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Company Overview
Quantum-Si Incorporated (QSI) is a specialized life sciences company dedicated to revolutionizing proteomics research with its cutting-edge approach to single-molecule detection and next-generation protein sequencing (NGPS). By leveraging a proprietary universal detection platform, the company delivers comprehensive solutions that integrate sophisticated hardware, purpose-designed consumables, and intuitive software tools. This holistic approach enables researchers to conduct protein analysis with unprecedented precision, addressing critical challenges in biomolecular discovery and diagnostics.
Innovative Platform and Technology
At the heart of Quantum-Si's business model is its innovative universal single-molecule detection platform. Designed to streamline the process of protein sequencing, the system is engineered to break down complex biological samples into quantifiable data, thereby accelerating the pace of discovery in proteomics. The integration of hardware, consumables, and software into a cohesive solution not only enhances data quality but also reduces operational complexities for high-commitment research teams. This technological synergy distinguishes Quantum-Si within the competitive landscape of biotechnology research instruments.
Operational Excellence and Environment
Quantum-Si has cultivated a unique work environment that encourages bright, committed individuals to innovate and solve challenging scientific problems. By empowering its team with the freedom to explore new scientific approaches and providing adequate resources, the company fosters a culture where creativity and rigorous scientific inquiry go hand in hand. This commitment to operational excellence is fundamental to developing products that effectively address the needs of researchers and professionals in the life sciences community.
Market Position and Competitive Landscape
Operating in the dynamic realm of proteomics, Quantum-Si holds an important niche in the biotech industry by addressing specific challenges related to protein detection and analysis. The company has strategically positioned itself against competitors by focusing on the deployment of its advanced, single-molecule detection technology, emphasizing its capacity for next-generation protein sequencing. Researchers and healthcare professionals seeking precise and efficient proteomic analysis find Quantum-Si's product offerings uniquely suited to drive scientific innovation and improved research outcomes.
Business Model and Revenue Generation
The company generates revenue through the commercialization of its proprietary detection platform, offering a blend of hardware, consumable products, and integrated software solutions. This approach not only creates multiple revenue streams but also anchors the company's position as a significant contributor to the proteomics research sector. Quantum-Si's business model is built upon delivering high-performance, reliable instruments to research institutions and laboratories globally, ensuring that the practical applications of its technology are both scalable and transformative.
Commitment to Quality and Expertise
Quantum-Si demonstrates a strong commitment to quality through a methodical approach to product development and validation. By embedding industry best practices into its research and development processes, the company ensures that every aspect of its technology—from hardware precision to software analytics—upholds a high standard of scientific reliability. This relentless pursuit of excellence underscores the firm’s dedication to advancing scientific discovery while maintaining robust operational frameworks.
Addressing Industry Needs with Advanced Proteomics Solutions
In a rapidly evolving scientific landscape, Quantum-Si continues to be driven by a mission to empower breakthroughs in health and discovery. Its universal detection platform addresses long-standing challenges in protein identification and sequencing, offering a unique solution that amalgamates technological innovation with practical application. The company is vocally committed to nurturing a culture of innovation and scientific rigor among its employees, ensuring that its technological advancements remain at the forefront of proteomics research.
In summary, Quantum-Si Incorporated stands out as a distinguished enterprise in the life sciences field due to its advanced proteomics research tools and its integrated approach to technology. The comprehensive suite of solutions provided by the company not only underlines its expertise in single-molecule detection and next-generation protein sequencing but also reinforces its relevance within the broader biotechnology ecosystem.
Quantum-Si (Nasdaq: QSI) has begun shipping its latest benchtop protein sequencer, Platinum® Pro, designed to make Next-Gen Protein Sequencing™ more accessible globally. The new system builds upon the original Platinum model with enhanced features including:
- An enlarged touchscreen with intuitive user interface
- Flexible local or cloud-based data analysis options
- Pro Mode for custom application development through a Technology Access Program
The system offers single-molecule precision protein analysis through an integrated workflow and is now available in over 30 countries through direct and channel partner networks. According to CEO Jeff Hawkins, Platinum Pro aims to advance proteomics research and enable new biomarker discoveries.
Quantum-Si (Nasdaq: QSI), The Protein Sequencing Company™, has announced its participation in an upcoming DNAnexus webinar focused on proteomics in multi-omics research. The virtual event, scheduled for March 25, 2025, at 8 a.m. PT/11 a.m. ET, will explore how integrating proteomics data with other omics datasets drives new discoveries in disease research, including cancer.
Featured speakers include Meredith Carpenter, PhD from Quantum-Si, Cindy Lawley, PhD from Olink, Thermo Fisher Scientific, and Theresa Wohlever from DNAnexus. The webinar will cover:
- The growing impact of proteomics in multi-omics analysis
- Applications for cancer and other disease research
- Technologies and strategies for large-scale discovery and data analysis
- Tools for orthogonal validation of proteins of interest
Quantum-Si (Nasdaq: QSI), The Protein Sequencing Company™, has announced its participation in an upcoming DNAnexus webinar focused on proteomics in multi-omics research. The virtual event, scheduled for March 25, 2025, at 8 a.m. PT/11 a.m. ET, will explore how integrating proteomics data with other omics datasets drives new discoveries in disease research, including cancer.
Key speakers include Meredith Carpenter, PhD from Quantum-Si, Cindy Lawley, PhD from Olink, Thermo Fisher Scientific, and Theresa Wohlever from DNAnexus. The webinar will cover:
- The growing impact of proteomics in multi-omics analysis
- Applications for cancer and other disease research
- Technologies and strategies for large-scale discovery and data analysis
- Tools for orthogonal validation of proteins of interest
Quantum-Si (Nasdaq: QSI) has announced new employee inducement grants approved by its Board's Compensation Committee. The company granted 20,833 restricted stock units (RSUs) to new employees under its 2023 Inducement Equity Incentive Plan, in accordance with Nasdaq Listing Rule 5635(c)(4).
The RSUs vesting schedule includes 25% vesting on March 20, 2026, with the remaining portion vesting in 12 equal quarterly installments thereafter. Vesting is contingent upon continued employment with Quantum-Si. These equity awards are specifically designed for new hires who were not previously employed by the company, serving as an inducement for joining Quantum-Si.
Quantum-Si (QSI) reported strong Q4 and full year 2024 financial results, achieving its first quarterly revenue over $1 million. Q4 revenue reached $1.2 million with a 51% gross margin, while full-year 2024 revenue totaled $3.1 million, representing 183% year-over-year growth.
The company successfully raised over $86 million in capital between Q4 2024 and early 2025, extending its cash runway into H2 2027. Key developments include the launch of Platinum® Pro in January 2025, new v2 Library Preparation Kit, and Barcoding Kit in December 2024. QSI reported a Q4 net loss of $33.1 million and full-year net loss of $101.0 million.
With $209.6 million in cash and investments as of December 31, 2024, QSI expects significant revenue growth in 2025, supported by new commercial partnerships with Avantor and international distributors.
Quantum-Si (QSI) and several researchers will present new research and applications at the 2025 Advances in Genome Biology and Technology (AGBT) General Meeting from February 23-26th. The presentations will include three scientific posters showcasing Next-Generation Protein Sequencing (NGPS™) innovations:
1. Dr. Meredith Carpenter from Quantum-Si will present how NGPS detects protein-level changes and post-translational modifications
2. Dr. Gloria Sheynkman from University of Virginia will demonstrate the integration of long-read RNA sequencing with the Platinum™ benchtop instrument for single-molecule peptide sequencing
3. Dr. Winston Timp from Johns Hopkins University will showcase how NGPS enables direct peptide sequencing to identify protein partners, offering a cost-effective alternative to legacy technologies
Quantum-Si (Nasdaq: QSI) announces its participation at the US Human Proteome Organization's 2025 conference in Philadelphia, featuring advances in Next-Generation Protein Sequencing™ (NGPS™). The company is sponsoring a panel discussion titled 'Breaking Boundaries: How Next-Generation Protein Sequencing™ is Shaping the Future of Proteomics' on February 25.
The event will showcase research using Quantum-Si's Platinum® Pro benchtop instrument, including new protein barcoding and library preparation solutions. Notable researchers from Washington University, University of Illinois Chicago, and University of Michigan will discuss NGPS's impact on proteomics.
Four scientific posters will be presented, covering: tropomyosin isoform differentiation, reduced protein input requirements, peptide variant mixture measurement, and protein barcoding for multiplexed analysis.
Quantum-Si (QSI) has announced it will release its fourth quarter and full year 2024 financial results on Monday, March 3, 2025. The company will host a conference call and webcast at 4:30 PM ET on the same day, featuring President and CEO Jeff Hawkins and CFO Jeff Keyes, who will discuss the financial results and provide a business update.
Interested participants can join via webcast through the Investors section of Quantum-Si's website under Events and Presentations, or register for a personalized dial-in number. A replay of the event will be available afterward.
Quantum-Si (Nasdaq: QSI) announces a new preprint from Northwestern University researchers demonstrating the combined use of their Next-Generation Protein Sequencing™ (NGPS™) technology and Individual Ion Mass Spectrometry (I2MS) for analyzing interleukin-6 (IL-6), a key immune regulator and therapeutic target.
The study reveals that NGPS provided single amino acid resolution for IL-6 peptide fragments critical to receptor binding and function, while I2MS enabled intact proteoform detection and localized modifications, including glycosylation. The combination of these technologies offers comprehensive coverage of IL-6's structural and functional diversity, potentially advancing therapeutic research in complex diseases like cancer and autoimmune disorders.
Quantum-Si (Nasdaq: QSI) has announced the formation of its Scientific Advisory Board (SAB) to guide its next-generation proteomic technologies development. Dr. Gloria M. Sheynkman, Assistant Professor at the University of Virginia, has been appointed as Chair of the SAB. The board includes distinguished experts in proteomics, genomics, bioinformatics, chemistry, and engineering.
Key board members include Dr. Benjamin A. Garcia from Washington University School of Medicine, Dr. Bradley L. Pentelute from MIT, and Dr. Denis Zaccarin, former Senior VP of R&D at PacBio. The SAB will focus on shaping scientific strategy, identifying emerging trends, and strengthening scientific community engagement. They will also support Quantum-Si in prioritizing applications and fostering collaborations for their next-generation protein sequencing (NGPS) technology and Proteus™ platform.
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