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Milestone Pharmaceuticals Inc. (Symbol: MIST) is a biopharmaceutical company headquartered at 6100 Royalmount Ave, Montreal, QC, Canada. The company specializes in developing and commercializing innovative treatments for cardiovascular conditions, with a key focus on its lead investigational product, etripamil.
Milestone's primary product, etripamil, is a calcium channel blocker designed for rapid onset as a nasal spray. This unique formulation allows patients to self-administer the medication to terminate episodes of paroxysmal supraventricular tachycardia (PSVT). PSVT is a condition characterized by an abnormally fast heart rate, which can be both sudden and recurrent.
The company is also conducting a Phase 2 clinical trial to evaluate the efficacy of etripamil for patients with atrial fibrillation experiencing a rapid ventricular rate (AFib-RVR). This trial marks another significant step in expanding the usage of etripamil to address additional cardiovascular indications.
Recent Achievements and Current Projects:
- Milestone intends to use the proceeds from its latest offering to further the development of etripamil for PSVT and AFib-RVR, along with other general corporate purposes.
- The company has secured a shelf registration statement on Form S-3, effective as of February 2, 2022, allowing for streamlined securities offering.
- Milestone actively participates in educational initiatives, such as partnering with the Arrhythmia Alliance for SVT Awareness Day, aimed at raising awareness about heart rhythm disorders.
Financial Condition and Partnerships: Milestone maintains a strong financial position, supported by recent offerings and strategic partnerships. The company's collaborations with healthcare organizations and participation in global awareness campaigns underline its commitment to improving cardiovascular health.
Key Highlights:
- Innovative treatment for PSVT with a patient-administered nasal spray.
- Ongoing Phase 2 trial for AFib-RVR.
- Effective use of proceeds for development and expansion.
- Active involvement in cardiovascular health awareness initiatives.
With a robust pipeline and strategic initiatives, Milestone Pharmaceuticals Inc. is dedicated to addressing unmet needs in cardiovascular care, making significant strides in the biopharmaceutical industry.
Milestone Pharmaceuticals Inc. (Nasdaq: MIST) announced participation at the 22nd Annual Needham Virtual Healthcare Conference on April 19, 2023, at 3:45 p.m. ET. The live presentation will be available via webcast on the company's website.
Milestone focuses on innovative cardiovascular medicines, with its lead product candidate, etripamil, having recently completed a Phase 3 clinical program for treating paroxysmal supraventricular tachycardia (PSVT). It is also in a Phase 2 trial for atrial fibrillation with rapid ventricular rate (AFib-RVR). The company operates in both Canada and the United States.
Milestone Pharmaceuticals (MIST) reported its financial results for Q4 and FY 2022, highlighting significant corporate developments. Following a strategic financing of $125 million in March 2023, the company expects sufficient cash resources to fund operations into mid-2025. A New Drug Application (NDA) for etripamil, aimed at treating paroxysmal supraventricular tachycardia (PSVT), is expected to be submitted in Q3 2023. The Phase 3 RAPID trial showed positive topline results, with 64.3% of patients converting to sinus rhythm with etripamil compared to 31.2% on placebo. However, the company's operating loss increased to $58.4 million in FY 2022 from $42.9 million in FY 2021.
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