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NuCana to Participate in Two Upcoming Investor Conferences

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NuCana plc (Nasdaq: NCNA) announces participation in two virtual investor conferences. The first is Cowen’s 42nd Annual Healthcare Conference from March 7-9, 2022. The second event is Oppenheimer's 32nd Annual Healthcare Conference on March 16, 2022, at 8:00 AM ET, which will be webcasted live. NuCana focuses on improving cancer treatment through its ProTide technology, with three ProTides in clinical development: Acelarin, NUC-3373, and NUC-7738. Acelarin is in Phase 3 for advanced biliary tract cancer, while NUC-3373 and NUC-7738 are in earlier studies for colorectal and solid tumors.

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EDINBURGH, United Kingdom, Feb. 28, 2022 (GLOBE NEWSWIRE) -- NuCana plc (Nasdaq: NCNA) announced today that Hugh Griffith, Chief Executive Officer, and Don Munoz, Chief Financial Officer, will participate in two upcoming virtual investor conferences.

Event: Cowen’s 42nd Annual Healthcare Conference
Dates: March 7-9, 2022

Event: Oppenheimer's 32nd Annual Healthcare Conference
Presentation Date: Wednesday, March 16, 2022
Presentation Time: 8:00 AM ET

The presentation at Oppenheimer's 32nd Annual Healthcare Conference will be webcast live and available for replay under “Events & Presentations” in the Investors section of the Company's website at www.nucana.com.

About NuCana
NuCana is a clinical-stage biopharmaceutical company focused on significantly improving treatment outcomes for patients with cancer by applying our ProTide technology to transform some of the most widely prescribed chemotherapy agents, nucleoside analogs, into more effective and safer medicines. While these conventional agents remain part of the standard of care for the treatment of many solid and hematological tumors, their efficacy is limited by cancer cell resistance mechanisms and they are often poorly tolerated. Utilizing our proprietary technology, we are developing new medicines, ProTides, designed to overcome key cancer resistance mechanisms and generate much higher concentrations of anti-cancer metabolites in cancer cells. NuCana’s robust pipeline includes three ProTides in clinical development. Acelarin and NUC-3373, are new chemical entities derived from the nucleoside analogs gemcitabine and 5-fluorouracil, respectively, two widely used chemotherapy agents. Acelarin is in a Phase 3 study for patients with advanced biliary tract cancer. NUC-3373 is in a Phase 1b/2 study in patients with metastatic colorectal cancer. Our third ProTide, NUC-7738, is a transformation of a novel anti-cancer nucleoside analog (3’-deoxyadenosine) and is in a Phase 1/2 study for patients with advanced solid tumors.

Forward-Looking Statements
This press release may contain “forward-looking” statements within the meaning of the Private Securities Litigation Reform Act of 1995 that are based on the beliefs and assumptions and on information currently available to management of NuCana plc (the “Company”). All statements other than statements of historical fact contained in this press release are forward-looking statements, including statements concerning the Company’s planned and ongoing clinical studies for the Company’s product candidates and the potential advantages of those product candidates, including Acelarin, NUC-3373 and NUC-7738; the initiation, enrollment, timing, progress, release of data from and results of those planned and ongoing clinical studies; the Company’s ability to submit an NDA for Acelarin under the FDA’s accelerated approval program, or at all; the Company’s goals with respect to the development, regulatory pathway and potential use, if approved, of each of its product candidates; and the utility of prior non-clinical and clinical data in determining future clinical results. In some cases, you can identify forward-looking statements by terminology such as “may,” “will,” “should,” “expects,” “plans,” “anticipates,” “believes,” “estimates,” “predicts,” “potential” or “continue” or the negative of these terms or other comparable terminology. Forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause the Company’s actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. These risks and uncertainties include, but are not limited to, the risks and uncertainties set forth in the “Risk Factors” section of the Company’s Annual Report on Form 20-F for the year ended December 31, 2020 filed with the Securities and Exchange Commission (“SEC”) on March 4, 2021, and subsequent reports that the Company files with the SEC. Forward-looking statements represent the Company’s beliefs and assumptions only as of the date of this press release. Although the Company believes that the expectations reflected in the forward-looking statements are reasonable, it cannot guarantee future results, levels of activity, performance or achievements. Except as required by law, the Company assumes no obligation to publicly update any forward-looking statements for any reason after the date of this press release to conform any of the forward-looking statements to actual results or to changes in its expectations.

For more information, please contact:

NuCana plc
Hugh S. Griffith
Chief Executive Officer
+44 131 357 1111
info@nucana.com

Westwicke, an ICR Company
Chris Brinzey
+1 339-970-2843
chris.brinzey@westwicke.com

RooneyPartners
Marion Janic
+1 212-223-4017
mjanic@rooneyco.com


FAQ

What is the purpose of NuCana's upcoming investor conferences?

NuCana will discuss its progress and future plans for its cancer treatments at Cowen’s and Oppenheimer's investor conferences.

When is Oppenheimer's 32nd Annual Healthcare Conference featuring NuCana?

Oppenheimer's 32nd Annual Healthcare Conference will take place on March 16, 2022, at 8:00 AM ET.

How can I access NuCana's presentation at the Oppenheimer conference?

NuCana's presentation can be accessed via a live webcast on their website under the 'Events & Presentations' section.

What are the main focuses of NuCana's clinical pipeline?

NuCana's pipeline focuses on developing ProTides to enhance the effectiveness and safety of conventional chemotherapy for various cancers.

What clinical trials are currently underway for NuCana's ProTides?

Acelarin is in a Phase 3 study for advanced biliary tract cancer, while NUC-3373 and NUC-7738 are in earlier stages for colorectal and solid tumors.

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