing the risk of intracranial hemorrhage.
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Roche (RO, ROG, RHHBY) presented positive results from the Phase III INAVO120 study, showing inavolisib in combination with palbociclib and fulvestrant more than doubled progression-free survival compared to palbociclib and fulvestrant alone for people with PIK3CA-mutated, HR-positive, HER2-negative, endocrine-resistant, locally advanced or metastatic breast cancer. The inavolisib combination reduced the risk of disease worsening or death by 57% and showed clinically meaningful increases in objective response rate, duration of response, and clinical benefit rate. Overall survival data were immature, but a clear positive trend was observed. The inavolisib combination was well tolerated, with no new safety signals observed. Inavolisib is currently being investigated in three Phase III clinical studies in people with PIK3CA-mutated locally advanced or metastatic breast cancer.
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Genentech (RO, ROG, RHHBY) releases positive long-term follow-up data from the pivotal, Phase III KATHERINE study in people with HER2-positive early-stage breast cancer. Kadcyla shows a statistically significant and clinically meaningful improvement in overall survival and maintains the previously reported invasive disease-free survival benefit. The safety profile of Kadcyla was consistent with previous findings and no new safety signals were identified.
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Roche (RO, ROG; RHHBY) announced positive results from the Phase III INAVO120 study of inavolisib in combination with palbociclib and fulvestrant for PIK3CA-mutated, HR-positive, HER2-negative, endocrine-resistant, locally advanced or metastatic breast cancer, showing a significant improvement in progression-free survival compared to palbociclib and fulvestrant alone.
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Roche (SIX: RO, ROG; OTCQX: RHHBY) is set to acquire Carmot Therapeutics in a definitive merger agreement, paying a purchase price of USD 2.7 billion upfront and additional milestone payments of up to USD 400 million. Carmot's R&D portfolio includes clinical stage incretins with best-in-class potential to treat obesity, diabetes, and other diseases. The lead asset CT-388 is a Phase-2 ready dual GLP-1/GIP agonist, with potential for treating obesity and its comorbidities. The acquisition gives Roche access to a differentiated portfolio of incretins, including CT-388, CT-996, and CT-868, offering opportunities for combination therapies and expansion to other indications.
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Roche (RO, ROG; RHHBY) has launched Elecsys® HBeAg quant, an immunoassay that determines the presence and quantity of the hepatitis B e antigen (HBeAg) in human serum and plasma. The test will aid in the diagnosis, disease phase determination, and treatment monitoring for patients with hepatitis B, a condition affecting almost 300 million people globally. The new diagnostic tool simplifies the testing process, improves operational efficiency, and enhances patient management.
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Genentech (RO, ROG; RHHBY) collaborates with NVIDIA to leverage AI for drug discovery and development. The multi-year strategic research collaboration aims to accelerate the delivery of novel therapies and medicines to people by transforming AI models and algorithms into a next-generation AI platform.
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Roche (SIX: RO, ROG; OTCQX: RHHBY) launches the LightCycler PRO System, an advanced qPCR technology designed for clinical diagnostics and research. The system aims to advance personalized healthcare and support outbreak readiness, offering agility and flexibility for translational research and diagnostics. It utilizes gold standard technology for quality, precision, and reliability, critical for accurate patient diagnosis and clinical decisions.
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Roche (SIX: RO, ROG; OTCQX: RHHBY) launches Elecsys Anti-HEV IgM and Elecsys Anti-HEV IgG immunoassays for hepatitis E virus (HEV) infections, contributing to global disease management. The tests aid in timely diagnosis, treatment, and surveillance, aligning with WHO's Essential Diagnostics List. They support patient care, disease burden estimation, and outbreak management, providing results in 18 minutes.
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FAQ
What is the current stock price of ROCHE HOLDING S/ADR (RHHBY)?
The current stock price of ROCHE HOLDING S/ADR (RHHBY) is $34.96 as of December 24, 2024.
What is the market cap of ROCHE HOLDING S/ADR (RHHBY)?
The market cap of ROCHE HOLDING S/ADR (RHHBY) is approximately 235.1B.
What is Roche Holdings Ltd. S/ADR (RHHBY) known for?
Roche is a global leader in biotechnology, specializing in in-vitro diagnostics and the development of cutting-edge medicines.
What is the significance of Columvi® (glofitamab) in Roche's portfolio?
Columvi® (glofitamab) is the first CD20xCD3 bispecific antibody that has shown promising results in treating relapsed or refractory diffuse large B-cell lymphoma (DLBCL).
How does Roche contribute to personalized healthcare?
Roche aims to transform healthcare delivery by focusing on scientific excellence, data insights, and partnerships with stakeholders to provide tailored treatment options for patients.
What recent innovation has Roche introduced in digital pathology?
Roche's VENTANA DP 200 whole-slide imaging system, with FDA clearance, allows pathologists to review and interpret digital pathology images efficiently, facilitating remote diagnosis and collaboration.
What is Roche's approach to advancing haematology treatments?
Roche has a robust portfolio and pipeline of haematology medicines, including T-cell engaging bispecific antibodies like Columvi®, to address the diverse needs of patients with blood cancers.
ROCHE HOLDING LTD S/ADR