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Renovaro Inc. and Amsterdam UMC Cancer Center Poised to Advance Cancer Immunotherapy

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Renovaro and Amsterdam UMC Cancer Center have signed an MoU to establish a joint company in the Netherlands, focused on personalized cancer immunotherapy. Combining Renovaro's cancer vaccine technology with the Cancer Center's expertise, the venture aims to overcome immunotherapy resistance. Subject to due diligence and executive board approvals, the new entity, 'Newco', will be headquartered in Amsterdam. The collaboration seeks to accelerate personalized cancer treatments and improve patient outcomes, leveraging shared resources and expertise.

Positive
  • Renovaro and Amsterdam UMC Cancer Center aim to combine proprietary cancer vaccine technology and ancillary immunomodulatory expertise, creating a potentially transformative advancement in cancer treatment.
  • A dedicated new entity, 'Newco', will be established in Amsterdam, enhancing focus and collaboration.
  • Both organizations will pool resources, expertise, and networks, ensuring a robust foundation for success.
  • The partnership signifies a strong commitment to innovation in cancer immunotherapy and improving patient outcomes.
  • Clinical activities will be relocated to Amsterdam, potentially benefiting from Europe's robust research infrastructure.
Negative
  • The partnership is still in the MoU stage, subject to corporate and scientific due diligence, and final approvals, making it uncertain.
  • There could be potential delays due to the requirement of independent validation and executive board approvals.
  • Risks associated with integrating different technological and operational frameworks from Renovaro and Amsterdam UMC.

Insights

The announcement of a partnership between Renovaro Inc. and the Amsterdam UMC Cancer Center has notable implications in the field of cancer immunotherapy. The collaboration aims to advance personalized cancer treatments, which could revolutionize the current approach to cancer therapy. Personalized immunotherapy involves tailoring treatments to individual patients based on their unique genetic profiles, potentially improving effectiveness and reducing side effects. The merging of Renovaro's vaccine technology with the Cancer Center's immunomodulatory expertise could create potent new therapies addressing immunotherapy resistance, a significant challenge in the field. If successful, this partnership could enhance patient outcomes and represent a step forward in the global fight against cancer. Investors should closely monitor the progress as it will affect both companies’ positions in the biotech sector.

From a financial perspective, this intended partnership carries both opportunities and risks. On the opportunity side, successful development of new personalized cancer treatments could significantly boost Renovaro's market position and revenue streams, considering the growing demand for innovative cancer therapies. However, there are inherent risks, including the need for extensive due diligence, regulatory approvals and potential delays in clinical trials. Additionally, the commitment of financial resources to this joint venture may impact short-term liquidity and profitability. Investors should weigh these factors, keeping in mind the high potential returns against the backdrop of substantial investment and operational risks.

LOS ANGELES and AMSTERDAM, May 24, 2024 (GLOBE NEWSWIRE) -- Renovaro Inc. (NASDAQ: RENB) and the Amsterdam UMC Cancer Center today announced an intended partnership and therefore signed an MoU to establish a joint company based in the Netherlands aimed at pioneering the next generation of personalized cancer immunotherapy. Both Renovaro and Amsterdam UMC emphasize the need to carry out the appropriate corporate and scientific due diligence before taking these next steps. Alongside the independent validation any final contractual commitments are subject to approval from both executive boards.

This collaboration would bring together Renovaro's proprietary cancer vaccine technology and the Cancer Center's expertise in several ancillary immunomodulatory technologies, towards innovative advancements in cancer treatment.

The proposed “Newco” will be headquartered in Amsterdam, The Netherlands. By merging Renovaro's cutting-edge vaccine technology with the Cancer Center's expertise, the aim is to develop personalized cancer immunotherapy solutions tailored to individual patients, overcoming immunotherapy resistance.

"We believe that by combining our expertise in cancer research and therapy with Renovaro's innovative allogenic dendritic vaccine technology, we can accelerate the development of personalized cancer treatments," said Prof. Geert Kazemier, Director of the Amsterdam UMC Cancer Center. "This once again represents our commitment to advancing cancer immunotherapy and improving patient outcomes."

"We are thrilled to partner with the Amsterdam UMC Cancer Center to drive innovation in cancer immunotherapy," said Coenraad K. van Kalken MD PhD, Director of RenovaroCube. "This collaboration represents a recognition of our potentially transformative technologies and a strategic alignment of our shared vision to change cancer treatment through personalized medicine. Also, as part of the MoU certain clinical activities would be moved to Amsterdam."

This new venture will operate independently, with a dedicated team of researchers collaborating closely with experts from both RenovaroBio and the Amsterdam UMC Cancer Center and will benefit from the combined resources, expertise, and extensive networks of its parent organizations, ensuring a strong foundation for success.

Both Renovaro and the Amsterdam UMC Cancer Center believe that the commitment to driving innovation in more non-invasive cancer therapies will enable significant strides in the fight against cancer, offering hope to patients worldwide.

About Renovaro Group:

Renovaro aims to accelerate precision and personalized medicine for longevity powered by mutually reinforcing AI and biotechnology platforms for early diagnosis, better-targeted treatments, and drug discovery. Renovaro Inc. includes RenovaroBio with its advanced cell-gene immunotherapy company and RenovaroCube. RenovaroCube has developed an award-winning AI platform that is committed to the early detection of cancer and its recurrence and monitoring subsequent treatments. RenovaroCube intervenes at a stage where potential therapy can be most effective. RenovaroCube is a molecular data science company with a background in FinTech and a 10-year history. It brings together proprietary artificial intelligence (AI) technology, multi-omics, multi-modal data, and the expertise of a carefully selected multidisciplinary team to radically accelerate precision medicine and enable breakthrough changes in cancer care.

Upon the closing of the previously announced acquisition of Cyclomics (winner of the Health Holland Venture Challenge), RenovaroCube will be capable of performing liquid biopsies using proprietary technologies to identify single cancer DNA molecules in only one vial of blood. In combination with Oxford Nanopore Technology, genetic information can be retrieved over multiple genetic layers to develop the next generation of cancer diagnostics. We believe this will transform cancer care by enabling faster and more accurate diagnosis throughout the patient journey.

About Amsterdam UMC/ CCA

With over 16,000 employees and 1,400 beds, Amsterdam UMC is one of the largest University Hospitals in the Benelux. The two locations of Amsterdam UMC, merged in 2020, work together to provide good and accessible care for millions of people. Amsterdam UMC focuses on a future where diseases can be prevented and where patients receive the best treatments. Amsterdam UMC has eight research institutes, the largest being the Cancer Center. The VUmc location (former Free University Hospital) emphasizes cancer and neurodegenerative disease research. The researchers affiliated are internationally recognized among the top in medical scientific research.

The Cancer Center Amsterdam was founded as a research institute over 25 years ago by Prof. Bob Pinedo and his colleagues to pursue innovative cancer research. Today, Cancer Center Amsterdam has become much more than an academic oncology center, encompassing all cancer care, research, and education at Amsterdam UMC. It is also aligned with the Cancer Center Amsterdam Foundation, which raises funds to empower promising developments in oncology research and patient care at Amsterdam UMC, and with Amsterdam UMC Holding, the corporate entity set up to actively bring highly promising medical innovation to the market.

Forward-Looking Statements

Statements in this press release that are not strictly historical in nature are forward-looking statements. These statements are only predictions based on current information and expectations and involve a number of risks and uncertainties, including but not limited to the success or efficacy of our pipeline and platform. All statements other than historical facts are forward-looking statements, which can be identified by the use of forward-looking terminology such as “believes,” “plans,” “expects,” “aims,” “intends,” “potential,” or similar expressions. Actual events or results may differ materially from those projected in any of such statements due to various uncertainties, including as set forth in Renovaro’s most recent Annual Report on Form 10-K filed with the SEC. Readers are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date hereof. All forward-looking statements are qualified in their entirety by this cautionary statement, and Renovaro Inc. undertakes no obligation to revise or update this press release to reflect events or circumstances after the date hereof.

For media inquiries, please contact: karen@renovarocube.com

Source: Renovaro Inc.


FAQ

What is the aim of Renovaro and Amsterdam UMC Cancer Center's partnership?

The partnership aims to develop personalized cancer immunotherapy by combining Renovaro's cancer vaccine technology with the Cancer Center's immunomodulatory expertise.

When was the partnership between Renovaro and Amsterdam UMC Cancer Center announced?

The partnership was announced on May 24, 2024.

What will the new joint company between Renovaro and Amsterdam UMC Cancer Center focus on?

The new joint company will focus on pioneering the next generation of personalized cancer immunotherapy.

Where will the new joint entity, 'Newco', be headquartered?

The new joint entity, 'Newco', will be headquartered in Amsterdam, The Netherlands.

What is the stock symbol for Renovaro?

The stock symbol for Renovaro is RENB.

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