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Palisade Bio Inc - PALI STOCK NEWS

Welcome to our dedicated page for Palisade Bio news (Ticker: PALI), a resource for investors and traders seeking the latest updates and insights on Palisade Bio stock.

Palisade Bio Inc. (NASDAQ: PALI) is a clinical-stage biopharmaceutical company dedicated to advancing the science of intestinal health through the development of innovative therapeutics. The company focuses on addressing critical unmet medical needs by protecting and enhancing the integrity of the intestinal barrier, a vital component of gastrointestinal health. Operating within the dynamic biotechnology and pharmaceutical industry, Palisade Bio is carving out a niche in the treatment of gastrointestinal disorders, particularly inflammatory bowel disease (IBD), which includes conditions such as ulcerative colitis (UC) and Crohn's disease (CD).

Core Business and Therapeutic Focus

At the heart of Palisade Bio’s mission is its commitment to improving patient outcomes through groundbreaking research and development (R&D). The company’s primary focus is its proprietary pipeline of therapeutics designed to address the root causes of intestinal barrier dysfunction. By targeting the mechanisms that compromise intestinal health, Palisade Bio aims to offer novel solutions that go beyond symptom management to deliver long-term benefits for patients.

Palisade Bio’s portfolio includes its lead candidate, PALI-2108, which is being developed for the treatment of IBD, with a particular focus on UC and CD. Additionally, the company is conducting research on PALI-1908, further demonstrating its commitment to innovation in gastrointestinal therapeutics. These investigational treatments are designed to address the critical need for effective, targeted therapies that improve intestinal barrier function, a key factor in the progression of many gastrointestinal disorders.

Industry Context and Competitive Landscape

Palisade Bio operates in a highly specialized segment of the biopharmaceutical industry, where the development of gastrointestinal therapies represents a significant growth opportunity. The company’s focus on intestinal barrier integrity sets it apart from competitors that often emphasize broader gastrointestinal treatments. By addressing the underlying causes of intestinal dysfunction, Palisade Bio aims to differentiate itself in a crowded and competitive market.

The pharmaceutical industry is characterized by rigorous regulatory standards, high R&D costs, and lengthy clinical trial processes. As a clinical-stage company, Palisade Bio faces these challenges while striving to demonstrate the safety and efficacy of its therapies. Success in this space requires not only scientific innovation but also strategic partnerships, effective clinical trial management, and eventual regulatory approval.

Business Model and Revenue Streams

As a clinical-stage company, Palisade Bio does not yet generate revenue from product sales. Instead, its business model relies on securing funding through equity financing, strategic partnerships, and potential licensing agreements. The company’s ability to attract investment is closely tied to the progress of its clinical trials and the promise of its therapeutic candidates. By focusing on a niche area with significant unmet medical needs, Palisade Bio aims to position itself as a valuable partner for larger pharmaceutical companies and healthcare organizations.

Significance and Potential Impact

Palisade Bio’s work has the potential to transform the treatment landscape for patients suffering from debilitating gastrointestinal disorders. By prioritizing the integrity of the intestinal barrier, the company addresses a critical aspect of gastrointestinal health that has been largely overlooked by traditional therapies. This focus not only enhances its scientific credibility but also underscores its commitment to delivering meaningful solutions for patients.

In summary, Palisade Bio Inc. represents a promising player in the biopharmaceutical industry, leveraging cutting-edge science to tackle complex gastrointestinal disorders. While the company is still in the clinical development phase, its innovative approach to intestinal health positions it as a potential leader in this specialized field. Through its dedication to research, patient-centered focus, and strategic positioning, Palisade Bio continues to advance its mission of improving lives through better gastrointestinal health.

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Palisade Bio, Inc. (PALI) to present at the Virtual Investor Lunch Break event, featuring an overview by CEO J.D. Finley and CMO Dr. Mitch Jones. The live webcast on April 16, 2024, will focus on the company's business outlook and opportunities in autoimmune, inflammatory, and fibrotic diseases.
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Palisade Bio, Inc. (Nasdaq: PALI) announces the advancement of PALI-2108, a treatment for moderate-to-severe ulcerative colitis, towards Phase 1 clinical study by the end of the year. The company presented at IBD Innovate, discussing the development, differentiation, and clinical pathway of PALI-2108.
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Palisade Bio, Inc. (Nasdaq: PALI) announces a 1-for-15 reverse stock split to increase per share trading price and comply with Nasdaq listing requirements. The split will be effective on April 5, 2024, with trading under the symbol 'PALI' and new CUSIP number 696389402.
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Palisade Bio, Inc. (PALI) progresses PALI-2108 towards Phase 1 clinical study for ulcerative colitis treatment, forms Clinical Advisory Board, and reports financial results for 2023. The company has sufficient cash to achieve milestones into 2025.
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Palisade Bio, Inc. (PALI) announces acceptance of abstract for poster presentation at DDW 2024 for their novel therapeutic PALI-2108 for ulcerative colitis treatment.
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Palisade Bio, Inc. announces a strategic streamlining of the Board to align with current clinical development and corporate vision. The company is advancing PALI-2108 for the treatment of moderate-to-severe ulcerative colitis towards a Phase 1 clinical study, with significant progress in various areas.
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Palisade Bio, Inc. issued a correction to its press release, clarifying the timeline for the PALI-2108 Phase 1 clinical study. The original release incorrectly stated that the study was on track to commence next year, while the company reiterates that it is set to launch in 2024.
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Palisade Bio, Inc. (Nasdaq: PALI) has appointed two renowned gastroenterologists, Dr. Bruce Sands and Dr. Florian Rieder, to its Clinical Advisory Board (CAB) to advise on the development of novel therapeutics for serious chronic gastrointestinal diseases, with a focus on Inflammatory Bowel Disease (IBD). The company's lead asset PALI-2108 for the treatment of ulcerative colitis is on track for a Phase 1 clinical study launch next year.
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Palisade Bio, Inc. announced an agreement to exercise existing warrants, resulting in gross proceeds of approximately $2.5 million prior to deducting placement agent fees and estimated offering expenses. The company will issue new unregistered warrants to purchase shares of common stock in a private placement. The net proceeds from the offering will be used for working capital and general corporate purposes.
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Palisade Bio, Inc. presented positive preclinical data of its lead asset, PALI-2108, at the Crohn’s & Colitis Congress. The preclinical data showed that PALI-2108 is safe and well-tolerated, orally delivered, and colon-activated, with low systemic exposure. The company is advancing PALI-2108 for the treatment of moderate-to-severe ulcerative colitis (UC) towards a Phase 1 clinical study expected to commence in 2024. The preclinical studies demonstrated that PALI-2108 offers localized bioactivation, colon-specific distribution, similar target engagement to other PDE4 inhibitors, dose-dependent efficacy in a mouse UC model, and no systemic toxicity in dogs, with a large therapeutic window due to local activation.
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FAQ

What is the current stock price of Palisade Bio (PALI)?

The current stock price of Palisade Bio (PALI) is $0.8276 as of March 3, 2025.

What is the market cap of Palisade Bio (PALI)?

The market cap of Palisade Bio (PALI) is approximately 2.4M.

What does Palisade Bio Inc. specialize in?

Palisade Bio specializes in developing therapeutics that protect and enhance the integrity of the intestinal barrier, focusing on gastrointestinal disorders like IBD.

What are Palisade Bio’s key therapeutic candidates?

The company’s key candidates are PALI-2108, aimed at treating IBD including ulcerative colitis and Crohn's disease, and PALI-1908, which is under research.

How does Palisade Bio differentiate itself from competitors?

Palisade Bio focuses on the intestinal barrier, addressing the root causes of gastrointestinal disorders rather than just managing symptoms.

What is Palisade Bio’s business model?

As a clinical-stage company, Palisade Bio relies on funding through equity financing, partnerships, and potential licensing agreements.

What challenges does Palisade Bio face in its industry?

The company faces challenges such as high R&D costs, lengthy clinical trials, and the need for regulatory approval in a competitive pharmaceutical landscape.

What is the significance of the intestinal barrier in gastrointestinal health?

The intestinal barrier plays a critical role in maintaining gut health; its dysfunction is linked to conditions like IBD, making it a key therapeutic target.

Who are Palisade Bio’s target customers?

The company’s target customers include healthcare providers, hospitals, and research institutions treating patients with gastrointestinal disorders.

What is the industry context for Palisade Bio’s work?

Palisade Bio operates in the biopharmaceutical industry, focusing on gastrointestinal health, a niche with significant unmet medical needs.
Palisade Bio Inc

Nasdaq:PALI

PALI Rankings

PALI Stock Data

2.42M
2.74M
1.88%
3.58%
2.82%
Biotechnology
Biological Products, (no Disgnostic Substances)
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United States
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