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Quantum-Si’s Customers and Researchers to Showcase Next-Generation Protein Sequencing™ at AGBT 2025

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Quantum-Si (QSI) and several researchers will present new research and applications at the 2025 Advances in Genome Biology and Technology (AGBT) General Meeting from February 23-26th. The presentations will include three scientific posters showcasing Next-Generation Protein Sequencing (NGPS™) innovations:

1. Dr. Meredith Carpenter from Quantum-Si will present how NGPS detects protein-level changes and post-translational modifications

2. Dr. Gloria Sheynkman from University of Virginia will demonstrate the integration of long-read RNA sequencing with the Platinum™ benchtop instrument for single-molecule peptide sequencing

3. Dr. Winston Timp from Johns Hopkins University will showcase how NGPS enables direct peptide sequencing to identify protein partners, offering a cost-effective alternative to legacy technologies

Quantum-Si (QSI) e diversi ricercatori presenteranno nuove ricerche e applicazioni al 2025 Advances in Genome Biology and Technology (AGBT) General Meeting che si svolgerà dal 23 al 26 febbraio. Le presentazioni includeranno tre poster scientifici che metteranno in evidenza le innovazioni nel Sequenziamento Proteico di Nuova Generazione (NGPS™):

1. La Dr.ssa Meredith Carpenter di Quantum-Si presenterà come il NGPS rileva cambiamenti a livello di proteine e modifiche post-traduzionali.

2. La Dr.ssa Gloria Sheynkman dell'Università della Virginia dimostrerà l'integrazione del sequenziamento RNA a lettura lunga con lo strumento da banco Platinum™ per il sequenziamento di peptidi a singola molecola.

3. Il Dr. Winston Timp della Johns Hopkins University mostrerà come il NGPS consente il sequenziamento diretto dei peptidi per identificare i partner proteici, offrendo un'alternativa economica alle tecnologie tradizionali.

Quantum-Si (QSI) y varios investigadores presentarán nuevas investigaciones y aplicaciones en la Reunión General de Avances en Biología Genómica y Tecnología (AGBT) 2025 del 23 al 26 de febrero. Las presentaciones incluirán tres carteles científicos que mostrarán innovaciones en el Secuenciación de Proteínas de Nueva Generación (NGPS™):

1. La Dra. Meredith Carpenter de Quantum-Si presentará cómo NGPS detecta cambios a nivel de proteínas y modificaciones post-traduccionales.

2. La Dra. Gloria Sheynkman de la Universidad de Virginia demostrará la integración de la secuenciación de RNA de lectura larga con el instrumento de banco Platinum™ para el secuenciamiento de péptidos de molécula única.

3. El Dr. Winston Timp de la Universidad Johns Hopkins mostrará cómo NGPS permite el secuenciamiento directo de péptidos para identificar socios proteicos, ofreciendo una alternativa rentable a las tecnologías tradicionales.

Quantum-Si (QSI)와 여러 연구자들이 2025 유전체 생물학 및 기술의 발전(AGBT) 총회에서 2월 23일부터 26일까지 새로운 연구와 응용을 발표할 예정입니다. 발표에는 차세대 단백질 서열 분석(NGPS™) 혁신을 보여주는 세 가지 과학 포스터가 포함됩니다:

1. Quantum-Si의 Meredith Carpenter 박사는 NGPS가 단백질 수준의 변화와 번역 후 변형을 어떻게 감지하는지 발표할 것입니다.

2. 버지니아 대학교의 Gloria Sheynkman 박사는 단일 분자 펩타이드 서열 분석을 위한 Platinum™ 벤치탑 장비와의 장기 읽기 RNA 서열 분석 통합을 시연할 것입니다.

3. Johns Hopkins 대학교의 Winston Timp 박사는 NGPS가 단백질 파트너를 식별하기 위해 직접 펩타이드 서열 분석을 가능하게 하여 기존 기술에 대한 비용 효율적인 대안을 제공하는 방법을 보여줄 것입니다.

Quantum-Si (QSI) et plusieurs chercheurs présenteront de nouvelles recherches et applications lors de la Réunion Générale 2025 sur les Avancées en Biologie Génomique et Technologie (AGBT) qui se tiendra du 23 au 26 février. Les présentations comprendront trois affiches scientifiques mettant en avant les innovations dans le Séquençage de Protéines de Nouvelle Génération (NGPS™) :

1. Dr. Meredith Carpenter de Quantum-Si présentera comment le NGPS détecte les changements au niveau des protéines et les modifications post-traductionnelles.

2. Dr. Gloria Sheynkman de l'Université de Virginie démontrera l'intégration du séquençage RNA à lecture longue avec l'instrument de paillasse Platinum™ pour le séquençage de peptides à molécule unique.

3. Dr. Winston Timp de l'Université Johns Hopkins montrera comment le NGPS permet le séquençage direct des peptides pour identifier les partenaires protéiques, offrant une alternative rentable aux technologies traditionnelles.

Quantum-Si (QSI) und mehrere Forscher werden neue Forschungsarbeiten und Anwendungen auf dem 2025 Advances in Genome Biology and Technology (AGBT) General Meeting vom 23. bis 26. Februar präsentieren. Die Präsentationen umfassen drei wissenschaftliche Poster, die Innovationen in der Next-Generation Protein Sequencing (NGPS™) zeigen:

1. Dr. Meredith Carpenter von Quantum-Si wird präsentieren, wie NGPS Veränderungen auf Proteinebene und posttranslationale Modifikationen erkennt.

2. Dr. Gloria Sheynkman von der Universität von Virginia wird die Integration der Langzeit-RNA-Sequenzierung mit dem Platinum™-Benchtop-Gerät zur Einzelmolekül-Peptidsequenzierung demonstrieren.

3. Dr. Winston Timp von der Johns Hopkins University wird zeigen, wie NGPS das direkte Peptidsequencing ermöglicht, um Proteinpartner zu identifizieren und eine kostengünstige Alternative zu herkömmlichen Technologien bietet.

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  • Multiple prestigious academic institutions are adopting and validating QSI's technology
  • Company's Platinum™ instrument demonstrates practical applications in research settings
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BRANFORD, Conn.--(BUSINESS WIRE)-- Quantum-Si Incorporated (Nasdaq: QSI) (“Quantum-Si,” “QSI” or the “Company”), The Protein Sequencing Company, and several distinguished researchers will be presenting new research and applications at the 2025 Advances in Genome Biology and Technology (AGBT) General Meeting February 23-26th.

Quantum-Si, the pioneer in Next-Generation Protein Sequencing (NGPS™) will feature groundbreaking research through one company-led poster and two customer-led posters highlighting the transformative capabilities of NGPS in multi-omics research and drug discovery.

Scientific Posters Highlighting NGPS Innovation

Beyond the genome: Advancing our understanding of the proteome with Next-Generation Protein Sequencing

  • Presenter: Meredith Carpenter, Ph.D., Head of Scientific Affairs, Quantum-Si
  • Introduces how NGPS offers an integrated understanding of cellular processes by detecting changes at the protein level (such as post-translational modifications, or PTMs) that cannot be captured by genomics data alone.
  • February 25th, Poster 412

Integrating long-read RNAseq and Next-Generation Protein Sequencing™ to explore proteoform variability

  • Presenter: Gloria Sheynkman, Ph.D., Assistant Professor, University of Virginia
  • Demonstrates the integration of long-read RNA sequencing to capture transcript isoforms, combined with the benchtop instrument Platinum™ to produce single-molecule peptide sequencing data.
  • February 25th Poster 476

Identifying Protein Binding Partners at the Bench Using Quantum-Si

  • Presenter: Winston Timp, Ph.D., Associate Professor, BioMedical Engineering and Molecular Biology and Genetics, Johns Hopkins University
  • Demonstrates how NGPS enables direct peptide sequencing to identify protein partners regulated by genomic, epigenomic, or splicing variation, offering a rapid and cost-effective alternative to legacy technologies.
  • February 24th, Poster 465

About Quantum-Si Incorporated

Quantum-Si, The Protein Sequencing Company™, is focused on revolutionizing the growing field of proteomics. The Company’s Platinum® line of instruments enables Next-Gen Protein Sequencing™ that advances proteomic research, drug discovery, and diagnostics beyond what has been possible with existing proteomic tools. Learn more at quantum-si.com or follow us on LinkedIn or X.

Investor Contact

Jeff Keyes

Chief Financial Officer

ir@quantum-si.com



Media Contact

Katherine Atkinson

SVP, Commercial Marketing

media@quantum-si.com

Source: Quantum-Si Incorporated

FAQ

What research will be presented at AGBT 2025 featuring Quantum-Si's technology?

Three scientific posters will be presented: one by QSI on protein-level changes detection, one by University of Virginia on RNA sequencing integration, and one by Johns Hopkins University on protein partner identification using NGPS technology.

How is Quantum-Si's Platinum™ instrument being used in academic research?

The Platinum™ instrument is being used for single-molecule peptide sequencing and is being integrated with long-read RNA sequencing to explore proteoform variability.

What advantages does QSI's Next-Generation Protein Sequencing offer over existing technologies?

NGPS offers detection of post-translational modifications, provides integrated understanding of cellular processes, and presents a rapid, cost-effective alternative to legacy technologies for identifying protein binding partners.

Which academic institutions are presenting research using Quantum-Si's technology at AGBT 2025?

The University of Virginia and Johns Hopkins University will be presenting research using Quantum-Si's technology at AGBT 2025.

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