Oncocyte to Present New Data on DetermaIO™ from NeoTRIPaPDL1 Trial in Oral Presentation from Late-Breaking Abstract at ESMO 2021

Rhea-AI Summary

Oncocyte Corporation (Nasdaq: OCX) announced the first evaluation of its DetermaIO™ assay in a randomized clinical trial for triple-negative breast cancer (TNBC). This groundbreaking study will be presented at the European Society for Medical Oncology (ESMO) Congress from September 16-21, 2021. The late-breaking oral presentation, titled Predictive value of gene-expression profiles in the Neo TRIPaPDL1 trial, will occur on September 20 at 1:30 PM EST. DetermaIO aims to predict patient responses to immuno-oncology therapies, enhancing treatment decision-making.

Data represents first evaluation of DetermaIO in gold-standard randomized clinical trial in triple negative breast cancer

IRVINE, Calif., Sept. 13, 2021 (GLOBE NEWSWIRE) -- Oncocyte Corporation (Nasdaq: OCX), a precision diagnostics and monitoring company with the mission to improve patient outcomes by providing clear insights that inform critical decisions in the diagnosis, treatment, and monitoring of cancer, announced today that it will present new data from ongoing clinical research evaluating the 27-gene DetermaIO™ assay used to determine the likelihood of response to IO therapies at the upcoming European Society for Medical Oncology (ESMO) Congress, taking place virtually September 16^th-21^st, 2021.

Details for the late-breaking oral presentation:

Title: Predictive value of gene-expression profiles (GEPs) in the Neo TRIPaPDL1 trial
Abstract #: LBA12
Session type: Late-breaking abstract and oral presentation
Presenter: Giampaolo Bianchini, M.D., Head of the Breast Cancer Group at the San Raffaele Scientific Institute and lead investigator of the NeoTRIPaPDL1 trial
Authors: Bianchini, G., et al.
Date and time: Monday, September 20^th, 2021 at 1:30PM EST

The abstract will be available online at the ESMO 2021 website on Friday, September 17^th, 2021 at 6:05AM EST. Oncocyte will be distributing a data press release after market close on September 20^th, 2021, summarizing the presented results.

Additionally, on Tuesday, September 28^th, 2021 from 1-2PM EST, the Company will be hosting a Key Opinion Leader event with Dr. Bianchini and Priyanka Sharma, M.D., Professor of Medicine at the University of Kansas Medical Center to discuss the unmet need for identifying patients with triple-negative breast cancer (TNBC) who will respond to immunotherapy, with Dr. Bianchini highlighting the NeoTRIP randomized clinical trial ESMO data.

The Company’s DetermaIO assay is a precision diagnostic designed to determine the likelihood of response to IO therapies, and is the first and only test to measure the entire tumor microenvironment (TME). By evaluating the entire TME, the test can help identify patients that are primed to respond to IO therapy, as well as patients who may not respond as well, allowing for physicians and their patients to have data-driven conversations about the choices available to them. Previous studies presented and published support DetermaIO’s predictive utility in lung, bladder, and triple negative breast cancer, suggesting a pan-cancer utility in both primary and metastatic settings.

About Oncocyte
Oncocyte is a precision diagnostics and monitoring company with the mission to improve patient outcomes by providing clear insights that inform critical decisions in the diagnosis, treatment, and monitoring of cancer. The Company, through its proprietary tests and pharmaceutical services business, aims to help save lives by accelerating the diagnosis of cancer and advancing cancer care. The Company’s tests are designed to help provide clarity and confidence to physicians and their patients at every stage. DetermaRx™ identifies early-stage lung cancer patients who are at high risk for cancer recurrence and who may benefit from adjuvant chemotherapy. DetermaIO™, a gene expression test currently used as a research-use only tool, assesses the tumor microenvironment to predict response to immunotherapies. The Company’s pipeline of tests in development also includes DetermaTx™, which will assess mutational status of a tumor, blood-based monitoring test DetermaCNI™, and long-term recurrence monitoring test DetermaMx™. In addition, Oncocyte’s pharmaceutical services provide companies that are developing new cancer treatments a full suite of molecular testing services to support the drug development process.

DetermaRx™, DetermaIO™, DetermaTx™, DetermaCNI™ and DetermaMx™ are trademarks of Oncocyte Corporation.

Investor Contact

Bob Yedid
LifeSci Advisors, LLC
646-597-6989
bob@lifesciadvisors.com

Media Contact

Terri Clevenger
Westwicke/ICR Healthcare PR
Tel: 203.856.4326
Terri.Clevenger@icrinc.com

FAQ

What is the purpose of Oncocyte's DetermaIO assay in the TNBC trial?

DetermaIO is designed to determine the likelihood of response to immuno-oncology therapies in triple-negative breast cancer.

When will Oncocyte present data from the Neo TRIPaPDL1 trial?

Data from the Neo TRIPaPDL1 trial will be presented on September 20, 2021, at 1:30 PM EST.

What is the significance of the ESMO Congress for Oncocyte?

The ESMO Congress is significant as it is the venue for Oncocyte to present the first evaluation of DetermaIO in a randomized clinical trial.

When will the abstract for the DetermaIO presentation be available?

The abstract will be available online on September 17, 2021, at 6:05 AM EST.

Who is leading the presentation on the DetermaIO assay?

Dr. Giampaolo Bianchini, Head of the Breast Cancer Group at the San Raffaele Scientific Institute, will lead the presentation.

What other events will Oncocyte host related to the trial results?

Oncocyte will host a Key Opinion Leader event on September 28, 2021, to discuss the trial data.