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RAPT Therapeutics Reports Fourth Quarter and Year End 2021 Financial Results

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RAPT Therapeutics, Inc. reported its financial results for Q4 2021 and the full year, highlighting a net loss of $17.9 million for Q4 and $69.2 million for the year, an increase from $12.7 million and $52.9 million in 2020, respectively. R&D expenses rose to $14.3 million in Q4 and $57.0 million for the year due to clinical trial costs for RPT193 and FLX475. General and administrative expenses also increased to $4.5 million in Q4 and $16.0 million for the year. The company maintained a robust cash position of $189.7 million as of year-end.

Positive
  • Positive Phase 1b results for RPT193 in atopic dermatitis.
  • Plans to initiate Phase 2b trial for RPT193 in 2022.
  • Strong cash position of $189.7 million.
Negative
  • Increase in net loss to $69.2 million for the year.
  • R&D expenses rose by $11.5 million year-over-year.

Company maintains strong cash position of $189.7 million

SOUTH SAN FRANCISCO, Calif., March 10, 2022 (GLOBE NEWSWIRE) -- RAPT Therapeutics, Inc. (Nasdaq: RAPT), a clinical-stage, immunology-based biopharmaceutical company focused on discovering, developing and commercializing oral small molecule therapies for patients with significant unmet needs in inflammatory diseases and oncology, today reported financial results for the fourth quarter and year ended December 31, 2021.

“2021 was a significant year for RAPT, with progress in both of our lead programs,” said Brian Wong, M.D., Ph.D., President and Chief Executive Officer of RAPT Therapeutics. “We reported positive results for RPT193 from our Phase 1b clinical trial in atopic dermatitis and are excited about RPT193’s potential as a safe, once-daily oral drug for multiple inflammatory diseases. Based on those promising data, we plan to initiate a Phase 2b clinical trial of RPT193 in atopic dermatitis in the first half of 2022, as well as a Phase 2a trial in asthma in the second half of the year. For FLX475, we are continuing development in several indications including EBV+ lymphoma, nasopharyngeal cancer and head and neck cancer. We plan to provide an update on FLX475 in 2022 when we have data that are sufficiently mature from the ongoing cohorts.”

Financial Results for the Fourth Quarter and Year Ended December 31, 2021

Fourth Quarter Ended December 31, 2021

Net loss for the fourth quarter of 2021 was $17.9 million, compared to $12.7 million for the fourth quarter of 2020.

Research and development expenses for the fourth quarter of 2021 were $14.3 million, compared to $10.9 million for the same period in 2020. The increase in research and development expenses was primarily due to higher costs for the FLX475 and RPT193 clinical trials, personnel, facilities and laboratory supplies, partially offset by a decrease in stock-based compensation expense.

General and administrative expenses for the fourth quarter of 2021 were $4.5 million, compared to $3.5 million for the same period in 2020. The increase in general and administrative expenses was primarily due to increases in professional fees, personnel costs and insurance expenses, partially offset by a decrease in stock-based compensation expense.

Year Ended December 31, 2021

Net loss for the year ended December 31, 2021 was $69.2 million, compared to $52.9 million for the same period in 2020.

Research and development expenses for the year ended December 31, 2021 were $57.0 million, compared to $45.5 million for the same period in 2020. The increase in research and development expenses was primarily due to higher costs for the FLX475 and RPT193 clinical trials, personnel, facilities, stock-based compensation expense and laboratory supplies.

General and administrative expenses for the year ended December 31, 2021 were $16.0 million, compared to $12.8 million for the same period of 2020. The increase in general and administrative expenses was primarily due to increases in professional fees, insurance expense, personnel costs and stock-based compensation expense.

As of December 31, 2021, the Company had cash, cash equivalents and marketable securities of $189.7 million.

About RAPT Therapeutics, Inc.
RAPT Therapeutics is a clinical stage immunology-based biopharmaceutical company focused on discovering, developing and commercializing oral small molecule therapies for patients with significant unmet needs in inflammatory diseases and oncology. Utilizing its proprietary discovery and development engine, the Company is developing highly selective small molecules designed to modulate the critical immune drivers underlying these diseases. RAPT has discovered and advanced two unique drug candidates, RPT193 and FLX475, each targeting C-C motif chemokine receptor 4 (CCR4), for the treatment of inflammation and cancer, respectively. The Company is also pursuing a range of targets that are in the discovery stage of development.

Forward-Looking Statements
This press release contains forward-looking statements. These statements relate to future events and involve known and unknown risks, uncertainties and other factors that may cause our actual results, performance or achievements to be materially different from any future performances or achievements expressed or implied by the forward-looking statements. Each of these statements is based only on current information, assumptions and expectations that are inherently subject to change and involve a number of risks and uncertainties. Forward-looking statements include, but are not limited to, statements about clinical development progress and the timing of results from clinical trials of FLX475 and RPT193. Detailed information regarding risk factors that may cause actual results to differ materially from the results expressed or implied by statements in this press release may be found in RAPT’s Form 10-K filed with the Securities and Exchange Commission on March 10, 2022 and subsequent filings made by RAPT with the Securities and Exchange Commission. These forward-looking statements speak only as of the date hereof. RAPT disclaims any obligation to update these forward-looking statements.

RAPT Media Contact:
Aljanae Reynolds
areynolds@wheelhouselsa.com

RAPT Investor Contact:
Sylvia Wheeler
swheeler@wheelhouselsa.com 



RAPT THERAPEUTICS, INC.     
CONDENSED CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS     
(In thousands, except share per share data)     
(Unaudited)     
          
  Three Months Ended Year Ended 
  December 31, December 31, 
   2021   2020   2021   2020  
Revenue $756  $1,302  $3,813  $5,042  
Operating expenses:         
Research and development  14,299   10,904   56,985   45,485  
General and administrative  4,491   3,483   16,037   12,771  
Total operating expenses  18,790   14,387   73,022   58,256  
Loss from operations  (18,034)  (13,085)  (69,209)  (53,214) 
Other income, net  105   549   5   1,312  
Net loss before taxes  (17,929)  (12,536)  (69,204)  (51,902) 
Provision for income taxes     199      990  
Net loss $(17,929) $(12,735) $(69,204) $(52,892) 
Other comprehensive loss:         
Foreign currency translation adjustment  (23)  (184)  258   (249) 
Unrealized gain (loss) on marketable securities  (228)  (67)  (287)  52  
Total comprehensive loss $(18,180) $(12,986) $(69,233) $(53,089) 
Net loss per share, basic and diluted $(0.61) $(0.52) $(2.53) $(2.19) 
Weighted average number of shares used in computing net loss per share, basic and diluted  29,539,031   24,582,616   27,390,326   24,134,305  
          



RAPT THERAPEUTICS, INC.
CONDENSED CONSOLIDATED BALANCE SHEETS
(In thousands)
     
  December 31, December 31,
   2021   2020 
Assets (Unaudited)  (1) 
Current assets:    
Cash and cash equivalents $24,027  $24,918 
Marketable securities  165,627   86,592 
Prepaid expenses and other current assets  3,319   4,088 
Total current assets  192,973   115,598 
Property and equipment, net  2,741   2,982 
Other assets  2,922   389 
Total assets $198,636  $118,969 
Liabilities and stockholders' equity    
Current liabilities:    
Accounts payable $1,999  $2,383 
Accrued expenses  6,326   4,935 
Deferred revenue, current  1,016   4,096 
Other current liabilities  254   328 
Total current liabilities  9,595   11,742 
Deferred rent, net of current portion  2,150   2,185 
Deferred revenue, non-current  511   863 
Total liabilities  12,256   14,790 
Commitments    
Stockholders' equity:    
Preferred stock      
Common stock  3   2 
Additional paid-in capital  470,629   319,196 
Accumulated other comprehensive loss  (206)  (177)
Accumulated deficit  (284,046)  (214,842)
Total stockholders' equity  186,380   104,179 
Total liabilities and stockholders' equity $198,636  $118,969 
     
(1) The condensed consolidated balance sheet for December 31, 2020 has been derived from audited consolidated financial statements included in the Company’s Annual Report on Form 10-K for the year ended December 31, 2020


FAQ

What were RAPT Therapeutics' financial results for Q4 2021?

RAPT reported a net loss of $17.9 million for Q4 2021.

How much did RAPT Therapeutics lose in 2021?

The net loss for RAPT Therapeutics for the year 2021 was $69.2 million.

What is the current cash position of RAPT Therapeutics?

RAPT Therapeutics has a cash position of $189.7 million as of December 31, 2021.

What are RAPT's plans for RPT193 in 2022?

RAPT plans to initiate a Phase 2b clinical trial of RPT193 in atopic dermatitis in 2022.

What drove the increase in R&D expenses for RAPT in 2021?

R&D expenses increased due to higher costs for clinical trials of FLX475 and RPT193.

RAPT Therapeutics, Inc.

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Biotechnology
Pharmaceutical Preparations
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United States of America
SOUTH SAN FRANCISCO