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Lineage Cell Therapeutics, Inc. (Symbol: LCTX) is a clinical-stage biotechnology company that is pioneering the development and commercialization of novel therapies designed to address degenerative diseases. With a foundation built on pluripotent cell technology, Lineage Cell's innovative approach leverages cells capable of transforming into any type of cell in the human body. This groundbreaking capability allows for therapies aimed at regenerating or replacing damaged cells and tissues, providing hope for conditions that currently have no cure.
The company's pipeline is robust and diverse, encompassing several key product candidates:
- OpRegen: A retinal pigment epithelium transplant therapy targeting dry age-related macular degeneration, a leading cause of vision loss among the elderly.
- OPC1: An oligodendrocyte progenitor cell therapy designed to treat acute spinal cord injuries by promoting cell replacement and recovery.
- VAC2: An allogeneic cancer immunotherapy utilizing antigen-presenting dendritic cells to fight non-small cell lung cancer.
- ANP1: A promising therapy involving the transplant of allogeneic auditory neuron progenitor cells to combat hearing loss.
- PNC1: An innovative approach using allogeneic photoreceptor cell transplants aimed at treating vision loss.
Lineage Cell Therapeutics is committed to addressing large unmet medical needs through its cutting-edge technologies. The company's clinical-stage programs are supported by a premier collection of pluripotent cell assets, positioning it at the forefront of regenerative medicine.
Recent achievements include significant progress in clinical trials, strategic partnerships, and advancements in their product development pipeline. Financially, the company remains poised for growth with a clear focus on expanding its therapeutic offerings and enhancing shareholder value.
Stay informed with the latest updates and developments at Lineage Cell Therapeutics as they continue to advance their mission of transforming the treatment landscape for degenerative diseases.
Lineage Cell Therapeutics (NYSE American: LCTX) announced the appointment of Kevin Cook as the new Chief Financial Officer, effective June 21, 2021. With over 20 years of experience in strategic and operational roles, Cook has managed over $30 billion in capital raising, particularly in the life sciences sector. CEO Brian Culley expressed confidence in Cook's ability to support the company's growth as it advances its clinical programs, which include therapies for degenerative diseases. Lineage aims to become a leader in cell therapy, focusing on unmet medical needs.
Lineage Cell Therapeutics (NYSE American and TASE: LCTX) announced that CEO Brian M. Culley will present at the Raymond James 2021 Human Health Innovation Conference on June 22, 2021, at 1:20 p.m. ET. Investors can access the presentation live and archived on the company's Events and Presentations webpage. Lineage develops allogeneic cell therapies targeting significant medical needs, with products like OpRegen, OPC1, and VAC2 currently in Phase 1/2a clinical trials.
Lineage Cell Therapeutics (LCTX) announced its inclusion in the Russell 3000 and Russell Microcap Indexes, effective June 28, 2021. This recognition highlights the company's advancements in developing allogeneic cell therapies. The Russell Indexes encompass the largest U.S. stocks, with membership potentially enhancing investor outreach and liquidity. CEO Brian M. Culley stated that this achievement reflects the company’s progress and aims to capitalize on the growing field of cell therapy. The Russell Indexes influence substantial assets, with about $10.6 trillion benchmarked against them.
Lineage Cell Therapeutics, Inc. (NYSE American: LCTX) announced a webinar on June 10, 2021, at 4 PM ET, featuring experts discussing age-related macular degeneration (AMD). The company reported successful retinal tissue restoration in three patients from its OpRegen Phase 1/2a study for dry AMD, with integration of new retinal pigment epithelium cells observed. This indicates potential efficacy for OpRegen, aimed at addressing unmet medical needs in AMD treatment. The webinar will present detailed results and anatomical improvements related to OpRegen therapy.
Lineage Cell Therapeutics (LCTX) reported positive outcomes in its Phase 1/2a study of OpRegen for treating dry age-related macular degeneration (AMD). Restoration of retinal tissue was observed in two Cohort 4 patients, with significant improvements in visual acuity noted within six months. This suggests that atrophic AMD may not be irreversibly degenerative. The company has also filed a PCT patent application to protect these findings. The therapy demonstrated safety with no unexpected adverse events over more than five years of follow-up.
Lineage Cell Therapeutics, a clinical-stage biotech company, reported Q1 2021 financial results with total revenues of approximately $0.4 million, down from $0.5 million in Q1 2020, mainly due to decreased grant income. Operating expenses decreased to $7.3 million, while R&D expenses increased slightly to $3.4 million. The net loss attributable to Lineage was $1.4 million, improved from a $8.4 million loss in Q1 2020. The company highlighted operational progress in its clinical programs, particularly OpRegen, associated partnerships, and a strong cash position of $62.4 million.
Lineage Cell Therapeutics (LCTX) appointed Anula Jayasuriya, M.D., Ph.D., M.B.A., to its Board of Directors effective May 4, 2021. Dr. Jayasuriya brings extensive expertise as a healthcare investment executive and venture capitalist, with a focus on women's health. She founded EXXclaim Capital and co-founded the Evolvence India Life Science Fund. The appointment is aimed at enhancing the board's diverse expertise as Lineage pursues advancements in cell therapy and regenerative medicine with potential multi-billion-dollar market opportunities.
Lineage Cell Therapeutics, Inc. (NYSE American: LCTX) will announce its Q1 2021 financial and operating results on May 13, 2021, after U.S. markets close. Following the announcement, management will host a conference call at 4:30 p.m. ET to discuss the results and provide a business update. Interested parties can join the call by dialing the provided numbers or accessing the webcast online. Lineage specializes in allogeneic cell therapies for unmet medical needs, with significant clinical programs in retinal, spinal, and immuno-oncology treatments.
Lineage Cell Therapeutics (LCTX) presented updated interim results from its Phase 1/2a study of OpRegen at the ARVO 2021 conference. The treatment focuses on dry age-related macular degeneration (AMD) with geographic atrophy. Findings showed that 83% of Cohort 4 patients maintained or improved their visual acuity, with some achieving up to +19 letters on the ETDRS chart. The therapy demonstrated significant potential, especially with earlier intervention. No unexpected adverse events were reported, indicating OpRegen's favorable safety profile. This data supports ongoing development of OpRegen as a leading treatment option.
Lineage Cell Therapeutics (NYSE American: LCTX) announced that CEO Brian M. Culley will present at the B. Riley Securities’ Neuroscience Conference on April 28, 2021, at 1:30 p.m. ET. The presentation will be a virtual fireside chat hosted by B. Riley Equity Research. Interested investors can access the live and archived webcast on the Events and Presentations section of Lineage’s website.
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