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NanoString Announces the Launch of the Whole Transcriptome Atlas with Data to be Presented at the Third Annual Spatial Genomics Summit on February 23, 2021

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NanoString Technologies (NASDAQ:NSTG) announced the commercial launch of the Whole Transcriptome Atlas (WTA) for human and mouse tissue research, enhancing the GeoMx Digital Spatial Profiler (DSP) portfolio. The WTA provides a comprehensive view of all protein-coding genes and expands applications into neuroscience and developmental biology, complementing existing offerings in oncology and immunology. This launch signifies a key milestone for the company, with strong interest noted in its Technology Access Program. The WTA's capabilities will be showcased at the upcoming Spatial Genomics Summit on February 23.

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  • Launch of Whole Transcriptome Atlas (WTA) for human and mouse tissue research.
  • Expansion of applications into neuroscience and developmental biology.
  • Strong interest in the Technology Access Program highlights market demand.
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NanoString Technologies, Inc. (NASDAQ:NSTG), a leading provider of life science tools for discovery and translational research, today announced the commercial availability of the Whole Transcriptome Atlas (WTA) for research using human tissue and the GeoMx® Digital Spatial Profiler (DSP). In addition, NanoString is introducing the WTA for research using mouse tissue through its GeoMx Technology Access Program (TAP). These launches extend the GeoMx Atlas portfolio, which combine the power of spatial biology and Next Generation Sequencing, to enable full transcriptome spatial RNA and high-plex protein analysis on the GeoMx DSP.

The WTA provides an unbiased, spatial view of all protein-coding genes and is designed for NGS readout on Illumina sequencers. The WTA extends the GeoMx RNA Assay portfolio from a focus on oncology and immunology to new applications in neuroscience, developmental biology, and additional diverse fields. The WTA utilizes the same workflow and chemistry as other GeoMx Atlas products to enable robust and sensitive performance in formalin-fixed paraffin-embedded (FFPE) or Fresh Frozen samples. Complementary protein assays allow for a multi-omic view of spatial biology using GeoMx DSP.

“We applied the WTA to map the spatial context of gene expression in developing brains to better understand how substructures change over time. The high sensitivity of the WTA enabled us to not only map cells that we had identified in our single cell RNA-seq experiments, but also localize the cellular interactions that lead to substructure formation,” said Omer Bayraktar, Ph.D., Cellular Genetics Group Leader at the Wellcome Sanger Institute.

“The launch of WTA is a key milestone for NanoString, bringing unbiased RNA profiling to the GeoMx DSP portfolio,” said Brad Gray, president and chief executive officer of NanoString. “The strong enthusiasm for the products in our Technology Access Program highlights the appetite for whole transcriptome spatial analysis on GeoMx DSP.”

The commercial launch of the Whole Transcriptome Atlas will be highlighted at NanoString’s 3rd Annual Spatial Genomics Summit, to be held virtually on February 23. Data demonstrating the high sensitivity and robust performance of the WTA for human and mouse will be highlighted in several presentations from leading research institutions. The Spatial Genomics Summit has been held each February beginning in 2019 to showcase the rapidly evolving field of Spatial Genomics. This year’s event will include a panel of experts for the plenary roundtable discussion of “Research in the Spatial Genomics Era.” Panelists include Drs. Esperanza Anguiano from Bristol Myers Squibb, Omer Bayraktar of the Wellcome Sanger Institute, Evan Newell from the Fred Hutchinson Cancer Research Center and Peter Sorger of Harvard Medical School. The moderator of the panel is Stephane Budel, Ph.D., from DeciBio Consulting.

To learn more about NanoString’s GeoMx Digital Spatial Profiler, please visit https://www.nanostring.com/products/geomx-digital-spatial-profiler/geomx-dsp.

About NanoString Technologies, Inc.

NanoString Technologies is a leading provider of life science tools for discovery and translational research. The company’s nCounter® Analysis System is used in life sciences research and has been cited in more than 4,000 peer-reviewed publications. The nCounter Analysis System offers a cost-effective way to easily profile the expression of hundreds of genes, proteins, miRNAs, or copy number variations, simultaneously with high sensitivity and precision, facilitating a wide variety of basic research and translational medicine applications, including biomarker discovery and validation. The company’s GeoMx® Digital Spatial Profiler enables highly-multiplexed spatial profiling of RNA and protein targets in a variety of sample types, including FFPE tissue sections.

For more information, please visit www.nanostring.com.

NanoString, NanoString Technologies, the NanoString logo, GeoMx, and nCounter are trademarks or registered trademarks of NanoString Technologies, Inc. in various jurisdictions.

FAQ

What is the Whole Transcriptome Atlas (WTA) launched by NanoString?

The WTA provides an unbiased spatial view of all protein-coding genes for human and mouse tissue research.

How does the WTA benefit research in neuroscience?

The WTA enables comprehensive mapping of gene expression in developing brains, enhancing understanding of substructure formation.

When is the Spatial Genomics Summit showcasing the WTA?

The Spatial Genomics Summit will be held virtually on February 23.

What technologies does the GeoMx Digital Spatial Profiler support?

It supports high-plex protein analysis and whole transcriptome spatial RNA analysis.

What markets is the WTA expected to impact?

The WTA is expected to impact neuroscience, developmental biology, oncology, and immunology research.

NanoString Technologies, Inc.

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