Lipella Pharmaceuticals Announces Abstract Publication at 2024 American Society of Clinical Oncology (ASCO) Annual Meeting
Lipella Pharmaceuticals (Nasdaq: LIPO) announced the publication of an abstract at the 2024 American Society of Clinical Oncology (ASCO) annual meeting. The abstract, titled “Intravesical Administration of Pembrolizumab for Bladder Tumor- A Potential Strategy to Minimize Drug Toxicity,” presents new preclinical data for LP-50, an intravesical formulation for treating non-muscle invasive bladder cancer (NMIBC).
The preclinical results indicate that LP-50 has the potential to increase efficacy while reducing systemic toxicity. Dr. Michael Chancellor, the Chief Medical Officer of Lipella, provided insights into these promising results. The ASCO annual meeting will take place from May 31 to June 4, 2024, in Chicago, IL, and online.
The American Cancer Society estimates there will be 83,190 new cases of bladder cancer diagnosed in the United States in 2024.
- Promising preclinical results for LP-50 in treating NMIBC.
- LP-50 shows potential for increased efficacy and reduced systemic toxicity.
- Publication at the prestigious 2024 ASCO annual meeting.
- The results are still in the preclinical stage, requiring further research before clinical application.
Abstract highlighting new preclinical data from LP-50 in non-muscle invasive bladder cancer
PITTSBURGH, May 29, 2024 (GLOBE NEWSWIRE) -- Lipella Pharmaceuticals Inc. (Nasdaq: LIPO) (“Lipella,” “our,” “us” or the “Company”), a clinical-stage biotechnology company addressing serious diseases with significant unmet need, today announces an abstract publication at the 2024 American Society of Clinical Oncology (ASCO) annual meeting, taking place from May 31 - June 4 in Chicago, IL, and online.
Lipella’s abstract, titled “Intravesical Administration of Pembrolizumab for Bladder Tumor- A Potential Strategy to Minimize Drug Toxicity” highlights new preclinical results from LP-50 (intravesical pembrolizumab) in induced murine non-muscle invasive bladder cancer (NMIBC). The abstract can be viewed at: https://meetings.asco.org/abstracts-presentations/235302.
Lipella Pharmaceuticals Chief Medical Officer, Dr. Michael Chancellor, said, “LP-50 is an intravesical formulation intended for the treatment of non-muscle invasive bladder cancer. Our preclinical results have demonstrated promising results, demonstrating LP-50’s potential for increasing efficacy while minimizing systemic toxicity.”
The American Cancer Society estimates that there will be 83,190 new cases of bladder cancer diagnosed in the United States in 2024.
About LP-50
LP-50 is an intravesical formulation of immunoglobulins including local, intravesical PD-1 (i.e. checkpoint) inhibition, intended for the treatment of non-muscle invasive bladder cancer (NMIBC), offering the potential for increasing efficacy while minimizing systemic toxicity. Additional information regarding this preclinical program is included in the International Journal of Molecular Sciences 2024, 25(9), 4945, titled "Enhancing Therapeutic Efficacy and Safety of Immune Checkpoint Inhibition for Bladder Cancer: A Comparative Analysis of Injectable vs. Intravesical Administration," as well as in US patent publication number 2024/0115503 titled "Intravesical Delivery of Hydrophilic Therapeutic Agents Using Liposomes."
About Lipella Pharmaceuticals Inc.
Lipella Pharmaceuticals is a clinical-stage biotechnology company focused on developing new drugs by reformulating the active agents in existing generic drugs and optimizing these reformulations for new applications. Additionally, Lipella maintains a therapeutic focus on diseases with significant, unaddressed morbidity and mortality where no approved drug therapy currently exists. Lipella completed its initial public offering in December 2022.
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CONTACT
Jonathan Kaufman
Chief Executive Officer
Lipella Pharmaceuticals Inc.
Info@Lipella.com
1-412-894-1853
PCG Advisory
Jeff Ramson
jramson@pcgadvisory.com
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