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NextCure, Inc. - NXTC STOCK NEWS

Welcome to our dedicated page for NextCure news (Ticker: NXTC), a resource for investors and traders seeking the latest updates and insights on NextCure stock.

NextCure, Inc. (Nasdaq: NXTC) is a clinical-stage biopharmaceutical company dedicated to discovering and developing novel immunomedicines aimed at treating cancer and other immune-related diseases by restoring normal immune function. The company’s leading product candidate, NC318, is currently in Phase 2 clinical trials for advanced or metastatic solid tumors. NextCure is also advancing NC410, a novel immunomedicine designed to block immune suppression mediated by the immune modulator LAIR-1, and LNCB74, an ADC targeting B7-H4, a clinically validated cancer target. The company's pipeline includes additional antibodies in preclinical development targeting novel immune modulators expressed in inflamed tissue and tumor microenvironments across various cancer types.

NextCure has established significant partnerships including a license agreement with Yale University and a research collaboration with LigaChem Biosciences. Recent updates in their clinical pipeline include promising preclinical data on NC605 for preventing bone loss in patients with severe spinal cord injuries and the publication of a manuscript on the FLRT3-UNC5B pathway as a novel T cell checkpoint in cancer immunotherapy. Their innovative FIND-IO platform continues to discover new immunomedicine targets, expanding their therapeutic potential beyond oncology to chronic inflammatory diseases like COPD.

Financially, NextCure has a solid runway extending into the second half of 2026, focusing resources on high-priority programs such as NC410 in combination therapies and LNCB74, while seeking partners for other clinical and preclinical assets. The company's goal is to address unmet medical needs by providing new treatments for patients who do not respond to existing therapies or experience disease progression, leveraging scientific insights into biological pathways, cell interactions, and tumor microenvironments.

For the latest updates, visit www.nextcure.com

Rhea-AI Summary

NextCure, a clinical-stage biopharmaceutical company, reported its first-quarter 2024 financial results and provided a business update. They highlighted presenting Phase 1b data for NC410 combo with pembro at the ASCO Annual Meeting, showcasing preclinical data from LNCB74 at the AACR Annual Meeting, and having cash of approximately $96.0 million to fund operations into the second half of 2026. The company is focused on developing novel cancer therapies.

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NextCure, Inc. (NXTC) will present Phase 1b data of NC410 in combination with pembrolizumab at ASCO 2024. The clinical trial investigator will showcase results from a study on immune checkpoint inhibitors in colorectal and ovarian cancer patients.
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NextCure, Inc. presents promising preclinical data on LNCB74, a B7-H4-targeting ADC developed in partnership with LigaChem Biosciences. The data highlights LNCB74's high affinity for B7-H4, potent cytotoxicity in cancer cells, favorable pharmacokinetics, and strong anti-tumor activity in various tumor models. Key findings reveal improved safety, durable tumor regression, excellent tolerability in monkeys, and promising pharmacokinetic profile.
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NextCure, Inc. (NXTC) appoints Dr. Rakesh Dixit to its Scientific Advisory Board, a renowned expert in antibody-drug conjugates. Dr. Dixit's vast experience in developing ADCs will strengthen NextCure's proprietary ADCs, particularly LNCB74 for B7-H4. With a background in top biotech and pharma companies, Dr. Dixit's appointment signifies a significant step in advancing NextCure's therapeutic programs.
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NextCure, Inc. (NXTC) to present at the 23rd Annual Needham Virtual Healthcare Conference on April 11th, 2024, showcasing its commitment to developing innovative cancer therapies.
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NextCure, Inc. provided a business update, focusing on NC410 and LNCB74 therapies for ovarian and colorectal cancers. The company reported positive clinical data, financial results, and operational restructuring. Cash reserves of $108 million are expected to fund operations until the second half of 2026.
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NextCure, Inc. (NXTC) announces the publication of a manuscript detailing the FLRT3-UNC5B Checkpoint Pathway's role in inhibiting T cell-based cancer immunotherapies. The study reveals FLRT3's function as an inhibitor of T cell activity and the potential of a FLRT3 monoclonal antibody to reverse these effects, offering new therapeutic avenues for cancer treatment.
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NextCure, Inc. (NXTC) presented preclinical data on a humanized monoclonal antibody targeting VSTM-1 for treating inflammatory airway disorders like COPD. The antibody has shown promise in reducing inflammation and preventing disease in animal models. NextCure is planning additional preclinical models and combination studies for other indications.
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NextCure, Inc. (Nasdaq: NXTC) announced the publication of a manuscript demonstrating the potential of NC605, a novel anti-Siglec-15 (S15) antibody, to prevent bone loss and preserve bone strength in animal models of severe immobilization resulting from acute spinal cord injury.
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NextCure, Inc. (Nasdaq: NXTC) provided an update on its clinical pipeline, including progress on NC410, LNCB74, NC762, and NC525. The company is actively seeking strategic partners to accelerate global development of its programs.
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FAQ

What is the current stock price of NextCure (NXTC)?

The current stock price of NextCure (NXTC) is $0.97 as of December 20, 2024.

What is the market cap of NextCure (NXTC)?

The market cap of NextCure (NXTC) is approximately 26.8M.

What is NextCure, Inc. known for?

NextCure, Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing novel immunomedicines to treat cancer and other immune-related diseases.

What are the key products in development at NextCure?

Key products include NC318, NC410, and LNCB74, all aimed at treating various cancers through novel mechanisms targeting immune modulation.

What partnerships does NextCure have?

NextCure has partnerships with Yale University for licensing and LigaChem Biosciences for research and development collaborations.

What is NC318?

NC318 is NextCure’s lead product candidate, currently in Phase 2 clinical trials for the treatment of advanced or metastatic solid tumors.

How does NC410 work?

NC410 is a novel immunomedicine designed to block immune suppression mediated by the leukocyte-associated immunoglobulin-like receptor 1 (LAIR-1).

What recent achievements has NextCure made?

Recent achievements include promising preclinical data for NC605 in preventing bone loss due to spinal cord injuries and a publication on the FLRT3-UNC5B pathway in cancer immunotherapy.

What is the FIND-IO platform?

The FIND-IO platform is NextCure’s proprietary technology for discovering new immunomedicine targets, which helps in developing therapies for oncology and chronic inflammatory diseases.

What is LNCB74?

LNCB74 is an antibody-drug conjugate (ADC) targeting B7-H4, developed in collaboration with LigaChem Biosciences, showing strong preclinical safety and anti-tumor activity.

What is NextCure’s financial outlook?

NextCure has a financial runway extending into the second half of 2026, with focused resources on priority programs and seeking partners for other assets.

Where can I find the latest updates on NextCure?

The latest updates can be found on their website at www.nextcure.com.

NextCure, Inc.

Nasdaq:NXTC

NXTC Rankings

NXTC Stock Data

26.77M
24.38M
8.85%
57.52%
0.26%
Biotechnology
Pharmaceutical Preparations
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