Psyence Biomedical Welcomes Results of a Recent Study Highlighting Benefits of Nature Derived Psilocybin Vs. Synthetic Psilocybin
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The findings from the Hebrew University study on nature-derived psilocybin present a significant advancement in the field of psychedelic medicine. The potential of a more potent effect on neuroplasticity could be a game-changer for treatments involving mental health, particularly in the palliative care sector. The concept of neuroplasticity is central to understanding how the brain adapts and heals and a substance that can enhance this process might offer substantial benefits for patients with life-limiting diagnoses.
Furthermore, the mention of 'the entourage effect' suggests that a combination of molecules found in natural psilocybin could lead to better therapeutic outcomes. This is analogous to findings in cannabinoid research, where the combination of various compounds in the cannabis plant is believed to provide superior effects compared to isolated compounds. If similar principles apply to psilocybin, Psyence Biomed's focus on a nature-derived product could differentiate their treatment options and potentially lead to a more effective therapy.
The projected growth of the U.S. Palliative Care market to $28.6 billion by 2030 indicates a substantial economic opportunity for companies like Psyence Biomed. The economic implications of introducing an effective, nature-derived psilocybin therapy could be profound, not only in terms of market share but also in the potential to reduce healthcare costs. The report from the Journal of Clinical Oncology underscores the cost-saving benefits of palliative care, showing an 18.7% decrease in hospitalizations.
Considering the cost implications of Adjustment Disorder in the context of life-limiting illnesses, an effective treatment could alleviate the financial burden on the healthcare system. The potential to improve patient quality of life while simultaneously reducing healthcare costs makes this development of interest to stakeholders across the healthcare value chain, from patients and providers to payers and investors.
Adjustment Disorder is a prevalent and distressing condition for patients facing life-limiting diagnoses, such as cancer. The integration of psilocybin-assisted psychotherapy in palliative care could represent a substantial improvement in the management of psychological distress in these patients. The therapeutic model of combining psychedelics with psychotherapy is gaining traction and evidence suggesting that nature-derived psilocybin could offer enhanced benefits adds to the potential of this treatment approach.
Psyence Biomed's upcoming Phase llb clinical trial will be closely watched by the oncology community for its implications on patient care. If successful, this could lead to a paradigm shift in how emotional and psychological support is provided to patients with life-limiting conditions, potentially setting a new standard in palliative care practices.
The study, published in the journal Molecular Psychiatry, suggests that nature-derived psilocybin may be demonstrably more therapeutic than its synthetic analog
Benefits are thought to include a more potent and prolonged effect on neuroplasticity
NEW YORK, March 18, 2024 (GLOBE NEWSWIRE) -- Psyence Biomedical Ltd. (Nasdaq:PBM) ("Psyence Biomed" or the "Company") today issued a statement welcoming the results of a recent study finding evidence that nature-derived psilocybin may be demonstrably more therapeutic than synthetic psilocybin.
Published on February 20, 2024, in the journal Molecular Psychiatry, the study was conducted by a research team from Hebrew University, and supervised by Professor Bernard Lerer, MD, Executive Director of the Hadassah Brain Labs and Center for Psychedelic Research. The study presents evidence that nature (mushroom)-derived psilocybin delivers a “more potent and prolonged effect” on “neuroplasticity” than its synthetic analog. “Neuroplasticity” is increasingly recognized as the gold standard by which the therapeutic efficacy of psychedelic pharmaceutical medicines can be measured. The study in mice also suggests that a potential combination of molecules that the study refers to as “the entourage effect” may provide “enhanced or prolonged therapeutic effects” not found in synthetic psilocybin.
Dr. Neil Maresky, MD, Chief Executive Officer of Psyence Biomed, the first Nasdaq-traded botanical (non-synthetic) psilocybin biopharma company, stated, “This evidence-based and independent finding affirms Psyence Biomed’s pioneering commitment to nature-derived psilocybin and developing an FDA-approved, nature-derived psilocybin therapeutic for Palliative Care.”
Palliative Care is a holistic and integrative medical specialty that provides patients who have received a life-limiting diagnosis with treatment for their emotional, physical, or spiritual distress or discomfort. Proprietary research suggests that the U.S. Palliative Care market is projected to grow to
While most psychedelic companies research synthetic psilocybin, Psyence Biomed stands alone as the only Nasdaq traded biopharmaceutical company to research a nature-derived psilocybin candidate to treat Adjustment Disorder in the context of Palliative Care. Psyence Biomed has recently received ethics approval for the trial protocol for its Phase llb clinical trial to move forward. It is expected that the first patients will be randomized in the second quarter of 2024, with topline results available in 2025.
The Psyence Biomed study will examine the use of nature-derived psilocybin as a treatment for Adjustment Disorder due to a recent cancer diagnosis in the Palliative Care context. Adjustment Disorder is a serious condition affecting approximately
Dr. Maresky added, “Developing therapies such as psilocybin-assisted psychotherapy, which may reduce patients’ stress and anxiety and result in better quality of life as they navigate a cancer diagnosis, can be very impactful. With psilocybin-assisted psychotherapy, there is an opportunity to both improve patient quality of life while also reducing health care costs associated with Palliative Care.”
Palliative Care is also increasingly recognized by the oncology community as a solution to stretching scarce health care resources. According to a separate report this month in the Journal of Clinical Oncology, the ASCO journal, “Randomized controlled trials have demonstrated that Palliative Care can improve quality of life and survival for outpatients with advanced cancer.” The JCO study found that with Palliative Care, hospitalizations decreased
Neither Psyence Biomedical nor any of its investors or affiliates funded or in any way sponsored the Hebrew University study. The full text of the paper can be found here: https://link.springer.com/content/pdf/10.1038/s41380-024-02477-w.pdf
The JCO paper can be found here: https://ascopubs.org/doi/10.1200/OP.23.00576
About Psyence Biomed:
Psyence Biomedical Ltd. is a life science biotechnology company listed on Nasdaq (Nasdaq:PBM), with a focus on natural psychedelics. The Company is developing nature-derived psilocybin mushroom products for the healing of psychological trauma and its mental health consequences in the context of palliative care. Our name “Psyence” combines the words psychedelic and science to affirm our commitment to producing psychedelic medicines developed through evidence-based research. We work to develop advanced natural psilocybin products for clinical research and development.
Learn more at www.psyencebiomed.com and on LinkedIn.
Contact Information
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General Information: info@psyencebiomed.com
Phone: +1 416-477-1708
Investor Contact:
Jeremy Feffer
Managing Director
LifeSci Advisors
jfeffer@lifesciadvisors.com
Forward Looking Statements
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The Company makes no medical, treatment or health benefit claims about the Company’s proposed products. The U.S. Food and Drug Administration, Health Canada or other similar regulatory authorities have not evaluated claims regarding psilocybin, psilocybin analogues, or other psychedelic compounds or nutraceutical products. The efficacy of such products has not been confirmed by approved research. There is no assurance that the use of psilocybin, psilocybin analogues, or other psychedelic compounds or nutraceuticals can diagnose, treat, cure or prevent any disease or condition. Vigorous scientific research and clinical trials are needed. The Company has not conducted clinical trials for the use of its proposed products. Any references to quality, consistency, efficacy, and safety of potential products do not imply that the Company verified such in clinical trials or that the Company will complete such trials. If the Company cannot obtain the approvals or research necessary to commercialize its business, it may have a material adverse effect on the Company’s performance and operations.
FAQ
What study suggests nature-derived psilocybin may be more therapeutic than synthetic?
Who supervised the research team conducting the study on nature-derived psilocybin?
What is the potential combination of molecules mentioned in the study?
What is the projected growth of the U.S. Palliative Care market in 2030?
What is Adjustment Disorder, and how many patients does it affect?
What is the expected timeline for Psyence Biomed's Phase llb clinical trial on nature-derived psilocybin?
