Myriad Genetics Announces Two New Patents Granted for its Molecular Residual Disease (MRD) Assay
Myriad Genetics (NASDAQ: MYGN) has been granted two new patents by the United States Patent and Trademark Office for its molecular residual disease (MRD) assay technology. The first patent (No. 12,215,391) covers proprietary automated methods of MRD analysis, specifically focusing on automation systems interfacing with laboratory equipment. The second patent (No. 12,215,392) relates to patient journey aspects of MRD, covering methods performed before, during, or after treatment, or during remission.
These patents follow three earlier patents awarded in 2024 for foundational platform MRD technology and cell-free DNA preparation methods. The company's Precise® MRD test is designed to determine treatment effectiveness and cancer recurrence. The test is currently under evaluation in several studies and has completed transition to Myriad's Salt Lake City laboratory facility.
Myriad Genetics (NASDAQ: MYGN) ha ricevuto due nuovi brevetti dall'Ufficio brevetti e marchi degli Stati Uniti per la sua tecnologia di analisi della malattia residua molecolare (MRD). Il primo brevetto (No. 12,215,391) riguarda metodi automatizzati proprietari di analisi MRD, focalizzandosi specificamente sui sistemi di automazione che si interfacciano con le attrezzature di laboratorio. Il secondo brevetto (No. 12,215,392) concerne gli aspetti del percorso del paziente della MRD, coprendo metodi eseguiti prima, durante o dopo il trattamento, o durante la remissione.
Questi brevetti seguono tre brevetti precedentemente concessi nel 2024 per la tecnologia piattaforma di base della MRD e i metodi di preparazione del DNA libero. Il test Precise® MRD dell'azienda è progettato per determinare l'efficacia del trattamento e la ricorrenza del cancro. Attualmente, il test è in fase di valutazione in diversi studi e ha completato la transizione presso il laboratorio dell'azienda a Salt Lake City.
Myriad Genetics (NASDAQ: MYGN) ha recibido dos nuevas patentes de la Oficina de Patentes y Marcas de Estados Unidos para su tecnología de ensayo de enfermedad residual molecular (MRD). La primera patente (No. 12,215,391) cubre métodos automatizados propietarios de análisis de MRD, centrándose específicamente en sistemas de automatización que interactúan con equipos de laboratorio. La segunda patente (No. 12,215,392) se relaciona con los aspectos del recorrido del paciente de la MRD, cubriendo métodos realizados antes, durante o después del tratamiento, o durante la remisión.
Estas patentes siguen a tres patentes anteriores otorgadas en 2024 para la tecnología de plataforma fundamental de MRD y métodos de preparación de ADN libre. La prueba Precise® MRD de la empresa está diseñada para determinar la efectividad del tratamiento y la recurrencia del cáncer. La prueba se está evaluando actualmente en varios estudios y ha completado la transición a las instalaciones de laboratorio de Myriad en Salt Lake City.
Myriad Genetics (NASDAQ: MYGN)는 미국 특허청으로부터 분자 잔여 질병(MRD) 분석 기술에 대한 두 개의 새로운 특허를 부여받았습니다. 첫 번째 특허(번호 12,215,391)는 자동화 시스템이 실험실 장비와 인터페이스되는 것에 특히 중점을 두고 MRD 분석의 독점적인 자동화 방법을 다룹니다. 두 번째 특허(번호 12,215,392)는 MRD 환자 여정의 측면과 관련이 있으며, 치료 전, 중, 후 또는 완화 기간 동안 수행되는 방법을 포함합니다.
이 특허는 2024년에 기초 플랫폼 MRD 기술과 자유 DNA 준비 방법에 대해 부여된 세 개의 이전 특허에 이어지는 것입니다. 회사의 Precise® MRD 테스트는 치료 효과와 암 재발을 결정하기 위해 설계되었습니다. 현재 이 테스트는 여러 연구에서 평가 중이며, Myriad의 솔트레이크시티 실험실 시설로의 전환을 완료했습니다.
Myriad Genetics (NASDAQ: MYGN) a reçu deux nouveaux brevets de l'Office des brevets et des marques des États-Unis pour sa technologie d'analyse de la maladie résiduelle moléculaire (MRD). Le premier brevet (n° 12,215,391) concerne des méthodes automatisées propriétaires d'analyse de la MRD, se concentrant spécifiquement sur les systèmes d'automatisation interfacés avec les équipements de laboratoire. Le deuxième brevet (n° 12,215,392) se rapporte aux aspects du parcours des patients de la MRD, englobant les méthodes réalisées avant, pendant ou après le traitement, ou pendant la rémission.
Ces brevets suivent trois brevets précédemment accordés en 2024 pour la technologie de plateforme fondamentale de la MRD et les méthodes de préparation de l'ADN libre. Le test Precise® MRD de l'entreprise est conçu pour déterminer l'efficacité du traitement et la récurrence du cancer. Le test est actuellement évalué dans plusieurs études et a achevé sa transition vers le laboratoire de Myriad à Salt Lake City.
Myriad Genetics (NASDAQ: MYGN) hat vom US-Patent-und- Markenamt zwei neue Patente für seine Technologie zur Analyse von molekularen Residualerkrankungen (MRD) erhalten. Das erste Patent (Nr. 12,215,391) betrifft proprietäre automatisierte Methoden zur MRD-Analyse, wobei der Fokus speziell auf Automatisierungssystemen liegt, die mit Laborgeräten Schnittstellen bilden. Das zweite Patent (Nr. 12,215,392) bezieht sich auf Aspekte des Patientenverlaufs bei MRD und umfasst Methoden, die vor, während oder nach der Behandlung oder während der Remission durchgeführt werden.
Diese Patente folgen auf drei frühere Patente, die 2024 für grundlegende Plattformtechnologien von MRD und Methoden zur Aufbereitung von zellfreier DNA vergeben wurden. Der Precise® MRD-Test des Unternehmens ist darauf ausgelegt, die Wirksamkeit der Behandlung und das Wiederauftreten von Krebs zu bestimmen. Der Test wird derzeit in mehreren Studien evaluiert und hat den Übergang zu Myriads Labor in Salt Lake City abgeschlossen.
- Secured two new strategic patents strengthening MRD testing intellectual property portfolio
- Previously obtained three related patents in 2024, building comprehensive IP protection
- Successfully completed laboratory facility transition for Precise MRD test in Salt Lake City
- Product still in evaluation phase, not yet generating revenue
Insights
The first patent (No. 12,215,391) covering automated MRD analysis methods is particularly valuable as it protects scalable, high-throughput testing capabilities - a critical factor for commercial success in the diagnostic market. Automation patents typically translate to improved operational efficiency and reduced costs, potentially leading to higher profit margins.
The second patent (No. 12,215,392) focusing on patient journey aspects creates a comprehensive protective moat around various testing timepoints - before, during and after treatment, as well as during remission. This broad coverage effectively positions Myriad to capture multiple testing opportunities throughout a patient's cancer journey, potentially leading to recurring revenue streams.
Combined with their three existing MRD-related patents from 2024, Myriad has built a robust five-patent portfolio specifically around their Precise® MRD test. This intellectual property strategy appears designed to create high barriers to entry for competitors while protecting various aspects of their technology - from foundational platform technology to specific implementation methods.
The market impact is particularly noteworthy as the global MRD testing market is projected to see substantial growth, driven by increasing cancer prevalence and the shift toward personalized medicine. By securing these patents, Myriad positions itself to potentially capture a larger share of this expanding market through both direct testing services and potential licensing opportunities.
The strategic significance of Myriad's MRD patent portfolio extends beyond mere intellectual property protection - it addresses critical unmet needs in cancer care. The ultrasensitive Precise MRD test's ability to monitor both treatment effectiveness and cancer recurrence positions it as a valuable tool in the precision oncology arsenal.
The technology's implementation in the new state-of-the-art laboratory facility in Salt Lake City suggests a commitment to maintaining high-quality standards and scalability. The ongoing evaluation in multiple high-impact studies indicates a robust clinical validation strategy, which is important for market adoption and potential insurance coverage.
The timing of these patents is particularly strategic as the oncology field increasingly emphasizes early detection and monitoring. The ability to detect molecular residual disease with high sensitivity could potentially lead to earlier intervention in cases of cancer recurrence, improving patient outcomes and reducing treatment costs.
For investors, the expansion of Myriad's oncology testing portfolio represents diversification beyond their traditional hereditary cancer testing business. The MRD testing market presents significant growth potential, particularly given the increasing adoption of precision medicine approaches in oncology and the growing need for more accurate treatment response monitoring.
SALT LAKE CITY, Feb. 05, 2025 (GLOBE NEWSWIRE) -- Myriad Genetics, Inc. (NASDAQ: MYGN), a leader in genetic and tumor genomic testing and precision medicine, announced that the United States Patent and Trademark Office has issued two new patents that further advance Myriad’s ability to bring its tumor-informed, high-definition, molecular residual disease (MRD) assay to market.
- US patent No. 12,215,391 relates to Myriad’s proprietary automated methods of MRD analysis. Specifically, the claims are relevant to certain MRD methods that are performed via an automation system configured to interface with laboratory equipment.
- US patent No. 12,215,392 relates to patient journey aspects of MRD. Specifically, the claims are relevant to certain MRD methods performed before, during or after treatment, or during remission.
In 2024, Myriad Genetics was awarded three patents related to foundational platform MRD technology and cell-free DNA preparation methods that each enable highly sensitive and specific tumor-informed, sequencing-based MRD assays, such as Myriad’s Precise® MRD test.
“These additional patents underscore Myriad’s novel proprietary technology that we believe will help advance Myriad’s position as a precision medicine leader. Our Precise MRD assay will work to answer the two fundamental questions that clinicians and patients have in the fight against cancer: 1) is treatment working? and 2) has cancer recurred?” said Paul J. Diaz, President and CEO, Myriad Genetics. “We believe our ultrasensitive Precise MRD test will enhance treatment strategies for providers and improve patient outcomes, as well as open new opportunities for therapy-response and recurrence monitoring.”
Myriad continues to develop its Precise MRD assay to meet the needs of patients with cancer, academic partners, and biopharma companies. The test is currently being evaluated in several high-impact studies and recently completed transitioning to the company’s state-of-the-art laboratory facility in Salt Lake City.
About Precise Molecular Residual Disease (MRD) Test
Myriad’s Precise MRD test is whole-genome sequencing (WGS)-based assay, enabling the custom selection of hundreds to thousands of targeted variants for deep analysis. Myriad’s MRD assay targets 1,000 sites specific to the tumor genome, enabling sensitive detection of very low tumor levels. Precise MRD is available for use in research studies pursued jointly by Myriad and academic or pharmaceutical investigators.
About Myriad Genetics
Myriad Genetics is a leading genetic and tumor genomic testing and precision medicine company dedicated to advancing health and well-being for all. Myriad Genetics develops and offers genetic tests that help assess the risk of developing disease or disease progression and guide treatment decisions across medical specialties where genetic insights can significantly improve patient care and lower healthcare costs. For more information, visit www.myriad.com.
Safe Harbor Statement
This press release contains “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995, including statements relating to the company’s belief that these additional patents underscore the company’s proprietary technology and will help advance its position as a precision medicine leader, the anticipate benefits of its Precise MRD assay in addressing fundamental questions in cancer care related to treatment efficacy and cancer recurrence, the potential for its ultrasensitive assay to enhance treatment strategies, improve patient outcomes, and create new opportunities for therapy-response and recurrence monitoring, and the company’s ongoing efforts to develop its Precise MRD assay to meet the needs of patients with cancer, academic partners, and biopharma companies. These “forward-looking statements” are management’s expectations of future events as of the date hereof and are subject to known and unknown risks and uncertainties that could cause actual results, conditions, and events to differ materially and adversely from those anticipated. Such factors include those risks described in the company’s filings with the U.S. Securities and Exchange Commission, including the company’s Annual Report on Form 10-K filed on February 28, 2024, as well as any updates to those risk factors filed from time to time in the company’s Quarterly Reports on Form 10-Q or Current Reports on Form 8-K. Myriad is not under any obligation, and it expressly disclaims any obligation, to update or alter any forward-looking statements, whether as a result of new information, future events or otherwise except as required by law.
Investor Contact
Matt Scalo
(801) 584-3532
IR@myriad.com
Media Contact
Kate Schraml
(224) 875-4493
PR@myriad.com
FAQ
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