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Myriad Genetics to Present New Data at San Antonio Breast Cancer Symposium

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Myriad Genetics (NASDAQ: MYGN) announced new data presentations at the 2024 San Antonio Breast Cancer Symposium (SABCS). The presentations include validation data for their high-definition tumor-informed MRD assay for breast cancer and the MyRisk® with RiskScore® Breast Cancer Risk Assessment Tool.

Key presentations include a spotlight session on a polygenic breast cancer risk assessment tool, data on polygenic-based breast cancer risk prediction's impact on patient management, and analytical validation of their MRD assay. Dr. Holly Pederson will present findings on polygenic risk scores in Hispanic women.

The company will showcase several products at booth #1327, including the MyRisk® Hereditary Cancer Test, Precise Tumor® Molecular Profile Test, MyChoice® CDx, and EndoPredict® Breast Cancer Prognostic Test.

Myriad Genetics (NASDAQ: MYGN) ha annunciato nuove presentazioni di dati al 2024 San Antonio Breast Cancer Symposium (SABCS). Le presentazioni includono dati di validazione per il loro test MRD informato dal tumore ad alta definizione per il cancro al seno e lo strumento di valutazione del rischio di cancro al seno MyRisk® con RiskScore®.

Le presentazioni chiave includono una sessione di approfondimento su uno strumento di valutazione del rischio di cancro al seno poligenico, dati sull'impatto della previsione del rischio di cancro al seno basata su polimorfismi sulla gestione dei pazienti e la validazione analitica del loro test MRD. La Dott.ssa Holly Pederson presenterà i risultati sui punteggi di rischio poligenico nelle donne ispaniche.

La società mostrerà diversi prodotti presso lo stand #1327, tra cui il MyRisk® Hereditary Cancer Test, il Precise Tumor® Molecular Profile Test, il MyChoice® CDx e il EndoPredict® Breast Cancer Prognostic Test.

Myriad Genetics (NASDAQ: MYGN) anunció nuevas presentaciones de datos en el 2024 San Antonio Breast Cancer Symposium (SABCS). Las presentaciones incluyen datos de validación para su ensayo MRD informado por tumor de alta definición para el cáncer de mama y la herramienta de evaluación de riesgo de cáncer de mama MyRisk® con RiskScore®.

Las presentaciones clave incluyen una sesión destacada sobre una herramienta de evaluación del riesgo de cáncer de mama poligénico, datos sobre el impacto de la predicción del riesgo de cáncer de mama basada en polimorfismos en la gestión de pacientes, y la validación analítica de su ensayo MRD. La Dra. Holly Pederson presentará hallazgos sobre los puntajes de riesgo poligénico en mujeres hispanas.

La empresa exhibirá varios productos en el stand #1327, incluyendo el MyRisk® Hereditary Cancer Test, el Precise Tumor® Molecular Profile Test, el MyChoice® CDx y el EndoPredict® Breast Cancer Prognostic Test.

Myriad Genetics (NASDAQ: MYGN)2024 San Antonio Breast Cancer Symposium (SABCS)에서 새로운 데이터 발표를 알렸습니다. 발표 내용에는 유방암을 위한 고해상도 종양 기반 MRD 검사에 대한 검증 데이터와 MyRisk® RiskScore® 유방암 위험 평가 도구가 포함됩니다.

주요 발표 내용에는 다유전자 유방암 위험 평가 도구에 대한 심층 세션, 다유전자 기반 유방암 위험 예측이 환자 관리에 미치는 영향에 대한 데이터, 그리고 MRD 검사에 대한 분석적 검증이 포함됩니다. 홀리 피더슨 박사가 히스패닉 여성의 다유전자 위험 점수에 대한 결과를 발표할 예정입니다.

회사는 부스 #1327에서 MyRisk® 유전적 암 검사, Precise Tumor® 분자 프로파일 검사, MyChoice® CDx, EndoPredict® 유방암 예후 검사 등 여러 제품을 선보일 예정입니다.

Myriad Genetics (NASDAQ: MYGN) a annoncé de nouvelles présentations de données lors du 2024 San Antonio Breast Cancer Symposium (SABCS). Les présentations comprennent des données de validation pour leur test MRD informé par le cancer du sein et l'outil d'évaluation des risques de cancer du sein MyRisk® avec RiskScore®.

Les présentations clés comprennent une session phare sur un outil d'évaluation du risque de cancer du sein polygénique, des données sur l'impact de la prédiction du risque de cancer du sein basé sur des polymorphismes sur la gestion des patients, et la validation analytique de leur test MRD. Dr. Holly Pederson présentera des résultats sur les scores de risque polygénique chez les femmes hispaniques.

L'entreprise présentera plusieurs produits au stand #1327, y compris le MyRisk® Hereditary Cancer Test, le Precise Tumor® Molecular Profile Test, le MyChoice® CDx, et le EndoPredict® Breast Cancer Prognostic Test.

Myriad Genetics (NASDAQ: MYGN) hat neue Datenpräsentationen beim 2024 San Antonio Breast Cancer Symposium (SABCS) angekündigt. Die Präsentationen umfassen Validierungsdaten für ihren hochauflösenden tumorinformierten MRD-Test für Brustkrebs sowie das MyRisk® mit dem RiskScore® Brustkrebs-Risikoassessor.

Zu den wesentlichen Präsentationen gehört eine Spotlight-Session zu einem polygenetischen Brustkrebs-Risikoassessment-Tool, Daten über die Auswirkungen der polygenetischen Risikoabschätzung auf das Patientenmanagement und die analytische Validierung ihres MRD-Tests. Dr. Holly Pederson wird Ergebnisse zu polygenen Risiko-Scores bei hispanischen Frauen präsentieren.

Das Unternehmen wird mehrere Produkte am Stand #1327 präsentieren, darunter den MyRisk® Hereditary Cancer Test, den Precise Tumor® Molecular Profile Test, den MyChoice® CDx und den EndoPredict® Breast Cancer Prognostic Test.

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Presentations include analytical validation of Myriad’s high-definition tumor informed MRD assay for breast cancer and its Breast Cancer Risk Assessment Tool MyRisk® with RiskScore®

SALT LAKE CITY, Dec. 09, 2024 (GLOBE NEWSWIRE) -- Myriad Genetics, Inc. (NASDAQ: MYGN), a leader in genetic testing and precision medicine, announced it will present new data at the 2024 San Antonio Breast Cancer Symposium® (SABCS), including a spotlight presentation on a breast cancer risk assessment tool that combines a polygenic score for all ancestries.

Additional new data will show how Myriad’s second-generation tumor-informed molecular residual disease (MRD) assay demonstrated high sensitivity, specificity and measurement accuracy, which, together, will facilitate improved resolution in residual-disease detection and extend lead times in recurrence detection.

“We are very excited to share validation data of our MRD assay. SABCS gives us the opportunity to showcase our clinical expertise in the prevention and treatment of early and advanced breast cancer,” said George Daneker, MD, President and Chief Clinical Officer, Oncology, Myriad Genetics. “Myriad is one of the only labs that can offer germline and tumor genomic testing, combined with customizable workflow solutions and point-of-care patient education sessions. Our test results are supported by treatment-focused reporting, concordance checks between germline and tumor genomic results, and a summary sheet designed to help oncologists and breast surgeons interpret actionable insights more effectively.”

Myriad Genetics Data Presentations

Spotlight Presentation: Session 16, PS16-01: Polygenic Risk
Date: Thursday, Dec. 12, 2024, 5:30-7:00 pm (CST), Hemisfair Ballroom 3
Presenter: Timothy Simmons, PhD, Biostatistician III, Myriad Genetics
The presentation will share longitudinal validation in the UK Biobank of a breast cancer risk assessment tool that combines a polygenic score for all ancestries with traditional risk factors.

Rapid-Fire Presentation: RF1-06
Date: Wednesday, Dec. 11, 2024, 12:00-12:50 pm (CST), Hall 1
Presenter: Katie Johansen Taber, PhD, Vice President, Clinical Product Research & Partnerships, Myriad Genetics
Dr. Johansen Taber will share data detailing the association of polygenic-based breast cancer risk prediction with patient management.

Poster Presentation: P2-04-23
Date: Wednesday, Dec. 11, 2024, 5:30-7:00 pm (CST), Halls 2-3
Presenter: Ashley Acevedo, PhD, Staff Computational Scientist, Myriad Genetics
This poster shares the analytical validation of a high-definition tumor-informed Molecular Residual Disease (MRD) assay to demonstrate robust detection at low-tumor fractions, which are common in breast cancer.

Poster Presentation: P3-02-10
Date: Thursday, Dec. 12, 2024, 12:30-2:00 pm (CST), Halls 2-3
Presenter: Holly Pederson, MD, Cleveland Clinic
Dr. Pederson will share her evaluation of a polygenic risk score as a predictor of breast cancer, triple-negative breast cancer, and early-onset disease in Hispanic women.

In addition to data presentations, Myriad will welcome attendees to its booth (#1327) during exhibition hours. Among the Myriad products highlighted in the company’s SABCS exhibit are:

  • MyRisk® Hereditary Cancer Test evaluates 48 genes to help healthcare providers identify their patients’ risk of developing 11 different types of hereditary cancer. MyRisk’s clear, actionable results are the foundation for personalized care plans to help patients make confident, informed decisions about medical management. MyRisk with RiskScore® provides unaffected patients with a comprehensive, personalized assessment of the five-year risk and remaining lifetime risk of developing breast cancer.
  • Precise Tumor® Molecular Profile Test is a pan-cancer solid tumor comprehensive genomic profiling test that helps clinicians with straightforward interpretations, prioritization of therapies, and the next steps specific to each patient’s genomic result.
  • MyChoice® CDx is one of the most comprehensive homologous recombination deficiency (HRD) tests available, enabling physicians to identify patients with tumors that have lost the ability to repair double-stranded DNA breaks, resulting in increased susceptibility to DNA-damaging drugs such as platinum drugs or PARP inhibitors. The MyChoice test comprises tumor sequencing of the BRCA1 and BRCA2 genes and a composite of three proprietary technologies (loss of heterozygosity, telomeric allelic imbalance and large-scale state transitions).
  • EndoPredict® Breast Cancer Prognostic Test is for patients with ER+, HER2-, node negative or node positive breast cancer. The test provides three individualized results used to help determine the most appropriate breast cancer treatment.

About Myriad Genetics
Myriad Genetics is a leading genetic testing and precision medicine company dedicated to advancing health and well-being for all. Myriad develops and offers genetic tests that help assess the risk of developing disease or disease progression and guide treatment decisions across medical specialties where genetic insights can significantly improve patient care and lower healthcare costs. For more information, visit www.myriad.com.

Safe Harbor Statement
This press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, including that the company will present new data at SABCS and that the company’s new data that will be shared at SABCS will show how the company’s second-generation tumor-informed MRD assay demonstrated high sensitivity, specificity and measurement accuracy, which, together, will facilitate improved resolution in residual-disease detection and extend lead times in recurrence detection. These “forward-looking statements” are management’s expectations of future events as of the date hereof and are subject to known and unknown risks and uncertainties that could cause actual results, conditions, and events to differ materially and adversely from those anticipated. Such factors include those risks described in the company’s filings with the U.S. Securities and Exchange Commission, including the company’s Annual Report on Form 10-K filed on February 28, 2024, as well as any updates to those risk factors filed from time to time in the company’s Quarterly Reports on Form 10-Q or Current Reports on Form 8-K. Myriad is not under any obligation, and it expressly disclaims any obligation, to update or alter any forward-looking statements, whether as a result of new information, future events or otherwise except as required by law.

Investor Contact
Matt Scalo
(801) 584-3532
IR@myriad.com

Media Contact
Glenn Farrell
(385) 318-3718
PR@myriad.com


FAQ

What new data is Myriad Genetics presenting at SABCS 2024?

Myriad Genetics is presenting validation data for their tumor-informed MRD assay and MyRisk with RiskScore assessment tool, including a spotlight presentation on polygenic breast cancer risk assessment and studies on risk prediction in patient management.

When and where are Myriad Genetics (MYGN) presentations at SABCS 2024?

The presentations are scheduled for December 11-12, 2024, with sessions in Hemisfair Ballroom 3, Hall 1, and Halls 2-3 at the San Antonio Breast Cancer Symposium.

What products will Myriad Genetics (MYGN) showcase at SABCS 2024?

Myriad will showcase MyRisk Hereditary Cancer Test, Precise Tumor Molecular Profile Test, MyChoice CDx, and EndoPredict Breast Cancer Prognostic Test at booth #1327.

What is the focus of Dr. Holly Pederson's SABCS 2024 presentation for Myriad Genetics (MYGN)?

Dr. Pederson will present an evaluation of polygenic risk scores as predictors of breast cancer, triple-negative breast cancer, and early-onset disease in Hispanic women.

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