Praxis Precision Medicines Showcases Largest Targeted Epilepsy Portfolio in Industry at 2022 Epilepsy Day
Praxis Precision Medicines hosted its 2022 Epilepsy Day in New York City, showcasing its advancements in treating CNS disorders. CEO Marcio Souza highlighted their innovative approaches and significant progress across three major epilepsy programs: PRAX-222, PRAX-562, and PRAX-628, all expected to reach clinical stages by the end of 2022. The company aims to address unmet needs in epilepsy management with targeted therapies. This event emphasized Praxis' multi-billion-dollar market opportunity in the epilepsy sector, reflecting its commitment to rapid drug development driven by genetic insights.
- Three advanced epilepsy programs (PRAX-222, PRAX-562, PRAX-628) anticipated to enter clinical stages by year-end 2022.
- Submission of IND for PRAX-222 to the FDA for SCN2A patient trials.
- Positive preliminary Phase 1 data for PRAX-562 showcasing an unprecedented therapeutic window.
- Plans to introduce antisense oligonucleotide candidates in 2023, expanding the epilepsy pipeline.
- None.
Live event in New York City and webcast to start at 8:30 a.m. ET
BOSTON, April 27, 2022 (GLOBE NEWSWIRE) -- Praxis Precision Medicines, Inc. (NASDAQ: PRAX), a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for central nervous system (CNS) disorders characterized by neuronal excitation-inhibition imbalance, today will host its 2022 Epilepsy Day live in New York City and via webcast from 8:30 to 11:30 a.m. ET.
“We are excited to share a deeper dive into the significant work we have been doing in our epilepsy franchise, in particular our genetically-driven approach to identifying targets and how we are leveraging innovative techniques in drug development to bring a new wave of much-needed targeted therapies to patients,” said Marcio Souza, president and chief executive officer of Praxis. “We have made considerable progress enabling a high-value portfolio across each of our three franchises, and we look forward to sharing our continued progress across the entire Praxis pipeline.”
Key highlights of the event include:
- An overview of Praxis’ proprietary innovation strategy, driven by its understanding of genetics and translational tools, to rapidly discover and develop targeted CNS drugs, which has led to an epilepsy portfolio representing a multi-billion-dollar market opportunity
- Updates from Praxis’ three most advanced epilepsy programs, each of which is expected to be clinical stage by year-end 2022:
- PRAX-222: Investigational New Drug (IND) submitted to the U.S. Food and Drug Administration (FDA) proposing a seamless study design for SCN2A patients with early-onset seizures
- PRAX-562: Preliminary 28-day exposure Phase 1 data supports long-term dosing with an unprecedented therapeutic window for sodium channel blockers. A Phase 2 clinical study in cohorts of children with SCN2A epilepsy, SCN8A epilepsy, and Tuberous Sclerosis Complex (TSC) is expected to initiate in 2H2022
- PRAX-628: Expected initiation of a Phase 1 study in the fourth quarter of 2022 and a Phase 2 study in focal epilepsy in 2023
- A review of the significant progress in Praxis’ early-stage epilepsy pipeline, including plans to declare antisense oligonucleotide (ASO) candidates for PRAX-080 for PCDH19 and PRAX-090 for SYNGAP1 in 2023
- A discussion by world-renowned epilepsy experts of the unmet need in clinical management of epilepsy today and perspective on the opportunity for precision-based therapies
A live webcast and slide presentation will be available through the Events & Presentations page of the Investors + Media section of the company’s website at www.praxismedicines.com. A replay of the webcast will be available on Praxis’ website for 90 days following the event.
About Praxis
Praxis Precision Medicines is a clinical-stage biopharmaceutical company translating genetic insights into the development of therapies for CNS disorders characterized by neuronal excitation-inhibition imbalance. Praxis is applying insights from genetic epilepsies to both rare and more prevalent neurological and psychiatric disorders, using our understanding of shared biological targets and circuits in the brain. Praxis has established a broad portfolio with multiple programs, including product candidates across psychiatric disorders, movement disorders, epilepsy and other exploratory CNS indications, with three clinical-stage product candidates. For more information, please visit www.praxismedicines.com and follow us on LinkedIn and Twitter.
Forward-Looking Statements
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FAQ
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