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Nanobiotix S.A. (Euronext: NANO / ISIN: FR0011341205) is a leading clinical-stage nanomedicine company specializing in the development of groundbreaking approaches for cancer treatment. The company's core technology, NanoXray, augments the effectiveness of radiotherapy, offering a more efficient treatment option for cancer patients. The innovative NanoXray products are designed to be compatible with existing radiotherapy treatments and aim to treat a broad spectrum of solid tumors, such as soft tissue sarcoma, head and neck cancers, liver cancers, prostate cancer, breast cancer, and glioblastoma.
The primary product candidate, NBTXR3, is currently undergoing evaluation for its efficacy in treating soft tissue sarcoma, head and neck cancers, prostate cancer, and liver cancers (both primary and metastases). Additionally, Nanobiotix has partnered with PharmaEngine in Taiwan to conduct trials for head and neck cancer and rectal cancer in the Asia Pacific region.
Nanobiotix has also embarked on a preclinical research program in immuno-oncology, further expanding its portfolio and potential for transformative cancer therapies. NBTXR3 works by magnifying the effects of radiotherapy within tumor cells, thereby enhancing cancer treatment without increasing the dose to surrounding healthy tissues.
Recently, Nanobiotix has been focused on validating the safety and efficacy of RT-activated NBTXR3 by moving to global registration for LA-HNSCC, accounting for the majority of its operational and financial resources. The company plans to provide an updated global development plan for NBTXR3 after further alignment with the Joint Steering Committee (JSC).
In terms of financial performance, Nanobiotix has laid out a cautious strategy, ensuring that it remains well-funded to support ongoing and future operations. Their forward-looking statements highlight the potential risks and uncertainties that could affect their business and financial performance.
For the latest updates, Nanobiotix has scheduled a conference call and webcast on May 22, 2024, at 8:00 am EDT / 2:00 pm CEST. It continues to engage the market, providing transparency to shareholders through various media and regular updates on their progress and milestones.
To keep up with the latest news, visit www.nanobiotix.com.
Nanobiotix has reported its voting rights and share count as of November 30, 2021. The company has 34,825,872 shares outstanding, with a total of 36,003,389 voting rights (gross) and 35,985,166 voting rights (net). This information aligns with regulatory requirements set by the French Financial Markets Authority.
Nanobiotix, listed on both Euronext Paris and Nasdaq, specializes in innovative therapeutic approaches in biotechnology, focusing on oncology and has market authorization for its lead candidate, NBTXR3.
NANOBIOTIX (NASDAQ: NBTX), a late-stage biotechnology company focusing on innovative cancer treatments, announced participation by CEO Laurent Levy in a virtual fireside chat at the Evercore ISI HealthCONx Conference on December 2, 2021, at 1:00 PM EST. The live audio webcast will be accessible on the company’s website, with an archived recording available for 90 days. NANOBIOTIX, founded in 2003 and headquartered in Paris, is known for its physics-based therapeutic approaches and has market authorization for its product NBTXR3 in Europe.
NBTXR3, developed by Nanobiotix, shows promising preclinical results presented at the 36th Annual Meeting of the Society for the Immunotherapy of Cancer (SITC). The data indicate that radiotherapy-activated NBTXR3 enhances CD8+ T cell infiltration and modulates the T cell receptor repertoire, suggesting improved immune priming. Additionally, the combination of NBTXR3 with anti-PD-1, anti-LAG3, and anti-TIGIT substantially elevated anti-tumor immune response activities. These findings underscore potential advancements in combination therapies for solid tumors.
Nanobiotix announced its latest regulatory update as of October 31, 2021, reporting a total of 34,825,872 shares outstanding. The gross total number of voting rights is 36,003,389, while the net total is 35,983,625. This update is in compliance with the French Commercial Code and aims to ensure transparency in shareholder communications. Established in 2003, the company focuses on innovative therapeutic solutions in oncology, with its lead candidate NBTXR3 already authorized in Europe for treating soft tissue sarcoma.
Nanobiotix, a late-stage biotechnology company specializing in innovative cancer treatments, announced CEO Laurent Levy's participation in a fireside chat at the Jefferies London Healthcare Conference. Scheduled for November 16, 2021, at 3:40 PM GMT/10:40 AM EST, the event will be live-streamed on the company's website. Established in 2003, Nanobiotix focuses on physics-based therapies and holds over 30 patents. Its lead product, NBTXR3, is authorized in Europe for soft tissue sarcoma under the brand name Hensify®.
Nanobiotix has released first survival data from its NBTXR3 program at the ASTRO 2021 Annual Meeting. In a group of 41 elderly patients with locally advanced head and neck squamous cell carcinoma (LA-HNSCC), the median overall survival (mOS) was 18.1 months and median progression-free survival (mPFS) was 10.6 months. The best objective response rate (ORR) was 85.4%, with a complete response rate (CRR) of 63.4%. These positive findings support future phase III trials aimed at this challenging patient group.
Nanobiotix (NASDAQ: NBTX) reported progress in its oncology clinical programs, highlighting published preclinical data in the
Nanobiotix announces its total number of shares and voting rights as of September 30, 2021. The company had 34,825,872 outstanding shares with 35,999,889 total voting rights gross and 35,986,273 total voting rights net. This report complies with the French Commercial Code and the General Regulations of the Autorité des Marchés Financiers. As a clinical biotechnology company, Nanobiotix focuses on innovative therapeutic approaches in oncology with its lead candidate NBTXR3 already authorized in Europe for treating soft tissue sarcoma under the brand name Hensify®.
NANOBIOTIX (NASDAQ: NBTX) announced five presentations at the ASTRO 2021 Annual Meeting, from October 24-27. Key highlights include:
- Poster presentation by Pr. Christophe Le Tourneau on phase I data for NBTXR3 in head and neck cancer.
- Oral presentation by Dr. Tanguy Y. Seiwert discussing NBTXR3's potential effects as a single agent and with anti-PD-1.
- Dr. Sylvie Bonvalot's follow-up on phase II/III STS study.
NBTXR3, a novel oncology product, is designed for use with radiotherapy, showing promise in treating solid tumors.
Nanobiotix (NASDAQ: NBTX) announced the publication of preclinical data in the International Journal of Radiation Oncology, showcasing the potential of NBTXR3 combined with radiotherapy and anti-PD-1 to enhance tumor treatment. The study reveals that NBTXR3 effectively controls tumor growth in both sensitive and resistant models, improves immune response, and reduces metastasis. This research supports NBTXR3's exploration as a novel treatment option for metastatic lung cancer, aiming to convert irradiated tumors into 'self-vaccines' for broader therapeutic use.
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