NexImmune Reports First Quarter 2021 Financial Results and Recent Updates
NexImmune, Inc. (Nasdaq: NEXI) reported Q1 2021 results, highlighting a robust cash position following a $126M IPO in February 2021. The company is advancing NEXI-001 and NEXI-002, both in Phase 1/2 clinical trials, with preliminary data expected at upcoming scientific conferences. Cash and equivalents reached $118.1M, supporting operations through mid-2022. R&D expenses rose to $6.0M, largely due to clinical trial costs, while general and administrative expenses increased to $4.1M. The net loss for the quarter was $8.5M, or $0.71 per share, up from $6.3M year-over-year.
- Successful IPO raised $126M, oversubscribed, strengthening cash position.
- Sufficient capital to fund operations through mid-2022.
- Advancing two lead product candidates in Phase 1/2 trials.
- Net loss increased to $8.5M, worsened from $6.3M year-over-year.
- R&D expenses up to $6.0M, indicating higher costs.
- Advancing two lead product candidates in Phase 1/2 clinical trials
- Completed successful
$126M initial public offering (IPO) in February 2021 - Additional clinical and preclinical data anticipated in the second half of 2021
GAITHERSBURG, Md., May 17, 2021 (GLOBE NEWSWIRE) -- NexImmune, Inc. (Nasdaq: NEXI), a clinical-stage biotechnology company developing a novel approach to immunotherapy designed to orchestrate a targeted immune response by directing the function of antigen-specific T cells, today reported its financial results for the first quarter of 2021.
“With a strong cash position following our successful IPO in February, we remain focused on completing enrollment in our clinical trials for NEXI-001 and NEXI-002, and we expect to present additional clinical data at scientific conferences during 2021 for each,” said Scott Carmer, Chief Executive Officer. “We are also advancing new cell therapy programs targeting solid tumors and have initiated IND-enabling pre-clinical experiments that will support the initial application of our ‘AIM Injectable’ modality. We look forward to providing further updates as these important programs mature.”
Select 1Q 2021 Business Highlights
- On February 17, 2021, NexImmune completed a successful IPO and raised gross proceeds of
$126M . The IPO was oversubscribed and priced at the top of the range. - NexImmune announced the appointments of Robert Knight, MD as Chief Medical Officer; Jerome Zeldis, MD, PhD as Executive Vice President, Research and Development; Jeffery Weber, MD, PhD as Chief Scientific Advisor and Scientific Advisory Board Chair; Chad Rubin as SVP of Corporate Affairs; and Grant Verstandig as a member of its Board of Directors.
- NEXI-001 and NEXI-002 are both in Phase 1/2 clinical trials. The Company will share preliminary data from the initial safety cohorts of both trials at the 2021 ASCO Annual Meeting and EHA2021 Virtual Congress for NEXI-001 and NEXI-002, respectively, with additional results for each trial in Q421.
Select 1Q 2021 Financial Highlights
Cash and cash equivalents for the company as of March 31, 2021 were
Research and development expenses were
General and administrative expenses were
Net loss, according to generally accepted accounting principles in the U.S. (GAAP), was
About NexImmune
NexImmune is a clinical-stage biotechnology company developing a novel approach to immunotherapy designed to employ the body’s own T cells to generate a specific, potent, and durable immune response. The backbone of NexImmune’s approach is a proprietary Artificial Immune Modulation (AIM™) nanoparticle technology platform. The AIM technology enables NexImmune to construct nanoparticles that function as synthetic dendritic cells capable of directing a specific T cell-mediated immune response. AIM constructed nanoparticles employ natural biology to engage, activate and expand endogenous T cells in ways that combine anti-tumor attributes of antigen-specific precision, potency and long-term persistence with reduced potential for off-target toxicities.
NexImmune’s two lead programs, NEXI-001 and NEXI-002, are in Phase 1/2 clinical trials for the treatment of relapsed AML after allogeneic stem cell transplantation and multiple myeloma refractory to 3 or more prior lines of therapy, respectively. NexImmune is also developing new AIM nanoparticle constructs and modalities for potential clinical evaluation in oncology and in disease areas outside of oncology, including autoimmune disorders and infectious disease.
For more information, visit www.neximmune.com.
Forward Looking Statements
This press release may contain “forward-looking” statements within the meaning of the Private Securities Litigation Reform Act of 1995 that are based on the beliefs and assumptions and on information currently available to management of NexImmune, Inc. (the “Company”). All statements other than statements of historical fact contained in this press release are forward-looking statements, including statements concerning our results of operations for the three months ended March 31, 2021; the sufficiency of the Company’s current cash and cash equivalents to fund its planned operations through the second quarter of 2022; our planned and ongoing clinical studies for the Company’s product candidates, including NEXI-001 and NEXI-002; the initiation, enrollment, timing, progress, release of data from and results of those planned and ongoing clinical studies; and the utility of prior preclinical and clinical data in determining future clinical results. In some cases, you can identify forward-looking statements by terminology such as “may,” “will,” “should,” “expects,” “plans,” “anticipates,” “believes,” “estimates,” “predicts,” “potential” or “continue” or the negative of these terms or other comparable terminology. Forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause the Company’s actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. These risks and uncertainties include, but are not limited to, the risks and uncertainties set forth in the “Risk Factors” section of our Annual Report on Form 10-K for the year ended December 31, 2020 filed with the Securities and Exchange Commission (“SEC”) on March 31, 2021, and subsequent reports that we file with the SEC. Forward-looking statements represent the Company’s beliefs and assumptions only as of the date of this press release. Although the Company believes that the expectations reflected in the forward-looking statements are reasonable, it cannot guarantee future results, levels of activity, performance or achievements. Except as required by law, the Company assumes no obligation to publicly update any forward-looking statements for any reason after the date of this press release to conform any of the forward-looking statements to actual results or to changes in its expectations.
NEXIMMUNE, INC.
BALANCE SHEETS
| March 31, 2021 | December 31, 2020 | |||||||
| unaudited | ||||||||
| ASSETS | ||||||||
| Current assets: | ||||||||
| Cash and cash equivalents | $ | 118,102,945 | $ | 5,031,079 | ||||
| Restricted cash | 67,500 | 67,500 | ||||||
| Prepaid expenses and other current assets | 4,788,019 | 3,293,858 | ||||||
| Total current assets | 122,958,464 | 8,392,437 | ||||||
| Property and equipment, net | 3,584,412 | 2,885,260 | ||||||
| Other non-current assets | 23,373 | 23,373 | ||||||
| Total assets | $ | 126,566,249 | $ | 11,301,070 | ||||
| LIABILITIES, REDEEMABLE CONVERTIBLE PREFERRED STOCK AND STOCKHOLDERS’ DEFICIT | ||||||||
| Current liabilities: | ||||||||
| Accounts payable | $ | 2,406,537 | $ | 2,760,129 | ||||
| Accrued expenses | 2,842,998 | 2,603,027 | ||||||
| Derivative liability | — | 1,702,359 | ||||||
| Other current liabilities | 843,619 | 843,619 | ||||||
| Convertible notes issued to related parties | — | 7,324,267 | ||||||
| Convertible notes | — | 11,793,397 | ||||||
| Total current liabilities | 6,093,154 | 27,026,798 | ||||||
| Deferred rent, net of current portion | 11,764 | 23,529 | ||||||
| Other non-current liabilities | — | 4,935 | ||||||
| Total liabilities | 6,104,918 | 27,055,262 | ||||||
| Commitments and contingencies | ||||||||
| Redeemable convertible preferred stock | ||||||||
| Series A Redeemable Convertible Preferred Stock, | — | 35,047,435 | ||||||
| Series A-2 Redeemable Convertible Preferred Stock, Liquidation value of | — | 7,685,865 | ||||||
| Series A-3 Redeemable Convertible Preferred Stock, Liquidation value of | — | 10,887,449 | ||||||
| Total redeemable convertible preferred stock | — | 53,620,749 | ||||||
| Stockholders’ deficit | ||||||||
| Common Stock, | 2,258 | 126 | ||||||
| Additional paid-in-capital | 205,847,571 | 8,206,938 | ||||||
| Accumulated deficit | (85,388,498 | ) | (77,582,005 | ) | ||||
| Total stockholders’ deficit | 120,461,331 | (69,374,941 | ) | |||||
| Total liabilities, redeemable convertible preferred stock and stockholders’ deficit | $ | 126,566,249 | $ | 11,301,070 | ||||
NEXIMMUNE, INC.
STATEMENTS OF OPERATIONS
(unaudited)
| Three Months Ended March 31, | ||||||||
| 2021 | 2020 | |||||||
| Revenue | $ | — | $ | — | ||||
| Operating expenses: | ||||||||
| Research and Development | 6,012,608 | 4,272,167 | ||||||
| General and Administrative | 4,057,592 | 2,088,401 | ||||||
| Total operating expenses | 10,070,200 | 6,360,568 | ||||||
| Loss from operations | (10,070,200 | ) | (6,360,568 | ) | ||||
| Other (expense) income: | ||||||||
| Interest income | 3,613 | 18,684 | ||||||
| Interest expense | (904,119 | ) | (989 | ) | ||||
| Change in fair value of derivative liability | 2,424,877 | — | ||||||
| Other income (expense) | (722 | ) | 27,365 | |||||
| Other income (expense) | 1,523,649 | 45,060 | ||||||
| Net loss | $ | (8,546,551 | ) | $ | (6,315,508 | ) | ||
| Accumulated dividends on Redeemable Convertible Preferred Stock | (377,562 | ) | (815,516 | ) | ||||
| Net loss available to common stockholders’ | $ | (8,924,113 | ) | $ | (7,131,024 | ) | ||
| Basic and diluted net loss available to common stockholders per common share | $ | (0.71 | ) | $ | (5.68 | ) | ||
| Basic and diluted weighted-average number of common shares outstanding | 12,633,123 | 1,254,681 | ||||||
STATEMENTS OF COMPREHENSIVE LOSS
(unaudited)
| For the Three Months Ended March 31, | ||||||||
| 2021 | 2020 | |||||||
| Net loss | $ | (8,546,551 | ) | $ | (6,315,508 | ) | ||
| Other comprehensive loss: | ||||||||
| Unrealized (loss) gain on available-for-sale marketable securities, net of tax | — | (506 | ) | |||||
| Comprehensive loss | $ | (8,546,551 | ) | $ | (6,316,014 | ) | ||
Contacts
Investors:
Chad Rubin, SVP Corporate Affairs
NexImmune, Inc.
646.319.3261
crubin@neximmune.com
Media:
Mike Beyer
Sam Brown Inc. Healthcare Communications
312.961.2502
mikebeyer@sambrown.com
FAQ
What were NexImmune's financial results for Q1 2021?
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When will NexImmune present additional clinical data?
