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Leap Therapeutics, Inc. - LPTX STOCK NEWS

Welcome to our dedicated page for Leap Therapeutics news (Ticker: LPTX), a resource for investors and traders seeking the latest updates and insights on Leap Therapeutics stock.

Leap Therapeutics, Inc. (Nasdaq: LPTX) is a pioneering clinical-stage biopharmaceutical company focused on developing novel targeted antibody therapies for cancer treatment. Headquartered in Cambridge, Massachusetts, Leap Therapeutics aims to discover and advance transformative cancer treatments by targeting tumor-promoting pathways, cancer-specific cell surface molecules, and activating the immune system against cancer cells.

The company's lead program, DKN-01, is a humanized monoclonal antibody that targets Dickkopf-related protein 1 (DKK1). This promising candidate is in clinical trials for treating esophagogastric, gynecologic, and colorectal cancers. Another key program, FL-301, targets Claudin18.2-expressing cells and is being developed for gastric and pancreatic cancer treatments. Leap Therapeutics also has two preclinical antibody programs, FL-302 and FL-501, which are advancing toward developing innovative cancer therapies.

Operating as a single segment dedicated to oncology, Leap Therapeutics has established several strategic collaborations to enhance its development pipeline, including a clinical collaboration with BeiGene for the DisTinGuish trial and partnerships with NovaRock Biotherapeutics and Adimab. The company's dedication to advancing targeted and immuno-oncology therapeutics underscores its commitment to addressing unmet needs in cancer treatment. Leap's research and development activities continue to make significant progress, with ongoing clinical trials and new data demonstrating the potential efficacy and safety of its therapeutic candidates.

In recent news, Leap Therapeutics announced the completion of enrollment in the randomized controlled Part C of the DisTinGuish study, evaluating DKN-01 in combination with tislelizumab and chemotherapy for advanced gastroesophageal junction and gastric cancer. Additionally, the company reported financial results for the first quarter of 2024, highlighting a successful $40 million financing that extends its cash runway into the second quarter of 2026. This funding will support the expansion and continued execution of the DKN-01 development program, including the expansion of the randomized controlled Part B of the DeFianCe study in second-line colorectal cancer patients.

For more information about Leap Therapeutics, visit www.leaptx.com or view their public filings with the SEC available via EDGAR at www.sec.gov or www.investors.leaptx.com.

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Leap Therapeutics (Nasdaq: LPTX) announced that its CEO, Douglas E. Onsi, will present a corporate overview at the Raymond James Institutional Investors Conference in Orlando from March 6-9, 2022. The presentation is scheduled for March 9 at 7:30 a.m. ET and will be available via live webcast on the company's Investors page. Leap focuses on developing targeted and immuno-oncology therapeutics, with its leading candidate, DKN-01, in trials for various cancers. A replay of the event will be accessible post-presentation.

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Leica Biosystems has partnered with Leap Therapeutics (NASDAQ: LPTX) to create a companion diagnostic for detecting Dickkopf-related protein 1 (DKK1), a protein associated with poor cancer outcomes. This diagnostic will support the clinical development of Leap's DKN-01 therapy, a humanized monoclonal antibody currently in Phase 2 trials for gastric cancer. The test employs RNAscope™ technology to identify patients likely to benefit from DKN-01. This collaboration aims to enhance personalized cancer treatment based on biomarker profiles.

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Leap Therapeutics (Nasdaq: LPTX), a biotechnology firm specializing in targeted and immuno-oncology therapies, will present a corporate overview at the B. Riley Securities Oncology Investor Conference on January 27, 2022, at 10:00 a.m. Eastern Time. The event will be virtual and accessible via the company’s website, where a replay will also be available. Leap's leading candidate, DKN-01, targets the Dickkopf-1 protein and is currently in clinical trials for various cancers. A partnership with BeiGene has been established for developing DKN-01 in Asia, Australia, and New Zealand.

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Leap Therapeutics (Nasdaq: LPTX) announced that updated data from the DisTinGuish Phase 2a trial will be presented at the ASCO Gastrointestinal Cancers Symposium from January 20-22, 2022. The trial evaluates DKN-01, an anti-DKK1 antibody, combined with BeiGene's tislelizumab in patients with gastric and gastroesophageal junction cancer. Notable findings show promising efficacy in DKK1-high patients and improved safety tolerability. A conference call is scheduled for January 21, 2022, to discuss the results. The study is ongoing, focusing on both first-line and second-line therapies.

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Leap Therapeutics (Nasdaq: LPTX) announced that its President and CEO, Douglas E. Onsi, will present a corporate overview at the H.C. Wainwright BioConnect 2022 Conference from January 10-13, 2022. The presentation will be available on January 10 at 7:00 a.m. Eastern Time via their Investors page.

The company focuses on developing targeted and immuno-oncology therapeutics, with DKN-01 as their lead candidate currently in trials for various cancers.

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Leap Therapeutics (Nasdaq: LPTX) will present a corporate overview at the 40th Annual J.P. Morgan Healthcare Conference on January 13, 2022, at 9:00 a.m. Eastern Time. Douglas E. Onsi, President and CEO, will lead the presentation, which will be accessible via a live webcast on the company's Investors page. Leap Therapeutics focuses on developing targeted therapies, including DKN-01, a monoclonal antibody in clinical trials for various cancers. For more information, visit www.leaptx.com.

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Leap Therapeutics, Inc. (Nasdaq: LPTX) announced participation in the Piper Sandler 33rd Annual Virtual Healthcare Conference from November 29 to December 2, 2021. Members of the senior management team will engage in a fireside chat, with a replay available on the company’s Investors page starting November 22, 2021, at 10:00 a.m. ET. Leap is focused on developing targeted immuno-oncology therapeutics, with its lead candidate, DKN-01, currently in trials for various cancers. For more details, visit Leap's website.

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Leap Therapeutics (Nasdaq:LPTX) reported its third quarter financial results for 2021, revealing a net loss of $11.1 million, up from $7.1 million in Q3 2020. The company successfully completed a $103.6 million public offering, netting $96.8 million. Positive initial data from the DisTinGuish Study of DKN-01 plus tislelizumab indicated a 68.2% overall response rate in first-line gastric cancer patients. R&D expenses rose to $10.1 million, attributed to increased clinical trial costs and staffing. Cash and equivalents stood at $124.8 million as of September 30, 2021.

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Leap Therapeutics, Inc. (Nasdaq:LPTX) closed a public offering of 27,568,072 shares of common stock, raising approximately $104 million. This amount includes $7.25 million from collaborator BeiGene, Ltd. The offering included the additional sale of 4,740,000 shares due to underwriters' exercised options and 8,771,928 pre-funded warrants. Piper Sandler, Raymond James, and Mizuho acted as book-running managers. Proceeds will assist in advancing Leap's clinical programs, particularly for their leading candidate, DKN-01, which targets various cancers.

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Leap Therapeutics (Nasdaq:LPTX) announced a public offering of common stock priced at $2.85 per share, alongside pre-funded warrants at $2.849 each. This offering is projected to raise approximately $90 million in gross proceeds, anticipated to close around September 24, 2021. The company will use the funds for further development of its drug candidate DKN-01, manufacturing clinical trial materials, and general corporate purposes. The offering includes an option for underwriters to purchase an additional 4,740,000 shares.

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FAQ

What is the current stock price of Leap Therapeutics (LPTX)?

The current stock price of Leap Therapeutics (LPTX) is $2.91 as of December 24, 2024.

What is the market cap of Leap Therapeutics (LPTX)?

The market cap of Leap Therapeutics (LPTX) is approximately 111.5M.

What does Leap Therapeutics, Inc. specialize in?

Leap Therapeutics specializes in developing targeted antibody therapies for cancer treatment, focusing on inhibiting tumor-promoting pathways, targeting cancer-specific cell surface molecules, and activating the immune system against cancer cells.

What is DKN-01?

DKN-01 is Leap Therapeutics' lead clinical candidate, a humanized monoclonal antibody targeting Dickkopf-related protein 1 (DKK1), being developed to treat esophagogastric, gynecologic, and colorectal cancers.

What are the latest developments in Leap Therapeutics' clinical trials?

Recent developments include the completion of enrollment in the Part C of the DisTinGuish study evaluating DKN-01 with tislelizumab and chemotherapy for advanced gastroesophageal junction and gastric cancer, and the expansion of the Part B of the DeFianCe study for second-line colorectal cancer.

Who are Leap Therapeutics' collaboration partners?

Leap Therapeutics collaborates with BeiGene for the DisTinGuish trial and has partnerships with NovaRock Biotherapeutics and Adimab.

What are the financial highlights from Leap Therapeutics' latest quarter?

For the first quarter of 2024, Leap Therapeutics reported a net loss of $13.8 million. Cash and cash equivalents totaled $54.9 million at the end of March 31, 2024. The company also completed a $40 million financing round in April 2024.

Where is Leap Therapeutics headquartered?

Leap Therapeutics is headquartered in Cambridge, Massachusetts.

What is FL-301?

FL-301 is one of Leap Therapeutics' clinical programs targeting Claudin18.2-expressing cells, being developed for gastric and pancreatic cancer treatments.

How does Leap Therapeutics plan to use the recent $40 million financing?

Leap Therapeutics intends to use the net proceeds to fund the continued development of its lead monoclonal antibody program, DKN-01, expand the randomized controlled Part B of the DeFianCe Study, enable data maturity in the Part C of the DisTinGuish study, and manufacture clinical trial material for Phase 3 readiness.

What are Leap Therapeutics' preclinical programs?

Leap Therapeutics has preclinical antibody programs, FL-302 and FL-501, which are aimed at developing new cancer treatments.

How can one access Leap Therapeutics' public filings?

Public filings can be accessed via EDGAR at the SEC's website (www.sec.gov) or through Leap Therapeutics' investor relations page (www.investors.leaptx.com).

Leap Therapeutics, Inc.

Nasdaq:LPTX

LPTX Rankings

LPTX Stock Data

111.51M
31.69M
17.29%
40.3%
2.64%
Biotechnology
Pharmaceutical Preparations
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United States of America
CAMBRIDGE