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Lexaria Bioscience Corp. (NASDAQ:LEXXW) is a global innovator in drug delivery platforms known for its patented drug delivery technology, DehydraTECH. DehydraTECH enhances the absorption of active pharmaceutical ingredients, such as cannabinoids and nicotine, by promoting more effective oral delivery. The technology has shown to significantly increase bio-absorption, reduce onset times, and mask unwanted tastes. Lexaria operates in four main segments: Intellectual Property Licensing, B2B Production, Research and Development, and Corporate. With a robust intellectual property portfolio and ongoing research, Lexaria aims to revolutionize drug delivery methods and improve outcomes.
Lexaria Bioscience Corp. has selected InClin, a California-based CRO, to manage its upcoming Phase 1b hypertension study, titled HYPER-H23-1, evaluating the safety and efficacy of its patented DehydraTECH-CBD. The study aims to assess the treatment on 120 patients with Stage 1 and Stage 2 hypertension, following successful FDA pre-IND meeting outcomes. Lexaria plans to file its IND application this summer, anticipating FDA authorization within 60 days. Previous studies indicated that DehydraTECH-CBD significantly reduced blood pressure with no serious adverse events, setting it apart from other CBD formulations. The company is also working on the necessary stability testing for its drug product, which is crucial for the IND submission.
Lexaria Bioscience Corp. (Nasdaq:LEXX)(Nasdaq:LEXXW) has announced the receipt of four new patents, enhancing its intellectual property portfolio globally. In Japan, a patent for Stable Ready-to-Drink Beverage Compositions marks the 5th awarded in the country; in Australia, a patent for Enhanced Delivery of Antiviral Agents becomes the 10th. Canada has allowed a patent for Nicotine Compounds, and the USA has granted a patent for Treating Hypertension, crucial for future FDA applications. These patents underscore Lexaria's commitment to expanding its DehydraTECH technology, vital in the lucrative cardiovascular drugs market projected to grow from US$146.5 billion in 2022 to $173.5 billion by 2026. With these additions, Lexaria's patent portfolio increases to 32 granted patents worldwide.
Lexaria Bioscience Corp. (Nasdaq: LEXX, LEXXW) has completed its diabetes study DIAB-A22-1, demonstrating significant positive effects of DehydraTECH-CBD on obese diabetic rats. Key outcomes include:
- Approximately 7% weight loss over 8 weeks, with treated animals losing weight while untreated animals gained weight.
- Improved metabolic function indicated by stable food and water intake despite weight loss.
- Significant reductions in triglyceride levels, with the lower dose achieving over 25% reduction compared to untreated rats.
- Potential enhancement of activity levels at lower doses of DehydraTECH-CBD.
These findings encourage further investigation into using DehydraTECH-CBD for diabetes treatment.
Lexaria Bioscience Corp. (NASDAQ: LEXX, LEXXW) has announced significant results from its clinical study HYPER-H21-4, which assessed the blood pressure-lowering effects of its DehydraTECH-processed CBD capsules. The study demonstrated a substantial and sustained reduction in blood pressure over five weeks, with no serious adverse events reported. Key findings include a 28.5% decrease in serum catestatin levels and a statistically significant drop in mean arterial pressure. These results suggest that Lexaria's CBD formulation may offer a novel therapeutic approach for managing hypertension, particularly for patients resistant to standard treatments.
Lexaria Bioscience Corp. (NASDAQ:LEXX, LEXXW) has appointed Julian Gangolli, the former President of GW Pharmaceuticals USA, as a Strategic Advisor. Gangolli, known for overseeing the FDA approval of Epidiolex, aims to assist Lexaria in commercializing its DehydraTECH technology. The company is focusing on executing its technology portfolio in 2023. Gangolli's background includes leadership roles at Allergan, further strengthening Lexaria's team. He will receive stock options for 5,000 shares at an exercise price of $2.73. Lexaria's DehydraTECH enhances drug absorption and has 28 patents granted worldwide.
Lexaria Bioscience Corp. (Nasdaq: LEXX, LEXXW) released its annual update, emphasizing resilience amid economic challenges. Despite market declines and rising inflation, Lexaria maintained its workforce and effectively managed expenses, hitting budget targets for two consecutive years. The company is progressing in discussions with several multi-billion dollar firms to license its DehydraTECH technology. Lexaria's 2022 successes include a pre-IND FDA meeting for its hypertension drug and significant institutional investment increases. Looking ahead, Lexaria aims to commercialize DehydraTECH-CBD through FDA trials and strategic partnerships in 2023.
Lexaria Bioscience Corp. (Nasdaq:LEXX)(Nasdaq:LEXXW) announced it received its first granted patent in Canada, marking its 28th globally. The Canadian Patent #3,093,414 pertains to transdermal and dermal delivery methods for cannabinoids, including CBD and THC. This advance opens new pharmaceutical applications and enhances skin-penetration of active ingredients. Past studies demonstrated a nearly 1,900% increase in CBD permeability using Lexaria's technology. The patent underscores Lexaria's innovation in drug delivery and strengthens its intellectual property portfolio.