Welcome to our dedicated page for Panbela Therapeutics news (Ticker: PBLA), a resource for investors and traders seeking the latest updates and insights on Panbela Therapeutics stock.
Panbela Therapeutics Inc. (PBLA) is a clinical-stage biopharmaceutical company pioneering therapies targeting polyamine metabolism in aggressive cancers. This page serves as the definitive source for verified news and press releases related to clinical trials, research breakthroughs, and corporate developments.
Investors and researchers will find timely updates on PBLA's oncology pipeline, including ivospemin (SBP-101) and combination therapies under investigation. Our curated collection provides essential context for understanding the company's progress in pancreatic, ovarian, and other solid tumor research.
Key content categories include clinical trial milestones, regulatory updates, peer-reviewed data publications, and strategic partnership announcements. All materials are sourced directly from the company and reputable medical journals to ensure accuracy.
Bookmark this page for streamlined access to PBLA's latest developments in cancer therapeutics. For comprehensive analysis of how these updates may impact therapeutic landscapes and investment considerations, consult your financial advisor or medical professional.
Panbela Therapeutics, Inc. (Nasdaq: PBLA) announced a business update and financial results for Q2 2021, marked by significant clinical advancements. Highlights include the issuance of a patent for a novel production method for SBP-101, a $10 million common stock offering, and inclusion in the Russell Microcap Index. The company reported a net loss of $2.2 million, or $0.22 per share, with total cash at $6.4 million. SBP-101 showed a 48% objective response rate in clinical trials, supporting its further development in pancreatic cancer. Upcoming milestones include new trials by year-end.
Panbela Therapeutics (Nasdaq: PBLA) announced the issuance of U.S. patent US 11,098,005 for a novel method to produce its lead product, SBP-101, developed with Syngene International Ltd. This patent reduces the production steps from seventeen to six and extends patent protection to 2039. The CEO highlighted benefits including shorter manufacturing times and cost efficiency, which could enhance commercialization efforts. SBP-101 targets pancreatic cancer and has shown potential in clinical studies without exacerbating common chemotherapy-related side effects.
Panbela Therapeutics (Nasdaq: PBLA) announced a conference call for August 11, 2021, at 4:30 PM ET to discuss its second quarter results ending June 30, 2021. The call will be accessible via telephone and online. The company is developing its proprietary drug, SBP-101, for treating metastatic pancreatic ductal adenocarcinoma, showing promise in clinical studies. Importantly, SBP-101 has demonstrated potential efficacy without exacerbating common chemotherapy side effects, supporting additional evaluation in clinical trials.
Panbela Therapeutics (Nasdaq: PBLA) announced its participation in the Access to Giving Virtual Conference on July 15, 2021, at 10:30 a.m. ET. The presentation will be delivered by Jennifer K. Simpson, the company's President & CEO. The conference enables companies of varying market capitalizations to engage with investors for charity. Panbela's investigational therapy, SBP-101, aims to treat metastatic pancreatic cancer, showing promise in inhibiting tumor growth without severe side effects traditionally associated with chemotherapy. For registration, visit the event's website.
Panbela Therapeutics, Inc. (Nasdaq: PBLA) has successfully closed a public offering of 3,333,334 shares at $3.00 per share, raising approximately $10 million. The funds will be directed towards the ongoing clinical development of SBP-101, aimed at treating metastatic pancreatic cancer, and for general corporate purposes. This offering was managed by H.C. Wainwright & Co. and conducted under an effective shelf registration statement with the SEC.
Panbela Therapeutics (Nasdaq: PBLA) announced an expanded public offering of 3,333,334 shares at $3.00 per share, raising approximately $10 million. The offering is set to close around July 2, 2021, pending customary conditions. H.C. Wainwright & Co. serves as the sole book-running manager. There is a 30-day option for the underwriter to buy an additional 500,000 shares. Proceeds will fund the clinical development of SBP-101, intended for treating pancreatic cancer, and for general corporate purposes. Shares are offered under an effective SEC registration statement.
Panbela Therapeutics (Nasdaq: PBLA) announced an underwriting agreement with H.C. Wainwright & Co. for the purchase of 1,666,667 shares of common stock at $3.00 each. The public offering, estimated to close around July 2, 2021, is expected to generate approximately $5.0 million in gross proceeds. Proceeds will be utilized for the clinical development of SBP-101 and general corporate needs. The underwriter holds a 30-day option to acquire an additional 250,000 shares. This offering is registered under the effective Form S-3 registration statement.
Panbela Therapeutics, Inc. (Nasdaq: PBLA) will join the Russell Microcap® Index effective June 28, 2021. This inclusion, confirmed by FTSE Russell, grants the company access to a broader investor base and establishes it in appropriate growth and value style indexes. CEO Jennifer K. Simpson expressed optimism about communicating the company's strategies to a larger audience. The membership is crucial as Russell indexes are benchmarks for over $10.6 trillion in assets. The company is focused on SBP-101, a promising treatment for pancreatic cancer, showing potential benefits without exacerbating typical chemotherapy side effects.
Minneapolis, June 4, 2021 - Panbela Therapeutics (Nasdaq: PBLA) announced interim data from its Phase 1b study of SBP-101, a polyamine analogue, combined with gemcitabine and nab-paclitaxel for metastatic Pancreatic Ductal Adenocarcinoma (PDA). The data suggest a potential enhancement in treatment efficacy, particularly with an objective response rate of 71% in cohort 2. However, cohort 4 faced treatment interruptions. The company plans to initiate a randomized Phase 2 study soon and will exclude patients with retinal toxicity history in future trials.
Panbela Therapeutics, Inc. (Nasdaq: PBLA) announced the retirement of founder Michael T. Cullen, MD, MBA, effective May 25, 2021. Although he steps down as an employee, he will remain as Chair of the Board of Directors. Dr. Cullen's tenure spanned over a decade, where he played a pivotal role in advancing SBP-101 for metastatic pancreatic cancer. CEO Jennifer K. Simpson highlighted Cullen's contributions and expressed enthusiasm for his ongoing guidance in the company's next phase. SBP-101 shows potential for tumor growth inhibition and is being investigated further in clinical trials.
