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LianBio - LIAN STOCK NEWS

Welcome to our dedicated page for LianBio news (Ticker: LIAN), a resource for investors and traders seeking the latest updates and insights on LianBio stock.

LianBio (LIAN) is a pioneering biotechnology company dedicated to accelerating the availability of transformative medicines to patients in China and major Asian markets. The company's mission involves forging partnerships with world-class biopharmaceutical firms to bring paradigm-shifting therapies to historically underserved regions.

Core Business: LianBio focuses on building a diversified portfolio of drug candidates that address significant unmet medical needs. The company's therapeutic focus spans multiple areas, including cardiovascular, oncology, ophthalmology, and inflammatory diseases. They employ a strategy of precision-based therapeutics and transformative mechanisms to impact patient outcomes substantially.

Recent Achievements: LianBio has been making notable strides in clinical development and regulatory milestones. Their product infigratinib, an ATP-competitive FGFR1-3 selective oral tyrosine kinase inhibitor, has shown promising results in a Phase 2 clinical trial for gastric cancer and gastroesophageal junction adenocarcinoma. The study demonstrated a confirmed objective response rate (cORR) of 23.8% and a disease control rate (DCR) of 76.2%, among other encouraging metrics. Infigratinib has received Breakthrough Therapy Designation from the China National Medical Products Administration (NMPA).

Current Projects: In addition to infigratinib, LianBio is advancing the clinical development of TP-03, a novel eye drop treatment for Demodex blepharitis. The Phase 3 LIBRA trial demonstrated significant mite eradication, positioning TP-03 for potential regulatory approval in China. The company is also involved in the Phase 1 clinical trial of BBP-398, a SHP2 inhibitor in combination with EGFR inhibitor osimertinib for non-small cell lung cancer (NSCLC) patients.

Financial Condition: For the third quarter of 2023, LianBio reported research and development expenses of $9 million and general and administrative expenses of $17.3 million. The company’s net loss for the same period was $24 million. Despite these expenditures, LianBio maintains a robust cash balance of $252.2 million, ensuring financial stability for ongoing and future projects.

Partnerships: LianBio collaborates with several high-caliber global biopharmaceutical companies, enhancing their capability to bring innovative treatments to market. Notably, they have licensed rights from QED Therapeutics and Tarsus Pharmaceuticals to develop and commercialize breakthrough therapies in China and other Asian territories.

Future Outlook: The company is currently undergoing a strategic review aimed at maximizing shareholder value, including the potential sale of pipeline assets and workforce reductions. LianBio continues to focus on providing access to innovative medicines, leveraging its international infrastructure and strategic partnerships to address critical health needs in the region.

For the latest updates and more detailed information, please visit www.lianbio.com.

Rhea-AI Summary
LianBio has entered into an agreement with Bristol Myers Squibb (BMS) for the exclusive rights to develop and commercialize mavacamten in several Asian markets. LianBio will receive $350 million upfront and be released from remaining milestone payments. The China National Medical Products Administration has accepted a New Drug Application for mavacamten. LianBio's Board of Directors has initiated a strategic review.
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LianBio presents positive data on mavacamten in Chinese oHCM patients at ESC 2023 and JAMA Cardiology
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LianBio reports financial results for Q2 2023 and provides updates on clinical development milestones. Mavacamten NDA under priority review in China. Positive results from EXPLORER-CN trial. Cash balance of $267.3 million. Anticipated milestones for mavacamten, TP-03, infigratinib, and BBP-398.
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LianBio has announced the dosing of the first patient in its Phase 1 clinical trial of BBP-398, an SHP2 inhibitor, in combination with AstraZeneca's osimertinib for the treatment of non-small cell lung cancer (NSCLC) with EGFR mutations. SHP2 overactivity is a critical contributor to cancer and resistance to targeted therapies. The trial aims to evaluate the safety, tolerability, pharmacokinetics, and anti-tumor activity of the combination therapy.
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Tarsus Pharmaceuticals received FDA approval for XDEMVY™ (lotlilaner ophthalmic solution) 0.25% to treat Demodex blepharitis, marking the first FDA-approved treatment targeting Demodex mites. LianBio, the partner of Tarsus, is conducting a Phase 3 trial in China and expects to report results in Q4 2023.
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LianBio announces clinical supply agreement with AstraZeneca in China to evaluate BBP-398 in combination with osimertinib for the treatment of NSCLC patients with EGFR mutations.
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FAQ

What is the market cap of LianBio (LIAN)?

The market cap of LianBio (LIAN) is approximately 34.5M.

What is LianBio’s mission?

LianBio aims to catalyze the development and accelerate the availability of transformative medicines to patients in China and major Asian markets through strategic partnerships.

What therapeutic areas does LianBio focus on?

LianBio focuses on cardiovascular, oncology, ophthalmology, and inflammatory diseases.

What recent clinical achievements has LianBio made?

LianBio's infigratinib has shown promising results in a Phase 2 clinical trial for gastric cancer, demonstrating a confirmed objective response rate of 23.8%.

What is TP-03?

TP-03 is a novel prescription eye drop developed by LianBio for the treatment of Demodex blepharitis, which has shown significant mite eradication in clinical trials.

Who are LianBio's key partners?

LianBio collaborates with QED Therapeutics, Tarsus Pharmaceuticals, and other global biopharmaceutical companies.

What is LianBio's financial outlook?

For the third quarter of 2023, LianBio reported a net loss of $24 million but maintains a strong cash balance of $252.2 million.

What is infigratinib?

Infigratinib is an ATP-competitive, FGFR1-3 selective oral tyrosine kinase inhibitor developed by LianBio for treating various cancers, including gastric cancer.

What markets does LianBio serve?

LianBio focuses on China and other major Asian markets.

How is LianBio's management adapting to recent changes?

LianBio is undergoing a strategic review to maximize shareholder value, including potential asset sales and workforce reductions.

Where can I find more information about LianBio?

For more information, visit LianBio's website at www.lianbio.com.
LianBio

Nasdaq:LIAN

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LIAN Stock Data

34.47M
25.38M
5.91%
78.99%
0.35%
Biotechnology
Healthcare
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