Mirum Pharmaceuticals Added to NASDAQ Biotechnology Index

Rhea-AI Summary

Mirum Pharmaceuticals, Inc. (NASDAQ: MIRM) has been added to the NASDAQ Biotechnology Index, effective December 20, 2021. This index includes NASDAQ-listed companies in the biotechnology and pharmaceutical sectors that meet specific eligibility criteria. Mirum is focused on treating rare liver diseases, with its approved drug LIVMARLI™ for cholestatic pruritus in Alagille syndrome patients. The company is also developing investigational treatments and has acquired options for gene therapies targeting PFIC types 2 and 3.

Positive

• Inclusion in the NASDAQ Biotechnology Index may enhance visibility and credibility for MIRM.
• Mirum's ongoing clinical trials and pipeline expansions indicate potential for future revenue growth.

Negative

• None.

FOSTER CITY, Calif.--(BUSINESS WIRE)-- Mirum Pharmaceuticals, Inc. (NASDAQ: MIRM) today announced that it has been selected for addition to the NASDAQ Biotechnology Index. The addition will become effective prior to market open on Monday, December 20, 2021.

The NASDAQ Biotechnology Index contains securities of NASDAQ-listed companies classified according to the Industry Classification Benchmark as either Biotechnology or Pharmaceuticals which also meet other eligibility criteria. The NASDAQ Biotechnology Index is re-ranked annually and all securities in the index are listed on the NASDAQ Global Market or the NASDAQ Global Select Market and meet minimum market value and share volume requirements among other criteria. The NASDAQ Biotechnology Index is calculated under a modified capitalization-weighted methodology. For more information, please visit the NASDAQ Biotechnology Index information page on the NASDAQ website.

About Mirum Pharmaceuticals, Inc.

Mirum Pharmaceuticals, Inc. is a biopharmaceutical company dedicated to transforming the treatment of rare liver diseases. Mirum’s approved medication is LIVMARLI™ (maralixibat) oral solution which is approved in the U.S. for the treatment of cholestatic pruritus in patients with Alagille syndrome one year of age and older.

Mirum’s late-stage pipeline includes two investigational treatments for debilitating liver diseases affecting children and adults. Maralixibat (LIVMARLI), an oral ileal bile acid transporter (IBAT) inhibitor, is currently being evaluated in clinical trials for pediatric liver diseases and includes the MARCH Phase 3 study for progressive familial intrahepatic cholestasis (PFIC) and the EMBARK Phase 2b study for patients with biliary atresia. In addition, Mirum has an expanded access program open in Canada, Australia, the UK and several countries in Europe for eligible patients with Alagille syndrome.

Mirum has submitted a Marketing Authorization Application to the European Medicines Agency for maralixibat for the treatment of cholestatic liver disease in patients with Alagille syndrome.

Mirum’s second investigational treatment, volixibat, also an oral IBAT inhibitor, is being evaluated in three potentially registrational studies including the OHANA Phase 2b study for pregnant women with intrahepatic cholestasis of pregnancy, VISTAS Phase 2b study for adults with primary sclerosing cholangitis, and the VANTAGE Phase 2b study for primary biliary cholangitis.

To augment its pipeline in cholestatic liver disease, Mirum has acquired the exclusive option to develop and commercialize gene therapy programs VTX-803 and VTX-802 for PFIC3 and PFIC2, respectively, from Vivet Therapeutics SAS, following preclinical evaluation and investigational new drug-enabling studies.

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View source version on businesswire.com: https://www.businesswire.com/news/home/20211215005387/en/

Media Contact:

Erin Murphy

media@mirumpharma.com

Investor Contacts:

Ian Clements, Ph.D.

ir@mirumpharma.com

Sam Martin

Argot Partners

ir@mirumpharma.com

Source: Mirum Pharmaceuticals, Inc.

FAQ

What is the significance of Mirum Pharmaceuticals' addition to the NASDAQ Biotechnology Index?

The addition to the NASDAQ Biotechnology Index enhances Mirum's visibility and credibility in the biotech sector, potentially attracting more investors.

When does Mirum Pharmaceuticals join the NASDAQ Biotechnology Index?

Mirum Pharmaceuticals will be added to the NASDAQ Biotechnology Index effective December 20, 2021.

What therapies is Mirum Pharmaceuticals currently developing?

Mirum Pharmaceuticals is developing LIVMARLI™ for cholestatic pruritus and several investigational treatments for liver diseases, including gene therapies for PFIC.

What is the approved medication by Mirum Pharmaceuticals?

Mirum's approved medication is LIVMARLI™ (maralixibat), which treats cholestatic pruritus in patients with Alagille syndrome.