Welcome to our dedicated page for Oric Pharmaceuticals news (Ticker: ORIC), a resource for investors and traders seeking the latest updates and insights on Oric Pharmaceuticals stock.
Oric Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, is dedicated to discovering and developing innovative therapies for the treatment of cancer. Headquartered in South San Francisco, California, Oric Pharmaceuticals was founded in 2014 and has since focused on addressing the challenging problem of cancer resistance to existing treatments.
The company's lead product candidate is ORIC-101, a small molecule antagonist of the glucocorticoid receptor. This receptor has been identified as a key player in the resistance mechanisms against various classes of cancer therapeutics, particularly across solid tumors. By targeting this receptor, ORIC-101 aims to enhance the effectiveness of existing cancer treatments.
Another significant asset in Oric's pipeline is ORIC-533, an orally bioavailable small molecule inhibitor of CD73. CD73 plays a role in resistance to both chemotherapy and immunotherapy, and ORIC-533 is being developed to counteract this resistance, offering a potential new avenue for treating patients who do not respond to current therapies.
In addition to ORIC-101 and ORIC-533, the company is also developing ORIC-944 and ORIC-114, each targeting different mechanisms of cancer resistance. ORIC-944 has shown promise in initial Phase 1b data, and the company has outlined several anticipated milestones for these programs in the near future.
Oric Pharmaceuticals demonstrates a robust commitment to advancing the field of precision oncology. The company leverages its expertise in hormone-dependent cancers, precision oncology, and key tumor dependencies to build a diverse pipeline of therapies. These efforts are supported by strategic partnerships and collaborations aimed at accelerating the development and commercialization of their treatment candidates.
Financially, Oric Pharmaceuticals has provided guidance and updates to keep stakeholders informed about their progress and strategic direction. For the latest news and developments, investors and interested parties are encouraged to stay tuned to the company's announcements.
Contact: Dominic Piscitelli, Chief Financial Officer
ORIC Pharmaceuticals, a clinical stage oncology company, announced four preclinical poster presentations at the 2021 AACR virtual annual meeting scheduled for April 10-15, 2021. The data focuses on ORIC's lead program ORIC-101 and three other candidates: ORIC-533, ORIC-944, and ORIC-114, which aim to address cancer resistance mechanisms. Each candidate shows potential best-in-class differentiation, with ORIC-101 reversing GR-mediated resistance in prostate cancer models. These advancements underscore ORIC's commitment to improving cancer treatment outcomes.
ORIC Pharmaceuticals, focused on overcoming cancer resistance, will present a company overview at two upcoming conferences. Jacob Chacko, M.D., CEO, will deliver an on-demand presentation at the H.C. Wainwright Global Life Sciences Conference on March 9, 2021, and a live presentation at the Oppenheimer 31st Annual Healthcare Conference on March 16, 2021. Webcasts of both events will be accessible on the company’s website for 90 days. ORIC’s lead product, ORIC-101, targets glucocorticoid resistance in solid tumors and is currently in Phase 1b trials.
ORIC Pharmaceuticals, a clinical stage oncology company, announced participation in two investor conferences in February 2021. The Guggenheim Healthcare Talks 2021 Oncology Day features a virtual fireside chat on February 11 at 1:00 p.m. ET, while the LifeSci Partners Precision Oncology Day will host investor meetings on February 17. A live webcast of the fireside chat will be available on their website for 90 days post-event. ORIC focuses on developing therapies addressing cancer resistance mechanisms, with notable candidates including ORIC-101, ORIC-533, ORIC-944, and ORIC-114.
ORIC Pharmaceuticals (Nasdaq: ORIC) has outlined significant developments for 2021, focusing on clinical programs and pipeline expansion. Key highlights include the ongoing enrollment for ORIC-101 trials, with initial readouts anticipated this year. The company plans to submit three IND applications for ORIC-533, ORIC-944, and ORIC-114. Financially, ORIC reported $293.6 million in cash at the end of 2020, sufficient to fund operations into the second half of 2023. Jacob Chacko, CEO, emphasized these advancements position ORIC for a dynamic year ahead.
ORIC Pharmaceuticals, a clinical stage oncology company, will present at the 39th Annual J.P. Morgan Healthcare Conference on January 12, 2021, at 12:40 p.m. PT. CEO Jacob Chacko will provide an overview of the company, which is focused on overcoming therapeutic resistance in cancer treatments. Their lead candidate, ORIC-101, is currently in Phase 1b trials for metastatic prostate cancer and advanced solid tumors in combination with Xtandi and Abraxane, respectively. A live webcast of the presentation will be available on their website.
ORIC Pharmaceuticals announced the initiation of Part II expansion of the Phase 1b study of ORIC-101, a glucocorticoid receptor antagonist, combined with Abraxane for treating advanced solid tumors. This stage will enroll up to 132 patients with pancreatic ductal adenocarcinoma, ovarian cancer, triple-negative breast cancer, and others. The recommended Phase 2 dose was found to be 160 mg of ORIC-101 with 75 mg/m² of Abraxane. The trial aims to address significant unmet medical needs in these cancer types.
ORIC Pharmaceuticals announced the completion of its underwritten public offering of 5,796,000 shares, raising approximately $133.3 million. This includes the full exercise of the underwriters’ option to purchase an additional 756,000 shares, priced at $23.00 each. The offering was managed by J.P. Morgan, Citigroup, Jefferies, and Guggenheim. Funds will support ORIC's pipeline, including its lead candidate ORIC-101, aimed at combating cancer therapeutic resistance.
ORIC Pharmaceuticals (Nasdaq: ORIC) has announced a public offering of 5,040,000 shares of common stock, priced at $23.00 per share, aiming to raise approximately $115.9 million. The underwriters have a 30-day option to purchase an additional 756,000 shares. The offering is slated to close on November 17, 2020, pending customary conditions. J.P. Morgan, Citigroup, Jefferies, and Guggenheim are the joint book-running managers for this offering, which is intended to bolster ORIC's pipeline for cancer therapeutics, specifically targeting resistance mechanisms.
ORIC Pharmaceuticals, Inc. (Nasdaq: ORIC) has announced a public offering of 4,000,000 shares of its common stock, with plans to grant underwriters a 30-day option for an additional 600,000 shares. The offering, subject to market conditions, is underwritten by J.P. Morgan, Citigroup, Jefferies, and Guggenheim Securities. A registration statement has been filed with the SEC, but the offering is contingent upon its effectiveness. ORIC focuses on developing treatments for therapeutic resistance in cancer, including lead candidate ORIC-101 currently in Phase 1b trials.
The press release from ORIC Pharmaceuticals, a clinical stage oncology company, highlights CEO Jacob Chacko's participation in two upcoming investor conferences in November 2020. The events include a virtual fireside chat at the Jefferies Virtual London Healthcare Conference on November 18 and meetings at the SVB Leerink Oncology 1x1 Day on November 19. A live webcast of the fireside chat will be accessible on the company’s website, with a replay available for 90 days. ORIC is focused on developing therapies to combat therapeutic resistance in cancer.
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