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ProPhase Labs, Inc. Announces Financial Results for the Year Ended December 31, 2024

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ProPhase Labs (NASDAQ: PRPH) reported its financial results for FY2024, highlighting significant strategic restructuring. The company completed the sale of its Pharmaloz manufacturing operations for $23 million in January 2025, reducing employee headcount from 96 to 28.

Key financial results show a substantial decline, with net revenue decreasing 80.6% to $6.8 million in 2024 from $35.0 million in 2023. The company reported a net loss of $53.4 million ($2.61 per share) compared to a $16.8 million loss ($0.98 per share) in 2023.

Strategic developments include accelerating BE-Smart Esophageal Cancer test commercialization as a cash-pay diagnostic, with a target market of 7 million endoscopies annually ($7-14 billion market). The company has also restructured Nebula Genomics, now controlling a database of over 65,000 genomes, and entered a potential $50 million recovery opportunity with Crown Medical Collections.

ProPhase Labs (NASDAQ: PRPH) ha riportato i risultati finanziari per l'anno fiscale 2024, evidenziando una significativa ristrutturazione strategica. L'azienda ha completato la vendita delle operazioni di produzione Pharmaloz per 23 milioni di dollari a gennaio 2025, riducendo il numero di dipendenti da 96 a 28.

I risultati finanziari chiave mostrano un notevole declino, con ricavi netti in diminuzione dell'80,6% a 6,8 milioni di dollari nel 2024, rispetto ai 35,0 milioni di dollari del 2023. L'azienda ha riportato una perdita netta di 53,4 milioni di dollari (2,61 dollari per azione) rispetto a una perdita di 16,8 milioni di dollari (0,98 dollari per azione) nel 2023.

Gli sviluppi strategici includono l'accelerazione della commercializzazione del test diagnostico per il cancro esofageo BE-Smart come test a pagamento, con un mercato target di 7 milioni di endoscopie annuali (mercato da 7 a 14 miliardi di dollari). L'azienda ha anche ristrutturato Nebula Genomics, ora controllando un database di oltre 65.000 genomi, ed è entrata in un'opportunità di recupero potenziale di 50 milioni di dollari con Crown Medical Collections.

ProPhase Labs (NASDAQ: PRPH) informó sus resultados financieros para el año fiscal 2024, destacando una reestructuración estratégica significativa. La compañía completó la venta de sus operaciones de fabricación de Pharmaloz por 23 millones de dólares en enero de 2025, reduciendo el número de empleados de 96 a 28.

Los resultados financieros clave muestran un notable descenso, con ingresos netos que disminuyeron un 80,6% a 6,8 millones de dólares en 2024, desde 35,0 millones de dólares en 2023. La empresa reportó una pérdida neta de 53,4 millones de dólares (2,61 dólares por acción) en comparación con una pérdida de 16,8 millones de dólares (0,98 dólares por acción) en 2023.

Los desarrollos estratégicos incluyen la aceleración de la comercialización de la prueba diagnóstica para el cáncer esofágico BE-Smart como un diagnóstico de pago, con un mercado objetivo de 7 millones de endoscopias anuales (mercado de 7 a 14 mil millones de dólares). La compañía también ha reestructurado Nebula Genomics, controlando ahora una base de datos de más de 65,000 genomas, y ha entrado en una oportunidad de recuperación potencial de 50 millones de dólares con Crown Medical Collections.

프로페이즈 랩스 (NASDAQ: PRPH)는 FY2024에 대한 재무 결과를 발표하며, 중요한 전략적 구조 조정을 강조했습니다. 회사는 2025년 1월에 2300만 달러에 Pharmaloz 제조 운영을 매각하여 직원 수를 96명에서 28명으로 줄였습니다.

주요 재무 결과는 상당한 감소를 보여주며, 2024년 순매출이 2023년 3500만 달러에서 680만 달러로 80.6% 감소했습니다. 회사는 2023년 1주당 0.98달러 손실에 비해 1주당 2.61달러의 5340만 달러 순손실을 보고했습니다.

전략적 개발에는 BE-Smart 식도암 검사 상용화를 가속화하는 것이 포함되며, 이는 연간 700만 건의 내시경 검사 시장(70억~140억 달러 시장)을 목표로 하고 있습니다. 회사는 또한 65,000개 이상의 유전체 데이터베이스를 관리하는 Nebula Genomics를 재구성했으며, Crown Medical Collections과 함께 5000만 달러의 회수 기회를 모색하고 있습니다.

ProPhase Labs (NASDAQ: PRPH) a annoncé ses résultats financiers pour l'exercice 2024, mettant en avant une restructuration stratégique significative. L'entreprise a finalisé la vente de ses opérations de fabrication Pharmaloz pour 23 millions de dollars en janvier 2025, réduisant le nombre d'employés de 96 à 28.

Les résultats financiers clés montrent un déclin substantiel, avec un chiffre d'affaires net diminuant de 80,6 % pour atteindre 6,8 millions de dollars en 2024, contre 35,0 millions de dollars en 2023. L'entreprise a déclaré une perte nette de 53,4 millions de dollars (2,61 dollars par action) par rapport à une perte de 16,8 millions de dollars (0,98 dollars par action) en 2023.

Les développements stratégiques incluent l'accélération de la commercialisation du test diagnostique BE-Smart pour le cancer de l'œsophage en tant que diagnostic payant, avec un marché cible de 7 millions d'endoscopies par an (marché de 7 à 14 milliards de dollars). L'entreprise a également restructuré Nebula Genomics, contrôlant désormais une base de données de plus de 65 000 génomes, et est entrée dans une opportunité de récupération potentielle de 50 millions de dollars avec Crown Medical Collections.

ProPhase Labs (NASDAQ: PRPH) hat seine finanziellen Ergebnisse für das Geschäftsjahr 2024 veröffentlicht und eine bedeutende strategische Umstrukturierung hervorgehoben. Das Unternehmen hat im Januar 2025 den Verkauf seiner Pharmaloz-Produktionsbetriebe für 23 Millionen Dollar abgeschlossen und die Mitarbeiterzahl von 96 auf 28 reduziert.

Wichtige finanzielle Ergebnisse zeigen einen erheblichen Rückgang, wobei der Nettoumsatz 2024 um 80,6 % auf 6,8 Millionen Dollar gesunken ist, verglichen mit 35,0 Millionen Dollar im Jahr 2023. Das Unternehmen berichtete von einem Nettoverlust von 53,4 Millionen Dollar (2,61 Dollar pro Aktie) im Vergleich zu einem Verlust von 16,8 Millionen Dollar (0,98 Dollar pro Aktie) im Jahr 2023.

Strategische Entwicklungen umfassen die Beschleunigung der Kommerzialisierung des BE-Smart-Testes auf Speiseröhrenkrebs als kostenpflichtige Diagnose, mit einem Zielmarkt von 7 Millionen Endoskopien jährlich (Markt von 7 bis 14 Milliarden Dollar). Das Unternehmen hat auch Nebula Genomics umstrukturiert und kontrolliert nun eine Datenbank von über 65.000 Genomen und hat eine potenzielle Rückgewinnungsmöglichkeit von 50 Millionen Dollar mit Crown Medical Collections eingegangen.

Positive
  • Sale of Pharmaloz manufacturing division for $23 million strengthening balance sheet
  • Significant reduction in operational costs through headcount reduction from 96 to 28 employees
  • BE-Smart diagnostic platform targeting $7-14 billion annual market opportunity
  • Valuable genomics database with over 65,000 genomes across 130 countries
  • Potential $50 million non-dilutive capital from Crown Medical Collections recovery
Negative
  • Net revenue declined 80.6% to $6.8 million in 2024
  • Net loss increased to $53.4 million in 2024 from $16.8 million in 2023
  • Working capital decreased to -$1.5 million from $26.7 million year-over-year
  • Cash and cash equivalents declined to $0.7 million from $1.6 million
  • Gross margin turned negative at -2.2% compared to 44.5% in 2023

Insights

ProPhase Labs' 2024 financial results reveal a company in significant transition, with concerning financials but potentially promising strategic shifts. Revenue plummeted 80.6% to $6.8 million (from $35.0 million in 2023), primarily due to the complete elimination of COVID-19 testing services. The company reported a net loss of $53.4 million ($2.61 per share), more than triple the $16.8 million loss in 2023.

Most alarming is the deteriorating balance sheet, with cash dropping to just $0.7 million and working capital turning negative at -$1.5 million. However, the January 2025 sale of Pharmaloz manufacturing for $23 million (after the reporting period) should provide critical financial breathing room.

The workforce reduction from 96 to 28 employees represents a 70% headcount cut, dramatically reducing burn rate. The company is wisely pivoting toward higher-margin opportunities like the BE-Smart esophageal cancer diagnostic test, which targets a potential $7-14 billion market from 7 million annual endoscopies.

The $50 million potential insurance payment recovery through Crown Medical Collections could be transformative if realized in H2 2025, particularly since the company only carries $20.1 million in accounts receivable on its books.

While the immediate financial situation appears precarious, ProPhase has made decisive moves to streamline operations, eliminate underperforming segments, and focus on higher-potential assets. The effectiveness of this restructuring and the success of BE-Smart commercialization will determine whether this radical transformation can reverse the company's financial decline.

ProPhase's strategic pivot toward its BE-Smart Esophageal Cancer test represents a calculated bet on a potential breakthrough diagnostic. The test offers several clinical advantages - requiring just 1-2 biopsy tissue slices while providing disease severity assessment and progression prediction capabilities that exceed traditional methods.

The company's decision to initially launch BE-Smart as a cash-pay diagnostic follows a proven pathway used by other successful diagnostic companies like Castle Biosciences. This approach allows immediate market entry while pursuing more complex CPT coding and reimbursement channels.

The involvement of Dr. Joe Abdo (co-inventor) and GI pathology expert Dr. Christopher Hartley from Mayo Clinic adds scientific credibility. The pending publication of performance metrics in a peer-reviewed manuscript within 8-16 weeks will be crucial for clinical adoption.

What truly distinguishes BE-Smart is its proprietary multiplexing capability and exclusive IP on eight protein markers associated with disease progression to esophageal adenocarcinoma. These markers provide unique insights from tissue samples - a significant advantage over competing assays that require larger specimens.

The genomics database of 65,000 whole genomes across 130 countries represents an undervalued asset with potential applications in research partnerships, drug development, and diagnostic innovation. Unlike ancestry tests analyzing less than 1% of the genome, ProPhase's platform examines nearly 100%, creating a substantially more valuable dataset.

While promising, the BE-Smart commercialization faces significant execution challenges - particularly establishing clinical adoption patterns, navigating the complex reimbursement landscape, and competing against entrenched diagnostic providers. The timeline from regulatory clearance to meaningful revenue remains uncertain.

Company to Accelerate BE-Smart Commercialization as a Cash-Pay Diagnostic

Significantly reduces overhead, improves margins heading into Q2 2025

Company to hold a conference call Monday, March 31, 2025, at 11:00 AM EST

GARDEN CITY, NY, March 31, 2025 (GLOBE NEWSWIRE) -- ProPhase Labs, Inc. (NASDAQ: PRPH), (the “Company” or “ProPhase”), a next generation biotech, genomics and consumer products company, today reported its financial and operational results for the full-year ended December 31, 2024 and outlined strategic corporate developments aimed at realigning the Company for sustained long-term growth, profitability, and strategic focus.

Ted Karkus, CEO of ProPhase Labs, will present to shareholders today, March 31, 2025, at 11:00 a.m. EST during the live Virtual Non-Deal Roadshow Series. The details are available below.

Following a year of operational reevaluation and bold decision-making, ProPhase has emerged with a significantly leaner structure, stronger balance sheet, and a renewed commitment to its core growth assets, including BE-Smart Esophageal Cancer test, Nebula Genomics/DNA Complete (with its proprietary genomic database) and its dietary supplements business.

Key Financial Milestone: Manufacturing Division Sold for $23 Million

In January 2025, the Company completed the divestiture of its Pharmaloz manufacturing operations for approximately $23 million. ProPhase views the transaction as a significant achievement as the sale enhanced financial flexibility by significantly reducing debt, eliminating payables, and strengthening the overall balance sheet. In combination with shutting down the Company’s genomics laboratory, employee headcount has been reduced from 96 employees in December 2024 to 28 employees currently. IT costs have also significantly decreased heading into Q2 2025. These moves remove a layer of operational risk that allow the Company to focus on higher-margin, forward-facing businesses.

BE-Smart Diagnostic Platform Launch

The Company has engaged Dr. Joe Abdo, former CEO of Stella Diagnostics and co-inventor of BE-Smart, in collaboration with our other consultants, to begin the commercialization of its high-performance assay for detection of esophageal diseases as a clinically available diagnostic test. BE-Smart is designed to deliver high accuracy using only 1–2 slices of biopsy tissue and can identify disease severity while also being predictive of progression, surpassing traditional diagnostics both in performance and utility.

Dr. Abdo is working alongside GI pathology expert Dr. Christopher Hartley, who leads the validation study at Mayo Clinic for BE-Smart. They, along with key stakeholders from multiple academic and clinical institutions, have presented compelling data nationwide and are currently preparing a peer-reviewed manuscript for publication to highlight the performance of BE-Smart.

The Company’s efforts are focused on producing a new manuscript that is currently in preparation that will provide a comprehensive overview of BE-Smart’s performance metrics. The manuscript is estimated to be submitted for peer-review within 4 to 8 weeks. We anticipate an additional 4 to 8 weeks for a decision on publication, following submission. Once published, this manuscript will reinforce the test’s efficacy and its advantages over existing diagnostics, further establishing its value to gastroenterologists and patients.

During the manuscript review and publication process, the Company will begin working on the next steps for commercialization. This includes exploring existing generic CPT codes to identify potential developmental paths for bringing BE-Smart to market. Similar to other diagnostic tests in the industry like Castle Biosciences’s TissueCypher, BE-Smart is expected to be launched initially as a cash-pay diagnostic for gastroenterologists while CPT coding is pursued. This will allow patients the choice for optimized esophageal screening with what the Company believes is the state-of-the-art diagnostic test. Despite the possibility of initial non-payment, this strategy will help initiate reimbursement discussions and increase the volume of tests ordered. Doctors can be assured that neither patients nor their clinics will face balance billing, ensuring a patient-friendly approach. Additionally, the Company will leverage our extensive network of key opinion leaders to connect with GI doctors and drive the promotion and adoption of the test at high impact conferences.

The Company believes that some competing assays in the space do not have the unique multiplexablility of BE-Smart, which allows for detection of many significant disease progressors from very little tissue. Availability of these small biopsies remains a significant limitation with outsourced testing which limits the success of other diagnostic tests. BE-Smart is also the only assay to have the IP on eight key protein markers that are expressed in diseases of the foregut and have been associated with disease progression, specifically into esophageal adenocarcinoma. Other cash based esophageal cancer diagnostic tests have had significant success recently even though they require a large amount of tissue and cannot see our proprietary and highly informative markers. This highlights the potential for BE-Smart. The target market for BE-Smart is approximately 7 million endoscopies, in the U.S. alone, that are performed on patients at higher risk each year. This equates to a $7 - $14 billion annual target market for BE-Smart.

Nebula Genomics Overhaul & Strategic Review

ProPhase’s wholly-owned subsidiary Nebula Genomics, under new leadership from Jason Karkus, has been strategically restructured. Following the lab shutdown, the division has formed partnerships with multiple external genomic sequencing labs, each competing to deliver superior pricing and quality. As part of these efforts, and in coordination with recently-hired Stu Hollenshead as COO, the Company has significantly reduced IT and data expenses, streamlined payroll, and eliminated substantial ongoing operational costs. These cost-effective strategies have drastically improved margins, enhanced cash flow, and reduced execution risk. Additionally, the Company’s direct-to-consumer platform, DNA Complete, has been refined and positioned for growth. Under the guidance of Stu Hollenshead, targeted advertising campaigns are expected to significantly ramp up revenues and profitability for this subsidiary.

In parallel, the Company is exploring a potential sale of Nebula Genomics and is in the early stages of evaluating strategic options.

Nebula Genomics Genomic Database

ProPhase now controls a database of over 65,000 genomes across 130 countries and is actively growing. This is equivalent in scientific depth to over 150 million ancestry tests. While most consumer DNA ancestry tests analyze less than 1% of the genome, ProPhase’s platform analyzes nearly 100%, creating unique insights and opportunities. The Company believes this database holds significant value in addition to the Nebula and DNA Complete businesses themselves.

$50 Million Opportunity with Crown Medical Collections

ProPhase has entered into a new revenue initiative with Crown Medical Collections. Crown estimates the recovery of approximately $50 million in insurance payments, net of contingency fees, on behalf of ProPhase. If Crown’s efforts succeed, this could serve as a significant, non-dilutive financial influx in the second half of 2025 to support strategic development of ProPhase’s core businesses. Notably, the Company currently carries only $20.1 million total accounts receivable, net on its financials.

A Unified Future: Supplements, Telehealth, and Cross-Sell Synergies

With infrastructure now in place across DNA Complete, BE-Smart, and ProPhase’s dietary supplement line, the Company is considering the launch of an integrated telehealth initiative. Several early-stage companies have approached ProPhase, and discussions are underway to leverage these partnerships and cross-sell its suite of health and genomic services.

Financial Results

December 31, 2024 compared with December 31, 2023

Net revenue for the year ended December 31, 2024, decreased $28.2 million, or 80.6%, to $6.8 million compared to $35.0 million for the year ended December 31, 2023. The decrease in net revenue was the result of an $24.8 million decrease from diagnostic services, and a $3.4 million decrease from consumer products. The decrease in net revenue for diagnostic services was due to decreased COVID-19 testing volumes compared to the 2023 period. Overall diagnostic testing volume decreased from approximately 480,000 tests for the year ended December 31, 2023 to approximately zero tests for the year ended December 31, 2024.

Cost of revenues for the year ended December 31, 2024 was $6.9 million, comprised of $2.3 million for diagnostic services and $4.6 million for consumer products. Cost of revenues for the year ended December 31, 2023 were $19.4 million comprised of $11.8 million for diagnostic services and $7.6 million for consumer products.

We realized a gross loss of $0.2 million for the year ended December 31, 2024, as compared to a gross profit of $15.6 million for the year ended December 31, 2023. The decrease of $15.7 million was comprised of a decrease of $15.4 million in diagnostic services, partially offset by an increase of $0.3 million in consumer products. For the year ended December 31, 2024 and 2023 we realized an overall gross margin of (2.2)% and 44.5%, respectively. Gross margin for diagnostic services was —% and 52.6% for the year ended December 31, 2024 and 2023, respectively. Gross margin for consumer products was 32.2% and 24.6% for the year ended December 31, 2024 and 2023, respectively. Gross margin for consumer products have historically been influenced by fluctuations in quarter-to-quarter production volume, fixed production costs and related overhead absorption, raw ingredient costs, inventory mark to market write-downs and timing of shipments to customers.

Diagnostic expenses for the year ended December 31, 2024 were zero as compared to $1.9 million of diagnostic expenses for the year ended December 31, 2023. The decrease in diagnostic expenses of $1.9 million was primarily due to was due to decreased COVID-19 testing volumes for the year ended December 31, 2024 compared to the year ended December 31, 2023 as a result of the Omicron variant, which emerged in early 2022.

General and administration expenses increased $4.4 million for the year ended December 31, 2024 to $37.9 million, as compared to $33.4 million for the year ended December 31, 2023. The increase in general and administration expenses for the year ended December 31, 2024 as compared to the year ended December 31, 2023 was related to costs to run our genomics operations, and marketing and professional fees associated with the Company's strategic initiatives.

Research and development costs for the year ended December 31, 2024 and 2023 were $0.6 million and $1.4 million, respectively. The decrease in research and development costs for the year ended December 31, 2024 as compared to the year ended December 31, 2023 was principally due to less, and the completion of certain studies. Research and development activities include product research and field testing.

As a result of the effects described above, net loss for the year ended December 31, 2024 was $53.4 million, or $(2.61) per share, as compared to a net loss of $16.8 million, or $(0.98) per share, for the year ended December 31, 2023. Diluted net loss per share for the years ended December 31, 2024 and 2023 were $(2.61) and $(0.98), respectively.

Our aggregate cash and cash equivalents as of December 31, 2024 were $0.7 million as compared to $1.6 million at December 31, 2023. Our working capital was $(1.5) million and $26.7 million as of December 31, 2024 and 2023, respectively. The decrease of $0.9 million in our cash and cash equivalents for the year ended December 31, 2024 was primarily due to cash used in operating activities and capital expenditures of $0.9 million.

Webcast Details
Investors interested in participating in this live event will need to register using the link below. After the event, a replay will be available on the Company’s investor website.

REGISTER HERE:
https://www.renmarkfinancial.com/events/fourth-quarter-year-end-2024-results-virtual-conference-call-nasdaq-prph-PA3S8FxovQ

  • To ensure smooth connectivity, please access this link using the latest version of Google Chrome.

About ProPhase Labs

ProPhase Labs Inc. (Nasdaq: PRPH) (“ProPhase”) is a next-generation biotech, genomics and consumer products company. Our goal is to create a healthier world with bold action and the power of insight. We’re revolutionizing healthcare with industry-leading Whole Genome Sequencing solutions, while developing potential game changer diagnostics and therapeutics in the fight against cancer. This includes a potentially life-saving cancer test focused on early detection of esophageal cancer and potential breakthrough cancer therapeutics with novel mechanisms of action. We develop, manufacture, and commercialize health and wellness solutions to enable people to live their best lives. We are committed to executional excellence, smart diversification, and a synergistic, omni-channel approach. ProPhase Labs’ valuable subsidiaries, their synergies, and significant growth underscore our potential for long-term value.

Forward-Looking Statements

Except for the historical information contained herein, this document contains forward looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including statements regarding our strategy, plans, objectives and initiatives, including our expectations regarding the future revenue growth potential of each of our subsidiaries, our expected timeline for commercializing our BE-Smart Esophageal Cancer Test, our expectations regarding future liquidity events, the success of our efforts to collect accounts receivables and anticipated timeline for any payments relating thereto, and our ability to successfully transition into a consumer products company. Management believes that these forward-looking statements are reasonable as and when made. However, such forward-looking statements involve known and unknown risks, uncertainties, and other factors that may cause actual results to differ materially from those projected in the forward-looking statements. These risks and uncertainties include but are not limited to our ability to obtain and maintain necessary regulatory approvals, general economic conditions, consumer demand for our products and services, challenges relating to entering into and growing new business lines, the competitive environment, and the risk factors listed from time to time in our Annual Reports on Form 10-K, Quarterly Reports on Form 10-Q and any other SEC filings. The Company undertakes no obligation to update forward-looking statements except as required by applicable securities laws. Readers are cautioned that forward-looking statements are not guarantees of future performance and are cautioned not to place undue reliance on any forward-looking statements.

Media Relations and Institutional Investor Contact:
ProPhase Labs, Inc.
investorrelations@prophaselabs.com

Retail Investor Relations Contact:
Renmark Financial Communications
John Boidman
212-812-7680
Jboidman@renmarkfinancial.com

PROPHASE LABS, INC AND SUBSIDIARIES
CONSOLIDATED BALANCE SHEETS
(in thousands, except share and per share amounts)

  December 31,
2024
  December 31,
2023
 
ASSETS        
Current assets        
Cash and cash equivalents $678  $1,609 
Marketable securities, available for sale     3,127 
Accounts receivable, net  20,058   35,814 
Inventory, net  1,143   2,291 
Prepaid expenses and other current assets  2,615   1,955 
Current assets held-for-sale  6,143   2,789 
Total current assets  30,637   47,585 
         
Property, plant and equipment, net  7,501   10,330 
Prepaid expenses, net of current portion  217   832 
Operating lease right-of-use asset, net  4,115   4,572 
Intangible assets, net  9,750   12,333 
Goodwill  5,231   5,231 
Deferred tax asset     7,313 
Other assets  310   1,163 
Non-current assets held-for-sale  5,439   2,568 
TOTAL ASSETS $63,200  $91,927 
         
LIABILITIES AND STOCKHOLDERS’ EQUITY        
Current liabilities        
Accounts payable $13,717  $8,644 
Accrued diagnostic services  31   314 
Accrued advertising and other allowances  151   24 
Finance lease liabilities  2,147   1,840 
Operating lease liabilities  1,214   953 
Short-term loan payable, net of discount of $237  3,207    
Deferred revenue  1,698   2,382 
Income tax payable  1,987   3,279 
Other current liabilities  2,115   2,586 
Current liabilities held-for-sale  5,867   835 
Total current liabilities  32,134   20,857 


PROPHASE LABS, INC AND SUBSIDIARIES
CONSOLIDATED BALANCE SHEETS
(in thousands, except share and per share amounts)
Continued

  December 31,
2024
  December 31,
2023
 
       
Non-current liabilities:        
Unsecured promissory notes, net of discount of $127 and $266 $9,873  $7,334 
Unsecured long-term debt, net of discount of $423  1,779    
Due to sellers (see Note 3)  2,000   2,000 
Deferred revenue, net of current portion  784   1,100 
Finance lease liabilities, net of current portion  2,591   4,092 
Operating lease liabilities, net of current portion  3,762   4,237 
Non-current liabilities held-for-sale  2,924   2,924 
Total non-current liabilities  23,713   21,687 
Total liabilities  55,847   42,544 
         
COMMITMENTS AND CONTINGENCIES        
         
Stockholders’ equity        
Preferred stock authorized 1,000,000, $0.0005 par value, no shares issued and outstanding      
Common stock authorized 50,000,000, $0.0005 par value, 29,874,029 and 18,045,029 shares outstanding, respectively  23   18 
Additional paid-in capital  129,921   118,694 
Accumulated deficit  (58,393)  (5,029)
Treasury stock, at cost, 12,940,967 and 18,940,967 shares, respectively  (64,000)  (64,000)
Accumulated other comprehensive loss  (198)  (300)
Total stockholders’ equity  7,353   49,383 
TOTAL LIABILITIES AND STOCKHOLDERS’ EQUITY $63,200  $91,927 


PROPHASE LABS, INC & SUBSIDIARIES

CONSOLIDATED STATEMENTS OF CASH FLOWS
(in thousands)

  For the years ended 
  December 31, 2024  December 31, 2023 
Cash flows from operating activities        
 Net loss $(53,364) $(16,782)
 Less: loss from discontinued operations, net of tax  (3,839)  (402)
 Net loss from continuing operations  (49,525)  (16,380)
Adjustments to reconcile net loss to net cash provided by (used in) operating activities:        
Realized loss on marketable debt securities  18   (22)
Depreciation and amortization  6,187   6,050 
Amortization of debt discount  1,485   132 
Amortization on right-of-use assets  457   421 
Gain from disposal of fixed assets  (91)  (23)
Stock-based compensation expense  3,638   3,536 
Accounts receivable allowances     724 
Inventory valuation reserve  (212)   
Credit loss expense, direct write-offs  11,018   91 
Debt extinguishment loss  333    
Changes in operating assets and liabilities:        
Accounts receivable  4,738   (617)
Inventory  1,360   170 
Prepaid expenses and other current assets  (45)  (216)
Deferred tax asset  7,150   (7,313)
Other assets  853    
Accounts payable and accrued expenses  5,066   2,862 
Accrued diagnostic services  (283)  (695)
Accrued advertising and other allowances  127   (75)
Deferred revenue  (1,000)  (76)
Deferred tax liability     (307)
Lease liabilities  (1,408)  (181)
Income taxes payable  (1,292)  (911)
Other liabilities  (377)  637 
 Net cash used in operating activities - continuing operations  (11,803)  (12,193)
 Net cash (used in) provided by operating activities - discontinued operations  (5,735)  305 
 Net cash used in operating activities  (17,538)  (11,888)
         
Cash flows from investing activities        
 Business acquisitions, escrow received     478 
 Business acquisitions, net of cash acquired     (2,904)
 Purchase of marketable securities     (3,819)
 Proceeds from sales of marketable securities     3,817 
 Proceeds from maturities of marketable securities  3,374   4,168 
 Proceeds from dispositions of property and other assets, net  229   46 
     
   For the years ended 
   December 31, 2024   December 31, 2023 
 Capital expenditures  (906)  (2,084)
 Net cash provided by (used in) investing activities - continuing operations  2,697   (298)
 Net cash used in investing activities - discontinued operations  (275)  (1,071)
 Net cash provided by (used in) investing activities  2,422   (1,369)
         
Cash flows from financing activities        
Proceeds from issuance of common stock from public offering, net  7,594    
Proceeds from issuance of note payable  9,862   7,600 
Proceeds from exercise of warrants     1,200 
Repayment of common stock for payment of statutory taxes on cashless exercise of stock options     (5,379)
Repayment of note payable  (4,249)   
Repurchases of common shares     (588)
 Net cash provided by financing activities - continuing operations  13,207   2,833 
 Net cash (used in) provided by financing activities - discontinued operations  978   2,924 
 Net cash provided by financing activities  14,185   5,757 
         
 Decrease in cash, cash equivalents and restricted cash  (931)  (7,500)
 Cash and cash equivalents at the beginning of the year  1,609   9,109 
 Cash and cash equivalents at the end of the year $678  $1,609 
         
Supplemental disclosures:        
Cash paid for income taxes $1,126  $3,000 
Interest payment on the promissory notes $3,105  $932 
         
Supplemental disclosure of non-cash investing and financing activities:        
 Assets obtained in exchange for new finance lease obligations $3,783  $5,809 
 Issuance of treasury shares as collateral for a loan $3  $ 
 Stock-based compensation included in the prepaid expense $  $1,024 
 Issuance of common shares for debt conversion $  $2,400 
 Net unrealized loss, investments in marketable securities $265  $1,520 
 Issuance of warrants with unsecured promissory note $  $398 
 Common stock issued in asset acquisition $  $1,000 


Non-GAAP Financial Measure and Reconciliation

In an effort to provide investors with additional information regarding our results of operations as determined by accounting principles generally accepted in the United States of America (“GAAP”), we disclose certain non-GAAP financial measures. The primary non-GAAP financial measures we disclose are EBITDA and Adjusted EBITDA.

We define EBITDA as net income (loss) before net interest expense, income taxes, depreciation and amortization from continuing operations. Adjusted EBITDA further adjusts EBITDA by excluding acquisition costs, other non-cash items, and other unusual or non-recurring charges (as described in the table below).

Non-GAAP financial measures should not be considered as a substitute for, or superior to, measures of financial performance prepared in accordance with GAAP. These non-GAAP financial measures do not reflect a comprehensive system of accounting, differ from GAAP measures with the same names and may differ from non-GAAP financial measures with the same or similar names that are used by other companies. We compute non-GAAP financial measures using the same consistent method from quarter to quarter and year to year. We may consider whether other significant items that arise in the future should be excluded from the non-GAAP financial measures.

We use EBITDA and Adjusted EBITDA internally to evaluate and manage the Company’s operations because we believe they provide useful supplemental information regarding the Company’s ongoing economic performance. We believe that these non-GAAP financial measures provide meaningful supplemental information regarding our operating results primarily because they exclude amounts that are not considered part of ongoing operating results when planning and forecasting and when assessing the performance of the organization. In addition, we believe that non-GAAP financial information is used by analysts and others in the investment community to analyze our historical results and in providing estimates of future performance and that failure to report these non-GAAP measures could result in confusion among analysts and others and create a misplaced perception that our results have underperformed or exceeded expectations.

The following table sets forth the reconciliations of EBITDA and Adjusted EBITDA from continuing operations excluding other costs to the most comparable GAAP financial measures (in thousands):

  For the years ended 
  December 31, 2024  December 31, 2023 
GAAP loss from continuing operations (1) $(49,525) $(16,380)
Interest, net  3,350   1,188 
Income tax expense  7,195   (6,018)
Depreciation and amortization  6,187   6,050 
EBITDA  (32,793)  (15,160)
Share-based compensation expense  3,638   3,536 
Non-cash rent expense (2)  240   117 
Credit loss expense  11,018   91 
Adjusted EBITDA from continuing operations $(17,897) $(11,416)


(1) We believe that net loss from continuing operations is the financial measure calculated and presented in accordance with GAAP that is most directly comparable to EBITDA and Adjusted EBITDA. EBITDA and Adjusted EBITDA measure the Company’s operating performance without regard to certain expenses. EBITDA and Adjusted EBITDA are not presentations made in accordance with GAAP and the Company’s computation of EBITDA and Adjusted EBITDA may vary from others in the industry. EBITDA and Adjusted EBITDA have important limitations as analytical tools and should not be considered in isolation or as substitutes for analysis of the Company’s results as reported under GAAP.

(2) The non-cash portion of rent, which reflects the extent to which our GAAP rent expense recognized exceeds (or is less than) our cash rent payments. For newer leases, our rent expense recognized typically exceeds our cash rent payments, while for more mature leases, rent expense recognized is typically less than our cash rent payments.


FAQ

What was ProPhase Labs (PRPH) revenue and loss for FY2024?

PRPH reported net revenue of $6.8 million and a net loss of $53.4 million ($2.61 per share) for FY2024.

How much did ProPhase Labs sell its Pharmaloz manufacturing division for in 2025?

ProPhase Labs sold its Pharmaloz manufacturing operations for $23 million in January 2025.

What is the market potential for ProPhase's BE-Smart Esophageal Cancer test?

BE-Smart targets approximately 7 million annual endoscopies in the U.S., representing a $7-14 billion annual market opportunity.

How many genomes are in ProPhase Labs' Nebula Genomics database as of 2024?

ProPhase's Nebula Genomics controls a database of over 65,000 genomes across 130 countries.

What is the potential value of ProPhase's agreement with Crown Medical Collections?

Crown estimates recovery of approximately $50 million in insurance payments, net of contingency fees, on behalf of ProPhase.
Prophase Labs Inc

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Diagnostics & Research
Pharmaceutical Preparations
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