Welcome to our dedicated page for PureTech Health plc American Depositary Shares news (Ticker: PRTC), a resource for investors and traders seeking the latest updates and insights on PureTech Health plc American Depositary Shares stock.
PureTech Health plc (symbol: PRTC) is a cutting-edge biotechnology company committed to developing and commercializing innovative medicines that address serious diseases. Headquartered in Boston, Massachusetts, PureTech Health specializes in modulating the adaptive human system to create transformative treatments.
The company's core business is focused on discovering and advancing highly differentiated medicines aimed at a wide range of devastating conditions. These include inflammatory, fibrotic, and immunological diseases, as well as intractable cancers, lymphatic and gastrointestinal disorders, and neurological and neuropsychological issues. PureTech Health operates through three key segments: Wholly-Owned Programs, Controlled Founded Entities, and Parent Companies & Others.
Recent Achievements
PureTech Health boasts a robust pipeline of advanced programs that are at the post-human proof of concept stage, targeting some of the most pressing healthcare needs globally. The company's innovative approach has resulted in numerous partnerships and collaborations with leading research institutions and other biopharma entities.
Current Projects
Currently, PureTech Health is involved in several groundbreaking projects aimed at developing treatments that can significantly improve patient outcomes. These projects leverage the company's expertise in modulating the adaptive human system to create therapies that are not only effective but also highly differentiated from existing treatments.
Financial Condition
PureTech Health's financial condition remains strong, supported by a diverse portfolio of wholly-owned programs and controlled founded entities. The company's strategic investments and collaborations have positioned it well to continue driving innovation in the biopharma space.
Partnerships and Collaborations
Collaboration is at the heart of PureTech Health's strategy. The company has established numerous partnerships with top-tier research institutions and other biopharma companies to accelerate the development and commercialization of its innovative therapies.
Products
PureTech Health's product portfolio includes a range of medicines designed to address some of the most challenging diseases. These products are developed with a focus on significantly improving the quality of life for patients.
PureTech Health's Founded Entity, Gelesis, has completed a business combination with Capstar Special Purpose Acquisition Corp. Gelesis will begin trading on the New York Stock Exchange under the ticker symbol 'GLS' on January 14, 2022, after securing approximately $105 million in gross proceeds. These funds will primarily support the national launch of Plenity, an FDA-cleared weight management product. With 71 million Americans having gained weight during the pandemic, Gelesis aims to address the rising demand for effective weight management solutions.
PureTech Health plc, a clinical-stage biotherapeutics company, announced that Daphne Zohar, the CEO, will present at the 40th Annual J.P. Morgan Healthcare Conference on January 12, 2022, at 7:30am EST. The company focuses on developing innovative medicines for severe diseases, including inflammatory and neuropsychological disorders. PureTech has a robust pipeline of 25 therapeutic candidates, with two receiving FDA and European marketing approvals. A webcast of the presentation will be available on their investor site.
PureTech Health plc (Nasdaq: PRTC, LSE: PRTC) announced plans to initiate registration-enabling studies for LYT-100, targeting idiopathic pulmonary fibrosis (IPF) through a 505(b)(2) pathway. This includes a dose-ranging study and a Phase 3 study. Recent results show that LYT-100 led to a 50% reduction in gastrointestinal adverse events compared to pirfenidone, the current standard treatment. Additionally, Dr. Paul Ford joins as SVP of Clinical Development to lead LYT-100's advancement, emphasizing the potential for improved tolerability and treatment adherence for IPF patients.
PureTech Health reported significant advancements in its clinical-stage therapeutic candidates across various indications. Key highlights include the progress of LYT-100 in Phase 2 trials for conditions related to inflammation and fibrosis, and the initiation of Phase 1 trials for LYT-200 and LYT-300. The company also noted successful scaling and launch preparations for its Founded Entities, including Gelesis’ Plenity®. The upcoming year is expected to be catalyst-rich with multiple study results promising to impact serious diseases. PureTech continues its commitment to innovative medicine, enhancing shareholder value.
PureTech Health plc presented preclinical proof-of-concept data for LYT-300 at the 60th American College of Neuropsychopharmacology Annual Meeting. LYT-300, an oral allopregnanolone, aims to treat neurological disorders such as depression and anxiety. The data show systemic exposure achieved after oral administration, enhancing the therapeutic potential of the Glyph™ technology platform. LYT-300 has advanced into a Phase 1 clinical study to assess safety and tolerability, with results expected in the second half of 2022.
PureTech Health plc has initiated a Phase 1 clinical study of LYT-300, an oral therapeutic candidate aimed at treating various neurological and neuropsychological conditions such as depression and anxiety. Leveraging the Glyph technology platform, LYT-300 is designed to enhance oral bioavailability compared to natural allopregnanolone, which suffers from poor absorption. The study will assess safety, tolerability, and pharmacokinetics, with results expected in the second half of 2022, potentially guiding future trials for broader indications.
PureTech Health announces the launch of Plenity, an FDA-cleared weight management aid, now available across the United States. The company also appointed Joy Bauer as Chief Nutrition Officer, who will provide nutrition counseling and education for Plenity members. Plenity is designed to help individuals manage weight by feeling satisfied with smaller portions. A subscription costs
PureTech Health's Founded Entity, Gelesis, announced a $30 million pre-order for its weight management product, Plenity®, from Ro, a leading direct-to-patient healthcare company. The new commercial manufacturing facility is now producing Plenity at scale to meet increasing demand, which has exceeded supply since its beta launch in 2020. Ro anticipates a staggering 1,500% YoY revenue growth for Plenity from December 2020 to December 2021, solidifying weight management as a top request on their platform.
PureTech Health plc announced positive results from a Phase 1 trial of LYT-100, demonstrating good tolerability and a favorable pharmacokinetic profile. The maximum tolerated dose was not reached, indicating further dose escalation studies are planned. The ongoing Phase 2 trial for Long COVID respiratory complications is on track for completion by year-end, with results expected in H1 2022. Future Phase 1 studies aim to clarify dosing and tolerability across various indications. These advancements underscore LYT-100's potential in treating inflammatory and fibrotic conditions.
PureTech Health plc (Nasdaq: PRTC, LSE: PRTC) will participate in fireside chats at two key investor conferences: Piper Sandler 33rd Annual Virtual Healthcare Conference on
Presenters include senior management members like George Farmer, Ph.D., and Daphne Zohar. Webcasts will be accessible via their investor relations page, reflecting their commitment to transparency and investor engagement.
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