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Liminal BioSciences Inc. (NASDAQ: LMNL) is a clinical-stage biopharmaceutical company dedicated to the discovery, development, and commercialization of innovative treatments for diseases with unmet medical needs. Established originally as Prometic Life Sciences Inc., the company rebranded to its current name in October 2019 to better reflect its evolving mission.
The company operates through two core segments: Small Molecule Therapeutics and Plasma Derived Therapeutics. The Small Molecule Therapeutics segment is spearheaded by its lead product candidate, Fezagepras (PBI-4050), aimed at treating idiopathic pulmonary fibrosis, respiratory diseases, and Alström Syndrome. In parallel, the Plasma Derived Therapeutics segment focuses on plasma protein purification technologies, particularly for extracting therapeutic proteins from human plasma. One of its notable developments is Ryplazim, designed for treating congenital plasminogen deficiency.
Liminal BioSciences has a geographically diverse operational footprint with active business operations in Canada, the United Kingdom, and the United States. Reflecting its commitment to cutting-edge research, the company has a deep pipeline of projects including LMNL6511, LMNL6326, and GPR40 agonists, each targeting various metabolic, inflammatory, and fibrotic diseases.
Financially, Liminal BioSciences recently announced a definitive arrangement agreement with Structured Alpha LP (SALP) under which SALP will acquire all outstanding common shares of the company at a significant premium, solidifying investor confidence in the company's strategic direction. The transaction is expected to close by the end of September 2023, pending necessary approvals and conditions.
Overall, Liminal BioSciences stands at the forefront of biopharmaceutical innovation, driven by its integrated drug discovery platform, medicinal chemistry expertise, and a robust understanding of GPCR biology. The company's collaborations and partnerships further reinforce its potential to deliver transformative healthcare solutions to patients worldwide.
Liminal BioSciences Inc. (Nasdaq: LMNL) will report its third quarter 2022 financial results after market close on November 9, 2022. A conference call and webcast will be held on November 10, 2022, at 8:30 am (ET) to discuss the results. The company focuses on developing small molecule therapeutics for inflammatory, fibrotic, and metabolic diseases, including GPR84 and OXER1 antagonists. Liminal BioSciences operates in Canada and the UK, and it emphasizes a data-driven approach to drug discovery.
Liminal BioSciences Inc. (Nasdaq: LMNL) has received approval to transfer its common shares from The Nasdaq Global Market to The Nasdaq Capital Market, starting September 6, 2022. This transfer follows a notice from Nasdaq regarding non-compliance with the minimum bid price of $1.00 per share. The company has been granted an additional 180 days until February 27, 2023, to regain compliance, potentially through a reverse stock split. Liminal BioSciences focuses on developing novel therapeutics for inflammatory, fibrotic, and metabolic diseases.
Liminal BioSciences Inc. (Nasdaq: LMNL), a biopharmaceutical company, will present an overview at the H.C. Wainwright 24th Annual Global Investment Conference on September 14, 2022, at 09:30 am ET. CEO Bruce Pritchard will lead the presentation at The Lotte New York Palace. The event runs from September 12-14. Interested parties can access the presentation on the company's website for a week post-event. Liminal BioSciences focuses on developing novel therapeutics for various diseases.
Liminal BioSciences Inc. (Nasdaq: LMNL) announced the immediate termination of its legacy Master Services Agreement related to its former plasma-derived therapeutics business, with expected cash savings of $33.1 million. This decision eliminates all financial commitments related to the agreement, which included a yearly minimum purchase of $9 million. The termination will cost the company $18 million, with payments scheduled over 2023 and 2024. This move aligns with Liminal's strategy to streamline operations and divest non-core assets.
Liminal BioSciences Inc. (Nasdaq: LMNL) reported its Q2 2022 financial results, highlighting a net loss of $6.5 million, a significant reduction from $12.6 million in Q2 2021. The company had cash and equivalents of $55.8 million as of June 30, 2022. Administrative expenses dropped by 46% to $4.6 million primarily due to decreased insurance costs. Notably, the company discontinued the development of fezagepras based on unfavorable clinical trial results, refocusing on its GPR84 and OXER1 antagonist programs.
Liminal BioSciences (Nasdaq: LMNL) announced the discontinuation of fezagepras development following a Phase 1a trial that showed it was inferior to Sodium Phenylbutyrate as a nitrogen scavenger. This decision allows the company to focus on preclinical programs, including GPR84 and OXER1 antagonists targeting inflammatory and metabolic conditions. The CEO, Bruce Pritchard, emphasized that this move aligns with their strategic focus and is not related to safety concerns.
Liminal BioSciences Inc. (Nasdaq: LMNL) announced the results from its Annual General Meeting of Shareholders (AGM) held on June 6, 2022, where 20,209,035 common shares were voted, accounting for 65.10% of the total. All six director nominees were elected, with significant majorities: Simon Best received 98.93% approval. PricewaterhouseCoopers LLP was appointed as auditors. The company, focused on developing new therapeutics for inflammatory and metabolic diseases, is advancing its lead product candidate, fezagepras, currently in clinical trials.
Liminal BioSciences announced the initiation of its Phase 1a clinical trial for fezagepras, with the first subject dosed. This single ascending dose trial aims to compare the safety and pharmacokinetics of fezagepras with Sodium Phenylbutyrate in healthy volunteers. CEO Bruce Pritchard emphasized that the results will determine the future development of fezagepras as a nitrogen scavenger therapy. The trial is part of Liminal's ongoing research into treatments for hyperammonaemia. An update on the trial's outcome is expected in Q3 2022.
Liminal BioSciences (NASDAQ: LMNL) reported its Q1 2022 financial results, highlighting a significant reduction in net loss to $11.2 million from $20.8 million in Q1 2021. The company eliminated $39.1 million in secured loans, freeing its assets for development. Research and development expenses decreased to $4.4 million from $4.9 million, while administration expenses fell by 40% to $4.9 million. A Phase 1a Single Ascending Dose clinical trial for fezagepras is set to begin in Q2 2022.
Liminal BioSciences Inc. (NASDAQ: LMNL) will report its first quarter 2022 financial results after market close on May 10, 2022. Following the release, a conference call is scheduled for 8:30 am ET on May 11, 2022, providing insights into the financial performance. The company focuses on developing novel therapeutics for inflammatory, fibrotic, and metabolic diseases. Its lead candidate, fezagepras, has completed Phase 1 trials, with further clinical trials anticipated in Q2 2022.
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