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Lyell Immunopharma, Inc. - LYEL STOCK NEWS

Welcome to our dedicated page for Lyell Immunopharma news (Ticker: LYEL), a resource for investors and traders seeking the latest updates and insights on Lyell Immunopharma stock.

Lyell Immunopharma, Inc. (Nasdaq: LYEL) is a clinical-stage company pioneering T-cell reprogramming to create cell therapies for patients with solid tumors. By employing advanced genetic and epigenetic technologies, Lyell aims to overcome major challenges in current cell-based immunotherapies, including T-cell exhaustion and lack of durable stemness. Their innovative approach has led to a robust pipeline featuring product candidates like LYL797, LYL119, and LYL845.

Lyell's product portfolio is designed to address the unmet needs in cancer treatment. LYL797 targets ROR1-positive cancers such as triple-negative breast cancer and non-small cell lung cancer, incorporating genetic reprogramming to overexpress c-Jun and epigenetic reprogramming for enhanced durability. LYL119 is another ROR1-targeted CAR T-cell therapy that uses four reprogramming technologies for sustained function and cytotoxicity. LYL845, a tumor-infiltrating lymphocyte (TIL) product, is enhanced with Lyell's proprietary Epi-R™ protocol to improve potency and durability.

Recent achievements include the FDA granting Orphan Drug Designation for LYL845 in advanced melanoma. The company's innovative Epi-R P2 manufacturing process has shown potential to reduce TIL culture time significantly. Lyell is also advancing collaborations, such as with Outpace Bio, to develop localized IL-12 activity in tumors, enhancing the efficacy of T-cell therapies.

Lyell's business strategy has been bolstered by a strong financial position, with cash reserves extending operational capabilities into 2027. Despite macroeconomic challenges, Lyell continues to focus on generating clinical data and advancing its clinical programs, aiming to deliver transformative treatments for cancer patients.

For the latest updates on Lyell Immunopharma, including their financial performance and ongoing clinical trials, visit their official website.

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Lyell Immunopharma, a clinical-stage company specializing in T-cell reprogramming for solid tumor cell therapies, announced participation in the Goldman Sachs 45th Annual Global Healthcare Conference. The event is scheduled for June 10 at 4:00 pm ET. Senior management will present during this conference, and a live webcast will be accessible through Lyell's investor section on www.lyell.com. A replay will also be made available post-presentation.

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Lyell Immunopharma, a clinical-stage T-cell reprogramming company, will participate in the BofA Securities Health Care Conference on May 14, 2024. The company will showcase its diverse pipeline of cell therapies for solid tumors. Investors can access the live webcast on the Company's website.

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Lyell Immunopharma, Inc. (Nasdaq: LYEL) reported business highlights for Q1 2024, including strong financial position with $526.3 million in cash and ongoing advancement of diverse cell therapy pipeline. Key updates include initial clinical data expected for LYL797 and LYL845, IND submission for LYL119, and promising nonclinical data presented at AACR Annual Meeting 2024.

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Lyell Immunopharma, Inc. (LYEL) announced the acceptance of three abstracts for presentation at the AACR Annual Meeting 2024. The abstracts include data on Lyell's rejuvenation technology, LYL119 CAR T-cell therapy, and tumor-restricted IL-12 technology.
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Lyell Immunopharma, Inc. (LYEL) reported financial results and business highlights for Q4 and FY 2023. They are on track to report initial clinical data in 2024, received Orphan Drug Designation for LYL845, and plan to submit an IND for a new CAR T-cell product. Cash position of $562.7 million supports operations into 2027.
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Lyell Immunopharma, Inc. (LYEL) will be presenting at TD Cowen's 44th Annual Health Care Conference and H.C. Wainwright 2nd Annual Cell Therapy Virtual Conference. The company is a clinical-stage T-cell reprogramming firm with a pipeline of cell therapies for solid tumors.
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Lyell Immunopharma, Inc. (Nasdaq: LYEL) to present at 42nd Annual J.P. Morgan Healthcare Conference, showcasing their diverse pipeline of cell therapies for solid tumors.
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Lyell Immunopharma, Inc. (Nasdaq: LYEL) announced that the FDA granted Orphan Drug Designation to LYL845, a TIL product candidate for stage IIB-IV melanoma treatment, with potential for better outcomes in other solid tumors. Initial clinical data from the Phase 1 trial are expected in 2024.
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Lyell Immunopharma, Inc. (Nasdaq: LYEL) reports financial results and business highlights, extending funding into 2027, with cash, cash equivalents, and marketable securities of $598.2 million as of September 30, 2023. They remain on track to release initial clinical data from two clinical-stage product candidates in 2024 and have entered into a manufacturing collaboration with Cellares for a CAR T cell product candidate.
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Lyell Immunopharma, Inc. is presenting new nonclinical data at the 38th Annual Meeting of the Society for Immunotherapy of Cancer. The presentations focus on innovations to shorten tumor infiltrating lymphocyte (TIL) manufacturing, new nonclinical data on LYL119, new technologies, and the design of two clinical trials in progress.
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FAQ

What is the current stock price of Lyell Immunopharma (LYEL)?

The current stock price of Lyell Immunopharma (LYEL) is $0.6127 as of December 20, 2024.

What is the market cap of Lyell Immunopharma (LYEL)?

The market cap of Lyell Immunopharma (LYEL) is approximately 177.3M.

What does Lyell Immunopharma do?

Lyell Immunopharma is a clinical-stage company focusing on T-cell reprogramming to develop cell therapies for patients with solid tumors.

What are Lyell's main product candidates?

Lyell's main product candidates include LYL797, a ROR1-targeted CAR T-cell therapy; LYL119, another ROR1-targeted CAR T-cell product; and LYL845, an enhanced TIL therapy.

What recent achievements has Lyell reported?

Lyell recently received FDA Orphan Drug Designation for LYL845 in advanced melanoma and has advanced collaborations to enhance T-cell therapies.

What technologies does Lyell use in their therapies?

Lyell employs ex vivo genetic and epigenetic reprogramming technologies to tackle barriers like T-cell exhaustion and lack of durable stemness.

What is the financial outlook for Lyell?

As of March 31, 2024, Lyell reported cash reserves sufficient to fund operations into 2027, keeping them focused on advancing their clinical programs.

Where is Lyell Immunopharma located?

Lyell Immunopharma is based in South San Francisco, California, with additional facilities in Seattle and Bothell, Washington.

What is Epi-R™ manufacturing protocol?

Epi-R™ is Lyell's proprietary epigenetic reprogramming protocol designed to enhance the potency and durability of TIL products.

What type of cancers are Lyell's therapies targeting?

Lyell's therapies target a variety of solid tumors, including triple-negative breast cancer, non-small cell lung cancer, and advanced melanoma.

How can I get updates on Lyell Immunopharma's developments?

You can visit their official website at www.lyell.com for the latest updates and detailed information on their projects and clinical trials.

What is Lyell's approach to addressing T-cell exhaustion?

Lyell's approach includes using genetic and epigenetic reprogramming technologies to create T cells with improved durability and ability to resist exhaustion.

Lyell Immunopharma, Inc.

Nasdaq:LYEL

LYEL Rankings

LYEL Stock Data

177.30M
233.13M
14.06%
62.68%
3.44%
Biotechnology
Pharmaceutical Preparations
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United States of America
SOUTH SAN FRANCISCO