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Organovo Holding - ONVO STOCK NEWS

Welcome to our dedicated page for Organovo Holding news (Ticker: ONVO), a resource for investors and traders seeking the latest updates and insights on Organovo Holding stock.

Overview of Organovo Holding (ONVO)

Organovo Holding (ONVO) is a clinical stage biotechnology company that excels in designing and creating functional, three-dimensional human tissues using advanced 3D tissue engineering techniques. As a pioneer in the field of drug discovery and medical research, Organovo leverages proprietary technology to fabricate human tissue models that closely mimic native tissue architecture, function, and disease pathology. This innovative approach not only enables accurate biological disease models but also supports faster, more cost-effective therapeutic development.

Core Business and Technological Innovation

At the heart of Organovo’s operations is its breakthrough technology for fabricating functional 3D human tissues. The company collaborates with pharmaceutical companies and academic institutions, employing its engineered tissues to simulate complex human diseases. This technology facilitates a new dimension of preclinical testing, allowing researchers to study disease processes in an environment that closely resembles in vivo conditions. Organovo's technology is especially significant in accelerating drug development, as realistic tissue models can reveal critical insights into drug efficacy and safety early in the research cycle.

Scientific and Clinical Research Applications

Organovo’s expertise extends into the realm of clinical research where its preclinical data supports the development of novel drug candidates. One of its notable endeavors is the investigation of FXR314, a drug candidate for inflammatory bowel disease, including ulcerative colitis. By utilizing its 3D human tissue models, the company is able to demonstrate clinical promise, further emphasizing its role in translating laboratory research into potential therapeutic applications for complex diseases. This versatile platform not only aids in understanding gastrointestinal and liver diseases but has implications in oncology and metabolic liver conditions as well.

Collaborations and Industry Recognition

The company’s approach to tissue engineering has garnered attention from diverse sectors. By establishing strategic partnerships with leading academic and pharmaceutical entities, Organovo has positioned itself as an essential collaborator in the development of robust disease models. Its scientific advancements have been validated through multiple peer-reviewed publications and featured in reputable media outlets. Such recognition reinforces the reliability and innovative nature of its technology, contributing to a solid reputation within the biotechnology community.

Competitive Landscape and Market Positioning

Operating within the competitive biotechnology and tissue engineering landscape, Organovo differentiates itself through its unique capability to recreate human physiological conditions with high fidelity. While the industry is marked by rapid technological advancements and intense research activity, Organovo’s focus on structurally and functionally relevant tissue models provides a compelling value proposition. The company’s collaborations with research institutions and its continued pursuit of functional tissue applications have established it as a key player in the niche market of advanced therapeutic research tools.

Applications in Drug Discovery and Medical Research

Organovo’s 3D human tissue technology is explicitly designed to serve two critical areas: medical research and drug discovery. In the context of drug development, the platform enables the creation of disease-specific models, thereby assisting researchers in evaluating drug responses in environments that accurately reflect human biology. This not only streamlines the process of determining therapeutic viability but also assists in identifying potential adverse reactions early in the development phase. By bridging the gap between traditional cell culture methods and animal models, Organovo’s approach contributes significantly to reducing the translational gap in modern pharmacological research.

Scientific Integrity and Long-Term Relevance

The expertise behind Organovo is underpinned by rigorous scientific research and continual innovation. Its work is well-documented in scientific literature and has been the subject of numerous case studies, which further substantiate the effectiveness of its engineered tissues. The company maintains a neutral, research-driven perspective, offering comprehensive insights into its methodologies without resorting to promotional or speculative language. This commitment to scientific integrity ensures that the information remains relevant and accurate over the long term.

Conclusion

In summary, Organovo Holding stands as a noteworthy contributor to the fields of biotechnology and medical research. Through its cutting-edge 3D tissue engineering technology, the company addresses fundamental challenges in drug discovery and therapeutic development. Its well-established partnerships, robust scientific foundation, and innovative clinical research applications underscore its importance within a rapidly evolving industry. For investors and researchers seeking detailed, unbiased insights into the company’s operations and business model, Organovo provides a compelling case study in the practical application of advanced tissue engineering for medical advancements.

News
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Organovo Holdings, Inc. (NASDAQ: ONVO) has announced its clinical program for FXR314, an FXR agonist that has completed initial trials with positive safety and tolerability results. The drug is approved for a Phase 2 trial targeting ulcerative colitis. The company emphasizes that FXR314 could be a superior option compared to existing FXR-directed therapies, aiming to minimize dose-limiting toxicity. Additionally, the company updated its timeline, moving the start of Phase 1 trials to 2025, with further guidance on Phase 2 forthcoming. Organovo specializes in developing therapies utilizing advanced 3D human tissue models.

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Organovo Holdings (ONVO) has achieved a significant milestone in developing a three-dimensional model for inflammatory bowel disease (IBD), particularly Crohn's disease. The model has been validated for target identification and therapeutic opportunities, demonstrating the ability to reproduce disease characteristics and reduce symptoms through targeted treatments. Organovo aims to advance at least one target to medicinal chemistry by the end of 2022, seeking to create a proprietary drug for Crohn's disease, a condition affecting over 1 million individuals in North America.

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Organovo Holdings, focusing on innovative 3D tissue models for drug development, announced Executive Chairman Keith Murphy's participation in the H.C. Wainwright 24th Annual Global Investment Conference from September 12-14, 2022. The company aims to advance drug development for Crohn’s Disease, having recently established its first 3D tissue model. A corporate presentation will be webcast on September 12, 2022, at 7:00 AM ET. Investors can access the archived presentation on Organovo's website for 90 days.

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Organovo Holdings (ONVO) announces the postponement of its 2022 Annual Meeting from September 7 to October 12, 2022, at 9:00 AM PT. This decision was made after the company received less than 35% of proxies by the previous record date, July 15, 2022. The new record date is set for September 7, 2022. The meeting will be conducted virtually to enhance stockholder participation. An amended proxy statement will be filed promptly with the SEC, providing updated information regarding the meeting.

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Organovo Holdings, Inc. (Nasdaq: ONVO) has successfully advanced its first inflammatory bowel disease (IBD) model for Crohn’s disease, marking a significant step in drug discovery. The model demonstrates key aspects of patient biology and is positioned to identify therapeutics. The company aims to complete target validation by March 2023, with a goal to file for an investigational new drug (IND) application by 2025. Organovo is positioning itself to leverage its 3D tissue technologies for innovative drug development, focusing on several pipeline programs for IBD.

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Organovo Holdings (Nasdaq: ONVO) has announced a licensing agreement with BICO, allowing the latter to utilize Organovo's foundational patent portfolio in 3D bioprinting. This collaboration marks a significant step, as it resolves previous legal disputes over potential patent infringements. Under this agreement, all civil actions regarding these patents are dismissed. The partnership aims to enhance the capabilities of BICO's product lines, facilitating further advancements in 3D bioprinting technology.

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Organovo Holdings (Nasdaq: ONVO) has partnered with BICO, granting them a broad license to its foundational patents in 3D bioprinting. This agreement resolves prior legal disputes between the two companies regarding patent infringement. Organovo's technology aims to create customized 3D human tissues for drug development, focusing on complex disease models. The company views this partnership as a significant move to broaden the impact of its bioprinting technology and support the growth of BICO's product lines.

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Organovo Holdings, Inc. (Nasdaq: ONVO) announced the granting of a stock option for 50,000 shares to a new employee, under the 2021 Inducement Equity Incentive Plan. The option has an exercise price of $2.75 per share and a vesting schedule over four years. This move is part of the company’s efforts to attract talent while complying with Nasdaq Listing Rule 5635(c)(4). Organovo is focused on creating 3D human tissues for drug development, utilizing innovative technology to replicate essential characteristics of human biology.

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Organovo Holdings, Inc. (Nasdaq: ONVO) has appointed Curtis Tyree, PhD, as the new Sr. Vice President of Strategy and Business Development. Dr. Tyree brings over 20 years of R&D and management experience from firms like Ligand Pharmaceuticals and HUYABIO International. His expertise is expected to enhance Organovo's strategic initiatives, especially in advancing drug development programs for ulcerative colitis and Crohn’s disease using 3D bioprinting technology. The company focuses on creating 3D human tissues as models for drug development.

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Organovo Holdings (ONVO) announced that two of its patents have successfully withstood a challenge, bolstering its robust intellectual property portfolio in 3D bioprinting. The company anticipates generating millions in licensing revenue from these patents through FY2022 to FY2025, aiding drug development costs for inflammatory bowel disease treatments. With strong patent claims recognized by third parties, Organovo's management aims to leverage its assets to benefit shareholders and explore new revenue opportunities.

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FAQ

What is the current stock price of Organovo Holding (ONVO)?

The current stock price of Organovo Holding (ONVO) is $2.24 as of March 31, 2025.

What is the market cap of Organovo Holding (ONVO)?

The market cap of Organovo Holding (ONVO) is approximately 4.6M.

What is Organovo Holding's primary focus?

Organovo designs and creates functional 3D human tissues for medical research and therapeutic applications, enabling advanced drug discovery.

How does Organovo generate revenue?

The company primarily generates revenue by collaborating with pharmaceutical and academic partners, licensing its proprietary 3D tissue engineering technology for preclinical research.

What distinguishes Organovo's 3D tissue engineering technology?

Its technology replicates native human tissue architecture and function, providing realistic disease models that enhance the drug discovery process.

What is FXR314 and why is it significant?

FXR314 is a drug candidate developed by Organovo for the treatment of inflammatory bowel diseases, showcasing the potential of applying engineered 3D tissues in clinical research.

Who are Organovo's typical partners?

Organovo partners with pharmaceutical companies, biopharma entities, and academic institutions to develop and validate its advanced tissue models.

How has Organovo been recognized in the media?

The company’s work has been featured in reputable publications such as The Wall Street Journal, Time Magazine, and The Economist, reflecting its impact on the biotechnology field.

What challenges does Organovo face?

Organovo navigates complex regulatory environments, technological competition, and the inherent challenges of replicating intricate human tissue environments.

How does Organovo contribute to the drug discovery process?

By creating accurate human disease models, Organovo's technology speeds up preclinical testing and aids in early detection of drug efficacy and safety, thereby streamlining the drug development pipeline.
Organovo Holding

Nasdaq:ONVO

ONVO Rankings

ONVO Stock Data

4.59M
1.77M
1.53%
12.21%
7.88%
Biotechnology
Biological Products, (no Disgnostic Substances)
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United States
SAN DIEGO