Welcome to our dedicated page for Oncolytics Biotech Common Shares news (Ticker: ONCY), a resource for investors and traders seeking the latest updates and insights on Oncolytics Biotech Common Shares stock.
Oncolytics Biotech Inc. (symbol: ONCY) is a pioneering biotechnology company dedicated to the development of oncolytic viruses as innovative cancer therapeutics. Their flagship product, pelareorep, is a unique immunotherapeutic agent designed to harness the power of the human reovirus to enhance the body's immune response against cancer. Pelareorep has shown promising potential in making tumors more responsive to a variety of oncology treatments by promoting an inflamed tumor phenotype.
The company's robust clinical development pipeline includes multiple human trials targeting some of the most prevalent cancers, such as breast, gastrointestinal, and pancreatic cancers. Notably, Oncolytics is conducting a Phase III trial for head and neck cancers and has several ongoing trials in advanced stages, including the GOBLET study, which explores the efficacy of pelareorep in combination with different chemotherapy regimens.
In breast cancer, Oncolytics is advancing towards registration-enabling studies for HR+/HER2- metastatic breast cancer, supported by compelling data from the BRACELET-1 and IND-213 randomized studies. The company is also making significant strides in pancreatic cancer research, recently receiving a US$5 million grant from the Pancreatic Cancer Action Network (PanCAN) for a new Phase 1/2 cohort in the GOBLET study, assessing pelareorep in combination with modified FOLFIRINOX and atezolizumab (Tecentriq®).
Financially, Oncolytics is well-positioned with a strong balance sheet and ongoing support from strategic partnerships and grants. The company’s collaborations with leading research institutions and oncology networks enhance its clinical programs and accelerate the development of pelareorep as a versatile cancer therapy. Oncolytics continues to innovate and push the boundaries of cancer treatment, aiming to bring new hope to patients worldwide.
Oncolytics Biotech (NASDAQ: ONCY) announced a conference call on August 11, 2022, at 8:30 a.m. ET to discuss Q2 financial results and corporate updates. Pelareorep, its lead therapeutic agent, is under evaluation in clinical trials targeting various cancers, including metastatic breast cancer. The company emphasizes the potential of pelareorep in enhancing immune responses and its synergy with other oncology treatments. However, risks such as funding availability and the efficacy of pelareorep may impact future outcomes.
Oncolytics Biotech has announced positive results from the phase 1b portion of its GOBLET study for pancreatic cancer, showing partial responses in all patients (n=3). The study evaluated pelareorep combined with chemotherapy and an anti-PD-L1 checkpoint inhibitor, meeting the criteria for expansion to additional patients. An independent review reported no toxicity concerns, suggesting potential for improved treatment approaches in pancreatic cancer, which has limited standard treatment efficacy. The findings will be featured at the ESMO World Congress on Gastrointestinal Cancer.
Oncolytics Biotech Inc. (NASDAQ: ONCY) held its Annual General Meeting (AGM) on June 16, 2022, with a shareholder turnout of 40.43%. James T. Parsons was elected to the Board of Directors, replacing Leonard Kruimer who did not seek re-election. Mr. Parsons, a seasoned executive with over 20 years in the life sciences sector, previously served as CFO at Trillium Therapeutics before its acquisition by Pfizer for $2.2 billion. The meeting also approved all resolutions, including the number of directors and the appointment of auditors for the upcoming year.
Oncolytics Biotech (NASDAQ: ONCY) has announced that Dr. Matt Coffey, President and CEO, will participate in a fireside chat at the 2022 RBC Capital Markets Global Healthcare Conference on May 18, 2022, at 11:00 a.m. ET. The conference will be held at the InterContinental New York Barclay. A live webcast of the presentation will be available on the company’s Investor Relations page and archived until August 15, 2022. Oncolytics is developing pelareorep, an immunotherapeutic agent aimed at treating various cancers.
Oncolytics Biotech announced key operational highlights and financial results for Q1 2022, with a cash position of $39.5 million expected to fund upcoming milestones. The company reported positive clinical data for its lead drug, pelareorep, showing improved patient outcomes in HR+/HER2- breast cancer and successful combinations with CAR T therapies in preclinical studies. Operating expenses decreased from $3.1 million to $2.6 million year-over-year, though net loss increased to $6.8 million. Upcoming milestones include data from the BRACELET-1 study in Q4 2022.
On May 4, 2022, Oncolytics Biotech announced favorable results from its AWARE-1 study on pelareorep for HR+/HER2- breast cancer. The treatment demonstrated a 100% favorable Risk of Recurrence Score (ROR-S) in evaluable patients, up from 55% at baseline. Increases in tumor cell death markers and T cell activation were also noted. The study's findings support pelareorep's potential to enhance clinical outcomes by transforming tumors into less aggressive types. Future clinical trials, including BRACELET-1, aim to further evaluate its effectiveness.
Oncolytics Biotech Inc. (NASDAQ: ONCY) has announced that its abstract, detailing results from the AWARE-1 study, has been accepted for presentation at the European Society for Medical Oncology Breast Cancer Meeting from May 3-5, 2022, in Berlin. The study evaluated the oncolytic virus pelareorep combined with letrozole and atezolizumab in early-stage breast cancer patients. Results suggest pelareorep may enhance immune responses and improve treatment outcomes. The presentation is scheduled for May 4, 2022, at 12:15 p.m. CET, focusing on innovative cancer therapies.
Oncolytics Biotech Inc. (NASDAQ: ONCY) will host a conference call and webcast on May 5, 2022, at 5:00 p.m. ET to discuss its first-quarter financial results and corporate update. Pelareorep, an immunotherapeutic agent being developed by Oncolytics, is under evaluation for its efficacy in treating various cancers. The company is moving towards a registration study for metastatic breast cancer and is conducting clinical trials in combination with other therapies. Investors can access the webcast via the Investor Relations page on Oncolytics' website.
Oncolytics Biotech Inc. (NASDAQ: ONCY) announced that CEO Dr. Matt Coffey will present a corporate overview at the Bloom Burton & Co. Healthcare Investor Conference on May 3, 2022, at 11:00 a.m. ET in Toronto. The conference will feature updates from Canadian healthcare companies and offer one-on-one investor meetings. A live webcast of the presentation will be available on Oncolytics' Investor Relations page and archived for three months. The company focuses on developing the immunotherapeutic agent pelareorep to enhance anti-cancer immune responses.
Oncolytics Biotech Inc. (NASDAQ: ONCY) announced the publication of preclinical data showing that pelareorep significantly enhances the efficacy of CAR T cell therapy in treating solid tumors. The study, published in Science Translational Medicine, demonstrates that pelareorep-loaded CAR T cells exhibit improved persistence and anti-cancer activity in various murine solid tumor models. This combination may address key challenges faced by CAR T therapies in solid tumors, potentially increasing treatment options for patients. The findings suggest a promising avenue for clinical application.