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Legend Biotech Corp - LEGN STOCK NEWS

Welcome to our dedicated page for Legend Biotech news (Ticker: LEGN), a resource for investors and traders seeking the latest updates and insights on Legend Biotech stock.

Overview of Legend Biotech Corp

Legend Biotech Corp (NASDAQ: LEGN) is a clinical-stage biopharmaceutical company dedicated to harnessing cutting-edge cell therapy and CAR-T immunotherapy technologies to revolutionize the treatment of cancer, particularly multiple myeloma and other oncology indications. With a robust pipeline of chimeric antigen receptor (CAR) product candidates, the company leverages advanced scientific research and decades of expertise in molecular biology and immunology to address previously unmet medical needs in oncology.

Core Business and Strategic Focus

The core business of Legend Biotech revolves around the discovery, development, and clinical application of next-generation cell therapies. The company utilizes its proprietary platforms to develop CAR-T cell therapies that are designed to target and eliminate malignant cells in patients with liquid and solid tumors. By focusing on cancers that have long been considered incurable, such as multiple myeloma, Legend Biotech aims to improve treatment outcomes and extend patient survival. The company generates revenue through strategic licensing and collaboration agreements, partnering with established industry players to expand the reach of its innovative therapies.

Research, Development, and Innovation

Legend Biotech is recognized for its commitment to research and development. The company operates multiple R&D sites around the globe, ensuring a diverse and comprehensive approach to clinical research. Its teams of immunologists and molecular biologists work collaboratively to fine-tune CAR-T cell constructs and other cell-based therapies. This rigorous R&D approach has resulted in a strong pipeline of product candidates that undergo extensive clinical trials, with several therapies demonstrating promising efficacy in early and advanced stages of clinical evaluation.

Technology Platform and Pipeline

The company’s technology platform is built on the complex science of cellular engineering, enabling the development of both autologous and allogeneic cell therapies. These therapies often involve the genetic modification of a patient’s own immune cells to enhance their ability to recognize and kill cancer cells. A key product in its portfolio is a BCMA-targeted CAR-T cell therapy, which has shown significant clinical potential in treating relapsed or refractory multiple myeloma. This approach not only refines the patient’s immune response but also opens avenues for additional therapeutic applications across various oncologic disorders.

Market Position and Collaborative Strength

Within the competitive landscape of biopharmaceutical innovation, Legend Biotech positions itself as a vital contributor to the next generation of cancer treatment. The company’s involvement in high-profile clinical trials and its collaboration with major industry partners underscore its authoritative presence in the field. Its licensing and collaboration agreements with renowned organizations further reinforce its scientific credibility and operational robustness, positioning the company as an important player in global oncology research and treatment development.

Pipeline and Clinical Impact

Legend Biotech’s pipeline reflects its dedication to transforming cancer treatment paradigms. The company’s clinical trials have evaluated the safety and efficacy of its CAR-T therapies among diverse patient groups. These studies are designed to demonstrate not only impressive clinical responses but also enhancements in overall survival and quality of life among patients with challenging oncologic diagnoses. By rigorously testing its product candidates in multiple clinical settings, Legend Biotech contributes valuable data to the scientific community and paves the way for the broader adoption of cell therapies in routine clinical practice.

Scientific Rigor and Regulatory Engagement

Undergirding its product development is a strong commitment to scientific rigor and regulatory compliance. Legend Biotech adheres to strict quality standards in the development and manufacturing of its therapies, ensuring both efficacy and patient safety. Its active engagement with regulatory bodies worldwide reflects a proactive approach to meeting global standards, thereby enhancing the trust of both patients and healthcare providers in its therapies.

Commitment to Advancing Oncology Treatment

At its core, Legend Biotech is driven by the vision of overcoming the long-standing challenges in cancer treatment. By advancing the science of cell therapies, the company seeks to offer novel, potentially transformative treatments that redefine the standard of care in oncology. Its comprehensive approach, which integrates innovative research, deep scientific expertise, and strategic collaborations, enables Legend Biotech to contribute meaningfully to the evolving landscape of immunotherapy and personalized medicine.

Key Highlights

  • Innovative Cell Therapies: Focused on CAR-T cell therapies for addressing difficult-to-treat cancers, especially in the field of oncology.
  • Advanced R&D: Multiple research centers globally support expansive R&D efforts and clinical trials.
  • Collaborative Revenue Model: Strategic licensing and collaboration agreements enhance scientific advancement and market reach.
  • Clinical Expertise: Demonstrated capabilities in conducting rigorous clinical trials and generating actionable clinical data.
  • Regulatory Engagement: Active interactions with regulatory agencies ensure adherence to high quality and safety standards.

Conclusion

Legend Biotech Corp stands as a formidable entity in the field of biotechnology, focusing on the development of best-in-class immunotherapies. Through its innovative cell therapy platforms and robust clinical research programs, the company is committed to revolutionizing cancer treatment and improving patient outcomes in oncology. Its deep scientific expertise, combined with a strategic approach to R&D and global collaborations, solidifies its reputation as an authoritative and trustworthy source in the biopharmaceutical landscape.

Rhea-AI Summary
Legend Biotech Corporation (LEGN) has closed an exclusive worldwide license agreement with Novartis Pharma AG for certain Legend Biotech chimeric antigen receptor T-cell (CAR-T) cell therapies targeting Delta-like ligand protein 3 (DLL3), including Legend Biotech’s existing autologous CAR-T cell therapy candidate, LB2102 (NCT05680922). Under the terms of the agreement, Legend Biotech will receive a $100 million upfront cash payment.
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Legend Biotech Corporation (NASDAQ: LEGN) will participate in the 42nd annual J.P. Morgan Healthcare Conference. Ying Huang, Ph.D., the company’s CEO, will deliver the presentation on Tuesday, January 9, 2024, at 2:15 p.m. PT. The live audio webcast will be available on Legend’s website.
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Legend Biotech Corporation (NASDAQ: LEGN) announced that patient-reported outcome (PRO) data from the Phase 3 CARTITUDE-4 study showed clinically meaningful improvement in health-related quality of life following a single CARVYKTI® infusion in adults lenalidomide-refractory multiple myeloma (MM) patients. The as-treated population in CARTITUDE-4 demonstrated strong rates of progression-free survival and overall response. Longer-term data from CARTITUDE-2 showed deep and durable responses in earlier lines of treatment among patients.
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Legend Biotech Corporation (NASDAQ: LEGN) reported unaudited financial results for the three and nine months ended September 30, 2023. The company entered into an exclusive, global license agreement with Novartis Pharma AG for potential chimeric antigen receptor T-cell (CAR-T) therapies targeting Delta-like ligand 3 (DLL3). Novartis will pay an upfront payment of $100 million and up to $1.01 billion in milestone payments. CARVYKTI® generated approximately $152 million in net trade sales during the quarter, representing a 30% increase over the previous quarter. The company also received milestone payments and appointed a new General Counsel. Legend Biotech has $1.4 billion in cash and cash equivalents, deposits, and short-term investments as of September 30, 2023.
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Legend Biotech Corporation (NASDAQ: LEGN) has entered into an exclusive, global license agreement with Novartis Pharma AG for certain chimeric antigen receptor T-cell (CAR-T) cell therapies targeting DLL3, including its autologous CAR-T cell therapy candidate, LB2102. Legend Biotech will receive a $100M upfront payment and will be eligible to receive potential milestone payments plus tiered royalties on net sales. The deal aims to advance Legend Biotech’s autologous CAR-T cell therapy candidate, LB2102, and other potential CAR-T cell therapies targeting DLL3, using the Novartis next-generation T-Charge™ CAR-T cell therapy platform.
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Legend Biotech Corporation (NASDAQ: LEGN) will host a conference call on November 20, 2023, to review third-quarter results and provide an overview of its performance for the quarter.
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Legend Biotech Corporation will present new and updated data from the CARTITUDE clinical development program for ciltacabtagene autoleucel (cilta-cel) at the 65th American Society of Hematology Annual Meeting. The presentations will include patient-reported outcomes from the Phase 3 CARTITUDE-4 study and updated efficacy and safety data from Cohorts A and B of the Phase 2 CARTITUDE-2 study. The company aims to deliver additional treatment options to patients with unmet needs.
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Legend Biotech Corporation (NASDAQ: LEGN) submitted sBLA and Type II Variation Application for CARVYKTI® to FDA and EMA, seeking approval for earlier treatment of patients with relapsed or refractory multiple myeloma. New data from clinical studies were presented at ASCO and EHA. Financial results for the three and six months ended June 30, 2023, reported $1.5 billion in cash and cash equivalents, time deposits, and short-term investments. Legend Biotech received milestone payments and completed financings in 2023.
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FAQ

What is the current stock price of Legend Biotech (LEGN)?

The current stock price of Legend Biotech (LEGN) is $32.01 as of April 4, 2025.

What is the market cap of Legend Biotech (LEGN)?

The market cap of Legend Biotech (LEGN) is approximately 5.8B.

What is Legend Biotech Corp's core focus?

Legend Biotech focuses on developing innovative cell therapies, especially CAR-T immunotherapy, to treat challenging cancers like multiple myeloma.

How does Legend Biotech generate revenue?

The company generates revenue through strategic licensing and collaboration agreements, leveraging its innovative product pipeline and research advancements.

What distinguishes Legend Biotech's CAR-T therapies?

Their CAR-T therapies are designed using proprietary cellular engineering techniques to enhance immune cell targeting of malignant cells, demonstrating promising efficacy in clinical trials.

In which clinical areas does Legend Biotech operate?

Legend Biotech primarily operates in oncology, developing cell therapies for both liquid and solid tumors, with a significant focus on multiple myeloma.

What is the importance of the company’s R&D efforts?

Their global R&D facilities and teams of experts ensure a rigorous approach to clinical development, fostering innovation and maintaining high standards in therapeutic research.

How is Legend Biotech positioned in the global market?

Through strategic collaborations and robust clinical trial data, Legend Biotech has established itself as a respected and influential player in advanced cell therapy and cancer treatment.

What types of therapies does Legend Biotech develop?

The company develops both autologous and allogeneic cell therapies, with a strong focus on CAR-T cell therapy aimed at treating various forms of cancer.

How does Legend Biotech ensure the safety and quality of its therapies?

The company adheres to stringent quality control and regulatory standards, actively engaging with global regulatory bodies to ensure its therapies meet the highest safety and efficacy benchmarks.
Legend Biotech Corp

Nasdaq:LEGN

LEGN Rankings

LEGN Stock Data

5.85B
181.20M
1.33%
55.49%
7.14%
Biotechnology
Healthcare
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United States
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