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Palvella Therapeutics has completed its merger with Pieris Pharmaceuticals and will trade on Nasdaq as PVLA. The company raised $78.9 million in a private placement co-led by BVF Partners and Frazier Life Sciences. With approximately $80.0 million in cash, operations are funded into second half of 2027.
The company's lead product, QTORIN™ rapamycin, is being developed for microcystic lymphatic malformations (LMs) and cutaneous venous malformations. The drug has received FDA Breakthrough Therapy, Fast Track, and Orphan Drug Designations. A Phase 3 SELVA trial for microcystic LMs is currently enrolling approximately 40 subjects.
Post-merger, former Pieris stockholders own 11% and Palvella stockholders hold 89% of the combined company. The merger was approved by both companies' stockholders in December 2024.
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