Plus Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Recent Business Highlights
Plus Therapeutics (PSTV) has reported its Q4 and full year 2024 financial results, highlighting significant developments in its CNS cancer therapeutics programs. The company secured a $15 million private placement financing, regaining Nasdaq compliance and extending runway into 2026, along with a $2 million grant advance from CPRIT.
Key highlights include FDA brand name approval for REYOBIQ, promising Phase 1 clinical trial results showing doubled median survival rates for glioblastoma patients, and FDA Orphan Drug Designation for leptomeningeal metastases treatment. The company strengthened its management team and expanded its agreement with Telix IsoTherapeutics for Rhenium-186 supply.
Financial results show $3.6 million in cash and investments as of December 31, 2024, $5.8 million in grant revenue, and a net loss of $13.0 million ($1.95 per basic share) for 2024.
Plus Therapeutics (PSTV) ha riportato i risultati finanziari del quarto trimestre e dell'intero anno 2024, evidenziando sviluppi significativi nei suoi programmi terapeutici per il cancro del sistema nervoso centrale. L'azienda ha ottenuto un finanziamento privato di 15 milioni di dollari, recuperando la conformità al Nasdaq e prolungando la propria disponibilità fino al 2026, insieme a un anticipo di sovvenzione di 2 milioni di dollari da CPRIT.
I punti salienti includono l'approvazione del nome commerciale da parte della FDA per REYOBIQ, risultati promettenti della fase 1 degli studi clinici che mostrano raddoppiati tassi di sopravvivenza mediana per i pazienti affetti da glioblastoma, e la designazione di Farmaco Orfano da parte della FDA per il trattamento delle metastasi leptomeningeal. L'azienda ha rafforzato il proprio team di gestione e ampliato l'accordo con Telix IsoTherapeutics per la fornitura di Rhenium-186.
I risultati finanziari mostrano 3,6 milioni di dollari in contante e investimenti al 31 dicembre 2024, 5,8 milioni di dollari in ricavi da sovvenzioni e una perdita netta di 13,0 milioni di dollari (1,95 dollari per azione ordinaria) per il 2024.
Plus Therapeutics (PSTV) ha reportado sus resultados financieros del cuarto trimestre y del año completo 2024, destacando desarrollos significativos en sus programas terapéuticos para el cáncer del sistema nervioso central. La compañía aseguró un financiamiento privado de 15 millones de dólares, recuperando la conformidad con Nasdaq y extendiendo su capital hasta 2026, junto con un adelanto de subvención de 2 millones de dólares de CPRIT.
Los puntos destacados incluyen la aprobación del nombre comercial por parte de la FDA para REYOBIQ, resultados prometedores de ensayos clínicos de fase 1 que muestran tasas de supervivencia mediana duplicadas para pacientes con glioblastoma, y la designación de Medicamento Huérfano por parte de la FDA para el tratamiento de metástasis leptomeníngeas. La compañía fortaleció su equipo de gestión y amplió su acuerdo con Telix IsoTherapeutics para el suministro de Rhenium-186.
Los resultados financieros muestran 3,6 millones de dólares en efectivo e inversiones al 31 de diciembre de 2024, 5,8 millones de dólares en ingresos por subvenciones y una pérdida neta de 13,0 millones de dólares (1,95 dólares por acción básica) para 2024.
Plus Therapeutics (PSTV)는 2024년 4분기 및 연간 재무 결과를 보고하며, CNS 암 치료 프로그램에서의 중요한 발전을 강조했습니다. 회사는 1500만 달러의 사모펀드 자금 조달을 확보하여 Nasdaq 규정을 준수하고 2026년까지 자금을 연장했으며, CPRIT로부터 200만 달러의 보조금 선지급을 받았습니다.
주요 하이라이트로는 REYOBIQ에 대한 FDA 상표 승인, 교모세포종 환자를 위한 중앙 생존율이 두 배로 증가한 1상 임상 시험 결과, 그리고 지주막 전이 치료를 위한 FDA 고아약 지정이 포함됩니다. 회사는 경영진을 강화하고 Rhenium-186 공급을 위한 Telix IsoTherapeutics와의 계약을 확대했습니다.
재무 결과는 2024년 12월 31일 기준으로 360만 달러의 현금 및 투자, 580만 달러의 보조금 수익, 그리고 1300만 달러의 순손실(기본 주당 1.95달러)을 보여줍니다.
Plus Therapeutics (PSTV) a publié ses résultats financiers du quatrième trimestre et de l'année complète 2024, mettant en avant des développements significatifs dans ses programmes thérapeutiques contre le cancer du système nerveux central. L'entreprise a sécurisé un financement par placement privé de 15 millions de dollars, retrouvant la conformité avec le Nasdaq et prolongeant son capital jusqu'en 2026, ainsi qu'un avance de subvention de 2 millions de dollars de CPRIT.
Les points clés incluent l'approbation par la FDA du nom commercial REYOBIQ, des résultats prometteurs d'essais cliniques de phase 1 montrant des taux de survie médians doublés pour les patients atteints de glioblastome, et la désignation de Médicament Orphelin par la FDA pour le traitement des métastases leptomeningeales. L'entreprise a renforcé son équipe de direction et élargi son accord avec Telix IsoTherapeutics pour la fourniture de Rhenium-186.
Les résultats financiers montrent 3,6 millions de dollars en liquidités et investissements au 31 décembre 2024, 5,8 millions de dollars de revenus de subventions, et une perte nette de 13,0 millions de dollars (1,95 dollar par action ordinaire) pour 2024.
Plus Therapeutics (PSTV) hat seine Finanzzahlen für das vierte Quartal und das gesamte Jahr 2024 veröffentlicht und dabei bedeutende Entwicklungen in seinen therapeutischen Programmen für Krebs des zentralen Nervensystems hervorgehoben. Das Unternehmen sicherte sich eine Privatplatzierung in Höhe von 15 Millionen Dollar, stellte die Nasdaq-Konformität wieder her und verlängerte die Finanzierungsdauer bis 2026, zusammen mit einem Vorschuss von 2 Millionen Dollar von CPRIT.
Zu den wichtigsten Highlights gehören die FDA-Zulassung des Markennamens REYOBIQ, vielversprechende Ergebnisse der Phase-1-Studien, die eine verdoppelte mediane Überlebensrate für Glioblastom-Patienten zeigen, sowie die FDA-Einstufung als Orphan Drug für die Behandlung von leptomeningealen Metastasen. Das Unternehmen hat sein Managementteam gestärkt und seine Vereinbarung mit Telix IsoTherapeutics zur Lieferung von Rhenium-186 erweitert.
Die finanziellen Ergebnisse zeigen 3,6 Millionen Dollar an Bargeld und Investitionen zum 31. Dezember 2024, 5,8 Millionen Dollar an Zuschusseinnahmen und einen Nettoverlust von 13,0 Millionen Dollar (1,95 Dollar pro Stammaktie) für 2024.
- $15M private placement financing secured, extending runway into 2026
- Phase 1 trial showed doubled survival rates for glioblastoma patients
- FDA Orphan Drug Designation received for REYOBIQ in LM treatment
- Grant revenue increased to $5.8M from $4.9M year-over-year
- Strategic agreement expanded with Telix for Rhenium-186 supply
- Operating loss increased to $14.7M from $13.3M year-over-year
- Cash position decreased to $3.6M from $8.6M year-over-year
- Net loss of $13.0M in 2024
Insights
Plus Therapeutics' financial position shows significant improvement with the recent
Their year-end cash position of
The anticipated 2025 commercial launch of CNSide represents a pivotal transition to a revenue-generating business model. This diagnostic platform could provide recurring revenue streams to partially offset R&D expenses while they advance REYOBIQ toward potential approval. The
These developments signal Plus is successfully executing its capital strategy during the historically challenging pre-commercialization phase for biotech companies. Their strategic partnership with Telix IsoTherapeutics also secures their supply chain for late-stage trials and potential commercialization, mitigating a significant operational risk.
Plus Therapeutics' clinical data progression presents compelling evidence of REYOBIQ's potential as a targeted radiotherapeutic for CNS cancers. The Nature Communications publication documenting Phase 1 results for recurrent glioblastoma reveals a remarkable doubling of median overall survival to 17 months for patients receiving radiation doses >100 Gy, compared to standard of care.
The completion of the ReSPECT-LM Phase 1 single-dose trial represents a crucial development milestone, establishing both maximum feasible dose and recommended Phase 2 dosing parameters. This achievement, coupled with the FDA's Orphan Drug Designation for REYOBIQ in leptomeningeal metastases from lung cancer, strengthens their regulatory position and potential market exclusivity.
The company's diagnostic platform, CNSide, shows particular promise for transforming LM management based on multi-institutional data presented at neuro-oncology conferences. The platform's ability to enhance diagnosis and longitudinal monitoring addresses a significant unmet need in CNS cancer management.
Their pipeline diversification strategy appears sound, with trials spanning multiple CNS cancers including the planned pediatric brain cancer application. The parallel advancement of diagnostic and therapeutic technologies creates potential synergies that few competitors can match. The strategic partnership securing cGMP Rhenium-186 supply resolves a critical manufacturing challenge that often hampers radiopharmaceutical development programs.
The recent
HOUSTON, March 27, 2025 (GLOBE NEWSWIRE) -- Plus Therapeutics, Inc. (Nasdaq: PSTV) (the “Company”), a clinical-stage pharmaceutical company developing targeted radiotherapeutics with advanced platform technologies for central nervous system (CNS) cancers, today announces financial results for the fourth quarter and full year ended December 31, 2024, and provides an overview of recent and upcoming business highlights.
“Over the last twelve months, Plus has reported very promising safety and efficacy data for our lead drug REYOBIQ administered in our two most advanced CNS cancer programs,” said Marc H. Hedrick, M.D., Plus Therapeutics President and Chief Executive Officer. “The recently raised capital, coupled with existing grant support, enables us to progress both our therapeutic programs to key clinical and regulatory milestones as well as commercially launch our CNSide diagnostic platform. The year 2025 has the potential to be transformational at Plus as we anticipate transitioning to an operational revenue generating company with the launch of CNSide. We are highly appreciative of our investors, partners and other stakeholders for their continued commitment to Plus as we deliver on our objectives and drive value.”
Q4 2024 & RECENT HIGHLIGHTS AND MILESTONES
Corporate
- Raised
$15.0 million in a private placement financing, enabling the Company to regain compliance with Nasdaq minimum stockholders’ equity requirement and extending runway into 2026 - Obtained a
$2.0 million grant award advance from the Company’s existing$17.6 million grant from the Cancer Prevention and Research Institute of Texas (CPRIT) to accelerate the development of REYOBIQ for our leptomeningeal metastases (LM) program - Strengthened management team with key leadership appointments:
- Dr. Michael Rosol as Chief Development Officer - Dr. Rosol will lead the Company’s clinical, pre-clinical, and biomarker development activities
- Mr. Russell Bradley as President and General Manager of Plus Therapeutics’ wholly owned subsidiary, CNSide Diagnostics, LLC (“CNSide Diagnostics”) - Mr. Bradley will provide leadership at CNSide with an immediate focus on commercialization of the diagnostic platform
- Dr. Jonathan Stein as Medical Director, CNSide Diagnostics - Dr. Stein will provide technical leadership to support CNSide Diagnostics, having experience in all aspects of diagnostic operations, compliance and regulatory affairs
REYOBIQ
- Received U.S. FDA agreement for the brand name REYOBIQ (Rhenium Re186 Obisbemeda) for the Company’s lead radiotherapeutic
- Published Phase 1 clinical trial results for REYOBIQ in the peer-reviewed publication Nature Communications, demonstrating safety and potential efficacy in treating recurrent glioblastoma (GBM), with patients receiving a radiation dose >100 Gy achieving a median overall survival of 17 months, more than double the standard of care. Additional details can be found here
- Granted U.S. FDA Orphan Drug Designation for REYOBIQ for the treatment of LM in patients with lung cancer
- Completed ReSPECT-LM Phase 1 single dose administration trial and determined the maximum feasible and recommended Phase 2 doses. Additional details can be found here
- Presented positive ReSPECT-LM Phase 1 interim data for LM at the 2024 SNO Annual Conference. Additional details can be found here
- Presented positive ReSPECT-LM Phase 1 interim data for breast cancer patients with LM at the 2024 San Antonio Breast Cancer Symposium. Additional details can be found here
- Expanded strategic agreement with Telix IsoTherapeutics Group, securing a reliable supply of cGMP Rhenium-186 for late-stage clinical trials and future commercialization of REYOBIQ. Additional details can be found here
CNSide
- Presented positive FORESEE clinical trial summary demonstrating utility of the CNSide Cerebrospinal Fluid Assay Platform (“CNSide”) in diagnosis and clinical management of patients with LM. Additional details can be found here
- Presented real world, multi-institutional, longitudinal data showing the commercial utility of CNSide at the 2024 Society for Neuro-Oncology Annual Meeting. Additional details can be found here
UPCOMING EXPECTED EVENTS AND MILESTONES
- Full commercial launch of CNSide on track for 2025
- Presentations planned for the following upcoming medical conferences:
- Nuclear Medicine and Neuro-Oncology Symposium (NMN) in Vienna, Austria (May 9-10, 2025); Title: “Diagnostic and Therapeutic Innovations in the Era of Precision Medicine – Nuclear Medicine Meets Neuro-Oncology” on May 9, 2025 by Dr. Andrew Brenner, M.D, Ph.D.
- Society for Neuro-Oncology/American Society of Clinical Oncology (SNO/ASCO) CNS Metastases Conference in Baltimore, Maryland (August 14-16, 2025): Corporate Key Opinion Leader symposium, title to be determined
- Complete enrollment of Cohort 1 in the ReSPECT-LM Phase 1 multiple dose administration trial in 2025
- Complete end of Phase 1 meeting with the U.S. FDA for the ReSPECT-LM trial and determine next clinical steps in 2025
- Complete ReSPECT-GBM Phase 2 enrollment in 2025
- Obtain IND approval for the ReSPECT-PBC Phase 1/2 trial of REYOBIQ for pediatric ependymoma and high-grade glioma in H2 2025
FULL YEAR 2024 FINANCIAL RESULTS
- The Company’s cash and investments balance was
$3.6 million at December 31, 2024 compared to$8.6 million at December 31, 2023. - The Company recognized
$5.8 million in grant revenue in the year ending December 31, 2024 and$4.9 million for the year ending December 31, 2023, which in both periods represents CPRIT’s share of the costs incurred for REYOBIQ development for the treatment of patients with LM - Total operating loss for the year ending December 31, 2024 was
$14.7 million versus$13.3 million for the year ending December 31, 2023. The increase is primarily due to increased expenditures related to the ReSPECT-LM trial - Net loss for the year ending December 31, 2024 was
$13.0 million , or$(1.95) per basic share versus$13.3 million , or$(4.24) per basic share, for the year ending December 31, 2023
FOURTH QUARTER & FULL YEAR 2024 RESULTS CONFERENCE CALL
The Company will hold a conference call and live audio webcast at 5:00 pm Eastern Time today to discuss its financial results and provide a general business update.
The live audio webcast will be available at ir.plustherapeutics.com/events.
Participants may also pre-register any time before the call here. Once registration is completed, participants will be provided a dial-in number with a personalized conference code to access the call. Please dial in 15 minutes prior to the start time.
Following the live call, a replay will be available on the Company’s website under the ‘For Investors’ section. The webcast will be available on the Company’s website for 90 days following the live call.
About Plus Therapeutics
Headquartered in Houston, Texas, Plus Therapeutics, Inc. is a clinical-stage pharmaceutical company developing targeted radiotherapeutics for difficult-to-treat cancers of the central nervous system with the potential to enhance clinical outcomes. Combining image-guided local beta radiation and targeted drug delivery approaches, the Company is advancing a pipeline of product candidates with lead programs in leptomeningeal metastases (LM) and recurrent glioblastoma (GBM). The Company has built a supply chain through strategic partnerships that enable the development, manufacturing, and future potential commercialization of its products. For more information, visit https://plustherapeutics.com/.
About CNSide Diagnostic, LLC
CNSide Diagnostics, LLC is a wholly owned subsidiary of Plus Therapeutics, Inc. that develops and commercializes proprietary laboratory-developed tests, such as CNSide™, designed to identify tumor cells that have metastasized to the central nervous system in patients with carcinomas and melanomas. The CNSide™ CSF Assay Platform enables quantitative analysis and molecular characterization of tumor cells and circulating tumor DNA in the cerebrospinal fluid that inform and improve the management of patients with leptomeningeal metastases. The Company is planning to commercialize CNSide™ in the U.S. in 2025.
Cautionary Statement Regarding Forward-Looking Statements
This press release contains statements that may be deemed “forward-looking statements” within the meaning of U.S. securities laws, including without limitation, statements under the heading Upcoming Expected Events and Milestones, and statements regarding the following: the potential promise of REYOBIQ™; expectations as to the Company’s future performance, including the next steps in developing the Company’s product candidates; the Company’s clinical trials, including statements regarding the timing and characteristics of the ReSPECT-GBM, ReSPECT-LM and ReSPECT-PBC clinical trials; the continued evaluation of REYOBIQ™ including through evaluations in additional patient cohorts; and development and commercialization plans for the CNSide diagnostic platform. All statements in this press release other than statements of historical fact are forward-looking statements. These forward-looking statements may be identified by future verbs, as well as terms such as “expect” “potential,” “anticipating,” “planning” and similar expressions or the negatives thereof. Such statements are based upon certain assumptions and assessments made by management in light of their experience and their perception of historical trends, current conditions, expected future developments and other factors they believe to be appropriate.
These statements include, without limitation, statements under the heading Upcoming Events and Expected Milestones, and statements regarding the following: the potential promise of REYOBIQ; expectations as to the Company’s future performance, including the next steps in developing the Company’s product candidates; the Company’s clinical trials, including statements regarding the timing and characteristics of the ReSPECT-GBM, ReSPECT-LM and ReSPECT-PBC clinical trials; the continued evaluation of REYOBIQ including through evaluations in additional patient cohorts; development, utility, and commercial launch of the CNSide Cerebrospinal Fluid Assay Platform.
The forward-looking statements included in this press release could differ materially from those expressed or implied by these forward-looking statements because of risks, uncertainties, and other factors that include, but are not limited to, the following: the early stage of the Company’s product candidates and therapies; the results of the Company’s research and development activities, including uncertainties relating to the clinical trials of its product candidates and therapies; the Company’s liquidity and capital resources and its ability to raise additional cash; the outcome of the Company’s partnering/licensing efforts, risks associated with laws or regulatory requirements applicable to it, including the ability of the Company to remain in compliance with The Nasdaq Capital Market listing requirements; market conditions, product performance, litigation or potential litigation, and competition within the cancer diagnostics and therapeutics field; ability to develop and protect proprietary intellectual property or obtain licenses to intellectual property developed by others on commercially reasonable and competitive terms; challenges associated with radiotherapeutic manufacturing, production and distribution capabilities necessary to support the Company’s clinical trials and any commercial level product demand; and material security breach or cybersecurity attack affecting the Company’s operations or property. This list of risks, uncertainties, and other factors is not complete. Plus Therapeutics discusses some of these matters more fully, as well as certain risk factors that could affect Plus Therapeutics’ business, financial condition, results of operations, and prospects, in its reports filed with the SEC, including Plus Therapeutics’ annual report on Form 10-K for the fiscal year ended December 31, 2024, quarterly reports on Form 10-Q, and current reports on Form 8-K. These filings are available for review through the SEC’s website at www.sec.gov. Any or all forward-looking statements Plus Therapeutics makes may turn out to be wrong and can be affected by inaccurate assumptions Plus Therapeutics might make or by known or unknown risks, uncertainties, and other factors, including those identified in this press release. Accordingly, you should not place undue reliance on the forward-looking statements made in this press release, which speak only as of its date. The Company assumes no responsibility to update or revise any forward-looking statements to reflect events, trends or circumstances after the date they are made unless the Company has an obligation under U.S. federal securities laws to do so.
Investor Contact
CORE IR
investor@plustherapeutics.com
PLUS THERAPEUTICS, INC. CONSOLIDATED BALANCE SHEETS (in thousands, except share and par value data) | |||||||
As of December 31, | |||||||
2024 | 2023 | ||||||
Assets | |||||||
Current assets: | |||||||
Cash and cash equivalents | $ | 76 | $ | 8,554 | |||
Investments | 3,530 | — | |||||
Grant receivable | 571 | — | |||||
Other current assets | 1,082 | 1,280 | |||||
Total current assets | 5,259 | 9,834 | |||||
Property and equipment, net | 448 | 906 | |||||
Operating lease right-of-use assets | 73 | 202 | |||||
Goodwill | 372 | 372 | |||||
Intangible assets, net | 469 | 42 | |||||
Other assets | 12 | 32 | |||||
Total assets | $ | 6,633 | $ | 11,388 | |||
Liabilities and Stockholders’ Equity (Deficit) | |||||||
Current liabilities: | |||||||
Accounts payable and accrued expenses | $ | 11,288 | $ | 6,631 | |||
Operating lease liability | 44 | 120 | |||||
Deferred grant liability | 927 | — | |||||
Line of credit | 3,292 | — | |||||
Term loan obligation, current | — | 3,976 | |||||
Total current liabilities | 15,551 | 10,727 | |||||
Noncurrent operating lease liability | 31 | 85 | |||||
Deferred grant liability | — | 1,924 | |||||
Total liabilities | 15,582 | 12,736 | |||||
Stockholders’ equity (deficit): | |||||||
Preferred stock, | — | — | |||||
Common stock, | 6 | 5 | |||||
Treasury stock (at cost, 258,425 and 78,559 shares as of December 31, 2024 and 2023, respectively) | (500 | ) | (126 | ) | |||
Additional paid-in capital | 485,024 | 479,274 | |||||
Accumulated deficit | (493,479 | ) | (480,501 | ) | |||
Total stockholders’ equity (deficit) | (8,949 | ) | (1,348 | ) | |||
Total liabilities and stockholders’ equity (deficit) | $ | 6,633 | $ | 11,388 |
PLUS THERAPEUTICS, INC. CONSOLIDATED STATEMENTS OF OPERATIONS (in thousands, except share and per share data) | |||||||
For the Years Ended December 31, | |||||||
2024 | 2023 | ||||||
Grant revenue | $ | 5,824 | $ | 4,913 | |||
Operating expenses: | |||||||
Research and development | 10,580 | 9,690 | |||||
General and administrative | 9,939 | 8,544 | |||||
Total operating expenses | 20,519 | 18,234 | |||||
Operating loss | (14,695 | ) | (13,321 | ) | |||
Other income (expense): | |||||||
Financing expense | (3,545 | ) | — | ||||
Change in fair value of warrants | 5,654 | — | |||||
Warrant issuance costs | (486 | ) | — | ||||
Interest income | 273 | 400 | |||||
Interest expense | (179 | ) | (395 | ) | |||
Total other income | 1,717 | 5 | |||||
Net loss | $ | (12,978 | ) | $ | (13,316 | ) | |
Per share information: | |||||||
Net loss per share of common stock - basic | $ | (1.95 | ) | $ | (4.24 | ) | |
Weighted average number of shares of common stock outstanding - basic | 6,640,251 | 3,140,925 | |||||
Net loss per share of common stock - diluted | $ | (2.34 | ) | $ | (4.24 | ) | |
Weighted average number of shares of common stock outstanding - diluted | 7,700,774 | 3,140,925 |
PLUS THERAPEUTICS, INC. CONSOLIDATED STATEMENTS OF CASH FLOWS (in thousands) | |||||||
For the Years Ended December 31, | |||||||
2024 | 2023 | ||||||
Cash flows used in operating activities: | |||||||
Net loss | $ | (12,978 | ) | $ | (13,316 | ) | |
Adjustments to reconcile net loss to net cash used in operating activities: | |||||||
Depreciation and amortization | 723 | 628 | |||||
Amortization of deferred financing costs and debt discount | 20 | 190 | |||||
Common stock issued for research and development | — | 75 | |||||
Accretion of discount on short-term investments | (111 | ) | — | ||||
Non-cash financing expenses | 3,545 | — | |||||
Change in fair value of warrants | (5,654 | ) | — | ||||
Loss on disposal of property and equipment | — | 2 | |||||
Share-based compensation expense | 550 | 569 | |||||
Reduction in the carrying amount of operating lease right-of-use assets | 129 | 117 | |||||
Increases (decreases) in cash caused by changes in operating assets and liabilities: | |||||||
Grant receivable | (571 | ) | — | ||||
Other assets | 218 | 2,397 | |||||
Accounts payable and accrued expenses | 4,702 | (3,677 | ) | ||||
Change in operating lease liabilities | (130 | ) | (117 | ) | |||
Deferred grant liability | (997 | ) | 281 | ||||
Net cash used in operating activities | (10,554 | ) | (12,851 | ) | |||
Cash flows used in investing activities: | |||||||
Purchases of property and equipment | (146 | ) | (160 | ) | |||
Purchases of intangible assets | (545 | ) | — | ||||
Purchases of short-term investments | (15,590 | ) | — | ||||
Redemption of short-term investments | 12,170 | — | |||||
Net cash used in investing activities | (4,111 | ) | (160 | ) | |||
Cash flows from financing activities: | |||||||
Principal payments of long-term obligations | (3,996 | ) | (1,608 | ) | |||
Proceeds from credit facility | 3,292 | — | |||||
Proceeds from sale of common stock warrants, and pre-funded warrants, net | 7,265 | — | |||||
Proceeds from sale of common stock, net of offering costs of | — | 5,527 | |||||
Payment of offering costs related to sale of common stock | — | (348 | ) | ||||
Purchase of treasury stock | (374 | ) | (126 | ) | |||
Net cash provided by financing activities | 6,187 | 3,445 | |||||
Net decrease in cash and cash equivalents | (8,478 | ) | (9,566 | ) | |||
Cash and cash equivalents at beginning of period | 8,554 | 18,120 | |||||
Cash and cash equivalents at end of period | $ | 76 | $ | 8,554 | |||
