Welcome to our dedicated page for Intellia Therapeutics news (Ticker: NTLA), a resource for investors and traders seeking the latest updates and insights on Intellia Therapeutics stock.
Intellia Therapeutics, Inc. (NASDAQ: NTLA) is a pioneering clinical-stage gene editing company dedicated to revolutionizing medicine through the use of CRISPR-based therapies. Founded in 2014 by Caribou Biosciences and Atlas Venture, along with leading scientists in the field, Intellia harnesses the potential of CRISPR/Cas9 technology to develop curative treatments for a variety of genetically defined diseases.
The company's core mission is to leverage CRISPR/Cas9—an innovative technology adapted from a natural cellular process that allows for precise and flexible gene editing. This technology enables the correction of specific DNA sequences within any organism, opening new frontiers in biomedical research and clinical interventions.
Intellia's portfolio includes both in vivo and ex vivo gene editing programs. The in vivo programs aim to edit disease-causing genes directly within the human body, targeting conditions such as ATTR amyloidosis, hereditary angioedema (HAE), and alpha-1 antitrypsin deficiency. Notable achievements include the interim results from their NTLA-2002 program for HAE, which showed a 95% reduction in monthly attack rates, with most patients remaining attack-free.
The ex vivo programs focus on engineering human cells outside the body to treat cancer and autoimmune diseases. These programs include collaborations with prominent companies like Regeneron and Novartis, which help advance their therapeutic pipeline.
Intellia's financial condition reflects its robust pipeline and strategic partnerships. The company recently reported strong enrollment progress in their pivotal Phase 3 MAGNITUDE trial for NTLA-2001 targeted at ATTR amyloidosis with cardiomyopathy. They have also formed a strategic collaboration with ReCode Therapeutics to develop treatments for cystic fibrosis, utilizing ReCode's Selective Organ Targeting (SORT) lipid nanoparticle delivery platform.
Committed to advancing the field of gene editing, Intellia continues to expand its CRISPR-based platform with novel editing and delivery technologies. The company remains at the forefront of a new era in medicine, as evidenced by its ongoing clinical trials and promising preliminary data.
For more detailed information and the latest updates, investors and stakeholders are encouraged to visit www.intelliatx.com and follow Intellia on Twitter @intelliatx.
Intellia Therapeutics has made significant strides in its CRISPR gene-editing programs, with promising interim Phase 1 data for NTLA-2001 showing a maximum 96% reduction in serum TTR levels for ATTR amyloidosis. The company is poised to initiate Phase 1 trials for NTLA-2002 and NTLA-5001 this year. Financially, Intellia ended Q2 2021 with $551.3 million in cash and raised an additional $648.1 million from a follow-on offering. Despite a net loss of $68.8 million, Intellia's strong financial position supports ongoing and future development efforts.
Intellia Therapeutics (NASDAQ:NTLA) will present its Q2 2021 financial results and operational highlights on August 5, 2021, at 8 a.m. E.T. The conference call will provide insights into its progress in developing CRISPR/Cas9-based therapeutics. Interested participants can join via U.S. or international dialing, with a live webcast available. A replay will be accessible on Intellia's website starting noon E.T. on the same day. The company focuses on curative therapies using both in vivo and ex vivo genome editing techniques.
Intellia Therapeutics (NASDAQ:NTLA) has completed a public offering of 4,758,620 shares at $145.00 each, raising approximately $690 million, following the full exercise of the underwriters' option for 620,689 additional shares. The offering was managed by Goldman Sachs, Jefferies, SVB Leerink, and Barclays. Shares were offered under a shelf registration statement effective with the SEC. This capital is expected to support the development of Intellia's CRISPR/Cas9-based therapeutics. The press release includes forward-looking statements subject to market uncertainties.
Intellia Therapeutics (NASDAQ:NTLA) announced the pricing of a public offering of 4,137,931 shares at $145.00 per share, aiming to raise approximately $600 million before expenses. The offering includes a 30-day option for underwriters to purchase up to an additional 620,689 shares. The offering is set to close around July 2, 2021, subject to conditions. Goldman Sachs, Jefferies, SVB Leerink, and Barclays are the joint managers for this offering, which is conducted under an effective SEC shelf registration statement.
Intellia Therapeutics (NASDAQ:NTLA) announced a public offering of $400 million in common stock, with an option for underwriters to purchase an additional 15%. The company aims to utilize proceeds for advancing its CRISPR/Cas9 genome editing technology. Goldman Sachs & Co. LLC, Jefferies, SVB Leerink, and Barclays are joint book-running managers for the offering. The offering is contingent on market conditions and may change. The shares will be sold under an effective registration statement filed with the SEC, ensuring compliance with securities laws.
Intellia Therapeutics and Regeneron Pharmaceuticals announced promising interim results from a Phase 1 trial of NTLA-2001 for treating hereditary transthyretin amyloidosis (ATTRv-PN). The single 0.3 mg/kg dose led to an impressive 87% mean reduction in serum TTR levels, with a maximum reduction of 96% observed by day 28. The treatment showed a favorable safety profile, with no serious adverse events reported among the first six patients. Data was published in The New England Journal of Medicine and presented at the Peripheral Nerve Society Annual Meeting. Future expansions of the trial are planned.
Intellia Therapeutics (NTLA) announced promising interim results from its Phase 1 trial of NTLA-2001, the first in vivo CRISPR genome editing therapy for hereditary transthyretin amyloidosis with polyneuropathy. A 0.3 mg/kg dose led to an 87% mean reduction in serum TTR levels, peaking at 96% by day 28. The treatment exhibited a favorable safety profile with no serious adverse events in the first six patients. These findings, published in The New England Journal of Medicine, highlight NTLA-2001's potential as a single-dose therapy that could transform treatment outcomes for this serious condition.
Intellia Therapeutics (NASDAQ: NTLA) has appointed James Basta as Executive Vice President, General Counsel, and Corporate Secretary. With over 25 years of legal experience, Basta previously served as Chief Legal Officer at Kura Oncology and held significant roles at Biogen. He succeeds José Rivera, a founding employee, who will assist during the transition. Intellia's leadership believes Basta's expertise will bolster their mission to develop curative genome editing therapies. Forward-looking statements address potential risks in advancing their CRISPR/Cas9 technology and pipeline.
Blackstone (NYSE: BX) has announced a $250 million investment to establish a new CAR T-cell therapy company alongside Intellia Therapeutics (NASDAQ: NTLA) and Cellex. This venture will feature a blend of GEMoaB's advanced CAR-T technology and Intellia's CRISPR genomic engineering. Aimed at improving efficacy and safety across various cancers, the new company will be based in Cambridge, Massachusetts, with operations in Germany. Andrew Schiermeier will lead this initiative, focusing on providing innovative treatments for tough-to-treat cancers and autoimmune conditions.
Intellia Therapeutics (NASDAQ:NTLA) announced that interim Phase 1 data from its lead CRISPR therapy, NTLA-2001, will be presented on June 26. This therapy aims to treat transthyretin amyloidosis (ATTR) with a single, systemically administered dose. The ongoing trial targets hereditary ATTR amyloidosis with polyneuropathy. Initial results will assess safety and pharmacodynamics, presenting a potential breakthrough in treatment compared to the traditional lifelong therapies. Following the Phase 1 trial, further studies will evaluate NTLA-2001's effectiveness in a broader ATTR population.
FAQ
What is the current stock price of Intellia Therapeutics (NTLA)?
What is the market cap of Intellia Therapeutics (NTLA)?
What is the mission of Intellia Therapeutics?
What diseases is Intellia targeting with their CRISPR-based therapies?
What are Intellia's key advancements in hereditary angioedema (HAE) treatment?
When was Intellia Therapeutics founded?
Who are Intellia's key collaborators?
What is CRISPR/Cas9?
How does Intellia's in vivo program work?
What are the recent financial highlights of Intellia Therapeutics?
What is the scope of Intellia's collaboration with ReCode Therapeutics?
Where can I find more information about Intellia Therapeutics?
