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John Elway Teams Up with Endo to Share Update on Dupuytren's Contracture and Treatment with XIAFLEX® (collagenase clostridium histolyticum)

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Endo (OTCQX: NDOI) announced that NFL legend John Elway will provide an update about his experience with XIAFLEX® treatment for Dupuytren's contracture from five years ago. Elway, who partnered with Endo in 2019 for a disease education campaign, will speak to media outlets on November 20, 2024, about his patient journey and current hand health. He reports feeling early signs of the condition in another finger and plans to seek XIAFLEX treatment again. The company notes that Elway's involvement has successfully raised awareness about Dupuytren's contracture among patients and hand specialists.

Endo (OTCQX: NDOI) ha annunciato che la leggenda della NFL John Elway fornirà un aggiornamento sulla sua esperienza con il trattamento XIAFLEX® per la contrattura di Dupuytren di cinque anni fa. Elway, che ha collaborato con Endo nel 2019 per una campagna di educazione sulla malattia, parlerà con i media il 20 novembre 2024 riguardo il suo percorso come paziente e la sua attuale salute della mano. Riporta di percepire i primi segni della condizione in un altro dito e prevede di richiedere nuovamente il trattamento con XIAFLEX. La società sottolinea che il coinvolgimento di Elway ha contribuito a sensibilizzare i pazienti e gli specialisti delle mani sulla contrattura di Dupuytren.

Endo (OTCQX: NDOI) anunció que la leyenda de la NFL John Elway proporcionará una actualización sobre su experiencia con el tratamiento XIAFLEX® para la contractura de Dupuytren hace cinco años. Elway, quien se asoció con Endo en 2019 para una campaña de educación sobre la enfermedad, hablará con los medios el 20 de noviembre de 2024 sobre su trayectoria como paciente y su salud actual de la mano. Informa que siente signos tempranos de la condición en otro dedo y planea buscar nuevamente el tratamiento con XIAFLEX. La compañía señala que la participación de Elway ha elevado exitosamente la conciencia sobre la contractura de Dupuytren entre pacientes y especialistas de la mano.

Endo (OTCQX: NDOI)는 NFL 전설인 존 엘웨이가 5년 전 듀퍅트렌 수축증 치료를 위한 XIAFLEX® 경험에 대한 업데이트를 제공할 것이라고 발표했습니다. 2019년에 질병 교육 캠페인을 위해 Endo와 파트너십을 체결한 엘웨이는 2024년 11월 20일 언론 매체에 자신의 환자 여정과 현재 손 건강에 대해 이야기할 예정입니다. 그는 다른 손가락에서 상태의 초기 징후를 느끼고 있으며, 다시 XIAFLEX 치료를 받을 계획이라고 보고했습니다. 이 회사는 엘웨이의 참여가 듀퍅트렌 수축증에 대한 환자와 손 전문의 사이에서 인식을 성공적으로 높였다는 점을 강조했습니다.

Endo (OTCQX: NDOI) a annoncé que la légende de la NFL John Elway fera le point sur son expérience avec le traitement XIAFLEX® pour la contracture de Dupuytren datant de cinq ans. Elway, qui a collaboré avec Endo en 2019 pour une campagne d'éducation sur la maladie, s'exprimera devant les médias le 20 novembre 2024 au sujet de son parcours en tant que patient et de sa santé actuelle des mains. Il fait savoir qu'il ressent des signes précoces de la maladie dans un autre doigt et prévoit de demander à nouveau un traitement XIAFLEX. La société souligne que l'implication d'Elway a contribué à sensibiliser les patients et les spécialistes des mains à la contracture de Dupuytren.

Endo (OTCQX: NDOI) gab bekannt, dass die NFL-Legende John Elway ein Update zu seiner Erfahrung mit der XIAFLEX®-Behandlung der Dupuytren-Kontraktur vor fünf Jahren geben wird. Elway, der 2019 eine Partnerschaft mit Endo für eine Aufklärungskampagne eingegangen ist, wird am 20. November 2024 gegenüber den Medien über seinen Patientenweg und seine aktuelle Handgesundheit sprechen. Er berichtet, dass er frühe Anzeichen der Erkrankung in einem anderen Finger bemerkt und plant, erneut eine XIAFLEX-Behandlung in Anspruch zu nehmen. Das Unternehmen hebt hervor, dass Elways Engagement erfolgreich das Bewusstsein für die Dupuytren-Kontraktur unter Patienten und Handchirurgen erhöht hat.

Positive
  • Continued partnership with high-profile NFL legend John Elway enhances brand visibility
  • Patient testimonial confirms long-term effectiveness of XIAFLEX treatment
  • Successful disease awareness campaign increasing product recognition among specialists
Negative
  • None.

MALVERN, Pa., Nov. 20, 2024 /PRNewswire/ -- Endo, Inc. ("Endo") (OTCQX: NDOI) announced today that John Elway will share an update about his Dupuytren's contracture patient journey, including his treatment with XIAFLEX® (collagenase clostridium histolyticum) five years ago.

"It's been five years since I was treated with XIAFLEX for my Dupuytren's contracture, and people still talk to me about my hand health and ask for advice about the condition," said the legendary NFL quarterback. "I don't partner with many companies and brands, but I believe in this procedure and want to share my personal perspective with more people."

Elway will speak to several media outlets on November 20, 2024 to detail his patient journey and provide an update on his current hand health. He believes he is feeling the beginning of Dupuytren's contracture in another finger, and he plans to request treatment with XIAFLEX again.

"We know that real patient stories are powerful in the Dupuytren's community, and John Elway is making a major impact today by sharing his journey," said Stephanie Wenstrup, executive director at Endo. "We're proud that he is partnering with Endo to educate people about the condition and empower patients to find a hand specialist and ask about XIAFLEX."

Elway partnered with Endo in 2019 on a disease education campaign about Dupuytren's contracture. The company routinely hears from hand surgeons that he successfully built awareness about the condition.

"I had plenty of surgeries throughout my career, and that led me to wait—too long, in retrospect—to finally do something about my Dupuytren's contracture. I'm glad that I was able to receive a nonsurgical medication, XIAFLEX."

About Dupuytren's Contracture
Dupuytren's contracture is a lifelong condition that may get worse over time. It's caused by a buildup of collagen in the hand, which forms a rope-like cord that pulls fingers toward the palm so they can't be straightened. As Dupuytren's contracture progresses, it may become difficult for individuals to use their hand(s) for daily tasks and activities.

WHAT IS XIAFLEX®?

XIAFLEX is a prescription medicine used to treat adults with Dupuytren's contracture when a "cord" can be felt. It is not known if XIAFLEX is safe and effective in children under the age of 18.

IMPORTANT SAFETY INFORMATION FOR XIAFLEX

Do not receive XIAFLEX if you have had an allergic reaction to collagenase clostridium histolyticum or any of the ingredients in XIAFLEX, or to any other collagenase product. See the end of the Medication Guide for a complete list of ingredients in XIAFLEX.

XIAFLEX can cause serious side effects, including:

  • Tendon rupture or ligament damage. Receiving an injection of XIAFLEX may cause damage to a tendon or ligament in your hand and cause it to break or weaken. This could require surgery to fix the damaged tendon or ligament. Call your healthcare provider right away if you have trouble bending your injected finger (towards the wrist) after the swelling goes down or you have problems using your treated hand after your follow-up visit
  • Nerve injury or other serious injury of the hand. After finger procedures, some people developed tears in the skin (lacerations), and local skin and soft-tissue necrosis (death of skin cells). Some lacerations and necrosis required skin grafting, or other surgery including amputation. Call your healthcare provider right away if you get numbness, tingling, increased pain, or tears in the skin (laceration) in your treated finger or hand after your injection or after your follow-up visit
  • Hypersensitivity reactions, including anaphylaxis. Severe allergic reactions can happen in people who receive XIAFLEX because it contains foreign proteins. Call your healthcare provider right away if you have any of these symptoms of an allergic reaction after an injection of XIAFLEX:
    • hives
    • swollen face
    • breathing trouble
    • chest pain
    • low blood pressure
    • dizziness or fainting
  • Fainting. Fainting (passing out) or near fainting can happen in people who receive XIAFLEX, especially following finger procedures
    If you have dizziness or feel faint after receiving XIAFLEX, lie down until the symptoms go away.
  • Increased chance of bleeding. Bleeding or bruising at the injection site can happen in people who receive XIAFLEX. Talk to your healthcare provider if you have a problem with your blood clotting. XIAFLEX may not be right for you.

Before receiving XIAFLEX, tell your healthcare provider if you have had an allergic reaction to a previous XIAFLEX injection, or have a bleeding problem or any other medical conditions. Tell your healthcare provider about all the medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements. Using XIAFLEX with certain other medicines can cause serious side effects. Especially tell your healthcare provider if you take medicines to thin your blood (anticoagulants). If you are told to stop taking a blood thinner before your XIAFLEX injection, your healthcare provider should tell you when to restart the blood thinner. Ask your healthcare provider or pharmacist for a list of these medicines if you are unsure.

The most common side effects with XIAFLEX for the treatment of Dupuytren's contracture include:

  • swelling of the injection site or the hand
  • bruising or bleeding at the injection site
  • pain or tenderness of the injection site or the hand
  • swelling of the lymph nodes (glands) in the elbow or armpit
  • itching
  • breaks in the skin
  • redness or warmth of the skin
  • pain in the armpit

Tell your healthcare provider if you have any side effect that bothers you or does not go away. These are not all of the possible side effects with XIAFLEX. For more information, ask your healthcare provider or pharmacist.

Rx Only

Click for full Prescribing Information, including Medication Guide.

About Endo
Endo is a diversified specialty pharmaceutical company boldly transforming insights into life-enhancing therapies. Our passionate team members collaborate to develop and deliver these essential medicines. Together, we are committed to helping everyone we serve live their best life. Learn more at www.endo.com or connect with us on LinkedIn.

Cautionary Note Regarding Forward-Looking Statements
This press release contains forward-looking statements including, but not limited to, the statements by Mr. Elway and Ms. Wenstrup, and any statements relating to product efficacy, treatments or indications, therapeutic outcomes or treatment responses, safety or adverse reactions, and any statements that refer to expected, estimated or anticipated future results or that do not relate solely to historical facts. Statements including words such as "believes," "expects," "anticipates," "intends," "estimates," "plan," "will," "may," "look forward," "intends," "guidance," "future," "potential" or similar expressions are forward-looking statements. Because these statements reflect our current views, expectations and beliefs concerning future events, they involve risks and uncertainties, some of which we may not currently be able to predict. Although we believe that these forward-looking statements and other information are based upon reasonable assumptions and expectations, readers should not place undue reliance on these or any other forward-looking statements and information. Actual results may differ materially and adversely from current expectations based on a number of factors, including, among other things, changes in legislation or regulations, our ability to obtain and maintain adequate protection for our intellectual property rights, the impacts of competition such as those related to XIAFLEX, unfavorable safety or efficacy data, compliance with regulatory obligations, uncertainties and timing of the regulatory approval process, unexpected claims, litigation or other disputes, our ability to successfully implement and execute on our strategies and initiatives, and changes in competitive, market or regulatory conditions. Endo assumes no obligation to publicly update any forward-looking statements, whether as a result of new information, future developments or otherwise, except as may be required under applicable securities laws. Additional information concerning risk factors, including those referenced above, can be found in Endo's press releases and in its public filings with the U.S. Securities and Exchange Commission, including the discussion under the heading "Risk Factors" in Endo's most recent Form 10-Q and in Endo's final prospectus filed pursuant to Rule 424(b) under the Securities Act of 1933, as amended, in connection with Endo's Form S-1/A.

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SOURCE Endo, Inc.

FAQ

What treatment did John Elway receive for Dupuytren's contracture from Endo (NDOI)?

John Elway received XIAFLEX® (collagenase clostridium histolyticum) treatment for Dupuytren's contracture five years ago.

When will John Elway share his XIAFLEX treatment update for Endo (NDOI)?

John Elway will speak to media outlets on November 20, 2024, to share his patient journey and provide an update on his hand health.

When did John Elway first partner with Endo (NDOI) for Dupuytren's contracture awareness?

John Elway initially partnered with Endo in 2019 for a disease education campaign about Dupuytren's contracture.

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