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Liminal BioSciences Inc. - LMNL STOCK NEWS

Welcome to our dedicated page for Liminal BioSciences news (Ticker: LMNL), a resource for investors and traders seeking the latest updates and insights on Liminal BioSciences stock.

Liminal BioSciences Inc. (NASDAQ: LMNL) is a clinical-stage biopharmaceutical company dedicated to the discovery, development, and commercialization of innovative treatments for diseases with unmet medical needs. Established originally as Prometic Life Sciences Inc., the company rebranded to its current name in October 2019 to better reflect its evolving mission.

The company operates through two core segments: Small Molecule Therapeutics and Plasma Derived Therapeutics. The Small Molecule Therapeutics segment is spearheaded by its lead product candidate, Fezagepras (PBI-4050), aimed at treating idiopathic pulmonary fibrosis, respiratory diseases, and Alström Syndrome. In parallel, the Plasma Derived Therapeutics segment focuses on plasma protein purification technologies, particularly for extracting therapeutic proteins from human plasma. One of its notable developments is Ryplazim, designed for treating congenital plasminogen deficiency.

Liminal BioSciences has a geographically diverse operational footprint with active business operations in Canada, the United Kingdom, and the United States. Reflecting its commitment to cutting-edge research, the company has a deep pipeline of projects including LMNL6511, LMNL6326, and GPR40 agonists, each targeting various metabolic, inflammatory, and fibrotic diseases.

Financially, Liminal BioSciences recently announced a definitive arrangement agreement with Structured Alpha LP (SALP) under which SALP will acquire all outstanding common shares of the company at a significant premium, solidifying investor confidence in the company's strategic direction. The transaction is expected to close by the end of September 2023, pending necessary approvals and conditions.

Overall, Liminal BioSciences stands at the forefront of biopharmaceutical innovation, driven by its integrated drug discovery platform, medicinal chemistry expertise, and a robust understanding of GPCR biology. The company's collaborations and partnerships further reinforce its potential to deliver transformative healthcare solutions to patients worldwide.

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Liminal BioSciences (Nasdaq: LMNL) announced a strategic shift focusing on its small molecule therapeutics platform, including fezagepras, while evaluating options for its plasma-derived therapeutics business. The company aims to minimize cash burn and streamline operations by divesting non-core assets. Currently, efforts to partner for Ryplazim have not yielded results, prompting this evaluation. The FDA has set a target action date of June 5, 2021 for Ryplazim's Biologic License Application.

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Liminal BioSciences Inc. (Nasdaq: LMNL) announced FDA approval for its plasma collection center in Amherst, NY, marking a significant milestone as it expands operations in the U.S. This center, operational since early 2020, is now licensed to trade human source plasma, enhancing Liminal's ability to supply raw materials for its biopharmaceutical products. The FDA inspection that preceded this approval was conducted in September 2020. This strategic move allows Liminal to meet growing demand and support its clinical programs, which include treatments for diseases related to fibrosis and congenital plasminogen deficiency.

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Liminal BioSciences (Nasdaq: LMNL) has initiated a Phase 1 clinical trial for fezagepras, an anti-inflammatory and anti-fibrotic small molecule. The trial involves healthy volunteers and aims to evaluate multiple ascending doses over 14 days, focusing on safety and pharmacokinetics. This study will help determine the optimal dosing regimen for future Phase 2 trials targeting idiopathic pulmonary fibrosis (IPF). Fezagepras has received Orphan Drug Designation from the FDA and EMA, with a global Phase 2b trial expected to start in H2-2021.

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Liminal BioSciences Inc. (Nasdaq: LMNL) announced that CEO Bruce Pritchard will present a company overview at The Stifel 2020 Virtual Healthcare Conference on November 16, from 2:40 to 3:10 PM (EDT). The presentation will be webcast live, with an archived replay available for seven days. Liminal is a clinical-stage biopharmaceutical company focused on developing treatments for diseases like fibrosis. Their lead candidate, fezagepras, is set to enter Phase 1 trials in Q4-2020. Liminal also aims to submit a BLA for Ryplazim® to treat congenital plasminogen deficiency, with a PDUFA date of June 5, 2021.

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Liminal BioSciences (Nasdaq: LMNL) reported its Q3 2020 financial results, highlighting a net loss of $23.3 million, down 22% from the previous year. The company announced a PDUFA target date of June 5, 2021 for Ryplazim® (plasminogen) following its BLA resubmission to the FDA. It secured $30 million from a private placement and C$29.1 million in a long-term loan from its largest shareholder. Executive changes were noted, with Bruce Pritchard stepping in as CEO, and a focus on advancing clinical trials and commercialization strategies.

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Liminal BioSciences Inc. (Nasdaq: LMNL) will report its Q3 financial results after market close on November 12, 2020. A conference call to discuss these results is scheduled for November 13, 2020, at 8:30 AM ET. The company is focused on developing treatments for fibrosis-related diseases. Their lead product, fezagepras, is set to enter Phase 1 trials in Q4-2020 and has Orphan Drug Designation for idiopathic pulmonary fibrosis. Additionally, Liminal is progressing its product Ryplazim, aiming for FDA approval by June 5, 2021.

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Liminal BioSciences Inc. (Nasdaq: LMNL) announced an extension of the FDA review period for its Biologics License Application (BLA) for Ryplazim® from March 5, 2021 to June 5, 2021. This decision follows a major amendment submission containing new manufacturing information. CEO Kenneth Galbraith expressed disappointment but remains committed to discussions with the FDA. A corporate update call is scheduled for November 11, 2020, to discuss these developments.

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Liminal BioSciences Inc. (Nasdaq: LMNL) will announce its third-quarter financial results for the period ending September 30, 2020, on November 12, 2020, after market close. A conference call is scheduled for November 13, 2020, at 8:30 AM ET, accessible via phone or audio webcast. The company focuses on developing treatments for fibrotic diseases and is moving forward with clinical trials for its lead candidate, fezagepras. The BLA for Ryplazim, targeting congenital plasminogen deficiency, has been resubmitted with a PDUFA date of March 5, 2021.

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Liminal BioSciences Inc. (NASDAQ: LMNL) announced acceptance of two abstracts for Ryplazim® at the 62nd American Society of Hematology Meeting from December 5-8, 2020. Ryplazim® is under development for treating Congenital Plasminogen Deficiency (C-PLGD), with a Biologic License Application submitted in September 2020. The abstracts highlight successful treatments and their implications for patients. With no current approved therapies for C-PLGD, Ryplazim® represents a vital potential option.

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Liminal BioSciences (Nasdaq: LMNL) announced a private placement to raise approximately USD $30 million through the sale of 5,757,894 common shares and 557,894 pre-funded warrants. The funds will support clinical development for fezagepras and the FDA review of the BLA for Ryplazim®. The placement is led by a prominent U.S. public investment fund and will close around November 3, 2020. Liminal BioSciences aims to register the resale of these securities with the SEC within 30 days following the closing.

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FAQ

What is the market cap of Liminal BioSciences (LMNL)?

The market cap of Liminal BioSciences (LMNL) is approximately 27.6M.

What does Liminal BioSciences Inc. specialize in?

Liminal BioSciences specializes in the discovery, development, and commercialization of novel treatments for diseases with unmet medical needs, focusing on small molecule therapeutics and plasma-derived therapeutics.

What is the lead product candidate of Liminal BioSciences?

The lead product candidate is Fezagepras (PBI-4050), which is aimed at treating idiopathic pulmonary fibrosis, respiratory diseases, and Alström Syndrome.

In which regions does Liminal BioSciences operate?

Liminal BioSciences operates in Canada, the United Kingdom, and the United States.

What recent significant transaction has Liminal BioSciences engaged in?

Liminal BioSciences has entered into a definitive arrangement agreement with Structured Alpha LP (SALP) to acquire all outstanding common shares at a substantial premium. This transaction is anticipated to close by the end of September 2023.

What is Ryplazim and what does it treat?

Ryplazim is a plasma protein purification product developed by Liminal BioSciences for the treatment of congenital plasminogen deficiency.

How does Liminal BioSciences contribute to the biopharmaceutical field?

Liminal BioSciences contributes through its integrated drug discovery platform, medicinal chemistry expertise, and deep understanding of GPCR biology to create potential best-in-class therapeutics for metabolic, inflammatory, and fibrotic diseases.

What are some products in Liminal BioSciences' pipeline?

The company's pipeline includes LMNL6511, LMNL6326, and GPR40 agonists, which target various metabolic, inflammatory, and fibrotic diseases.

What is the significance of the recent agreement with SALP for Liminal BioSciences?

The agreement with SALP, involving the acquisition of all outstanding shares, underscores investor confidence and provides Liminal BioSciences with significant financial backing to continue its innovative research and development efforts.

What was the former name of Liminal BioSciences Inc.?

The company was formerly known as Prometic Life Sciences Inc. before rebranding in October 2019.

Are there any ongoing clinical trials for Liminal BioSciences' products?

Yes, the selective antagonist LMNL6511 for the GPR84 receptor is expected to commence a Phase 1 clinical trial in the second half of 2023.

Liminal BioSciences Inc.

Nasdaq:LMNL

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LMNL Stock Data

27.62M
1.26M
61.26%
0.77%
0.02%
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