MIMEDX Receives $4.6 Million Award from the Department of Defense to Advance the Treatment of Combat Casualty Wounds and Burns

Rhea-AI Summary

Mimedx Group, Inc. (MDXG) has secured a $4.6 million award to evaluate the PURION processed Dehydrated Human Amnion Chorion Membrane (DHACM) for treating combat wounds and burns. Sponsored by the Medical Technology Enterprise Consortium (MTEC) and the U.S. Army, the funding aims to improve outcomes for military personnel facing acute injuries. Clinical trials will be led by the University of Arizona and University of Miami, focusing on the safety and efficacy of DHACM. This initiative underscores a commitment to addressing critical medical needs in military settings.

Positive

• Award of $4.6 million to evaluate DHACM for military wound care.
• Collaboration with U.S. Army and reputable institutions like University of Arizona and University of Miami.
• Potential to enhance treatment outcomes for combat-related injuries.

Negative

• None.

Funding Enables Evaluation of PURION^® Processed Placental Tissue as an Innovative Approach in the Management of Acute Military-Related Injuries, Addressing a Critical Unmet Need

MARIETTA, Ga., May 31, 2022 (GLOBE NEWSWIRE) -- MiMedx Group, Inc. (Nasdaq: MDXG) (“MIMEDX” or the “Company”), a transformational placental biologics company, today announced receiving a $4.6 Million award to evaluate PURION^® processed Dehydrated Human Amnion Chorion Membrane (DHACM) as an advanced treatment option for wound and burn care. The award from the Medical Technology Enterprise Consortium (MTEC), a 501(c)(3) biomedical technology consortium collaborating under an Other Transaction Agreement (OTA) with the U.S. Army Medical Research and Development Command, is sponsored and will be managed by the Naval Medical Research Center (NMRC) to advance medical treatments for combat wounds and burns.

Advanced wound and burn treatment approaches that can be applied quickly and easily in military relevant environments are needed to provide better outcomes for U.S. Armed Forces personnel. According to a 2018 study published in the Journal of Burns, burn injuries accounted for almost 10% of all combat casualties suffered by frontline military personnel during Operations Enduring Freedom and Iraqi Freedom. Despite best medical efforts, the mortality rate is dramatically higher for the warfighters who cannot be evacuated quickly from the field to higher-level trauma facilities, as the management of thermal wounds and combat related burn casualties can be very challenging in the deployed environment.

“As a former U.S. Army Green Beret and Medical Corps Officer, I saw firsthand the urgent need for improved wound and burn treatment,” noted F. Raymond Ortega, MD, MBA, FACS, Vice President, Strategic Initiatives R&D, at MIMEDX. “This award will be used to advance the clinical understanding of DHACM, specifically in treating acute injuries and preventing initially partial-thickness burns from deteriorating to full-thickness burns, which can be life threatening. We also hope to leverage these data to understand how DHACM may reduce morbidity, limit the need for additional skin grafting, and expedite return to duty.”

To address combat and burn injuries, NMRC funded the award that will be directed toward research evaluating wound healing and burn conversion prevention capabilities of DHACM. The University of Arizona will lead pilot and pivotal randomized controlled trials to test study design, safety, and efficacy of wound healing. The clinical pilot study and the pivotal randomized controlled trial for burn conversion prevention will be conducted by the University of Miami.

“Following a solicitation process for Advanced Biomedical Product Development proposals in the area of Combat Casualty Wound and Infection Care in support of Naval Operations, MIMEDX was selected for an award to accelerate essential pre-clinical and clinical research that may offer improved burn care and innovative treatment for the warfighter,” said Mr. Thomas Dunn, Acting Program Manager for Naval Advanced Medical Development “There is a need to identify novel treatments that can demonstrate clinical effectiveness, accommodate logistical requirements, and, importantly, improve survival and convalescence rates for those suffering from challenging combat-related wounds and burns. Collaborating with industry and academia will enable development of state-of-the-art technologies and materials that promise to improve treatment outcomes and elevate the standard of care.”

“We have long recognized the immense potential and demonstrated benefits of placental biologics in a broad range of clinical settings and disease states,” said Timothy R. Wright, MIMEDX Chief Executive Officer. “It is a privilege to serve our nation through science and collaboration with academia and the U.S. Navy — utilizing our demonstrated expertise in placental biologics to support their goal of improving treatment for the service members who risk their lives for the sake of our safety and security.”

About MIMEDX

MIMEDX is a transformational placental biologics company, developing and distributing placental tissue allografts with patent-protected, proprietary processes for multiple sectors of healthcare. As a pioneer in placental tissue engineering, we have both a commercial business, focused on addressing the needs of patients with acute and chronic non-healing wounds, and a promising late-stage pipeline targeted at decreasing pain and improving function for patients with degenerative musculoskeletal conditions. We derive our products from human placental tissues and process these tissues using our proprietary methods, including the PURION^® process. We employ Current Good Tissue Practices, Current Good Manufacturing Practices, and terminal sterilization to produce our allografts. MIMEDX has supplied over two million allografts, through both direct and consignment shipments. For additional information, please visit www.mimedx.com.

About Medical Technology Enterprise Consortium (MTEC)

The Medical Technology Enterprise Consortium is a biomedical technology consortium collaborating with multiple government agencies under a 10-year renewable Other Transaction Agreement with the U.S. Army Medical Research and Development Command. The consortium focuses on the development of medical solutions that protect, treat, and optimize the health and performance of U.S. military personnel. To find out more about MTEC, visit www.mtec-sc.org.

Contacts
Investors:
Jack Howarth
Investor Relations
404.360.5681
jhowarth@mimedx.com

Media:
Hilary Dixon
Corporate & Strategic Communications
404.323.4779
hdixon@mimedx.com

FAQ

What is the purpose of Mimedx's $4.6 million award?

The award is designated for evaluating the PURION processed DHACM as a treatment for combat wounds and burns.

Which organization awarded Mimedx the funding?

The funding was awarded by the Medical Technology Enterprise Consortium (MTEC) in collaboration with the U.S. Army.

What types of injuries is Mimedx focusing on with this funding?

Mimedx is focusing on acute military-related injuries, particularly wounds and burns.

Who will conduct the clinical trials for the DHACM evaluation?

The clinical trials will be led by the University of Arizona and the University of Miami.

How does the funding impact Mimedx Group's business?

The funding allows Mimedx to advance its clinical research and potentially improve treatment outcomes for military personnel.