Welcome to our dedicated page for Phio Pharmaceuticals news (Ticker: PHIO), a resource for investors and traders seeking the latest updates and insights on Phio Pharmaceuticals stock.
Phio Pharmaceuticals Corp. (Nasdaq: PHIO), headquartered in Marlborough, Massachusetts, is a clinical-stage biotechnology company focused on developing innovative immuno-oncology therapeutics. The company's proprietary INTASYL™ siRNA gene silencing technology is at the forefront of its efforts to enhance the effectiveness of immune cells in targeting and destroying tumor cells.
Phio's core product pipeline includes:
- PH-762: Targets the checkpoint protein PD-1 on immune cells, enhancing their ability to attack tumors. Currently in Phase 1b clinical trials, PH-762 is being tested for its efficacy in treating cutaneous squamous cell carcinoma, melanoma, and Merkel cell carcinoma.
- PH-804: Focuses on the suppressive immune receptor TIGIT, present on T cells and natural killer cells, to bolster immune responses against cancer.
- PH-790: Aims to silence the PD-L1 protein, which normally prevents immune cells from attacking non-harmful cells, thereby boosting the body's natural defenses against cancer.
Phio Pharmaceuticals collaborates with leading institutions such as Gustave Roussy, Medigene AG, and Helmholtz Zentrum München to advance their research and development efforts. The company's financial health, as of the latest reports, shows a cash position of $6.5 million, with a significant reduction in research and development expenses aimed at transitioning from discovery to product development.
Phio's latest updates include the presentation of new data on PH-762 at various scientific conferences and the initiation of new partnerships. These efforts underscore Phio's commitment to delivering cutting-edge cancer treatments and improving patient outcomes.
For more details, visit the company's website at www.phiopharma.com.
Phio Pharmaceuticals (NASDAQ: PHIO) announced its upcoming presentation at the American Society of Gene & Cell Therapy's 2024 Advancing Gene + Cell Therapies for Cancer conference. The event will be held virtually and in Philadelphia on October 16-17, 2024.
The presentation will focus on Phio's INTASYL compound PH-894, which targets BRD4 to enhance Natural Killer (NK) cell-based immunotherapy. Specifically, PH-894 silences BRD4 and enhances activation and proliferation of NK cells for Adoptive Cell Therapy (ACT).
Presentation details:
- Title: INTASYL PH-894: Targeting BRD4 to Enhance NK Cell-Based Immunotherapy
- Presenter: Melissa Maxwell
- Date: October 16, 2024
- Time: 8 a.m. - 6:45 p.m. ET
- Location: FDR Ballroom, Wyndham Hotel, Philadelphia Historic District
Phio Pharmaceuticals Corp. (NASDAQ: PHIO) announced it will present data on its INTASYL technology platform at the 20th Annual Oligonucleotide Therapeutics Society (OTS) Meeting in Montreal from October 6th-9th. The presentation, titled 'INTASYL Self-Delivering RNAi: a Flexible Platform for Cancer Treatment', will focus on how INTASYL can enhance ex vivo expansion processes to improve functionality and outcomes of adoptive cell therapies like NK, TIL, or CAR-T.
INTASYL's advantage lies in its simplified chemical composition, designed to reduce toxicity and improve tolerability and efficacy in therapeutic development. The poster presentation (Number P180) will be given by Melissa Maxwell on October 8th from 3:45-6:45 PM at the Centre Mont-Royal in Montreal.
Phio Pharmaceuticals (NASDAQ: PHIO), a clinical stage biotechnology company, has announced its participation in the Renmark Financial Communications Virtual Non-Deal Roadshow Series. The event is scheduled for Tuesday, September 24, 2024, at 12 PM EDT.
Mr. Robert Bitterman, CEO and Chairman of the Board, will present on behalf of Phio Pharmaceuticals. The company specializes in INTASYL® siRNA gene silencing technology, designed to enhance immune cells' effectiveness in killing tumor cells.
Stakeholders, investors, and interested individuals are invited to register and attend this live event. A replay will be available on the Renmark Financial Communications Inc. website. Attendees are advised to use the latest version of Google Chrome for optimal connectivity.
Phio Pharmaceuticals (NASDAQ: PHIO) announced a presentation at the 9th Annual CAR-TCR Summit in Boston, MA, showcasing its INTASYL self-delivering RNAi technology. The presentation, titled 'INTASYL Self-Delivering RNAi: A Flexible Platform to Improve Adoptive Cell Therapy,' will be given by Melissa Maxwell on September 17th. INTASYL is designed to enhance cell potency and yield in Adoptive Cell Therapy, potentially offering a more effective approach for cancer treatment. The technology aims to make immune cells more effective in killing tumor cells through gene silencing. This presentation highlights Phio's efforts to advance its innovative platform in the competitive field of cell therapy.
Phio Pharmaceuticals (NASDAQ: PHIO), a clinical stage biotech company, will participate in the H.C. Wainwright 26th Annual Global Investment Conference from September 9-11, 2024, in New York City. CEO Robert Bitterman will present on the company's INTASYL siRNA gene silencing technology, which aims to enhance immune cells' ability to kill tumor cells.
The presentation will cover:
- INTASYL technology overview
- Associated patents and intellectual property
- Ongoing Phase 1b clinical trial of PH-762, Phio's lead INTASYL compound
Phio's presentation will be streamed online starting September 9th at 7:00 AM ET. The management team will also be available for one-on-one meetings during the conference.
Phio Pharmaceuticals (NASDAQ: PHIO), a clinical stage biotech company specializing in INTASYL® siRNA gene silencing technology, has announced its participation in the Renmark Financial Communications Virtual Non-Deal Roadshow Series. The event is scheduled for Thursday, September 5, 2024, at 12 PM EDT.
Robert Bitterman, CEO and Chairman of the Board, will present on behalf of Phio Pharmaceuticals. The presentation will include a live Q&A session. Stakeholders, investors, and interested individuals are invited to register and attend this live event. A replay will be available on the Renmark Financial Communications website.
Phio's INTASYL® technology is designed to enhance the effectiveness of immune cells in killing tumor cells, positioning the company at the forefront of innovative cancer treatments.
Phio Pharmaceuticals Corp. (NASDAQ: PHIO) reported its Q2 2024 financial results and provided a business update. Key highlights include:
1. Positive safety recommendation for PH-762 Phase 1b trial, with no dose-limiting toxicities.
2. Addition of a fifth clinical trial site for the PH-762 study.
3. New patent granted in South Korea for INTASYL compounds targeting aging skin disorders.
4. Warrant exercise agreements resulting in $3.1 million gross proceeds.
5. Completion of a 1-for-9 reverse stock split.
6. Regained compliance with Nasdaq's minimum bid price requirement.
7. Appointment of Robert M. Infarinato as CFO.
8. Exploratory collaboration with a global skin care company.
Financial results show cash position of $4.7 million as of June 30, 2024, with decreased R&D and G&A expenses compared to Q2 2023.
Phio Pharmaceuticals Corp. (NASDAQ: PHIO) has announced an exploratory collaboration with a leading luxury skin care company to explore opportunities for its patented INTASYL compound in cosmeceutical applications. This collaboration aims to leverage Phio's gene silencing technology for aging skin disorders. CEO Robert Bitterman highlighted the significance of this step in demonstrating INTASYL's versatility across multiple applications.
Phio's INTASYL patent portfolio now includes 77 issued patents covering the silencing of over 25 gene targets in various fields, including dermatology, immuno-oncology, ophthalmology, and viral disorders. The technology is designed to enhance the effectiveness of immune cells in killing tumor cells, with applications for both intratumoral treatment and adoptive cell therapy.
Phio Pharmaceuticals Corp. (NASDAQ: PHIO), a clinical stage biotechnology company specializing in INTASYL™ siRNA gene silencing technology, has announced the appointment of Robert M. Infarinato as their new Vice President and Chief Financial Officer, effective August 1, 2024. Infarinato brings over 20 years of financial and accounting leadership experience to the role, where he will serve as Principal Financial Officer overseeing accounting, finance, treasury, investor relations, and administration.
Infarinato's extensive background includes leadership positions in healthcare and pharmaceuticals, such as roles at Abington Health, Rhone Poulenc Rorer, and Pfizer. CEO Robert Bitterman expressed enthusiasm about Infarinato joining the executive team, highlighting his broad experience across multiple financial functions within the healthcare sector.
Phio Pharmaceuticals announced the exercise of certain outstanding warrants, securing approximately $3.1 million in gross proceeds. These warrants, originally priced between $324.00 and $9.72 per share, were exercised at a reduced price of $5.45 per share.
The exercise includes the issuance of new unregistered warrants for additional shares, exercisable at $5.45 per share, with varying terms of five and one-half years and eighteen months. H.C. Wainwright & Co. acted as the exclusive placement agent, and the company plans to use the net proceeds for working capital and general corporate purposes.
The offering, expected to close around July 12, 2024, is contingent on customary closing conditions. The new warrants were issued under an exemption from the registration requirements of the 1933 Act and are available only to accredited investors.
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